• 11704 Citations
  • 19 h-Index
20012020

Research output per year

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Publications

  • 11704 Citations
  • 19 h-Index
  • 25 Article
  • 3 Review article
  • 2 Chapter
  • 2 Comment/debate
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Article
2001

Integrin-specific activation of Rac controls progression through the G1 phase of the cell cycle

Mettouchi, A., Klein, S., Guo, W., Lopez-Lago, M., Lemichez, E., Westwick, J. K. & Giancotti, F. G., Jan 1 2001, In : Molecular Cell. 8, 1, p. 115-127 13 p.

Research output: Contribution to journalArticle

229 Scopus citations
2004

Integrin β4 signaling promotes tumor angiogenesis

Nikolopoulos, S. N., Blaikie, P., Yoshioka, T., Guo, W. & Giancotti, F. G., Nov 1 2004, In : Cancer Cell. 6, 5, p. 471-483 13 p.

Research output: Contribution to journalArticle

166 Scopus citations
2005

p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow

Vidal, A., Zacharoulis, S., Guo, W., Shaffer, D., Giancotti, F., Bramley, A. H., De La Hoz, C., Jensen, K. K., Kato, D., MacDonald, D. D., Knowles, J., Yeh, N., Frohman, L. A., Rafii, S., Lyden, D. & Koff, A., May 10 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 19, p. 6890-6895 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Targeted deletion of the integrin β4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-κB, causing defects in epidermal growth and migration

Nikolopoulos, S. N., Blaikie, P., Yoshioka, T., Guo, W., Puri, C., Tacchetti, C. & Giancotti, F. G., Jul 1 2005, In : Molecular and cellular biology. 25, 14, p. 6090-6102 13 p.

Research output: Contribution to journalArticle

99 Scopus citations
2006

β4 Integrin Amplifies ErbB2 Signaling to Promote Mammary Tumorigenesis

Guo, W., Pylayeva, Y., Pepe, A., Yoshioka, T., Muller, W. J., Inghirami, G. & Giancotti, F. G., Aug 4 2006, In : Cell. 126, 3, p. 489-502 14 p.

Research output: Contribution to journalArticle

331 Scopus citations
2007

Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity

Liao, M. J., Cheng, C. Z., Zhou, B., Zimonjic, D. B., Mani, S. A., Kaba, M., Gifford, A., Reinhardt, F., Popescu, N. C., Guo, W., Elinor, N. E., Lodish, H. F. & Weinberg, R. A., Sep 1 2007, In : Cancer Research. 67, 17, p. 8131-8138 8 p.

Research output: Contribution to journalArticle

139 Scopus citations
2008

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

Huangfu, D., Maehr, R., Guo, W., Eijkelenboom, A., Snitow, M., Chen, A. E. & Melton, D. A., Jul 1 2008, In : Nature biotechnology. 26, 7, p. 795-797 3 p.

Research output: Contribution to journalArticle

1187 Scopus citations

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

Huangfu, D., Osafune, K., Maehr, R., Guo, W., Eijkelenboom, A., Chen, S., Muhlestein, W. & Melton, D. A., Nov 1 2008, In : Nature biotechnology. 26, 11, p. 1269-1275 7 p.

Research output: Contribution to journalArticle

1043 Scopus citations

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

Mani, S. A., Guo, W., Liao, M. J., Eaton, E. N., Ayyanan, A., Zhou, A. Y., Brooks, M., Reinhard, F., Zhang, C. C., Shipitsin, M., Campbell, L. L., Polyak, K., Brisken, C., Yang, J. & Weinberg, R. A., May 16 2008, In : Cell. 133, 4, p. 704-715 12 p.

Research output: Contribution to journalArticle

5622 Scopus citations
2011

Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast

Scheel, C., Eaton, E. N., Li, S. H. J., Chaffer, C. L., Reinhardt, F., Kah, K. J., Bell, G., Guo, W., Rubin, J., Richardson, A. L. & Weinberg, R. A., Jun 10 2011, In : Cell. 145, 6, p. 926-940 15 p.

Research output: Contribution to journalArticle

570 Scopus citations
2012

Slug and Sox9 cooperatively determine the mammary stem cell state

Guo, W., Keckesova, Z., Donaher, J. L., Shibue, T., Tischler, V., Reinhardt, F., Itzkovitz, S., Noske, A., Zürrer-Härdi, U., Bell, G., Tam, W. L., Mani, S. A., Van Oudenaarden, A. & Weinberg, R. A., Mar 2 2012, In : Cell. 148, 5, p. 1015-1028 14 p.

Research output: Contribution to journalArticle

548 Scopus citations
2013

Protein Kinase C α Is a Central Signaling Node and Therapeutic Target for Breast Cancer Stem Cells

Tam, W. L., Lu, H., Buikhuisen, J., Soh, B. S., Lim, E., Reinhardt, F., Wu, Z. J., Krall, J. A., Bierie, B., Guo, W., Chen, X., Liu, X. S., Brown, M., Lim, B. & Weinberg, R. A., Sep 9 2013, In : Cancer Cell. 24, 3, p. 347-364 18 p.

