• 562 Citations
  • 6 h-Index
20082015
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Fingerprint Dive into the research topics where Ujunwa C. Okoye-Okafor is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 21 Similar Profiles
Acute Myeloid Leukemia Medicine & Life Sciences
Isocitrate Dehydrogenase Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Homeobox Genes Medicine & Life Sciences
Gene Fusion Medicine & Life Sciences
Hematopoiesis Medicine & Life Sciences
B-Cell Lymphoma Medicine & Life Sciences
Embryonic Stem Cells Medicine & Life Sciences

Publications 2008 2015

  • 562 Citations
  • 6 h-Index
  • 6 Article
76 Citations (Scopus)

New IDH1 mutant inhibitors for treatment of acute myeloid leukemia

Okoye-Okafor, U. C., Bartholdy, B., Cartier, J., Gao, E. N., Pietrak, B., Rendina, A. R., Rominger, C., Quinn, C., Smallwood, A., Wiggall, K. J., Reif, A. J., Schmidt, S. J., Qi, H., Zhao, H., Joberty, G., Faelth-Savitski, M., Bantscheff, M., Drewes, G., Duraiswami, C., Brady, P. & 19 others, Groy, A., Narayanagari, S. R., Antony-Debre, I., Mitchell, K., Wang, H. R., Kao, Y. R., Christopeit, M., Carvajal, L., Barreyro, L., Paietta, E., Makishima, H., Will, B., Concha, N., Adams, N. D., Schwartz, B., McCabe, M. T., Maciejewski, J., Verma, A. & Steidl, U., Nov 1 2015, In : Nature Chemical Biology. 11, 11, p. 878-886 9 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Acute Myeloid Leukemia
Allosteric Site
Mutation
Cytosine
30 Citations (Scopus)

HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia

Bartholdy, B., Christopeit, M., Will, B., Mo, Y., Barreyro, L., Yu, Y., Bhagat, T. D., Okoye-Okafor, U. C., Todorova, T. I., Greally, J. M., Levine, R. L., Melnick, A., Verma, A. & Steidl, U., Mar 3 2014, In : Journal of Clinical Investigation. 124, 3, p. 1158-1167 10 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Epigenomics
Methylation
Myeloid Progenitor Cells
Megakaryocyte-Erythroid Progenitor Cells
58 Citations (Scopus)

Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment

Will, B., Vogler, T. O., Bartholdy, B., Garrett-Bakelman, F., Mayer, J., Barreyro, L., Pandolfi, A., Todorova, T. I., Okoye-Okafor, U. C., Stanley, R. F., Bhagat, T. D., Verma, A., Figueroa, M. E., Melnick, A., Roth, M. & Steidl, U., May 2013, In : Nature Immunology. 14, 5, p. 437-445 9 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem Cell Factor
Chromatin
Transcription Factors
Genes
30 Citations (Scopus)

H2.0-like Homeobox Regulates Early Hematopoiesis and Promotes Acute Myeloid Leukemia

Kawahara, M., Pandolfi, A., Bartholdy, B., Barreyro, L., Will, B., Roth, M., Okoye-Okafor, U. C., Todorova, T. I., Figueroa, M. E., Melnick, A., Mitsiades, C. S. & Steidl, U., Aug 14 2012, In : Cancer Cell. 22, 2, p. 194-208 15 p.

Research output: Contribution to journalArticle

Homeobox Genes
Hematopoiesis
Acute Myeloid Leukemia
Leukemia
Survival
348 Citations (Scopus)

MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers

Steidl, C., Shah, S. P., Woolcock, B. W., Rui, L., Kawahara, M., Farinha, P., Johnson, N. A., Zhao, Y., Telenius, A., Neriah, S. B., McPherson, A., Meissner, B., Okoye, U. C., Diepstra, A., Van Den Berg, A., Sun, M., Leung, G., Jones, S. J., Connors, J. M., Huntsman, D. G. & 7 others, Savage, K. J., Rimsza, L. M., Horsman, D. E., Staudt, L. M., Steidl, U., Marra, M. A. & Gascoyne, R. D., Mar 17 2011, In : Nature. 471, 7338, p. 377-383 7 p.

Research output: Contribution to journalArticle

Gene Fusion
B-Cell Lymphoma
Major Histocompatibility Complex
Hodgkin Disease
Programmed Cell Death 1 Receptor