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  Prometheus: A Platform for Rapid Development of Human Antibody-based Therapeutics and Prophylactics against Emerging Viral Threats

  Chandran, K.

  National Institute of Allergy and Infectious Diseases

  2/14/19 → 1/31/22

  Project: Research project

  • Hantavirus
  • Monoclonal Antibodies
  • Crimean-Congo hemorrhagic fever virus
  • Nairovirus
  • Ebolavirus

• Hemolysis and Platelet Activation during Continuous Flow Mechanical Circulatory Support

  Saeed, O.

  National Heart, Lung, and Blood Institute

  1/15/19 → 12/31/21

  Project: Research project

  • Platelet Activation
  • Hemolysis
  • Platelet Aggregation
  • Thrombosis
  • Sildenafil Citrate

• Mechanisms of cardiovascular disease

  Kitsis, R. N. & Sibinga, N. E. S.

  National Heart, Lung, and Blood Institute

  1/1/19 → 12/31/21

  Project: Research project

  • Cardiovascular Diseases
  • Molecular Biology
  • Cardiologists
  • Vascular Diseases
  • Epigenomics

• Developmental PBDE exposure, gut microbiome, and diabetes

  Mani, S.

  National Institute of Environmental Health Sciences

  1/1/19 → 12/31/21

  Project: Research project

  • Halogenated Diphenyl Ethers
  • Gastrointestinal Microbiome
  • Dysbiosis
  • Indoles
  • Tryptophan

• Cooperative Research Agreements Related to the World Trade Center Health Program (U01)

  Webber, M. P.

  1/1/19 → 8/31/21

  Project: Research project

• Integrative, age-related changes in genome and epigenome in human lung in relation to smoking

  Vijg, J. & Spivack, S. D.

  National Heart, Lung, and Blood Institute

  1/1/19 → 12/31/21

  Project: Research project

  • Smoking
  • Genome
  • DNA Damage
  • Lung
  • Genomic Instability

• Synaptic Mechanisms for Contextual Memory Formation

  Castillo, P. E.

  National Institute of Mental Health

  12/11/18 → 11/30/21

  Project: Research project

  • Memory
  • Learning
  • Neuronal Plasticity
  • Pyramidal Cells
  • Hippocampus

• Interdisciplinary protein engineering approach to design high affinity antibodies for flaviviruses

  Fiser, A.

  National Institute of Allergy and Infectious Diseases

  11/15/18 → 10/31/21

  Project: Research project

  • Protein Engineering
  • Flavivirus
  • Antibody Affinity
  • Bacteriophages
  • Libraries

• Eradicating persistent M. tuberculosis by synthetic lethality of terminal respiratory oxidases

  Berney, M.

  National Institute of Allergy and Infectious Diseases

  11/13/18 → 10/31/21

  Project: Research project

  • Synthetic Lethal Mutations
  • Oxidoreductases
  • Mycobacterium tuberculosis
  • Tuberculosis
  • 6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phenyl)piperidin-1-yl)benzyl) imidazo(1,2-a)pyridine-3-carboxamide

• The Center of Excellence in Promoting LHS Operations and Research at Einstein/Montefiore (EXPLORE)

  Cunningham, C. O., Marantz, P. R. & Rinke, M. L.

  9/30/18 → 9/29/23

  Project: Research project

• Comprehensive Pediatric Hypertension Diagnosis and Management

  Rinke, M. L.

  9/30/18 → 7/31/21

  Project: Research project

• DYNAMICS AND TUNING OF THE MHC II PRESENTED PEPTIDOME

  Santambrogio, L.

  9/19/18 → 8/31/23

  Project: Research project

• An immunotherapeutic strategy for the induction and stabilization of remission in type 1 diabetes

  Almo, S. C., DiLorenzo, T. P. & DiLorenzo, T. P.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/15/18 → 7/31/21

  Project: Research project

  • Remission Induction
  • Type 1 Diabetes Mellitus
  • T-Lymphocytes
  • Antigens
  • Immunological Synapses

• Social Dancing Intervention for older adults at high risk of Alzheimer's disease and other dementias: A pilot study

  Blumen, H. M., Verghese, J. & Verghese, J.

  National Institute on Aging

  9/15/18 → 8/31/21

  Project: Research project

  • Dementia
  • Alzheimer Disease
  • Executive Function
  • Neuronal Plasticity
  • Cognitive Dysfunction

• UNDERSTANDING CELLULAR AND TRANSCRIPTIONAL REGULATORY CHANGES IN HUMAN AGING

  Greally, J. M.

  National Institute on Aging

  9/15/18 → 5/31/21

  Project: Research project

  • DNA Methylation
  • Epigenomics
  • T-Lymphocytes
  • Glucocorticoid Receptor Deficiency
  • Glucocorticoid Receptors

• Computational evaluation of the causal role of somatic mutations in human aging

  Dong, X.

  National Institute on Aging

  9/15/18 → 8/31/21

  Project: Research project

  • Mutation
  • B-Lymphocytes
  • Genomic Instability
  • Genome
  • Genomic Structural Variation

• The Study of Human Sulfuryl-Transfer Biology

  Leyh, T. S.

