The period from adolescence to emerging adulthood is characterized by multiple developmental transitions and peak incidence of sexually transmitted infections (STIs). Hispanic and African-American women are at high risk for HPV-associated and other sexually transmitted diseases, including cervical cancer and Chlamydia. Subsequent to the approval and release of the quadrivalent (Gardasil) HPV vaccine in 2007, we initiated a prospective cohort study of sexually-active, inner-city, minority women (aged 12-19) attending the Mount Sinai Adolescent Health Center (MSAHC), the largest comprehensive adolescent primary care facility in the U.S. We observed higher rates of HPV infection and associated cervical cytological abnormalities post-vaccination among subjects immunized at age 15 or older who took ?12 months (vs.
|Effective start/end date||2/7/18 → 1/31/19|
- National Institute of Allergy and Infectious Diseases: $927,425.00