Research output: Contribution to journalArticle

180 Scopus citations

Stability and prognostic value of Slug, Sox9 and Sox10 expression in breast cancers treated with neoadjuvant chemotherapy

Riemenschnitter, C., Teleki, I., Tischler, V., Guo, W. & Varga, Z., Jan 1 2013, In : SpringerPlus. 2, 1, 695.

Research output: Contribution to journalArticle

14 Scopus citations
2014

Concise review: Breast cancer stem cells: Regulatory networks, stem cell niches, and disease relevance

Guo, W., Ruth, L. & Gottesman, D. S., 2014, In : Stem Cells Translational Medicine. 3, 8, p. 942-948 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Evolving views of breast cancer stem cells and their differentiation states

Condiotti, R., Guo, W. & Ben-Porath, I., Jan 1 2014, In : Critical Reviews in Oncogenesis. 19, 5, p. 337-348 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Prolyl isomerase pin1 acts downstream of mir200c to promote cancer stem-like cell traits in breast cancer

Luo, M. L., Gong, C., Chen, C. H., Lee, D. Y., Hu, H., Huang, P., Yao, Y., Guo, W., Reinhardt, F., Wulf, G., Lieberman, J., Zhou, X. Z., Song, E. & Lu, K. P., Jul 1 2014, In : Cancer Research. 74, 13, p. 3603-3616 14 p.

Research output: Contribution to journalArticle

47 Scopus citations
2015

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment

Wang, P., Lin, M., Pedrosa, E., Hrabovsky, A., Zhang, Z., Guo, W., Lachman, H. M. & Zheng, D., Dec 2015, In : Molecular Autism. 6, 1, 48.

Research output: Contribution to journalArticle

60 Scopus citations

Differential expression of epithelial–mesenchymal transition and stem cell markers in intrinsic subtypes of breast cancer

Pomp, V., Leo, C., Mauracher, A., Korol, D., Guo, W. & Varga, Z., Oct 14 2015, In : Breast Cancer Research and Treatment. 154, 1, p. 45-55 11 p.

Research output: Contribution to journalArticle

19 Scopus citations
2016

Mammary-Stem-Cell-Based Somatic Mouse Models Reveal Breast Cancer Drivers Causing Cell Fate Dysregulation

Zhang, Z., Christin, J. R., Wang, C., Ge, K., Oktay, M. H. & Guo, W., Sep 20 2016, In : Cell Reports. 16, 12, p. 3146-3156 11 p.

Research output: Contribution to journalArticle

19 Scopus citations
2017

Lineage-Biased Stem Cells Maintain Estrogen-Receptor-Positive and -Negative Mouse Mammary Luminal Lineages

Wang, C., Christin, J. R., Oktay, M. H. & Guo, W., Mar 21 2017, In : Cell Reports. 18, 12, p. 2825-2835 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation

Donnelly, S. K., Cabrera, R., Mao, S. P. H., Christin, J. R., Wu, B., Guo, W., Bravo-Cordero, J. J., Condeelis, J. S., Segall, J. E. & Hodgson, L., Jan 1 2017, In : Journal of Cell Biology. 216, 12, p. 4331-4349 19 p.

Research output: Contribution to journalArticle

19 Scopus citations
2018

Histone Variant MacroH2A1 Plays an Isoform-Specific Role in Suppressing Epithelial-Mesenchymal Transition

Hodge, D. Q., Cui, J., Gamble, M. J. & Guo, W., Dec 1 2018, In : Scientific Reports. 8, 1, 841.

Research output: Contribution to journalArticle

2 Scopus citations

Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis

Mao, S. P. H., Park, M., Cabrera, R. M., Christin, J. R., Karagiannis, G. S., Oktay, M. H., Zaiss, D. M. W., Abrams, S. I., Guo, W., Condeelis, J. S., Kenny, P. A. & Segall, J. E., Oct 26 2018, In : Breast Cancer Research. 20, 1, 131.

Research output: Contribution to journalArticle

3 Scopus citations
2020

Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression

Wei, Q., Nakahara, F., Asada, N., Zhang, D., Gao, X., Xu, C., Alfieri, A., Brodin, N. P., Zimmerman, S. E., Mar, J. C., Guha, C., Guo, W. & Frenette, P. S., Jun 8 2020, In : Developmental cell. 53, 5, p. 503-513.e5

Research output: Contribution to journalArticle

Stem Cell Determinant SOX9 Promotes Lineage Plasticity and Progression in Basal-like Breast Cancer

Christin, J. R., Wang, C., Chung, C. Y., Liu, Y., Dravis, C., Tang, W., Oktay, M. H., Wahl, G. M. & Guo, W., Jun 9 2020, In : Cell Reports. 31, 10, 107742.

Research output: Contribution to journalArticle

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