Project: Research project

Project Details


The New York City Collaborative Working Group on HIV infection in women
(NYCCWG) proposes to participate in a multisite longitudinal cohort study
to investigate the natural history of HIV in women. This project is
designed to be implemented in the context of ongoing smoothly functioning
primary care clinics in the three collaborating institutions: Bronx
Lebanon Hospital Center (BLHC), Mount Sinai Medical Center (MSMC), Beth
Israel Medical Center (BIMC). These three sites collectively provide
comprehensive HIV primary care services to more than 1300 HIV-infected
women, and several hundred known high risk HIV uninfected women. The
goal of the study is to determine the natural history of HIV in women,
including gynecologic manifestations, nongynecologic manifestations, and
behavioral factors which are related to HIV disease progression. The
cases of study include defining the relatively frequencies of specific
AIDS defining illnesses, the relationship of surrogate markers to disease
progression, the causes of morbidity and mortality, and correlates on
long term survival. Subjects will be recruited to the study by their
primary care providers and research activities will be conducted within
the context of the subjects, ongoing gynecologic screening care.
Research visits will occur every six months and will include collection
of historical data, a physical examination including pelvic, and
collection of multiple blood and gynecologic specimens. Additional
information will be obtained by review of inpatient as well as primary
care charts, and through laboratory and autopsy findings.
Effective start/end date1/1/0112/31/19


  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Medicine(all)
  • Immunology and Microbiology(all)
  • Oncology
  • History and Philosophy of Science
  • Pediatrics, Perinatology, and Child Health
  • Immunology
  • Hepatology


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