• 775 Citations
  • 11 h-Index
19992018

Research output per year

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Publications

  • 775 Citations
  • 11 h-Index
  • 15 Article
2018

The fructose-2,6-bisphosphatase TIGAR suppresses NF-B signaling by directly inhibiting the linear ubiquitin assembly complex LUBAC

Tang, Y., Kwon, H., Neel, B. A., Kasher-Meron, M., Pessin, J. B., Yamada, E. & Pessin, J. E., May 18 2018, In : Journal of Biological Chemistry. 293, 20, p. 7578-7591 14 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function

Chung, Y. W., Ahmad, F., Tang, Y., Hockman, S. C., Kee, H. J., Berger, K., Guirguis, E., Choi, Y. H., Schimel, D. M., Aponte, A. M., Park, S., Degerman, E. & Manganiello, V. C., Jan 13 2017, In : Scientific reports. 7, 40445.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
2016

Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue

Ahmad, F., Chung, Y. W., Tang, Y., Hockman, S. C., Liu, S., Khan, Y., Huo, K., Billings, E., Amar, M. J., Remaley, A. T. & Manganiello, V. C., Jun 20 2016, In : Scientific Reports. 6, 28056.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
2014

Adipocyte-Specific IKKβ Signaling Suppresses Adipose Tissue Inflammation through an IL-13-Dependent Paracrine Feedback Pathway

Kwon, H., Laurent, S., Tang, Y., Zong, H., Vemulapalli, P. & Pessin, J. E., Dec 11 2014, In : Cell Reports. 9, 5, p. 1574-1583 10 p.

Research output: Contribution to journalArticle

25 Scopus citations
2011
51 Scopus citations
2009

Autophagy regulates adipose mass and differentiation in mice

Singh, R., Xiang, Y., Wang, Y., Baikati, K., Cuervo, A. M., Luu, Y. K., Tang, Y., Pessin, J. E., Schwartz, G. J. & Czaja, M. J., Nov 2 2009, In : Journal of Clinical Investigation. 119, 11, p. 3329-3339 11 p.

Research output: Contribution to journalArticle

480 Scopus citations

Differential regulation of adipocyte PDE3B in distinct membrane compartments by insulin and the β3-adrenergic receptor agonist CL316243: Effects of caveolin-1 knockdown on formation/ maintenance of macromolecular signalling complexes

Ahmad, F., Lindh, R., Tang, Y., Ruishalme, I., Ost, A., Sahachartsiri, B., Strålfors, P., Degerman, E. & Manganiello, V. C., Dec 15 2009, In : Biochemical Journal. 424, 3, p. 399-410 12 p.

Research output: Contribution to journalArticle

33 Scopus citations
2007

Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB

Ahmad, F., Lindh, R., Tang, Y., Weston, M., Degerman, E. & Manganiello, V. C., Jun 1 2007, In : Biochemical Journal. 404, 2, p. 257-268 12 p.

Research output: Contribution to journalArticle

43 Scopus citations
2006

Effect of adipocyte β 3-adrenergic receptor activation on the type 2 diabetic MKR mice

Kim, H., Pennisi, P. A., Gavrilova, O., Pack, S., Jou, W., Setser-Portas, J., East-Palmer, J., Tang, Y., Manganiello, V. C. & LeRoith, D., Jun 14 2006, In : American Journal of Physiology - Endocrinology and Metabolism. 290, 6, p. E1227-E1236

Research output: Contribution to journalArticle

44 Scopus citations
2005

Adenovirus-mediated overexpression of murine cyclic nucleotide phosphodiesterase 3B.

Ahmad, F., Härndahl, L., Tang, Y., Holst, L. S. & Manganiello, V. C., 2005, In : Methods in molecular biology (Clifton, N.J.). 307, p. 93-107 15 p.

Research output: Contribution to journalArticle

1 Scopus citations
2003

Reduction of phosphodiesterase 3B gene expression in peroxisome proliferator-activated receptor γ (+/-) mice independent of adipocyte size

Ogura, T., Osawa, H., Tang, Y., Onuma, H., Ochi, M., Nishimiya, T., Kubota, N., Terauchi, Y., Kadowaki, T. & Makino, H., May 8 2003, In : FEBS Letters. 542, 1-3, p. 65-68 4 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2002

Differential regulation of gene expression and insulin-induced activation of phosphodiesterase 3B in adipocytes of lean insulin-resistant IRS-1 (-/-) mice

Hasegawa, M., Tang, Y., Osawa, H., Onuma, H., Nishimiya, T., Ochi, M., Terauchi, Y., Kadowaki, T. & Makino, H., Nov 1 2002, In : Diabetes Research and Clinical Practice. 58, 2, p. 79-85 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2001

Adipocyte-specific reduction of phosphodiesterase 3B gene expression and its restoration by JTT-501 in the obese, diabetic KKAy mouse

Tang, Y., Osawa, H., Onuma, H., Hasegawa, M., Nishimiya, T., Ochi, M. & Makino, H., Jan 1 2001, In : European Journal of Endocrinology. 145, 1, p. 93-99 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Phosphodiesterase 3B gene expression is enhanced in the liver but reduced in the adipose tissue of obese insulin resistant db/db mouse

Tang, Y., Osawa, H., Onuma, H., Nishimiya, T., Ochi, M., Sugita, A. & Makino, H., Nov 10 2001, In : Diabetes Research and Clinical Practice. 54, 3, p. 145-155 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
1999

Improvement in insulin resistance and the restoration of reduced phosphodiesterase 3B gene expression by pioglitazone in adipose tissue of obese diabetic KKAy mice

Tang, Y., Osawa, H., Onuma, H., Nishimiya, T., Ochi, M. A. & Makino, H., Sep 11 1999, In : Diabetes. 48, 9, p. 1830-1835 6 p.

Research output: Contribution to journalArticle

38 Scopus citations