  9/8/18 → 8/31/21

  Project: Research project

• Peer mentorship to improve outcomes in patients on maintenance hemodialysis

  Melamed, M. L., Golestaneh, L., Golestaneh, L. & Melamed, M. L.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/6/18 → 7/31/21

  Project: Research project

  • Mentors
  • Renal Dialysis
  • Maintenance
  • Dialysis
  • Self-Management

• Optimizing smoking cessation interventions for PLWH in Nairobi, Kenya

  Shuter, J. & Shuter, J.

  National Cancer Institute

  9/5/18 → 8/31/21

  Project: Research project

  • Kenya
  • Smoking Cessation
  • Acquired Immunodeficiency Syndrome
  • Methadone
  • HIV

• Identifying and Reducing Disparities in Outcomes Among Economically Vulnerable and Minority Young Adults with Type 1 Diabetes

  Agarwal, S.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/1/18 → 8/31/21

  Project: Research project

  • Type 1 Diabetes Mellitus
  • Young Adult

• TREAT ECARDS: Translating Evidence into Action: Electronic Clinical Decision Support in ARDS

  Gong, M. N.

  9/1/18 → 6/30/21

  Project: Research project

• Therapeutic targeting of MDS stem cells

  Steidl, U. G.

  National Heart, Lung, and Blood Institute

  8/20/18 → 6/30/21

  Project: Research project

  • Interleukin-8
  • Stem Cells
  • Therapeutics
  • Heterografts
  • Disease Progression

• Assessing genome sequence integrity in normal human cells

  Spivack, S. D., Vijg, J. & Vijg, J.

  National Institute of Environmental Health Sciences

  8/15/18 → 5/31/21

  Project: Research project

  • Genome
  • Mutation
  • Smoke
  • Tobacco
  • DNA

• Microbial Metabolite Mimics, PXR and Colitis-Induced Colorectal Cancer

  Mani, S.

  National Cancer Institute

  8/14/18 → 7/31/21

  Project: Research project

  • Pregnane X Receptor
  • Metabolites
  • indole
  • Toll-Like Receptor 4
  • Lead compounds

• Adapting, Scaling, and Spreading an Algorithmic Asthma Mobile Intervention to Promote Patient-Reported Outcomes Within Primary Care Settings

  Jariwala, S. P.

  National Institutes of Health

  8/1/18 → 5/31/21

  Project: Research project

  • Patient Reported Outcome Measures
  • Primary Health Care
  • Asthma
  • Patient Education
  • Education

• Regulation of Nuclear Functions by Drosophila Linker Histone H1

  Fyodorov, D., Skoultchi, A. I. & Skoultchi, A. I.

  National Institute of General Medical Sciences

  8/1/18 → 5/31/21

  Project: Research project

  • Histones
  • Drosophila
  • Chromatin
  • Chromosomes
  • Post Translational Protein Processing

• PA-20-070: Adapting, implementing, and evaluating a patient-facing mobile platform to facilitate the collection of patient-reported outcomes in patients with asthma and COVID-19

  Jariwala, S. P.

  Agency for Healthcare Research and Quality

  8/1/18 → 5/31/21

  Project: Research project

  • Patient Reported Outcome Measures
  • Primary Health Care
  • Asthma
  • Patient Education
  • Education

• Calcification Propensity, using Dynamic Light Scattering, to Study Vascular Calcification in Patients with Advanced Chronic Kidney Disease

  Chen, W.

  National Institute of Diabetes and Digestive and Kidney Diseases

  8/1/18 → 5/31/21

  Project: Research project

  • Dynamic Light Scattering
  • Vascular Calcification
  • Chronic Renal Insufficiency
  • Osteocalcin
  • Biomarkers

• Machine learning-based profiles of atherosclerosis to predict disease outcomes in older HIV-infected women and men

  Hanna, D. B.

  National Institute on Aging

  8/1/18 → 4/30/21

  Project: Research project

  • Machine Learning
  • Atherosclerosis
  • HIV
  • Phenotype
  • HIV Infections

• Using cortico-striatal evolutionary innovations for modeling Huntington's disease

  Mehler, M. F.

  NIH Office of the Director

  8/1/18 → 4/30/21

  Project: Research project

  • animal models
  • mice
  • mutants
  • therapeutics
  • human diseases

• Apolipoprotein A5 and Gallstone Formation

  Wang, D. Q. H.

  7/20/18 → 4/30/22

  Project: Research project

• A Major Nutritional Effect on Intestinal Stem Cells and Tumors

  Augenlicht, L. H.

  7/17/18 → 5/31/21

  Project: Research project

• Next Generation of HPV and Cervical Cancer Research in HIV+ Women

  Strickler, H., Burk, R. D. & Strickler, H.

