Projects per year
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- 9 Similar Profiles
DNA Mismatch Repair
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Carcinogenesis
Medicine & Life Sciences
Genetic Recombination
Medicine & Life Sciences
Genes
Medicine & Life Sciences
Adenomatous Polyposis Coli
Medicine & Life Sciences
DNA Damage
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 1977 2023
Genetic and Dietary Interactions in MMR Deficient Colon Tumorigenesis
Augenlicht, L. H. & Edelmann, W.
7/5/18 → 5/31/23
Project: Research project › Research Project
Colon
Carcinogenesis
Hereditary Nonpolyposis Colorectal Neoplasms
Stem Cells
Penetrance
DNA MISMATCH REPAIR AND CANCER IN MURINE MODELS
12/1/97 → 3/31/19
Project: Research project › Research Project
DNA Mismatch Repair
Neoplasms
Mutation
DNA Damage
Carcinogenesis
CANCER RESEARCH CENTER
Brewer, C. F., Bases, R., Kadish, A., Wiernik, P., Orr, G., Bloom, B., Shapiro, L., Lilly, F., Chase, J., Atkinson, P., Maio, J., Reid, L., Levine, W., Nathenson, S., Fant, J., Warner, J., Peisach, J., Horwitz, M., Krauter, K., Makman, M., Blumenfeld, O., Schulman, L., Klinger, H., Rajan, T., Wadler, S., Chance, M., Buhl, S., Desai, K., Pollard, J. W., Brenowitz, M. D., Stanley, P., Skoultchi, A. I., Sparano, J. A., Hurwitz, J., Duran-Reynals, M., Serrano, L., Alderman, M., Shin, S., West, M., Birshstein, B., Marians, K., Eagle, H., Russel, R., Grills, G., Pickering, K., Mahmood, R., Keller, S. M., Herbst, L., Seither, R., Satir, B. H., Rubin, C. S., Scharff, M. D., Maitra, U., Band Horwitz, S., Schildkraut, C. L., Ho, G. Y. F., Cannizzaro, L. A., Childs, G. J., Augenlicht, L. H., Almo, S. C., Greally, J. M., Angeletti, R. H., Porcelli, S. A., Morrow, B. E., Condeelis, J. S., Montagna, C., Edelmann, W., Kim, M., Rohan, T. E., Goldman, I. D., Kucherlapati, R., Gupta, R., Depinho, R., Dutcher, J., Diamond, B., Gaertner, D. J., Keller, S. M., Pollard, J. W., Kucherlapati, R., Gupta, R., Depinho, R., Dutcher, J., Diamond, B., Gaertner, D. J. & Keller, S. M.
6/1/77 → 6/30/19
Project: Research project › Center Core Grants
Research Personnel
Organized Financing
Neoplasms
Research
Medical Oncology
Identifying Conserved Genetic Networks for Eukaryotic MMR Genes
4/1/11 → 3/31/13
Project: Research project › Exploratory/Developmental Grants
DNA Mismatch Repair
Hereditary Nonpolyposis Colorectal Neoplasms
Genes
Neoplasms
Colorectal Neoplasms
Exonuclease 1 in DNA Meiosis, Mismatch Repair and Canc
1/1/02 → 5/31/13
Project: Research project › Research Project
DNA Mismatch Repair
Meiosis
DNA Repair
Neoplasms
Missense Mutation
Publications 1989 2018
MutLγ promotes repeat expansion in a Fragile X mouse model while EXO1 is protective
Zhao, X., Zhang, Y., Wilkins, K., Edelmann, W. & Usdin, K., Oct 1 2018, In : PLoS genetics. 14, 10, e1007719.Research output: Contribution to journal › Article
DNA Mismatch Repair
nucleases
repair
animal models
Germ Cells
EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells
Chen, C. C., Avdievich, E., Zhang, Y., Zhang, Y., Wei, K., Lee, K-R., Edelmann, W., Jasin, M. & LaRocque, J. R., Sep 1 2017, In : DNA Repair. 57, p. 98-106 9 p.Research output: Contribution to journal › Article
Homologous Recombination
Repair
Cells
DNA Mismatch Repair
DNA
The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells
Kokavec, J., Zikmund, T., Savvulidi, F., Kulvait, V., Edelmann, W., Skoultchi, A. I. & Stopka, T., Jun 1 2017, In : Stem Cells. 35, 6, p. 1614-1623 10 p.Research output: Contribution to journal › Article
Erythroblasts
Erythroid Cells
Hematopoiesis
Hematopoietic Stem Cells
Adenosine Triphosphatases
A novel chemotherapeutic agent to treat tumors with DNA mismatch repair deficiencies
Zhang, Y., Fox, J. T., Park, Y. U., Elliott, G., Rai, G., Cai, M., Sakamuru, S., Huang, R., Xia, M., Lee, K-R., Jeon, M. H., Mathew, B. P., Park, H. D., Edelmann, W., Park, C. Y., Hong, S. Y., Maloney, D. & Myung, K., Jul 15 2016, In : Cancer Research. 76, 14, p. 4183-4191 9 p.Research output: Contribution to journal › Article
DNA Repair-Deficiency Disorders
DNA Mismatch Repair
Neoplasms
Colon
Double-Stranded DNA Breaks
Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation
He, S., Limi, S., Estrada, R. S., Xie, Q., Brennan, L. A., Kantorow, W. L., Kokavec, J., Majumdar, R., Hou, H., Edelmann, W., Liu, W., Ashery-Padan, R., Zavadil, J., Kantorow, M., Skoultchi, A. I., Stopka, T. & Cvekl, A., Jun 1 2016, In : Development (Cambridge). 143, 11, p. 1937-1947 11 p.Research output: Contribution to journal › Article
Chromatin Assembly and Disassembly
Lenses
Enzymes
Cell Differentiation
Gene Expression