Project Details
Description
This study examines; 1) coronary artery and heart valve calcification in individuals resilient to pathologic aging,
2) determines if these individuals have an improved ability to remove cholesterol from heart tissues as a
potential protective mechanism against cardiac calcification, and 3) explores candidate protective genes
against cardiac calcification for the overall aim of identifying new pathways which could be targeted for the
prevention or treatment of coronary artery and heart valve disease. The research addresses the National Heart
Lung and Blood Institute’s strategic research priorities on the pathobiology of calcification of coronary arteries
and heart valves, and resiliency to disease. This research also addresses the broader NHLBI mission to
prevent heart disease in older adults, so that Americans not only achieve longevity, but extended healthspan.
Status | Active |
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Effective start/end date | 2/15/20 → 1/31/23 |
Funding
- National Heart, Lung, and Blood Institute: $190,171.00
- National Heart, Lung, and Blood Institute: $190,171.00
- National Heart, Lung, and Blood Institute: $190,171.00
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