• 11789 Citations
  • 53 h-Index
1980 …2020

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2020

Case Fatality Rate of Cancer Patients with COVID-19 in a New York Hospital System

Mehta, V., Goel, S., Kabarriti, R., Cole, D., Goldfinger, M., Acuna-Villaorduna, A., Pradhan, K., Thota, R., Reissman, S., Sparano, J. A., Gartrell, B. A., Smith, R. V., Ohri, N., Garg, M., Racine, A. D., Kalnicki, S., Perez-Soler, R., Halmos, B. & Verma, A., Jul 1 2020, In : Cancer discovery. 10, 7, p. 935-941 7 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Impact and diagnostic gaps of comprehensive genomic profiling in real-world clinical practice

Singh, A. P., Shum, E., Rajdev, L., Cheng, H., Goel, S., Perez-Soler, R. & Halmos, B., May 2020, In : Cancers. 12, 5, 1156.

Research output: Contribution to journalArticle

Open Access

Survival Disparities in Black Patients With EGFR-mutated Non–small-cell Lung Cancer

Cheng, H., Hosgood, H. D., Deng, L., Ye, K., Su, C., Sharma, J., Yang, Y., Halmos, B. & Perez-Soler, R., Mar 2020, In : Clinical lung cancer. 21, 2, p. 177-185 9 p.

Research output: Contribution to journalArticle

2019
1 Scopus citations
2018

Nanoparticle albumin bound-paclitaxel for treatment of advanced non-small cell lung cancer: an evaluation of the clinical evidence

Adrianzen Herrera, D., Ashai, N., Perez-Soler, R. & Cheng, H., Jan 1 2018, (Accepted/In press) In : Expert Opinion on Pharmacotherapy.

Research output: Contribution to journalArticle

7 Scopus citations
1 Scopus citations

Wide expression and significance of alternative immune checkpoint molecules, B7x and HHLA2, in PD-L1–negative human lung cancers

Cheng, H., Borczuk, A., Janakiram, M., Ren, X., Lin, J., Assal, A., Halmos, B., Perez-Soler, R. & Zang, X., Apr 15 2018, In : Clinical Cancer Research. 24, 8, p. 1954-1964 11 p.

Research output: Contribution to journalArticle

19 Scopus citations
40 Scopus citations

HHLA2, a new immune checkpoint member of the B7 family, is widely expressed in human lung cancer and associated with EGFR mutational status

Cheng, H., Janakiram, M., Borczuk, A., Lin, J., Qiu, W., Liu, H., Chinai, J. M., Halmos, B., Perez-Soler, R. & Zang, X., Feb 1 2017, In : Clinical Cancer Research. 23, 3, p. 825-832 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Randomized Phase 2 Trial of Pharmacodynamic Separation of Pemetrexed and Intercalated Erlotinib Versus Pemetrexed Alone for Advanced Nonsquamous, Non–small-cell Lung Cancer

Li, T., Piperdi, B., Walsh, W. V., Kim, M., Beckett, L. A., Gucalp, R., Haigentz, M., Bathini, V. G., Wen, H., Zhou, K., Pasquinelli, P. B., Gajavelli, S., Sreedhara, M., Xie, X., Lara, P. N., Gandara, D. R. & Perez-Soler, R., Jan 1 2017, In : Clinical lung cancer. 18, 1, p. 60-67 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

TRIB2 contributes to cisplatin resistance in small cell lung cancer

Liang, Y., Yu, D., Perez-Soler, R., Klostergaard, J. & Zou, Y., 2017, In : Oncotarget. 8, 65, p. 109596-109608 13 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Associations of insulin and IGFBP-3 with lung cancer susceptibility in current smokers

Ho, G. Y. F., Zheng, S. L., Cushman, M., Perez-Soler, R., Kim, M., Xue, X., Wang, T., Schlecht, N. F., Tinker, L., Rohan, T. E., Wassertheil-Smoller, S., Wallace, R., Chen, C., Xu, J. & Yu, H., 2016, In : Journal of the National Cancer Institute. 108, 7, djw012.

Research output: Contribution to journalArticle

14 Scopus citations

Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells

Cheng, H., Zhang, Z., Rodriguez-Barrueco, R. R., Borczuk, A., Liu, H., Yu, J., Silva, J. M., Cheng, S. K., Perez-Soler, R. & Halmos, B., May 17 2016, In : Oncotarget. 7, 20, p. 28976-28988 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Immune-modulation by epidermal growth factor receptor inhibitors: Implication on anti-tumor immunity in lung cancer

Im, J. S., Herrmann, A. C., Bernatchez, C., Haymaker, C., Molldrem, J. J., Hong, W. K. & Perez-Soler, R., Jul 2016, In : PloS one. 11, 7, e0160004.

