Projects per year
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Collaborations and top research areas from the last five years
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Analyzing the Hypersensitivity of MMR-deficient Colorectal Cancers to mTOR Inhibition and the Response of Cancer Stem Cells
4/1/21 → 3/31/24
Project: Research project
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Cancer Center Support Grant
Almo, S. C., Hogue-Angeletti, R., Augenlicht, L. H., Condeelis, J. S., Desai, K., Edelmann, W., Goldman, I. D., Greally, J. M., Herbst, L. H., Keller, S. M., Kim, M. Y., Mahmood, R., Montagna, C., Morrow, B. E., Pollard, J. W., Porcelli, S. A., Rohan, T. E., Scharff, M. D., Seither, R., Skoultchi, A. I., Sparano, J. A., Stanley, P. M., Chu, E. E., Bresnick, A. R., Skoultchi, A. I., Adedimeji, A. A., Beck, A. P., Blanchard, J. S., Halmos, B., Diamond, B. B., Rapkin, B. D., Chu, E., Stein, D. T., Gaertner, D. D. J., Chu, E., Ho, G. Y. F., Goel, S., Hosgood, H. D. H., Strickler, H., Pollard, J. J. W., Condeelis, J. S., Dutcher, J. P., Backer, J. M., Sparano, J., Aguirre-ghiso, J. J. A., Gritsman, K., Herbst, L. H., Augenlicht, L. H., Cannizzaro, L. A., Hackett, L. L. E., Scharff, M. D., Brenowitz, M. D., Kim, M., Ohri, N., Stanley, P., Gupta, R. R. K., Seither, R. R. L., Depinho, R. R. A., Kucherlapati, R. R. S., Schramm, V. L., Keller, S. M., Porcelli, S. A., Rohan, T. E., Steidl, U. U. G., Xue, X., Alderman, M. H., Atkinson, P. H., Bases, R. E., Birshstein, B. K., Bloom, B. R., Blumenfeld, O. O., Brenowitz, M. D., Brewer, F. C., Buhl, S., Chance, M. R., Chase, J. W., Childs, G. J., Depinho, R., Depinho, R. A., Duran-reynals, M. L., Dutcher, J. P., Eagle, H., Fant, J., Gaertner, D. J., Grills, G., Gupta, R. K., Ho, G. Y., Band Horwitz, S., Horwitz, M. S., Hurwitz, J., Kadish, A. S., Klinger, H. P., Krauter, K. S., Kucherlapati, R. S., Levine, W. G., Lilly, F., Maio, J. J., Maitra, U., Makman, M. H., Marians, K. J., Nathenson, S. G., Orr, G. A., Peisach, J., Pickering, K., Rajan, T. V., Reid, L. M., Rubin, C. S., Russel, R., Satir, B. H., Schildkraut, C. L., Schulman, L. H., Serrano, L. J., Shapiro, L., Shin, S., Wadler, S. H., Warner, J. R., West, M. & Wiernik, P. H.
6/1/85 → 6/30/24
Project: Research project
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Analyzing the Hypersensitivity of MMR-deficient Colorectal Cancers to mTOR Inhibition and the Response of Cancer Stem Cells
4/1/21 → 3/31/22
Project: Research project
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Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition
Bedard, G. T., Gilaj, N., Peregrina, K., Brew, I., Tosti, E., Shaffer, K., Tyler, P. C., Edelmann, W., Augenlicht, L. H. & Schramm, V. L., Jan 2024, In: Journal of Biological Chemistry. 300, 1, 105492.Research output: Contribution to journal › Article › peer-review
Open Access -
Vaccination and Microbiota Manipulation Approaches for Colon Cancer Prevention in Rodent Models
Tosti, E., Srivastava, N. & Edelmann, W., Aug 1 2023, In: Cancer Prevention Research. 16, 8, p. 429-438 10 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Blockade of the immunosuppressive KIR2DL5/PVR pathway elicits potent human NK cell–mediated antitumor immunity
Ren, X., Peng, M., Xing, P., Wei, Y., Galbo, P. M., Corrigan, D., Wang, H., Su, Y., Dong, X., Sun, Q., Li, Y., Zhang, X., Edelmann, W., Zheng, D. & Zang, X., Nov 15 2022, In: Journal of Clinical Investigation. 132, 22, e163620.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Genome Replication Is Associated With Release of Immunogenic DNA Waste
Schubert, N., Schumann, T., Daum, E., Flade, K., Ge, Y., Hagedorn, L., Edelmann, W., Müller, L., Schmitz, M., Kuut, G., Hornung, V., Behrendt, R. & Roers, A., May 11 2022, In: Frontiers in immunology. 13, 880413.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Loss of MMR and TGFBR2 Increases the Susceptibility to Microbiota-Dependent Inflammation-Associated Colon Cancer
Tosti, E., Almeida, A. S., Tran, T. T. T., Barbachan e Silva, M., Broin, P., Dubin, R., Chen, K., Beck, A. P., Mclellan, A. S., Vilar, E., Golden, A., O'Toole, P. W. & Edelmann, W., Jan 2022, In: CMGH. 14, 3, p. 693-717 25 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations