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  Structure-based design of stapled peptides to target Gag-Pol and INI1 interaction to block assembly

  Kalpana, G. V.

  National Institute of Allergy and Infectious Diseases

  11/13/20 → 10/31/21

  Project: Research project

  • Integrases
  • Peptides
  • HIV-1
  • RNA
  • Integrase Inhibitors

• Evaluation of the Asthma Management Program to Promote Activity for Students in Schools (Asthma-PASS)

  Reznik, M.

  National Heart, Lung, and Blood Institute

  9/24/20 → 8/31/21

  Project: Research project

  • Asthma
  • Students
  • Exercise
  • Primary Care Physicians
  • Child

• Presynaptic forms of long-term plasticity in the CNS

  Castillo, P. E.

  National Institute of Mental Health

  9/21/20 → 7/31/21

  Project: Research project

  • Synapses
  • Axons
  • Presynaptic Terminals
  • Brain-Derived Neurotrophic Factor
  • Neuronal Plasticity

• Deciphering the enigmatic role of IGF-1 signaling in cognitive decline and Alzheimer's disease

  Huffman, D. M.

  National Institute on Aging

  9/15/20 → 8/31/21

  Project: Research project

  • Insulin-Like Growth Factor I
  • Cognitive Dysfunction
  • Alzheimer Disease
  • Amyloidosis
  • Insulin

• ANKS1B haploinsufficiency in a novel brain disorder

  Jordan, B. A.

  National Institute of Neurological Disorders and Stroke

  9/15/20 → 8/31/21

  Project: Research project

  • Haploinsufficiency
  • Brain Diseases
  • Neurodevelopmental Disorders
  • N-Methyl-D-Aspartate Receptors
  • Autistic Disorder

• BTBD9, a novel regulator of manganese-induced neurotoxicity

  Chen, P.

  National Institute of Environmental Health Sciences

  9/10/20 → 8/31/21

  Project: Research project

  • Manganese
  • Somatomedins
  • Restless Legs Syndrome
  • Caenorhabditis elegans
  • Neurobiology

• Th2A cells mediate outcomes of aspirin-exacerbated respiratory disease

  Jerschow, E.

  National Institute of Allergy and Infectious Diseases

  9/3/20 → 8/31/21

  Project: Research project

  • Th2 Cells
  • Aspirin
  • Prostaglandin D2
  • Nasal Polyps
  • prostaglandin R2 D-isomerase

• Einstein/Rwanda/DRC Consortium for Research in HIV/HPV/Malignancies

  Adedimeji, A. A., Anastos, K. & Anastos, K.

  National Cancer Institute

  9/1/20 → 8/31/21

  Project: Research project

  • Rwanda
  • Democratic Republic of the Congo
  • HIV
  • Neoplasms
  • Uterine Cervical Neoplasms

• Uncovering links between neuronal transcriptomic and functional profiles in opioid addiction

  Sjulson, L. L.

  NATIONAL INSTITUTE ON DRUG ABUSE

  9/1/20 → 7/31/21

  Project: Research project

  • Opioid-Related Disorders
  • Substance-Related Disorders
  • Self Administration
  • Opioid Analgesics
  • Optogenetics

• Adverse pregnancy outcomes in women with systemic lupus erythematosus: improving and validating risk prediction

  Kim, M.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  9/1/20 → 8/31/21

  Project: Research project

  • Pregnancy Outcome
  • Systemic Lupus Erythematosus
  • Pregnancy
  • Biostatistics
  • Research Personnel

• Cell fate choices by Tbx1 in forming the mammalian heart

  Morrow, B. E. & Zheng, D.

  National Heart, Lung, and Blood Institute

  8/20/20 → 4/30/21

  Project: Research project

  • DiGeorge Syndrome
  • Heart
  • Stem Cells
  • Mesoderm
  • Embryonic Structures

• Role of HCAR1 in glucose homeostasis

  Jo, Y.

  National Center for Advancing Translational Sciences

  8/15/20 → 8/31/21

  Project: Research project

  • brown adipose tissue
  • homeostasis
  • receptors
  • glucose
  • acids

• Multiplex Imaging of Signaling Pathways in Cell Motility

  Hodgson, L.

  National Institute of General Medical Sciences

  8/1/20 → 7/31/21

  Project: Research project

  • Biosensing Techniques
  • Energy Transfer
  • Cell Movement
  • rho GTP-Binding Proteins
  • GTP Phosphohydrolases

• Predictive analytics for cognitive decline and Alzheimer?s disease

  Ezzati, A.

  National Institute on Aging

  8/1/20 → 4/30/21

  Project: Research project

  • Cognitive Dysfunction
  • Machine Learning
  • Dementia
  • Secondary Prevention
  • Biostatistics

• Investigations Into The Molecular Pathogenesis Of Cervical Glandular Neoplasias

  Burk, R. D. & Strickler, H.