Research output: Contribution to journalArticle

12 Scopus citations

Medical Treatment in Elderly Patients with Non-Small Cell Lung Cancer

Bakirhan, K., Sharma, J. N., Perez-Soler, R. & Cheng, H., Mar 1 2016, In : Current Treatment Options in Oncology. 17, 3, 13.

Research output: Contribution to journalArticle

7 Scopus citations

Toxicity and Pharmacokinetic Studies of Aerosolized Clinical Grade Azacitidine

Qiu, X., Liang, Y., Sellers, R. S., Perez-Soler, R. & Zou, Y., May 1 2016, In : Clinical lung cancer. 17, 3, p. 214-222.e1

Research output: Contribution to journalArticle

1 Scopus citations
2015

Discovery of autophagy inhibitors with antiproliferative activity in lung and pancreatic cancer cells

Nordstrøm, L. U., Sironi, J., Aranda, E., Maisonet, J., Perez-Soler, R., Wu, P. & Schwartz, E. L., Feb 12 2015, In : ACS Medicinal Chemistry Letters. 6, 2, p. 134-139 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
13 Scopus citations

RICTOR amplification defines a novel subset of patients with lung cancer who may benefit from treatment with mTORC1/2 inhibitors

Cheng, H., Zou, Y., Ross, J. S., Wang, K., Liu, X., Halmos, B., Ali, S. M., Liu, H., Verma, A., Montagna, C., Chachoua, A., Goel, S., Schwartz, E. L., Zhu, C., Shan, J., Yu, Y., Gritsman, K., Yelensky, R., Lipson, D., Otto, G. & 5 others, Hawryluk, M., Stephens, P. J., Miller, V. A., Piperdi, B. & Perez-Soler, R., Dec 2015, In : Cancer discovery. 5, 12, p. 1262-1270 9 p.

Research output: Contribution to journalArticle

50 Scopus citations
2014

Aerosol azacytidine inhibits orthotopic lung cancers in mice through its DNA demethylation and gene reactivation effects

Qiu, X., Liang, Y., Sellers, R. S., Perez-Soler, R. & Zou, Y., Oct 27 2014, In : PloS one. 9, 10, e109874.

Research output: Contribution to journalArticle

7 Scopus citations
2013

Talactoferrin alfa versus placebo in patients with refractory advanced non-small-cell lung cancer (FORTIS-M trial)

Ramalingam, S., Crawford, J., Chang, A., Manegold, C., Perez-Soler, R., Douillard, J. Y., Thatcher, N., Barlesi, F., Owonikoko, T., Wang, Y., Pultar, P., Zhu, J., Malik, R., Malik Giaccone, R., Della-Fiorentina, S., Begbie, S., Jennens, R., Dass, J., Pittman, K., Ivanova, N. & 173 others, Koynova, T., Petrov, P., Tomova, A., Tzekova, V., Couture, F., Hirsh, V., Burkes, R., Sangha, R., Ambrus, M., Janaskova, T., Musil, J., Novotny, J., Zatloukal, P., Jakesova, J., Klenha, K., Roubec, J., Vanasek, J., Fayette, J., Barlesi, F., Bennouna-Louridi, J., Chouaid, C., Mazières, J., Vallerand, H., Robinet, G., Souquet, P. J., Spaeth, D., Schott, R., Lena, H., Martinet, Y., Kouri, C. E., Baize, N., Scherpereel, A., Molinier, O., Fuchs, F., Josten, K. M., Manegold, C., Marschner, N., Schneller, F., Overbeck, T., Thomas, M., von Pawel, J., Reck Schuette, M., Hagen, V., Schneider, C. P., Georgoulias, V., Varthalitis, I., Zarogoulidis, K., Syrigos, K., Papandreou, C., Bocskei, C., Csanky, E., Juhasz, E., Losonczy, G., Mark, Z., Molnar, I., Papai-Szekely, Z., Tehenes, S., Vinkler, I., Almel, S., Bakshi, A., Bondarde, S., Maru, A., Pathak, A., Pedapenki, R. M., Prasad, K., Prasad, S. V. S. S., Kilara, N., Gorijavolu, D., Deshmukh, C. D., John, S., Sharma, L. M., Amoroso, D., Bajetta, E., Bidoli, P., Bonetti, A., De Marinis, F., Maio, M., Passalacqua, R., Cascinu, S., Bearz, A., Bitina, M., Brize, A., Purkalne, G., Skrodele, M., Baba, A. A., Ratnavelu, K., Saw, M. H., Samson-Fernando, M. C., Ladrera, G. E., Jassem, J., Koralewski, P., Sikorska, L., Serwatowski, P., Krzakowski, M., Cebotaru, C., Filip, D., Ganea-Motan, D. E., Ianuli, C. H., Manolescu, I. G., Udrea, A., Burdaeva, O., Byakhov, M., Filippov, A., Lazarev, S., Mosin, I., Orlov, S., Udovitsa, D., Khorinko, A., Protsenko, S., Chang, A., Lim, H. L., Tan, Y. O., Tan, E. H., Bastus Piulats, R., Garcia-Foncillas, J., Valdivia, J., de Castro, J., Domine Gomez, M., Kim, S. W., Lee, J. S., Kim, H. K., Lee, J. S., Shin, S. W., Kim, D. W., Kim, Y. C., Park, K. C., Chang, C. S., Chang, G. C., Goan, Y. G., Su, W. C., Tsai, C. M., Kuo, H. P., Benekli, M., Demir, G., Gokmen, E., Sevinc, A., Crawford, J., Giaccone, G., Haigentz, M., Owonikoko, T., Agarwal, M., Pandit, S., Araujo, R., Vrindavanam, N., Bonomi, P., Berg, A., Wade, J., Bloom, R., Amin, B., Camidge, R., Hill, D., Rarick, M., Flynn, P., Klein, L., Lo Russo, K., Neubauer, M., Richards, P., Ruxer, R., Savin, M., Weckstein, D., Rosenberg, R., Whittaker, T., Richards Berry, D., Ottensmeier, C., Dangoor, A., Steele, N., Summers, Y., Rankin, E., Rowley, K., Giridharan, S., Kristeleit, H., Humber, C. & Taylor, P., Nov 2013, In : Annals of Oncology. 24, 11, p. 2875-2880 6 p., mdt371.

