• Vijg, Jan (PI)
  • Hinck, Andrew (PI)
  • Sarantopoulos, John (PI)
  • Curiel, Tyler J. (PI)
  • Lafer, Eileen M. (PI)
  • Padmanabhan, Swaminathan (PI)
  • I-Tien, Yeh (PI)
  • Weintraub, Susan (PI)
  • Naylor, Susan (PI)
  • Karnad, Anand (PI)
  • Pollock, Brad H. (PI)
  • Lechleiter, James (PI)
  • Mundy, Gregory (PI)
  • Thompson, Ian M. (PI)
  • Bonewald, Lynda (PI)
  • Lee, Eva (PI)
  • Leach, Robin Jean (PI)
  • Christy, Barbara (PI)
  • Herman, Brian A. (PI)
  • Allred, Craig (PI)
  • Johnson, Katherin (PI)
  • Gazitt, Yair (PI)
  • Davis, Suzanne (PI)
  • Oishi, Noboru (PI)
  • Hasty, Edward (PI)
  • Johnson, Katherine (PI)
  • Moyer, Mary (PI)
  • Windle, Jolene (PI)
  • McGill, John (PI)
  • O'Connell, Peter (PI)
  • Clark, Gary (PI)
  • Kuhn, John (PI)
  • Wolf, Robert (PI)
  • Allred, D. Craig (PI)
  • Weiss, Geoffrey (PI)
  • Boldt, David (PI)
  • Coltman, Charles (PI)
  • Curiel, Tyler J. (PI)
  • Lafer, Eileen M. (PI)
  • Pollock, Brad H. (PI)
  • Thompson, Ian M. (PI)
  • Herman, Brian A. (PI)
  • Johnson, Katherine (PI)
  • Moyer, Mary (PI)
  • Windle, Jolene (PI)
  • McGill, John (PI)
  • O'Connell, Peter (PI)
  • Clark, Gary (PI)
  • Kuhn, John (PI)
  • Wolf, Robert (PI)
  • Allred, D. Craig (PI)
  • Weiss, Geoffrey (PI)
  • Boldt, David (PI)
  • Coltman, Charles (PI)

Project: Research project

Project Details


The mission of this core facility is to provide a centralized resource
to the San Antonio Cancer Institute (SACI) for the optimal design of
cancer studies, the efficient collection and management of data from
these studies, and the appropriate analysis and presentation of study
results. By combining biostatistical, data management, and data
processing expertise in a single shared resource, coordinated by one
individual, unified and consistent services can be provided to all phases
of cancer research. A centralized facility can provide a much wider range
of statistical and computer resources to all SACI projects than would be
available to any individual project if each was required to provide all
of its own resources.

Specific Services Provided

a. Clinical trial and laboratory study support-We provide biostatistical
collaboration and consultation in the design of clinical trials and
laboratory studies. We review all research protocols and make
recommendations from a biostatistical point of view, taking into account
requirements for numbers of patients or animals, laboratory materials and
equipment, personnel, time and cost. We provide computer and software
support for patient registration, patient randomization, data management,
and computer and software support for acquisition and storage of
laboratory data.

b. Statistical analyses-We plan and perform statistical data analyses
using both packaged and special purpose computer programs, and prepare
reports and presentations of the results of the analyses. We assist in
the interpretation of study results and help plan subsequent stages of
the investigation. Biostatisticians in the facility also initiate
independent investigations of the data, applying existing statistical
techniques or developing new methodologies as required.

c. Computer service-We maintain state-of-the-art computing facilities
including a network for communication among all cancer center personnel.
We perform regular backups of all databases and computer files, install
new software and updates of existing software, evaluate and select new
hardware and software, and train new users.

d. Quality control-We plan and implement quality control procedures using
special purpose data editing computer routines. We design and implement
statistical process controls for use in our clinical and research

e. Education-We provide a wide range of educational and training support
to SACI programs and investigators. We offer formal courses and seminars
as well as informal counseling and training on statistics, computer and
network usage, data collection and management.
Effective start/end date1/1/017/31/21


  • Medicine(all)
  • Animal Science and Zoology
  • Computer Science(all)
  • Genetics
  • Molecular Biology
  • Radiology Nuclear Medicine and imaging
  • Immunology
  • Public Health, Environmental and Occupational Health
  • Drug Discovery
  • veterinary(all)
  • Safety, Risk, Reliability and Quality
  • Radiation
  • Biochemistry, Genetics and Molecular Biology(all)
  • Oncology(nursing)
  • Biochemistry
  • Spectroscopy
  • Oncology
  • Cancer Research
  • Biotechnology
  • Pediatrics, Perinatology, and Child Health
  • Cell Biology
  • Computer Science Applications
  • Pathology and Forensic Medicine
  • Statistics, Probability and Uncertainty
  • Pharmacology


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