  National Cancer Institute

  7/11/18 → 6/30/21

  Project: Research project

  • Uterine Cervical Neoplasms
  • HIV
  • Natural History
  • Microbiota
  • Lactobacillus crispatus

• Structural, Molecular and Functional Specialization in Osteocyte Mechanosensing

  Spray, D. C.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  7/11/18 → 4/30/21

  Project: Research project

  • Osteocytes
  • Integrins
  • T-Type Calcium Channels
  • Purinergic P2X7 Receptors
  • Pharmacology

• Nutritionally Driven Sporadic Intestinal Tumors: Impact on Stem Cells

  Augenlicht, L. H.

  7/5/18 → 5/31/21

  Project: Research project

• Genetic and Dietary Interactions in MMR Deficient Colon Tumorigenesis

  Edelmann, W., Augenlicht, L. H. & Edelmann, W.

  National Cancer Institute

  7/5/18 → 5/31/21

  Project: Research project

  • Colon
  • Carcinogenesis
  • Hereditary Nonpolyposis Colorectal Neoplasms
  • villin
  • Stem Cells

• How MeCP2 discriminates epigenetic marks is still a mystery

  Brenowitz, M. D.

  National Institute of General Medical Sciences

  7/1/18 → 6/30/21

  Project: Research project

  • Epigenomics
  • Chromatin
  • Nucleotides
  • Methyl-CpG-Binding Protein 2
  • Rett Syndrome

• Acute Effects of Cannabis on Cognition and Mobility in Older HIV-Infected and Uninfected Women

  Sharma, A.

  National Institute on Aging

  7/1/18 → 5/31/21

  Project: Research project

  • Cannabis
  • Cognition
  • HIV
  • Accidental Falls
  • Walking

• Novel role and mechanisms of histone deacetylases in traumatic brain injury

  Bennett, M. V. L.

  7/1/18 → 3/31/24

  Project: Research project

• The Misdiagnosis of Cerebrovascular Disease in Emergent Headache Evaluations

  Liberman, A. L.

  National Institute of Neurological Disorders and Stroke

  7/1/18 → 6/30/21

  Project: Research project

  • Cerebrovascular Disorders
  • Diagnostic Errors
  • Headache
  • Hospital Emergency Service
  • Stroke

• Administrative Core

  Radulovic, J.

  NATIONAL INSTITUTE ON DRUG ABUSE

  7/1/18 → 6/30/21

  Project: Research project

  • Ventral Tegmental Area
  • Chronic Pain
  • Opioid Analgesics
  • Memory
  • Reward

• Rapid screening for modes-of-action of M. tuberculosis inhibitors by high-throughput metabolic fingerprinting

  Berney, M.

  National Institute of Allergy and Infectious Diseases

  6/11/18 → 5/31/21

  Project: Research project

  • Drug Discovery
  • Mycobacterium tuberculosis
  • Tuberculosis
  • Libraries
  • Genome

• Composition and formation of the cyst wall

  Weiss, L. M.

  6/1/18 → 5/31/23

  Project: Research project

• COMPARATIVE EFFECTIVENESS OF BIOLOGIC AGENTS IN ETHNIC MINORITIES WITH COLORECTAL CANCER

  Negassa, A. & Goel, S.

  National Institute on Aging

  6/1/18 → 5/31/21

  Project: Research project

  • Biological Factors
  • Colorectal Neoplasms
  • Hispanic Americans
  • Drug Therapy
  • Survival

• Thiamine as a Renal Protective Agent in Septic Shock

  Moskowitz, A. L.

  National Institute of General Medical Sciences

  6/1/18 → 5/31/21

  Project: Research project

  • Renal Agents
  • Protective Agents
  • Thiamine
  • Septic Shock
  • Sepsis

• Humoral immunity against the M. tuberculosis kasB persistent mutant

  Chan, J.

  National Institute of Allergy and Infectious Diseases

  5/15/18 → 4/30/21

  Project: Research project

  • Humoral Immunity
  • Mycobacterium tuberculosis
  • Tuberculosis
  • Bacillus
  • Mycolic Acids

• Immunoregulation by indoleamine 2,3-dioxygenases in tuberculosis

  Porcelli, S. A., Chan, J. & Porcelli, S. A.

  National Institute of Allergy and Infectious Diseases

  5/1/18 → 4/30/21

  Project: Research project

  • Indoleamine-Pyrrole 2,3,-Dioxygenase
  • Tuberculosis
  • Protein Isoforms
  • Immunosuppressive Agents
  • Kynurenine

• Development of Novel MetAP2 inhibitors as potential therapeutics for Microsporidiosis

  Weiss, L. M.

  4/1/18 → 3/31/21

  Project: Research project

• Institutional Career Development Core

  Marantz, P. R.

  National Center for Advancing Translational Sciences

  3/22/18 → 2/28/22

  Project: Research project

  • Career development
  • educational program
  • grant
  • training program
  • Healthcare

• NRSA Training Core

  Marantz, P. R.

  National Center for Advancing Translational Sciences

  3/22/18 → 2/28/22

  Project: Research project

  • grant
  • mentoring
  • training program
  • Career development
  • candidacy