• 12309 Citations
  • 59 h-Index
1977 …2023
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  • 10 Similar Profiles
DNA Mismatch Repair Medicine & Life Sciences
Mutation Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Genetic Recombination Medicine & Life Sciences
Genes Medicine & Life Sciences
Adenomatous Polyposis Coli Medicine & Life Sciences
DNA Damage Medicine & Life Sciences

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Grants 1977 2023

Colon
Carcinogenesis
Hereditary Nonpolyposis Colorectal Neoplasms
Stem Cells
Penetrance

CANCER RESEARCH CENTER

Brewer, C. F., Bases, R., Kadish, A., Wiernik, P., Orr, G., Bloom, B., Shapiro, L., Lilly, F., Chase, J., Atkinson, P., Maio, J., Reid, L., Levine, W., Nathenson, S., Fant, J., Warner, J., Peisach, J., Horwitz, M., Krauter, K., Makman, M., Blumenfeld, O., Schulman, L., Klinger, H., Rajan, T., Wadler, S., Chance, M., Buhl, S., Desai, K., Pollard, J. W., Brenowitz, M. D., Stanley, P., Skoultchi, A. I., Sparano, J. A., Hurwitz, J., Duran-Reynals, M., Serrano, L., Alderman, M., Shin, S., West, M., Birshstein, B., Marians, K., Eagle, H., Russel, R., Grills, G., Pickering, K., Mahmood, R., Keller, S. M., Herbst, L., Seither, R., Satir, B. H., Rubin, C. S., Scharff, M. D., Maitra, U., Band Horwitz, S., Schildkraut, C. L., Ho, G. Y. F., Cannizzaro, L. A., Childs, G. J., Augenlicht, L. H., Almo, S. C., Greally, J. M., Angeletti, R. H., Porcelli, S. A., Morrow, B. E., Condeelis, J. S., Montagna, C., Edelmann, W., Kim, M., Rohan, T. E., Goldman, I. D., Kucherlapati, R., Gupta, R., Depinho, R., Dutcher, J., Diamond, B., Gaertner, D. J., Keller, S. M., Pollard, J. W., Kucherlapati, R., Gupta, R., Depinho, R., Dutcher, J., Diamond, B., Gaertner, D. J. & Keller, S. M.

National Institutes of Health

6/1/776/30/19

Project: Research project

Research Personnel
Organized Financing
Neoplasms
Research
Medical Oncology
DNA Mismatch Repair
Hereditary Nonpolyposis Colorectal Neoplasms
Genes
Neoplasms
Colorectal Neoplasms
DNA Mismatch Repair
Meiosis
DNA Repair
Neoplasms
Missense Mutation
DNA Mismatch Repair
Neoplasms
Mutation
DNA Damage
Carcinogenesis

Publications 1989 2018

  • 12309 Citations
  • 59 h-Index
  • 150 Article
  • 1 Chapter
1 Citation (Scopus)

MutLγ promotes repeat expansion in a Fragile X mouse model while EXO1 is protective

Zhao, X., Zhang, Y., Wilkins, K., Edelmann, W. & Usdin, K., Oct 1 2018, In : PLoS Genetics. 14, 10, e1007719.

Research output: Contribution to journalArticle

DNA Mismatch Repair
nucleases
repair
animal models
Germ Cells

EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells

Chen, C. C., Avdievich, E., Zhang, Y., Zhang, Y., Wei, K., Lee, K-R., Edelmann, W., Jasin, M. & LaRocque, J. R., Sep 1 2017, In : DNA Repair. 57, p. 98-106 9 p.

Research output: Contribution to journalArticle

Homologous Recombination
Repair
Cells
DNA Mismatch Repair
DNA
3 Citations (Scopus)

The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells

Kokavec, J., Zikmund, T., Savvulidi, F., Kulvait, V., Edelmann, W., Skoultchi, A. I. & Stopka, T., Jun 1 2017, In : Stem Cells. 35, 6, p. 1614-1623 10 p.

Research output: Contribution to journalArticle

Erythroblasts
Erythroid Cells
Hematopoiesis
Hematopoietic Stem Cells
Adenosine Triphosphatases
4 Citations (Scopus)

A novel chemotherapeutic agent to treat tumors with DNA mismatch repair deficiencies

Zhang, Y., Fox, J. T., Park, Y. U., Elliott, G., Rai, G., Cai, M., Sakamuru, S., Huang, R., Xia, M., Lee, K-R., Jeon, M. H., Mathew, B. P., Park, H. D., Edelmann, W., Park, C. Y., Hong, S. Y., Maloney, D. & Myung, K., Jul 15 2016, In : Cancer Research. 76, 14, p. 4183-4191 9 p.

Research output: Contribution to journalArticle

DNA Repair-Deficiency Disorders
DNA Mismatch Repair
Neoplasms
Colon
Double-Stranded DNA Breaks
9 Citations (Scopus)

Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation

He, S., Limi, S., Estrada, R. S., Xie, Q., Brennan, L. A., Kantorow, W. L., Kokavec, J., Majumdar, R., Hou, H., Edelmann, W., Liu, W., Ashery-Padan, R., Zavadil, J., Kantorow, M., Skoultchi, A. I., Stopka, T. & Cvekl, A., Jun 1 2016, In : Development (Cambridge). 143, 11, p. 1937-1947 11 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Lenses
Enzymes
Cell Differentiation
Gene Expression