• 11789 Citations
  • 53 h-Index
1980 …2020

Research output per year

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Publications

2020

Case Fatality Rate of Cancer Patients with COVID-19 in a New York Hospital System

Mehta, V., Goel, S., Kabarriti, R., Cole, D., Goldfinger, M., Acuna-Villaorduna, A., Pradhan, K., Thota, R., Reissman, S., Sparano, J. A., Gartrell, B. A., Smith, R. V., Ohri, N., Garg, M., Racine, A. D., Kalnicki, S., Perez-Soler, R., Halmos, B. & Verma, A., Jul 1 2020, In : Cancer discovery. 10, 7, p. 935-941 7 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Impact and diagnostic gaps of comprehensive genomic profiling in real-world clinical practice

Singh, A. P., Shum, E., Rajdev, L., Cheng, H., Goel, S., Perez-Soler, R. & Halmos, B., May 2020, In : Cancers. 12, 5, 1156.

Research output: Contribution to journalArticle

Open Access

Survival Disparities in Black Patients With EGFR-mutated Non–small-cell Lung Cancer

Cheng, H., Hosgood, H. D., Deng, L., Ye, K., Su, C., Sharma, J., Yang, Y., Halmos, B. & Perez-Soler, R., Mar 2020, In : Clinical lung cancer. 21, 2, p. 177-185 9 p.

Research output: Contribution to journalArticle

2019
1 Scopus citations
2018

Leptomeningeal metastases in non-small-cell lung cancer

Cheng, H. & Perez-Soler, R., Jan 1 2018, In : The Lancet Oncology. 19, 1, p. e43-e55

Research output: Contribution to journalReview article

47 Scopus citations

Mouse models in squamous cell lung cancer: impact for drug discovery

Singh, A. P., Adrianzen Herrera, D., Zhang, Y., Perez-Soler, R. & Cheng, H., Apr 3 2018, In : Expert Opinion on Drug Discovery. 13, 4, p. 347-358 12 p.

Research output: Contribution to journalReview article

2 Scopus citations

Nanoparticle albumin bound-paclitaxel for treatment of advanced non-small cell lung cancer: an evaluation of the clinical evidence

Adrianzen Herrera, D., Ashai, N., Perez-Soler, R. & Cheng, H., Jan 1 2018, (Accepted/In press) In : Expert Opinion on Pharmacotherapy.

Research output: Contribution to journalArticle

7 Scopus citations
1 Scopus citations

Wide expression and significance of alternative immune checkpoint molecules, B7x and HHLA2, in PD-L1–negative human lung cancers

Cheng, H., Borczuk, A., Janakiram, M., Ren, X., Lin, J., Assal, A., Halmos, B., Perez-Soler, R. & Zang, X., Apr 15 2018, In : Clinical Cancer Research. 24, 8, p. 1954-1964 11 p.

Research output: Contribution to journalArticle

19 Scopus citations
40 Scopus citations

Emerging treatment using tubulin inhibitors in advanced non-small cell lung cancer

Hardin, C., Shum, E., Singh, A., Perez-Soler, R. & Cheng, H., May 3 2017, In : Expert Opinion on Pharmacotherapy. 18, 7, p. 701-716 16 p.

Research output: Contribution to journalReview article

14 Scopus citations

HHLA2, a new immune checkpoint member of the B7 family, is widely expressed in human lung cancer and associated with EGFR mutational status

Cheng, H., Janakiram, M., Borczuk, A., Lin, J., Qiu, W., Liu, H., Chinai, J. M., Halmos, B., Perez-Soler, R. & Zang, X., Feb 1 2017, In : Clinical Cancer Research. 23, 3, p. 825-832 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Investigational therapies for squamous cell lung cancer: from animal studies to phase II trials

Shum, E., Wang, F., Kim, S., Perez-Soler, R. & Cheng, H., Apr 3 2017, In : Expert Opinion on Investigational Drugs. 26, 4, p. 415-426 12 p.