Research output: Contribution to journalArticle

33 Scopus citations
75 Scopus citations
2012

Phase-I/II study of bortezomib in combination with carboplatin and bevacizumab as first-line therapy in patients with advanced non-small-cell lung cancer

Piperdi, B., Walsh, W. V., Bradley, K., Zhou, Z., Bathini, V., Hanrahan-Boshes, M., Hutchinson, L. & Perez-Soler, R., Jun 2012, In : Journal of Thoracic Oncology. 7, 6, p. 1032-1040 9 p.

Research output: Contribution to journalArticle

22 Scopus citations
2011

Both gene amplification and allelic loss occur at 14q13.3 in lung cancer

Harris, T., Pan, Q., Sironi, J., Lutz, D., Tian, J., Sapkar, J., Perez-Soler, R., Keller, S. & Locker, J., Feb 15 2011, In : Clinical Cancer Research. 17, 4, p. 690-699 10 p.

Research output: Contribution to journalArticle

30 Scopus citations
53 Scopus citations

The phosphatase inhibitor menadione (Vitamin K3) protects cells from EGFR inhibition by erlotinib and cetuximab

Perez-Soler, R., Zou, Y., Li, T. & Ling, Y. H., Nov 1 2011, In : Clinical Cancer Research. 17, 21, p. 6766-6777 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Treatment of non-small-cell lung cancer with erlotinib or gefitinib

Cataldo, V. D., Gibbons, D. L., Pérez-Soler, R. & Quintás-Cardama, A., Mar 10 2011, In : New England Journal of Medicine. 364, 10, p. 947-955 9 p.

Research output: Contribution to journalArticle

290 Scopus citations
2010

Intratracheally administered 5-azacytidine is effective against orthotopic human lung cancer xenograft models and devoid of important systemic toxicity

Mahesh, S., Saxena, A., Qiu, X., Perez-Soler, R. & Zou, Y., Nov 1 2010, In : Clinical lung cancer. 11, 6, p. 405-411 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
42 Scopus citations
2009
39 Scopus citations
37 Scopus citations
2008
46 Scopus citations

PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab

Jhawer, M., Goel, S., Wilson, A. J., Montagna, C., Ling, Y. H., Byun, D. S., Nasser, S., Arango, D., Shin, J., Klampfer, L., Augenlicht, L. H., Soler, R. P. & Mariadason, J. M., Mar 15 2008, In : Cancer research. 68, 6, p. 1953-1961 9 p.

Research output: Contribution to journalArticle

387 Scopus citations
15 Scopus citations
2007

Clinical research of EGFR inhibitors and related dermatologic toxicities.

