• 3892 Citations
  • 22 h-Index
1974 …2020

Research output per year

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Publications

  • 3892 Citations
  • 22 h-Index
  • 30 Article
  • 3 Review article
  • 2 Comment/debate
  • 1 Short survey
2020

Comparisons and approaches of PREP programs at different stages of maturity: Challenges, best practices and benefits

Schwartz, N. B., Risner, L. E., Domowicz, M. & Freedman, V. H., 2020, In : Ethnicity and Disease. 30, 1, p. 55-64 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Competency-based assessment for the training of PhD students and early-career scientists

Verderame, M. F., Freedman, V. H., Kozlowski, L. M. & McCormack, W. T., May 31 2018, In : eLife. 7, e34801.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2002

Erratum: Use of IMiD3, a thalidomide analog, as an adjunct to therapy for experimental tuberculous meningitis (Antimicrobial Agents and Chemotherapy (2002) 46:6 (1887-1895))

Tsenova, L., Mangaliso, B., Muller, G., Chen, Y., Freedman, V. H., Stirling, D. & Kaplan, G., Jan 1 2002, In : Antimicrobial agents and chemotherapy. 46, 7, 1 p.

Research output: Contribution to journalComment/debate

Mycobacterial antigens exacerbate disease manifestations in Mycobacterium tuberculosis-infected mice

Moreira, A. L., Tsenova, L., Aman, M. H., Bekker, L. G., Freeman, S., Mangaliso, B., Schröder, U., Jagirdar, J., Rom, W. N., Tovey, M. G., Freedman, V. H. & Kaplan, G., 2002, In : Infection and immunity. 70, 4, p. 2100-2107 8 p.

Research output: Contribution to journalArticle

80 Scopus citations

Use of IMiD3, a thalidomide analog, as an adjunct to therapy for experimental tuberculous meningitis

Tsenova, L., Mangaliso, B., Muller, G., Chen, Y., Freedman, V. H., Stirling, D. & Kaplan, G., 2002, In : Antimicrobial agents and chemotherapy. 46, 6, p. 1887-1895 9 p.

Research output: Contribution to journalArticle

47 Scopus citations
2001

Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-α/β

Manca, C., Tsenova, L., Bergtold, A., Freeman, S., Tovey, M., Musser, J. M., Barry, C. E., Freedman, V. H. & Kaplan, G., May 8 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 10, p. 5752-5757 6 p.

Research output: Contribution to journalArticle

428 Scopus citations
2000

Human α-1-acid glycoprotein inhibits TNF production in the CNS of rabbits with meningitis: A report of preliminary observations

Moore, D. F., Tsenova, L., Corral, L., Freedman, V. H. & Kaplan, G., Jan 1 2000, In : Inflammation. 24, 3, p. 265-275 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
1999

How mycobacterium leprae infects peripheral nerves

Freedman, V. H., Weinstein, D. E. & Kaplan, G., Jan 1 1999, In : Leprosy Review. 70, 2, p. 136-139 4 p.

Research output: Contribution to journalComment/debate

Open Access
12 Scopus citations

Molecular mechanism of nerve infection in leprosy

Weinstein, D. E., Freedman, V. H. & Kaplan, G., Jan 1 1999, In : Trends in Microbiology. 7, 5, p. 185-186 2 p.

Research output: Contribution to journalShort survey

9 Scopus citations

Mycobacterium tuberculosis catalase and peroxidase activities and resistance to oxidative killing in human monocytes in vitro

Manca, C., Paul, S., Barry, C. E., Freedman, V. H. & Kaplan, G., Jan 1999, In : Infection and immunity. 67, 1, p. 74-79 6 p.

Research output: Contribution to journalArticle

Open Access
175 Scopus citations

Mycobacterium tuberculosis CDC1551 induces a more vigorous host response in vivo and in vitro, but is not more virulent than other clinical isolates

Manca, C., Tsenova, L., Barry, C. E., Bergtold, A., Freeman, S., Haslett, P. A. J., Musser, J. M., Freedman, V. H. & Kaplan, G., Jun 1 1999, In : Journal of Immunology. 162, 11, p. 6740-6746 7 p.

Research output: Contribution to journalArticle

237 Scopus citations
127 Scopus citations
1998

A combination of thalidomide plus antibiotics protects rabbits from mycobacterial meningitis-Associated death

Tsenova, L., Sokol, K., Freedman, V. H. & Kaplan, G., Jan 1 1998, In : Journal of Infectious Diseases. 177, 6, p. 1563-1572 10 p.

Research output: Contribution to journalArticle

Open Access
114 Scopus citations

Tuberculosis research comes of age

Kaplan, G., Freedman, V. H., Russell, D. & Colston, M. J., Aug 19 1998, In : Molecular Medicine Today. 4, 8, p. 330-333 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
1997

Effect of cytokine modulation by thalidomide on the granulomatous response in murine tuberculosis

Moreira, A. L., Tsenova-Berkova, L., Wang, J., Laochumroonvorapong, P., Freeman, S., Freedman, V. H. & Kaplan, G., Jan 1 1997, In : Tubercle and Lung Disease. 78, 1, p. 47-55 9 p.

Research output: Contribution to journalArticle

79 Scopus citations

Mycobacterial growth and sensitivity to H2O2 killing in human monocytes in vitro

Laochumroonvorapong, P., Paul, S., Manca, C., Freedman, V. H. & Kaplan, G., 1997, In : Infection and immunity. 65, 11, p. 4850-4857 8 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

Perforin, a cytotoxic molecule which mediates cell necrosis, is not required for the early control of mycobacterial infection in mice

Laochumroonvorapong, P., Wang, J., Liu, C. C., Ye, W., Moreira, A. L., Elkon, K. B., Freedman, V. H. & Kaplan, G., Jan 1 1997, In : Infection and Immunity. 65, 1, p. 127-132 6 p.