Research output: Contribution to journalReview article

2 Scopus citations

Pax5 Re-expression in H460 cells treated with the combination of demethylating agent and histone deacetylase inhibitor is associated with the enhancement of P53 binding to Pax5 promoter region

Liang, Y., Zeng, J., Jelicks, L. A., Ma, S., Liu, J., Mei, J., Perez-Soler, R. & Zou, Y., Feb 1 2017, In : Current Cancer Drug Targets. 17, 2, p. 169-176 8 p.

Research output: Contribution to journalReview article

1 Scopus citations

Randomized Phase 2 Trial of Pharmacodynamic Separation of Pemetrexed and Intercalated Erlotinib Versus Pemetrexed Alone for Advanced Nonsquamous, Non–small-cell Lung Cancer

Li, T., Piperdi, B., Walsh, W. V., Kim, M., Beckett, L. A., Gucalp, R., Haigentz, M., Bathini, V. G., Wen, H., Zhou, K., Pasquinelli, P. B., Gajavelli, S., Sreedhara, M., Xie, X., Lara, P. N., Gandara, D. R. & Perez-Soler, R., Jan 1 2017, In : Clinical lung cancer. 18, 1, p. 60-67 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Speaking the same language: a feasibility trial for a novel visual communication tool for oncologist-patient treatment discussions

Zanartu, C. P., Camacho, F. J., Nevadunski, N. S., Martin, B., Kornblum, N., Chuy, J. & Perez-Soler, R., Jul 1 2017, In : Psycho-Oncology. 26, 7, p. 1050-1052 3 p.

Research output: Contribution to journalLetter

The Use of Antiangiogenic Agents for Lung Cancer in Elderly Patients: An Expert Panel Discussion Synopsis

Socinski, M. A., Chaft, J. E., Levy, B., Riely, G. J., Langer, C. J., Perez-Soler, R., Middleton, D. L., Gracie-King, L. & Healy, L. M., May 2017, In : Clinical lung cancer. 18, 3, p. 255-258 4 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

TRIB2 contributes to cisplatin resistance in small cell lung cancer

Liang, Y., Yu, D., Perez-Soler, R., Klostergaard, J. & Zou, Y., 2017, In : Oncotarget. 8, 65, p. 109596-109608 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Use of liposomes as carriers of lipophilic antitumor agents

Perez-Soler, R., Khokhar, A. R., Priebe, W. & Krakoff, I. H., Jan 1 2017, Liposomes in Drug Delivery. CRC Press, p. 1-9 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Associations of insulin and IGFBP-3 with lung cancer susceptibility in current smokers

Ho, G. Y. F., Zheng, S. L., Cushman, M., Perez-Soler, R., Kim, M., Xue, X., Wang, T., Schlecht, N. F., Tinker, L., Rohan, T. E., Wassertheil-Smoller, S., Wallace, R., Chen, C., Xu, J. & Yu, H., 2016, In : Journal of the National Cancer Institute. 108, 7, djw012.

Research output: Contribution to journalArticle

14 Scopus citations

Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells

Cheng, H., Zhang, Z., Rodriguez-Barrueco, R. R., Borczuk, A., Liu, H., Yu, J., Silva, J. M., Cheng, S. K., Perez-Soler, R. & Halmos, B., May 17 2016, In : Oncotarget. 7, 20, p. 28976-28988 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Immune-modulation by epidermal growth factor receptor inhibitors: Implication on anti-tumor immunity in lung cancer

Im, J. S., Herrmann, A. C., Bernatchez, C., Haymaker, C., Molldrem, J. J., Hong, W. K. & Perez-Soler, R., Jul 2016, In : PloS one. 11, 7, e0160004.

Research output: Contribution to journalArticle

12 Scopus citations

Medical Treatment in Elderly Patients with Non-Small Cell Lung Cancer

Bakirhan, K., Sharma, J. N., Perez-Soler, R. & Cheng, H., Mar 1 2016, In : Current Treatment Options in Oncology. 17, 3, 13.