Perez-Soler, R. & Van Cutsem, E., Oct 2007, In : Oncology (Williston Park, N.Y.). 21, 11 Suppl 5, p. 10-16 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Erlotinib: Recent clinical results and ongoing studies in non-small cell lung cancer

Perez-Soler, R., Aug 1 2007, In : Clinical Cancer Research. 13, 15, p. 4589s-4592s

Research output: Contribution to journalArticle

12 Scopus citations
68 Scopus citations

Novel agents in the treatment of lung cancer: Fourth Cambridge conference

Lynch, T. J., Bonomi, P. D., Butts, C., Davies, A. M., Engelman, J., Govindan, R., Herbst, R. S., Heymach, J. V., Johnson, B. E., Martins, R. G., Perez-Soler, R., Riely, G. J., Sandler, A. B., Sequist, L. V., Socinski, M. A., Wong, K. K. & Hart, C. S., Aug 1 2007, In : Clinical Cancer Research. 13, 15, p. 4583s-4588s

Research output: Contribution to journalArticle

6 Scopus citations

p53 aerosol formulationwith low toxicity and high efficiency for early lung cancer treatment

Zou, Y., Tornos, C., Qiu, X., Lia, M. & Perez-Soler, R., Aug 15 2007, In : Clinical Cancer Research. 13, 16, p. 4900-4908 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Phase I study of aerosolized SLIT cisplatin in the treatment of patients with carcinoma of the lung

Wittgen, B. P. H., Kunst, P. W. A., Van Der Born, K., Van Wijk, A. W., Perkins, W., Pilkiewicz, F. G., Perez-Soler, R., Nicholson, S., Peters, G. J. & Postmus, P. E., Apr 15 2007, In : Clinical Cancer Research. 13, 8, p. 2414-2421 8 p.

Research output: Contribution to journalArticle

108 Scopus citations

Schedule-dependent cytotoxic synergism of pemetrexed and erlotinib in human non-small cell lung cancer cells

Li, T., Ling, Y. H., Goldman, I. D. & Perez-Soler, R., Jun 1 2007, In : Clinical Cancer Research. 13, 11, p. 3413-3422 10 p.

Research output: Contribution to journalArticle

169 Scopus citations
24 Scopus citations

Targeting protein translation in human non-small cell lung cancer via combined MEK and mammalian target of rapamycin suppression

Legrier, M. E., Yang, C. P. H., Yan, H. G., Lopez-Barcons, L., Keller, S. M., Pérez-Soler, R., Horwitz, S. B. & McDaid, H. M., Dec 1 2007, In : Cancer Research. 67, 23, p. 11300-11308 9 p.

Research output: Contribution to journalArticle

76 Scopus citations
2006
91 Scopus citations
2005

Enhanced sensitivity to the HER1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib hydrochloride in chemotherapy-resistant tumor cell lines

Dai, Q., Ling, Y. H., Lia, M., Zou, Y. Y., Kroog, G., Iwata, K. K. & Perez-Soler, R., Feb 15 2005, In : Clinical Cancer Research. 11, 4, p. 1572-1578 7 p.

Research output: Contribution to journalArticle

77 Scopus citations

Enhancement of the therapeutic efficacy of taxol by the mitogen-activated protein kinase kinase inhibitor CI-1040 in nude mice bearing human heterotransplants

McDaid, H. M., Lopez-Barcons, L., Grossman, A., Lia, M., Keller, S., Pérez-Soler, R. & Horwitz, S. B., Apr 1 2005, In : Cancer Research. 65, 7, p. 2854-2860 7 p.

Research output: Contribution to journalArticle

77 Scopus citations

Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesothelioma

Lu, C., Perez-Soler, R., Piperdi, B., Walsh, G. L., Swisher, S. G., Smythe, W. R., Shin, H. J., Ro, J. Y., Feng, L., Truong, M., Yalamanchili, A., Lopez-Berestein, G., Hong, W. K., Khokhar, A. R. & Shin, D. M., Dec 1 2005, In : Journal of Clinical Oncology. 23, 15, p. 3495-3501 7 p.

Research output: Contribution to journalArticle

63 Scopus citations
2004

A Review of Small-Molecule Epidermal Growth Factor Receptor-Specific Tyrosine Kinase Inhibitors in Development for Non-Small Cell Lung Cancer

Glover, K. Y., Perez-Soler, R. & Papadimitradopoulou, V. A., Feb 2004, In : Seminars in Oncology. 31, 1 SUPPL. 1, p. 83-92 10 p.

Research output: Contribution to journalArticle

21 Scopus citations