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Understanding Alzheimer's Disease in the Context of the Aging Brain

Cuervo, A. M.

National Institutes of Health

8/15/166/30/21

Project: Research projectMulti-Year Funded Research Project Grant

Autophagy
Alzheimer Disease
Brain
Homeostasis
Proteins
Obstructive Sleep Apnea
Pediatric Obesity
Hydrodynamics
Child Development
Weight Loss
Actins
Mechanical properties
Microfilament Proteins
Protein Subunits
Electron microscopy
Metabotropic Glutamate Receptors
Autophagy
Fragile X Syndrome
Brain
Fasciculation
Phosphatidylinositol 3-Kinases
Breast Neoplasms
Neoplasm Metastasis
G-Protein-Coupled Receptors
Neoplasms
Human Development
Heart Diseases
DiGeorge Syndrome
Exome
Neural Crest
Hypothalamus
Obesity
Diet
Leptin
Neurons
Prediabetic State
Hispanic Americans
Epidemiology
Microbiota
Population

Broadly Protective Bispecific Antibodies for Treatment of Ebola Virus Disease

Lai, J. R.

National Institutes of Health

7/5/166/30/19

Project: Research projectSmall Business Technology Transfer (STTR) Grants - Phase II, Small Business Technology Transfer (STTR) Grants - Phase I

Ebola Hemorrhagic Fever
Bispecific Antibodies
Ebolavirus
Viruses
Antibodies
Mycobacterium Infections
Tuberculosis
Biomarkers
HIV
Mycobacterium tuberculosis

Functional Neuroanatomy of Circuits Governing Parental Behavior

Autry-Dixon, A. E.

National Institutes of Health

7/1/165/31/21

Project: Research projectCareer Transition Award, Research Transition Award

Neuroanatomy
Urocortins
Neurons
Agonistic Behavior
Infant Behavior
Asthma
Guidelines
Technology
Referral and Consultation
Research
Single-Cell Analysis
HIV-1
RNA
T-Lymphocytes
gag Gene Products

Mechanism of Met-Induced Hepatocyte Survival

Zarnegar, R.

National Institutes of Health

6/15/165/31/21

Project: Research projectResearch Project

Receptor-Interacting Protein Serine-Threonine Kinases
Protein Kinases
Hepatocytes
Hepatocyte Growth Factor
Necrosis

Novel Strategies for the Discovery of Microbial Metabolic Pathways

Almo, S. C.

6/15/164/30/21

Project: Research projectResearch Program Projects

Carrier Proteins
Ligands
Proteins
Metabolic Networks and Pathways
Microbiota
Mediator Complex
Gene Expression Regulation
Liver
Insulin Resistance
Gene Expression
Organoids
Carcinogenesis
Castration
Prostatic Neoplasms
Neoplasms
Proteins
Muscle Strength
Cognition
Dementia
Skeletal Muscle

Resilience in HIV infected drug users

Cunningham, C. O.

National Institutes of Health

6/1/165/31/19

Project: Research projectSmall Research Grants

Drug Users
HIV
Viral Load
Cocaine
Opioid Analgesics
NFATC Transcription Factors
Gene Regulatory Networks
Coronary Vessels
Gene Expression
Developmental Biology
Immunological Synapses
Ligands
Proteins
Binding Sites
B-Cell Antigen Receptors
Autophagy
T-Lymphocytes
T-Cell Antigen Receptor
Adaptive Immunity
Regulatory T-Lymphocytes
Dioxygenases
Tryptophan
Neurodegenerative diseases
Kynurenine
Enzymes

Novel Strategies for Precision T-cell Therapies

Almo, S. C.

National Institutes of Health

6/1/165/31/21

Project: Research projectResearch Project

Immunological Synapses
Cell- and Tissue-Based Therapy
T-Lymphocytes
Biological Products
Peptides
Anorexia Nervosa
Hippocampus
Eating
Anorexia
Optogenetics

PC4PrEP: Integrating PrEP into Primary Care

Bauman, L. J.

National Institutes of Health

5/27/162/28/20

Project: Research projectResearch Project

Primary Health Care
HIV
Pre-Exposure Prophylaxis
Patient Protection and Affordable Care Act
Prescriptions

Microsporidia: invasion apparatus

Weiss, L. M.

National Institutes of Health

5/16/164/30/21

Project: Research projectResearch Project

Microsporidia
Infection
Organelles
Proteins
Post Translational Protein Processing

WNK KINASES IN DEVELOPMENT

Jenny, A.

National Institutes of Health

5/4/162/29/20

Project: Research projectResearch Project

Phosphotransferases
Catenins
Pseudohypoaldosteronism
Sodium-Potassium-Chloride Symporters
Hereditary Sensory and Autonomic Neuropathies
Obesity
Health
House Calls
Translational Medical Research
Pediatric Obesity
HIV
Magnetic Resonance Spectroscopy
Triglycerides
Fibrosis
HIV Infections
Calmodulin
Long QT Syndrome
Cardiac Arrhythmias
Mutation
Heart Diseases

HGF/HGFR Axis and Fatty Liver Disease

Zarnegar, R.

