• 12055 Citations
  • 59 h-Index
1977 …2023
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  • 9 Similar Profiles
DNA Mismatch Repair Medicine & Life Sciences
Mutation Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Genetic Recombination Medicine & Life Sciences
Genes Medicine & Life Sciences
Adenomatous Polyposis Coli Medicine & Life Sciences
DNA Damage Medicine & Life Sciences

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Grants 1977 2023

Colon
Carcinogenesis
Hereditary Nonpolyposis Colorectal Neoplasms
Stem Cells
Penetrance

DNA MISMATCH REPAIR AND CANCER IN MURINE MODELS

Edelmann, W.

National Institutes of Health

12/1/973/31/19

Project: Research projectResearch Project

DNA Mismatch Repair
Neoplasms
Mutation
DNA Damage
Carcinogenesis

CANCER RESEARCH CENTER

Brewer, C. F., Bases, R., Kadish, A., Wiernik, P., Orr, G., Bloom, B., Shapiro, L., Lilly, F., Chase, J., Atkinson, P., Maio, J., Reid, L., Levine, W., Nathenson, S., Fant, J., Warner, J., Peisach, J., Horwitz, M., Krauter, K., Makman, M., Blumenfeld, O., Schulman, L., Klinger, H., Rajan, T., Wadler, S., Chance, M., Buhl, S., Desai, K., Pollard, J. W., Brenowitz, M. D., Stanley, P., Skoultchi, A. I., Sparano, J. A., Hurwitz, J., Duran-Reynals, M., Serrano, L., Alderman, M., Shin, S., West, M., Birshstein, B., Marians, K., Eagle, H., Russel, R., Grills, G., Pickering, K., Mahmood, R., Keller, S. M., Herbst, L., Seither, R., Satir, B. H., Rubin, C. S., Scharff, M. D., Maitra, U., Band Horwitz, S., Schildkraut, C. L., Ho, G. Y. F., Cannizzaro, L. A., Childs, G. J., Augenlicht, L. H., Almo, S. C., Greally, J. M., Angeletti, R. H., Porcelli, S. A., Morrow, B. E., Condeelis, J. S., Montagna, C., Edelmann, W., Kim, M., Rohan, T. E., Goldman, I. D., Kucherlapati, R., Gupta, R., Depinho, R., Dutcher, J., Diamond, B., Gaertner, D. J., Keller, S. M., Pollard, J. W., Kucherlapati, R., Gupta, R., Depinho, R., Dutcher, J., Diamond, B., Gaertner, D. J. & Keller, S. M.

National Institutes of Health

6/1/776/30/19

Project: Research projectCenter Core Grants

Research Personnel
Organized Financing
Neoplasms
Research
Medical Oncology

Identifying Conserved Genetic Networks for Eukaryotic MMR Genes

Edelmann, W.

National Institutes of Health

4/1/113/31/13

Project: Research projectExploratory/Developmental Grants

DNA Mismatch Repair
Hereditary Nonpolyposis Colorectal Neoplasms
Genes
Neoplasms
Colorectal Neoplasms

Exonuclease 1 in DNA Meiosis, Mismatch Repair and Canc

Edelmann, W.

National Institutes of Health

1/1/025/31/13

Project: Research projectResearch Project

DNA Mismatch Repair
Meiosis
DNA Repair
Neoplasms
Missense Mutation

Publications 1989 2018

  • 12055 Citations
  • 59 h-Index
  • 150 Article
  • 1 Chapter

MutLγ promotes repeat expansion in a Fragile X mouse model while EXO1 is protective

Zhao, X., Zhang, Y., Wilkins, K., Edelmann, W. & Usdin, K., Oct 1 2018, In : PLoS genetics. 14, 10, e1007719.

Research output: Contribution to journalArticle

DNA Mismatch Repair
nucleases
repair
animal models
Germ Cells

EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells

Chen, C. C., Avdievich, E., Zhang, Y., Zhang, Y., Wei, K., Lee, K., Edelmann, W., Jasin, M. & LaRocque, J. R., Sep 1 2017, In : DNA Repair. 57, p. 98-106 9 p.

Research output: Contribution to journalArticle

Homologous Recombination
Repair
Cells
DNA Mismatch Repair
DNA
1 Citations

The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells

Kokavec, J., Zikmund, T., Savvulidi, F., Kulvait, V., Edelmann, W., Skoultchi, A. I. & Stopka, T., Jun 1 2017, In : Stem Cells. 35, 6, p. 1614-1623 10 p.

Research output: Contribution to journalArticle

Erythroblasts
Erythroid Cells
Hematopoiesis
Hematopoietic Stem Cells
Adenosine Triphosphatases
4 Citations

A novel chemotherapeutic agent to treat tumors with DNA mismatch repair deficiencies

Zhang, Y., Fox, J. T., Park, Y. U., Elliott, G., Rai, G., Cai, M., Sakamuru, S., Huang, R., Xia, M., Lee, K., Jeon, M. H., Mathew, B. P., Park, H. D., Edelmann, W., Park, C. Y., Hong, S. Y., Maloney, D. & Myung, K., Jul 15 2016, In : Cancer Research. 76, 14, p. 4183-4191 9 p.

Research output: Contribution to journalArticle

DNA Repair-Deficiency Disorders
DNA Mismatch Repair
Neoplasms
Colon
Double-Stranded DNA Breaks
8 Citations

Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation

He, S., Limi, S., McGreal, R. S., Xie, Q., Brennan, L. A., Kantorow, W. L., Kokavec, J., Majumdar, R., Hou, H., Edelmann, W., Liu, W., Ashery-Padan, R., Zavadil, J., Kantorow, M., Skoultchi, A. I., Stopka, T. & Cvekl, A., Jun 1 2016, In : Development (Cambridge). 143, 11, p. 1937-1947 11 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Lenses
Enzymes
Cell Differentiation
Gene Expression