• 13969 Citations
  • 64 h-Index
1968 …2020

Research output per year

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Publications

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Review article
1977

Modulation of enzymic activity

Scrutton, M. C. & Schramm, V. L., 1977, In : Molecular aspects of medicine. 1, 4, p. 283-366 84 p.

Research output: Contribution to journalReview article

3 Scopus citations
1982

Metabolic regulation: could Mn2+ be involved?

Schramm, V. L., Oct 1982, In : Trends in Biochemical Sciences. 7, 10, p. 369-371 3 p.

Research output: Contribution to journalReview article

33 Scopus citations
1998

Enzymatic transition states and transition state analog design

Schramm, V. L., Sep 15 1998, In : Annual review of biochemistry. 67, p. 693-720 28 p.

Research output: Contribution to journalReview article

218 Scopus citations
2001

Atomic motion in enzymatic reaction coordinates

Schramm, V. L. & Shi, W., Dec 1 2001, In : Current Opinion in Structural Biology. 11, 6, p. 657-665 9 p.

Research output: Contribution to journalReview article

54 Scopus citations

Transition state variation in enzymatic reactions

Schramm, V. L., Oct 1 2001, In : Current Opinion in Chemical Biology. 5, 5, p. 556-564 9 p.

Research output: Contribution to journalReview article

25 Scopus citations
2002
79 Scopus citations
2003

Enzymatic transition state poise and transition state analogues

Schramm, V. L., Aug 1 2003, In : Accounts of Chemical Research. 36, 8, p. 588-596 9 p.

Research output: Contribution to journalReview article

104 Scopus citations

Imino-sugar-based nucleosides.

Schramm, V. L. & Tyler, P. C., 2003, In : Current topics in medicinal chemistry. 3, 5, p. 525-540 16 p.

Research output: Contribution to journalReview article

52 Scopus citations
2004

SIR2: The biochemical mehanism of NAD+-dependent protein deacetylation and ADP-ribosyl enzyme intermediates

Sauve, A. A. & Schramm, V. L., Apr 1 2004, In : Current medicinal chemistry. 11, 7, p. 807-826 20 p.

Research output: Contribution to journalReview article

63 Scopus citations
2005

Enzymatic transition states and transition state analogues

Schramm, V. L., Dec 1 2005, In : Current Opinion in Structural Biology. 15, 6, p. 604-613 10 p.

Research output: Contribution to journalReview article

82 Scopus citations

Transition states and inhibitors of the purine nucleoside phosphorylase family

Taylor Ringia, E. A. & Schramm, V. L., Dec 1 2005, In : Current Topics in Medicinal Chemistry. 5, 13, p. 1237-1258 22 p.

Research output: Contribution to journalReview article

37 Scopus citations
2006

The biochemistry of sirtuins

Sauve, A. A., Wolberger, C., Schramm, V. L. & Boeke, J. D., Jul 31 2006, In : Annual review of biochemistry. 75, p. 435-465 31 p.

Research output: Contribution to journalReview article

505 Scopus citations
2007

Binding isotope effects: boon and bane

Schramm, V. L., Oct 1 2007, In : Current Opinion in Chemical Biology. 11, 5, p. 529-536 8 p.

Research output: Contribution to journalReview article

61 Scopus citations
2009

Enzymatic transition states and dynamic motion in barrier crossing

Schwartz, S. D. & Schramm, V. L., Aug 2009, In : Nature Chemical Biology. 5, 8, p. 551-558 8 p.

Research output: Contribution to journalReview article

172 Scopus citations
2013

Transition-state inhibitors of purine salvage and other prospective enzyme targets in malaria

Ducati, R. G., Namanja-Magliano, H. A. & Schramm, V. L., Jul 1 2013, In : Future Medicinal Chemistry. 5, 11, p. 1341-1360 20 p.

Research output: Contribution to journalReview article

17 Scopus citations

Transition states, analogues, and drug development

Schramm, V. L., Jan 18 2013, In : ACS Chemical Biology. 8, 1, p. 71-81 11 p.

Research output: Contribution to journalReview article

80 Scopus citations
2018

Immucillins in Infectious Diseases

Evans, G. B., Tyler, P. C. & Schramm, V. L., Feb 9 2018, In : ACS Infectious Diseases. 4, 2, p. 107-117 11 p.

Research output: Contribution to journalReview article

9 Scopus citations

Promoting Vibrations and the Function of Enzymes. Emerging Theoretical and Experimental Convergence

Schramm, V. L. & Schwartz, S. D., Jun 19 2018, In : Biochemistry. 57, 24, p. 3299-3308 10 p.

Research output: Contribution to journalReview article

12 Scopus citations

The transition to magic bullets-transition state analogue drug design

Evans, G. B., Schramm, V. L. & Tyler, P. C., Jan 1 2018, In : MedChemComm. 9, 12, p. 1983-1993 11 p.

Research output: Contribution to journalReview article