Research output: Contribution to journalArticle

7 Scopus citations

Toxicity and Pharmacokinetic Studies of Aerosolized Clinical Grade Azacitidine

Qiu, X., Liang, Y., Sellers, R. S., Perez-Soler, R. & Zou, Y., May 1 2016, In : Clinical lung cancer. 17, 3, p. 214-222.e1

Research output: Contribution to journalArticle

1 Scopus citations
2015

Discovery of autophagy inhibitors with antiproliferative activity in lung and pancreatic cancer cells

Nordstrøm, L. U., Sironi, J., Aranda, E., Maisonet, J., Perez-Soler, R., Wu, P. & Schwartz, E. L., Feb 12 2015, In : ACS Medicinal Chemistry Letters. 6, 2, p. 134-139 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Emerging drugs for squamous cell lung cancer

Cheng, H., Shcherba, M., Kandavelou, K., Liang, Y., Liu, H. & Perez-Soler, R., Mar 1 2015, In : Expert Opinion on Emerging Drugs. 20, 1, p. 149-160 12 p.

Research output: Contribution to journalReview article

12 Scopus citations

Emerging treatment for advanced lung cancer with EGFR mutation

Inal, C., Yilmaz, E., Piperdi, B., Perez-Soler, R. & Cheng, H., Oct 2 2015, In : Expert Opinion on Emerging Drugs. 20, 4, p. 597-612 16 p.

Research output: Contribution to journalReview article

11 Scopus citations

In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs

Tefferi, A., Kantarjian, H., Rajkumar, S. V., Baker, L. H., Abkowitz, J. L., Adamson, J. W., Advani, R. H., Allison, J., Antman, K. H., Bast, R. C., Bennett, J. M., Benz, E. J., Berliner, N., Bertino, J., Bhatia, R., Bhatia, S., Bhojwani, D., Blanke, C. D., Bloomfield, C. D., Bosserman, L. & 95 others, Broxmeyer, H. E., Byrd, J. C., Cabanillas, F., Canellos, G. P., Chabner, B. A., Chanan-Khan, A., Cheson, B., Clarkson, B., Cohn, S. L., Colon-Otero, G., Cortes, J., Coutre, S., Cristofanilli, M., Curran, W. J., Daley, G. Q., Deangelo, D. J., Deeg, H. J., Einhorn, L. H., Erba, H. P., Esteva, F. J., Estey, E., Fidler, I. J., Foran, J., Forman, S., Freireich, E., Fuchs, C., George, J. N., Gertz, M. A., Giralt, S., Golomb, H., Greenberg, P., Gutterman, J., Handin, R. I., Hellman, S., Hoff, P. M., Hoffman, R., Hong, W. K., Horowitz, M., Hortobagyi, G. N., Hudis, C., Issa, J. P., Johnson, B. E., Kantoff, P. W., Kaushansky, K., Khayat, D., Khuri, F. R., Kipps, T. J., Kripke, M., Kyle, R. A., Larson, R. A., Lawrence, T. S., Levine, R., Link, M. P., Lippman, S. M., Lonial, S., Lyman, G. H., Markman, M., Mendelsohn, J., Meropol, N. J., Messinger, Y., Mulvey, T. M., O'Brien, S., Perez-Soler, R., Pollock, R., Prchal, J., Press, O., Radich, J., Rai, K., Rosenberg, S. A., Rowe, J. M., Rugo, H., Runowicz, C. D., Sandmaier, B. M., Saven, A., Schafer, A. I., Schiffer, C., Sekeres, M. A., Silver, R. T., Siu, L. L., Steensma, D. P., Stewart, F. M., Stock, W., Stone, R., Storb, R., Strong, L. C., Tallman, M. S., Thompson, M., Ueno, N. T., Van Etten, R. A., Vose, J. M., Wiernik, P. H., Winer, E. P., Younes, A., Zelenetz, A. D. & Lemaistre, C. A., Aug 1 2015, In : Mayo Clinic Proceedings. 90, 8, p. 996-1000 5 p.