National Institutes of Health

4/1/163/31/20

Project: Research projectResearch Project

Receptor-Interacting Protein Serine-Threonine Kinases
Hepatocyte Growth Factor
Fatty Liver
Protein Kinases
Liver Diseases
Myelodysplastic Syndromes
Glutamine
Glutaminase
Therapeutics
Neoplasms
Myeloid Leukemia
Hematopoiesis
Phosphatidylinositol 3-Kinases
Protein Isoforms
Acute Myeloid Leukemia

Causally connecting neural activity to behavior with caged compounds

Nicola, S. M.

National Institutes of Health

4/1/163/31/19

Project: Research projectExploratory/Developmental Grants

Neurons
Excitatory Amino Acid Agonists
Light
Nucleus Accumbens
Glutamate Receptors
Macromolecules
Inosine Diphosphate
Intrinsically Disordered Proteins
Fluid dynamics
Phenylalanine
Huntington Disease
Oligodendroglia
Prosencephalon
Neurons
Molecular Biology
Herpes Simplex Virus Vaccines
Attenuated Vaccines
Human Herpesvirus 2
Human Herpesvirus 1
Vaccines

Antibody differentially alters Histoplasma extracellular vesicles

Nosanchuk, J. D.

National Institutes of Health

2/15/161/31/19

Project: Research projectExploratory/Developmental Grants

Histoplasma
Antibodies
Fungi
Monoclonal Antibodies
Chaperonin 60

Inhibition of methionine biosynthesis eliminates persistent M. tuberculosis.

Berney, M.

National Institutes of Health

2/15/161/31/19

Project: Research projectExploratory/Developmental Grants

Methionine
Tuberculosis
Mycobacterium tuberculosis
Pharmaceutical Preparations
Extensively Drug-Resistant Tuberculosis
glutaminyl-arginyl-phenylalanyl-seryl-arginine
Priapism
Smooth Muscle
Sickle Cell Anemia
Up-Regulation

A new molecular pathway for diabetic cardiomyopathy

Kitsis, R. N. & Yoshioka, J. U. N.

National Institutes of Health

1/15/1612/31/19

Project: Research projectResearch Project

Diabetic Cardiomyopathies
Thioredoxins
bcl-2-Associated X Protein
Hyperglycemia
Systolic Heart Failure

Tools for Exceptional Overexpression and Structural Stabilization of Membrane Proteins in Mammalian Cells

Snapp, E. L., Steinmetz, E. J., Snapp, E. L. & Gennerich, A.

National Institutes of Health

1/1/1612/31/18

Project: Research projectSmall Business Innovation Research Grants (SBIR) - Phase I

Membrane Proteins
Crystallization
Technology
Recombinant Proteins
Proteins

Develop and Apply a Novel Genome-wide Mendelian Randomization Method to Examine Relationship between Obesity and Lung Cancer

Wang, T., Ho, G. Y. F. & Ho, G. Y. F.

National Institutes of Health

12/11/1511/30/18

Project: Research projectExploratory/Developmental Grants

Random Allocation
Lung Neoplasms
Obesity
Genome
Genome-Wide Association Study

Learning and updating internal visual models

Sussman, E. S., Schwartz, O. & Kohn, A.

National Institutes of Health

9/30/156/30/19

Project: Research projectResearch Project

Visual Perception
Fatigue
Learning
Neurophysiology
Aptitude

Molecular Therapies to Promote White Matter Restoration After Traumatic Brain Injury

Chen, J. U. N., Chen, J. U. N. & Bennett, M. V. L.

National Institutes of Health

9/30/158/31/20

Project: Research projectResearch Project

Oligodendroglia
Tissue Plasminogen Activator
Peroxisome Proliferator-Activated Receptors
Cell Differentiation
Peptide Hydrolases

Tools For Imaging the Functional Genome in Living Cells and Tissues

Singer, R. H. & Darzacq, X.

National Institutes of Health

9/30/156/30/20

Project: Research projectResearch Project--Cooperative Agreements

Financial Management
Genome
Phototoxic Dermatitis
Technology
Chromosome Mapping

Tools For Imaging the Functional Genome in Living Cells and Tissues

Singer, R. H.

National Institutes of Health

9/30/156/30/20

Project: Research projectResearch Project--Cooperative Agreements

Financial Management
Genome
Phototoxic Dermatitis
Technology
Chromosome Mapping

Training of Surgeons for Studies of the Tumor Microenvironment

Libutti, S. K. & Michler, R. E.

9/25/158/31/20

Project: Research projectInstitutional National Research Service Award

Mentors
Tumor Microenvironment
Research
Neoplasms
Education

Mechanisms and therapies of B7x and B7-H3 in T1D

Zang, X.

National Institutes of Health

9/25/158/31/20

Project: Research projectResearch Project

Type 1 Diabetes Mellitus
T-Lymphocytes
Therapeutics
Pancreas
Histamine H3 Receptors