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William C. Drosopoulos, Ph.D.

  • 842 Citations
  • 15 h-Index
19962017
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  • 3 Similar Profiles
HIV-1 Medicine & Life Sciences
Telomere Medicine & Life Sciences
RNA-Directed DNA Polymerase Medicine & Life Sciences
Telomerase Medicine & Life Sciences
Lamivudine Medicine & Life Sciences
Mutation Medicine & Life Sciences
Nucleosides Medicine & Life Sciences
Reverse Transcriptase Inhibitors Medicine & Life Sciences

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Grants 2000 2007

STRUCTURE/FUNCTION STUDIES ON HUMAN TELOMERASE

Drosopoulos, W. C.

National Institutes of Health

8/11/00 → 1/31/07

Project: Research project

Telomerase
Research
Neoplasms
HIV Reverse Transcriptase
RNA-Directed DNA Polymerase

Publications 1996 2017

  • 842 Citations
  • 15 h-Index
  • 17 Article
21 Citations (Scopus)

FANCM, BRCA1, and BLM cooperatively resolve the replication stress at the ALT telomeres

Pan, X., Drosopoulos, W. C., Sethi, L., Madireddy, A., Schildkraut, C. L. & Zhang, D., Jul 18 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 29, p. E5940-E5949

Research output: Contribution to journal › Article

Telomere Homeostasis
Telomere
Centromere
Homologous Recombination
DNA
51 Citations (Scopus)

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

Drosopoulos, W. C., Kosiyatrakul, S. T. & Schildkraut, C. L., 2015, In : Journal of Cell Biology. 210, 2, p. 191-208 18 p.

Research output: Contribution to journal › Article

Telomere
DNA
Bloom Syndrome
G-Quadruplexes
Genome
16 Citations (Scopus)

Single molecule analysis of Trypanosoma brucei DNA replication dynamics

Calderano, S. G., Drosopoulos, W. C., Quaresma, M. M., Marques, C. A., Kosiyatrakul, S., McCulloch, R., Schildkraut, C. L. & Elias, M. C., Mar 11 2015, In : Nucleic Acids Research. 43, 5, p. 2655-2665 11 p.

Research output: Contribution to journal › Article

Trypanosoma brucei brucei
Replication Origin
DNA Replication
Chromosomes, Human, Pair 1
Chromosomes
94 Citations (Scopus)

Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres

Remeseiro, S., Cuadrado, A., Carretero, M., Mart́nez, P., Drosopoulos, W. C., Cañamero, M., Schildkraut, C. L., Blasco, M. A. & Losada, A., May 2 2012, In : EMBO Journal. 31, 9, p. 2076-2089 14 p.

Research output: Contribution to journal › Article

Telomere
Aneuploidy
Antigens
Chromosome Segregation
Defects
37 Citations (Scopus)

Human telomeres replicate using chromosomespecific, rather than universal, replication programs

Drosopoulos, W. C., Kosiyatrakul, S. T., Yan, Z., Calderano, S. G. & Schildkraut, C. L., Apr 2012, In : Journal of Cell Biology. 197, 2, p. 253-266 14 p.

Research output: Contribution to journal › Article

Telomere
Chromosomes
DNA Replication
Heterochromatin
Human Chromosomes