Research output: Contribution to journalShort survey

104 Scopus citations
13 Scopus citations

RICTOR amplification defines a novel subset of patients with lung cancer who may benefit from treatment with mTORC1/2 inhibitors

Cheng, H., Zou, Y., Ross, J. S., Wang, K., Liu, X., Halmos, B., Ali, S. M., Liu, H., Verma, A., Montagna, C., Chachoua, A., Goel, S., Schwartz, E. L., Zhu, C., Shan, J., Yu, Y., Gritsman, K., Yelensky, R., Lipson, D., Otto, G. & 5 others, Hawryluk, M., Stephens, P. J., Miller, V. A., Piperdi, B. & Perez-Soler, R., Dec 2015, In : Cancer discovery. 5, 12, p. 1262-1270 9 p.

Research output: Contribution to journalArticle

50 Scopus citations
2014

Aerosol azacytidine inhibits orthotopic lung cancers in mice through its DNA demethylation and gene reactivation effects

Qiu, X., Liang, Y., Sellers, R. S., Perez-Soler, R. & Zou, Y., Oct 27 2014, In : PloS one. 9, 10, e109874.

Research output: Contribution to journalArticle

7 Scopus citations

Cell cycle inhibitors for the treatment of NSCLC

Shcherba, M., Liang, Y., Fernandes, D., Perez-Soler, R. & Cheng, H., May 2014, In : Expert Opinion on Pharmacotherapy. 15, 7, p. 991-1004 14 p.

Research output: Contribution to journalReview article

11 Scopus citations

Targeting angiogenesis in squamous non-small cell lung cancer

Piperdi, B., Merla, A. & Perez-Soler, R., Mar 2014, In : Drugs. 74, 4, p. 403-413 11 p.

Research output: Contribution to journalReview article

37 Scopus citations

Talactoferrin alfa versus placebo in patients with refractory advanced non-small-cell lung cancer (FORTIS-M trial)

Ramalingam, S., Crawford, J., Chang, A., Manegold, C., Perez-Soler, R., Douillard, J. Y., Thatcher, N., Barlesi, F., Owonikoko, T., Wang, Y., Pultar, P., Zhu, J., Malik, R., Malik Giaccone, R., Della-Fiorentina, S., Begbie, S., Jennens, R., Dass, J., Pittman, K., Ivanova, N. & 173 others, Koynova, T., Petrov, P., Tomova, A., Tzekova, V., Couture, F., Hirsh, V., Burkes, R., Sangha, R., Ambrus, M., Janaskova, T., Musil, J., Novotny, J., Zatloukal, P., Jakesova, J., Klenha, K., Roubec, J., Vanasek, J., Fayette, J., Barlesi, F., Bennouna-Louridi, J., Chouaid, C., Mazières, J., Vallerand, H., Robinet, G., Souquet, P. J., Spaeth, D., Schott, R., Lena, H., Martinet, Y., Kouri, C. E., Baize, N., Scherpereel, A., Molinier, O., Fuchs, F., Josten, K. M., Manegold, C., Marschner, N., Schneller, F., Overbeck, T., Thomas, M., von Pawel, J., Reck Schuette, M., Hagen, V., Schneider, C. P., Georgoulias, V., Varthalitis, I., Zarogoulidis, K., Syrigos, K., Papandreou, C., Bocskei, C., Csanky, E., Juhasz, E., Losonczy, G., Mark, Z., Molnar, I., Papai-Szekely, Z., Tehenes, S., Vinkler, I., Almel, S., Bakshi, A., Bondarde, S., Maru, A., Pathak, A., Pedapenki, R. M., Prasad, K., Prasad, S. V. S. S., Kilara, N., Gorijavolu, D., Deshmukh, C. D., John, S., Sharma, L. M., Amoroso, D., Bajetta, E., Bidoli, P., Bonetti, A., De Marinis, F., Maio, M., Passalacqua, R., Cascinu, S., Bearz, A., Bitina, M., Brize, A., Purkalne, G., Skrodele, M., Baba, A. A., Ratnavelu, K., Saw, M. H., Samson-Fernando, M. C., Ladrera, G. E., Jassem, J., Koralewski, P., Sikorska, L., Serwatowski, P., Krzakowski, M., Cebotaru, C., Filip, D., Ganea-Motan, D. E., Ianuli, C. H., Manolescu, I. G., Udrea, A., Burdaeva, O., Byakhov, M., Filippov, A., Lazarev, S., Mosin, I., Orlov, S., Udovitsa, D., Khorinko, A., Protsenko, S., Chang, A., Lim, H. L., Tan, Y. O., Tan, E. H., Bastus Piulats, R., Garcia-Foncillas, J., Valdivia, J., de Castro, J., Domine Gomez, M., Kim, S. W., Lee, J. S., Kim, H. K., Lee, J. S., Shin, S. W., Kim, D. W., Kim, Y. C., Park, K. C., Chang, C. S., Chang, G. C., Goan, Y. G., Su, W. C., Tsai, C. M., Kuo, H. P., Benekli, M., Demir, G., Gokmen, E., Sevinc, A., Crawford, J., Giaccone, G., Haigentz, M., Owonikoko, T., Agarwal, M., Pandit, S., Araujo, R., Vrindavanam, N., Bonomi, P., Berg, A., Wade, J., Bloom, R., Amin, B., Camidge, R., Hill, D., Rarick, M., Flynn, P., Klein, L., Lo Russo, K., Neubauer, M., Richards, P., Ruxer, R., Savin, M., Weckstein, D., Rosenberg, R., Whittaker, T., Richards Berry, D., Ottensmeier, C., Dangoor, A., Steele, N., Summers, Y., Rankin, E., Rowley, K., Giridharan, S., Kristeleit, H., Humber, C. & Taylor, P., Nov 2013, In : Annals of Oncology. 24, 11, p. 2875-2880 6 p., mdt371.