Research output: Contribution to journalArticle

124 Scopus citations

Sequestration of Mycobacterium tuberculosis in tight vacuoles in vivo in lung macrophages of mice infected by the respiratory route

Moreira, A. L., Wang, J., Tsenova-Berkova, L., Hellmann, W., Freedman, V. H. & Kaplan, G., 1997, In : Infection and immunity. 65, 1, p. 305-308 4 p.

Research output: Contribution to journalArticle

Open Access
41 Scopus citations

Thalidomide and thalidomide analogs reduce HIV type 1 replication in human macrophages in Vitro

Moreira, A. L., Corral, L. G., Ye, W., Johnson, B., Stirling, D., Muller, G. W., Freedman, V. H. & Kaplan, G., Jul 1 1997, In : AIDS Research and Human Retroviruses. 13, 10, p. 857-863 7 p.

Research output: Contribution to journalArticle

70 Scopus citations

The emerging role of thalidomide therapy in HIV-infected patients

Haslett, P., Freedman, V. H. & Kaplan, G., May 1 1997, In : Infections in Medicine. 14, 5, p. 393-398+405-406

Research output: Contribution to journalReview article

4 Scopus citations

The metabolic and immunologic effects of short-term thalidomide reatment of patients infected with the human immunodeficiency virus

Haslett, P., Hempstead, M., Seidman, C., Diakun, J., Vasquez, D., Freedman, V. H. & Kaplan, G., Aug 10 1997, In : AIDS Research and Human Retroviruses. 13, 12, p. 1047-1054 8 p.

Research output: Contribution to journalArticle

85 Scopus citations
1996

Thalidomide as an anti-TNF-α inhibitor: Implications for clinical use

Klausner, J. D., Freedman, V. H. & Kaplan, G., Dec 1996, In : Clinical Immunology and Immunopathology. 81, 3, p. 219-223 5 p.

Research output: Contribution to journalReview article

111 Scopus citations

The effect of thalidomide on the pathogenesis of human immunodeficiency virus type 1 and M. tuberculosis infection

Klausner, J. D., Makonkawkeyoon, S., Akarasewi, P., Nakata, K., Kasinrerk, W., Corral, L., Dewar, R. L., Clifford Lane, H., Freedman, V. H. & Kaplan, G., Jan 1 1996, In : Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 11, 3, p. 247-257 11 p.

Research output: Contribution to journalArticle

164 Scopus citations

The role of cytokines in the immune response to tuberculosis

Kaplan, G. & Freedman, V. H., Jan 1 1996, In : Research in Immunology. 147, 8-9, p. 565-572 8 p.

Research output: Contribution to journalArticle

46 Scopus citations
1989

A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms

Scallon, B. J., Scigliano, E., Freedman, V. H., Miedel, M. C., Pan, Y. C. E., Unkeless, J. C. & Kochan, J. P., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 13, p. 5079-5083 5 p.

Research output: Contribution to journalArticle

Open Access
94 Scopus citations
1988

Structure and function of human and murine receptors for IgG

Unkeless, J. C., Scigliano, E. & Freedman, V. H., 1988, In : Annual Review of Immunology. 6, p. 251-281 31 p.

Research output: Contribution to journalReview article

372 Scopus citations
1984

Bacillus calmette-guérin-activated murine macrophages kill syngeneic melanoma cells under strict anaerobic conditions

Freedman, V. H., Gorrell, T. E., Nathan, C. F., Copeland, C. S. & Silverstein, S. C., Jul 1 1984, In : Journal of Experimental Medicine. 160, 1, p. 94-107 14 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Failure to elicit activated macrophages in light ear and pale ear mutant mice after treatment with BCG

Freedman, V. H., Meisler, M. & Lepay, D., Jan 1 1984, In : Federation Proceedings. 43, 6, p. no. 2242

Research output: Contribution to journalArticle

2 Scopus citations
1982
11 Scopus citations
1980

Macrophages elicited with heat-killed bacillus Calmette-Guerin protect C57BL/6J mice against a syngeneic melanoma

Freedman, V. H., Calvelli, T. A., Silagi, S. & Silverstein, S. C., 1980, In : Journal of Experimental Medicine. 152, 3, p. 657-673 17 p.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations
1977

Growth of murine sarcoma virus-transformed rat kidney cells in nude mice: Absence of induction of host endogenous viruses

Bilello, J. A., Freedman, V. H. & Shin, S. I., Jun 1977, In : Journal of the National Cancer Institute. 58, 6, p. 1691-1694 4 p.

Research output: Contribution to journalArticle

7 Scopus citations
24 Scopus citations
1976

Enhanced anchorage independence and tumorigenicity of aneuploid Chinese hamster cells with nearly doubled chromosome complements

Klinger, H. P., Shin, S. & Freedman, V. H., Jan 1 1976, In : Cytogenetics and Cell Genetics. 17, 4, p. 185-199 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Mass production of animal cells in nude mice with retention of cell specific markers

Freedman, V. H., Brown, A. L., Klinger, H. P. & Shin, S. I., Mar 1 1976, In : Experimental Cell Research. 98, 1, p. 143-151 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
1975
Open Access
632 Scopus citations
1974

Cellular tumorigenicity in nude mice: Correlation with cell growth in semi-solid medium

Freedman, V. H. & Shin, S. I., Dec 1974, In : Cell. 3, 4, p. 355-359 5 p.

Research output: Contribution to journalArticle

691 Scopus citations