  National Cancer Institute

  7/2/20 → 6/30/21

  Project: Research project

• AIF1/Iba1 in microglial function and stroke

  Sibinga, N. E. S.

  National Institute of Neurological Disorders and Stroke

  7/1/20 → 6/30/22

  Project: Research project

• TMEM, MENAcalc, and MENAINV as Prognostic and Predictive Markers for Breast Cancer Metastasis

  Condeelis, J. S. & Rohan, T. E.

  National Cancer Institute

  7/1/20 → 6/30/21

  Project: Research project

• CCL2-CCR2b signaling in HIV-1 fitness and disease; Role of host genetic polymorphisms

  Prasad, V. R.

  National Institute of Allergy and Infectious Diseases

  7/1/20 → 5/31/21

  Project: Research project

• Structure-based Vaccine Design for CCHFV

  Chandran, K.

  National Institute of Allergy and Infectious Diseases

  6/25/20 → 5/31/21

  Project: Research project

  • Crimean-Congo hemorrhagic fever virus
  • Vaccines
  • National Institute of Allergy and Infectious Diseases (U.S.)
  • Glycoproteins
  • Ticks

• Trajectories and modifiable risk factors of brain, gait, and cognitive decline in aging and pre-dementia

  Blumen, H. M.

  6/15/20 → 3/31/21

  Project: Research project

• Single cell RNA-seq and single molecule RNA-FISH approaches to study stochasticity of latent HIV-1 reactivation

  Kalpana, G. V.

  National Institute of Allergy and Infectious Diseases

  5/20/20 → 4/30/21

  Project: Research project

  • HIV-1
  • RNA
  • Proviruses
  • Fluorescent Antibody Technique
  • Genes

• A Randomized Clinical Trial to Assess the Effectiveness of Ablative Treatments for Cervical-Cancer Risk Reduction in HIV+ Women living in Mozambique

  Castle, P. E.

  5/12/20 → 4/30/21

  Project: Research project

• A systems approach for identifying geroprotector synergy in Alzheimer?s disease

  Huffman, D. M.

  National Institute on Aging

  5/1/20 → 4/30/21

  Project: Research project

  • Systems Analysis
  • Alzheimer Disease
  • Amyloidosis
  • Gene Regulatory Networks
  • Cognition

• Molecular basis of recognition in the Immunological Synapse

  Fiser, A.

  National Institute of General Medical Sciences

  5/1/20 → 4/30/21

  Project: Research project

  • Immunological Synapses
  • Synapses
  • Ligands
  • Proteins
  • Protein Engineering

• Training in Intellectual and Developmental Disabilities (IDD) Research

  Molholm, S. & Walkley, S. U.

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  5/1/20 → 4/30/21

  Project: Research project

• Characterization of CNS protein aggregate components during acute and chronic EAE

  Shafit-Zagardo, B.

  National Institute of Neurological Disorders and Stroke

  5/1/20 → 10/31/21

  Project: Research project

  • Protein Aggregates
  • Multiple Sclerosis
  • Proteins
  • Myelin Sheath
  • Autophagy

• Novel Strategies for the Discovery of Microbial Metabolic Pathways

  Almo, S. C.

  National Institute of General Medical Sciences

  5/1/20 → 4/30/21

  Project: Research project

  • Carrier Proteins
  • Ligands
  • Proteins
  • Metabolic Networks and Pathways
  • Microbiota

• Head-mounted Photoacoustic Imaging of Deep-brain Neural Activities in Freely Behaving Animals

  Verkhusha, V.

  National Institute of Neurological Disorders and Stroke

  5/1/20 → 4/30/23

  Project: Research project

  • image analysis
  • brain
  • electrodes
  • electric potential difference
  • animal models

• AQP4 isoforms and brain edema

  Spray, D. C.

  National Institute of Neurological Disorders and Stroke

  5/1/20 → 10/31/21

  Project: Research project

  • brain
  • homeostasis
  • water
  • blood
  • distribution

• Regulation of the TGF-beta superfamily in the remodeling and failing heart

  Frangogiannis, N. G.

  National Heart, Lung, and Blood Institute

  4/3/20 → 3/31/21

  Project: Research project

  • Cardiac Myocytes
  • Transforming Growth Factor beta
  • Pressure
  • Heart
  • Fibroblasts

• Determination of genome-wide splicing kinetics and their underlying regulation

  Gamble, M. J.

  4/1/20 → 3/31/21

  Project: Research project

• Metabolic control in vascular remodeling

  Sibinga, N. E. S.

  National Heart, Lung, and Blood Institute

  3/1/20 → 1/31/21

  Project: Research project

  • Vascular Remodeling
  • Smooth Muscle Myocytes
  • Electron Transport Complex I
  • Embryonic Development
  • Vascular Diseases

• Role of the histone modifier MLL3 mutation in breast cancer cell plasticity

  Guo, W.