Research output: Contribution to journalArticle

33 Scopus citations
75 Scopus citations
1 Scopus citations
2012

Mechanisms of resistance to vascular endothelial growth factor blockade

Abdullah, S. E. & Perez-Soler, R., Jul 15 2012, In : Cancer. 118, 14, p. 3455-3467 13 p.

Research output: Contribution to journalReview article

56 Scopus citations

Phase-I/II study of bortezomib in combination with carboplatin and bevacizumab as first-line therapy in patients with advanced non-small-cell lung cancer

Piperdi, B., Walsh, W. V., Bradley, K., Zhou, Z., Bathini, V., Hanrahan-Boshes, M., Hutchinson, L. & Perez-Soler, R., Jun 2012, In : Journal of Thoracic Oncology. 7, 6, p. 1032-1040 9 p.

Research output: Contribution to journalArticle

22 Scopus citations
9 Scopus citations
2011

Bortezomib: Understanding the mechanism of action

Piperdi, B., Ling, Y. H., Liebes, L., Muggia, F. & Perez-Soler, R., Nov 1 2011, In : Molecular cancer therapeutics. 10, 11, p. 2029-2030 2 p.

Research output: Contribution to journalShort survey

34 Scopus citations

Both gene amplification and allelic loss occur at 14q13.3 in lung cancer

Harris, T., Pan, Q., Sironi, J., Lutz, D., Tian, J., Sapkar, J., Perez-Soler, R., Keller, S. & Locker, J., Feb 15 2011, In : Clinical Cancer Research. 17, 4, p. 690-699 10 p.

Research output: Contribution to journalArticle

30 Scopus citations
53 Scopus citations

The phosphatase inhibitor menadione (Vitamin K3) protects cells from EGFR inhibition by erlotinib and cetuximab

Perez-Soler, R., Zou, Y., Li, T. & Ling, Y. H., Nov 1 2011, In : Clinical Cancer Research. 17, 21, p. 6766-6777 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Treatment of non-small-cell lung cancer with erlotinib or gefitinib

Cataldo, V. D., Gibbons, D. L., Pérez-Soler, R. & Quintás-Cardama, A., Mar 10 2011, In : New England Journal of Medicine. 364, 10, p. 947-955 9 p.

Research output: Contribution to journalArticle

290 Scopus citations
2010

EGFR TKIs for advanced NSCLC: Practical questions

Perez-Soler, R., May 2010, In : ONCOLOGY. 24, 5

Research output: Contribution to journalComment/debate

2 Scopus citations