  National Cancer Institute

  3/1/20 → 2/28/21

  Project: Research project

  • Cell Plasticity
  • Histones
  • Breast Neoplasms
  • Mutation
  • Breast

• Characterization of brain dysfunction during development in survivors of childhood acute lymphoblastic leukemia

  Wagshul, M. E., Cole, P. D. & Sussman, E. S.

  National Cancer Institute

  3/1/20 → 2/28/21

  Project: Research project

  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Survivors
  • Brain
  • Drug Therapy
  • Therapeutics

• Activity-dependent Transcriptional Pathways Underlying Synaptic Mechanisms for Memory Discrimination and Generalization.

  Castillo, P. E.

  National Institute of Neurological Disorders and Stroke

  3/1/20 → 12/31/20

  Project: Research project

  • Generalization (Psychology)
  • Discrimination (Psychology)
  • Memory
  • Panic Disorder
  • Dentate Gyrus

• CHALO!: A mobile technology based intervention to accelerate HIV testing and linkage to prevention and treatment

  Patel, V. V.

  3/1/20 → 1/31/21

  Project: Research project

• Role of the Kinesin KIF1A in Neurological Disease

  Gennerich, A.

  National Institute of Neurological Disorders and Stroke

  2/15/20 → 12/31/20

  Project: Research project

  • Kinesin
  • Mutation
  • Brain-Derived Neurotrophic Factor
  • Biophysics
  • Optic Atrophy

• Cardiac Calcification and Cholesterol Efflux in Older Adults

  Bortnick, A. E.

  National Heart, Lung, and Blood Institute

  2/15/20 → 1/31/21

  Project: Research project

  • Cholesterol
  • Calcification of Aortic Valve
  • Parents
  • Longevity
  • Coronary Vessels

• The Rv2623-Rv1747 interaction: regulation of the in vivo fate of M. tuberculosis

  Chan, J.

  National Institute of Allergy and Infectious Diseases

  1/16/20 → 12/31/20

  Project: Research project

  • phosphatidylinositol mannoside
  • Mycobacterium tuberculosis
  • Tuberculosis
  • Cell Wall
  • Growth

• Novel effectors of insulin action in the liver

  Yang, F.

  1/3/20 → 11/30/23

  Project: Research project

• Beta Cell Intracellular Calcium and Diabetes

  Santulli, G.

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/1/20 → 11/30/21

  Project: Research project

  • Calcium
  • Type 2 Diabetes Mellitus
  • Autophagy
  • Mitochondrial Degradation
  • Insulin Secretion

• Emergence of bedaquiline and clofazimine resistance after interruption of drug-resistant TB therapy in a high HIV prevalence setting

  Brust, J. C. M.

  12/26/19 → 11/30/24

  Project: Research project

• Allosteric inhibitors targeting oncogenic BRAF V600E dimers

  Gavathiotis, E.

  National Cancer Institute

  12/1/19 → 11/30/21

  Project: Research project

  • ponatinib
  • Thyroid Neoplasms
  • Melanoma
  • Colorectal Neoplasms
  • Neoplasms

• Natural image processing in the visual cortex

  Coen Cagli, R.

  NATIONAL EYE INSTITUTE

  9/30/19 → 7/31/21

  Project: Research project

  • Visual Cortex
  • Ocular Vision
  • Population
  • Neurons
  • Machine Learning

• Early Phase Pain Investigation Clinical Network: Greater New York Clinical Center

  Lipton, R. B.

  9/30/19 → 3/31/24

  Project: Research project

• CRCNS: Probabilistic models of perceptual grouping/segmentation in natural vision

  Coen Cagli, R.

  NATIONAL EYE INSTITUTE

  9/30/19 → 7/31/21

  Project: Research project

  • Statistical Models
  • Statistics
  • Labeling
  • Image segmentation
  • Computer vision

• Molecular regulation of gut lipid metabolism by mTOR and autophagy proteins

  Singh, R.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/17/19 → 8/31/21

  Project: Research project

  • TOR Serine-Threonine Kinases
  • Autophagy
  • Lipid Metabolism
  • Triglycerides
  • Endoplasmic Reticulum

• Prometastatic Effects of Neoadjuvant Chemotherapy in Breast Cancer

  Karagiannis, G.

  National Cancer Institute

  9/16/19 → 8/31/21

  Project: Research project

  • Breast Neoplasms
  • Drug Therapy
  • Neoplasm Metastasis
  • Neoplasms
  • Tumor Microenvironment

• Power-Up: An Effectiveness Trial of the Diabetes Prevention Program Tailored for Black and Latino Men

  Chambers, E. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/16/19 → 8/31/21

  Project: Research project

  • chronic illness
  • coach
  • telephone
  • health
  • national minority

• Development of a high-resolution mapping platform for HPV DNA integration in premalignant lesions

  Lenz, J. & Montagna, C.

  National Cancer Institute

  9/16/19 → 8/31/21

  Project: Research project

  • DNA
  • Viral Genome
  • Oncogenes
  • Papanicolaou Test
  • Viral DNA