• 1517 Citations
  • 18 h-Index
20052020

Research output per year

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Publications

  • 1517 Citations
  • 18 h-Index
  • 31 Article
  • 3 Comment/debate
  • 2 Chapter
  • 1 Review article
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Article
2020

A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition

Dieterle, M. E., Haslwanter, D., Bortz, R. H., Wirchnianski, A. S., Lasso, G., Vergnolle, O., Abbasi, S. A., Fels, J. M., Laudermilch, E., Florez, C., Mengotto, A., Kimmel, D., Malonis, R. J., Georgiev, G., Quiroz, J., Barnhill, J., Pirofski, L. A., Daily, J. P., Dye, J. M., Lai, J. R. & 3 others, Herbert, A. S., Chandran, K. & Jangra, R. K., Sep 9 2020, In : Cell Host and Microbe. 28, 3, p. 486-496.e6

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

A virion-based assay for glycoprotein thermostability reveals key determinants of filovirus entry and its inhibition

Bortz, R. H., Wong, A. C., Grodus, M. G., Recht, H. S., Pulanco, M. C., Lasso, G., Anthony, S. J., Mittler, E., Jangra, R. K. & Chandran, K., Sep 1 2020, In : Journal of virology. 94, 18, e00336-20.

Research output: Contribution to journalArticle

HVEM signaling promotes protective antibody-dependent cellular cytotoxicity (ADCC) vaccine responses to herpes simplex viruses

Aschner, C. B., Loh, L. N., Galen, B., Delwel, I., Jangra, R. K., Garforth, S. J., Chandran, K., Almo, S., Jacobs, W. R., Ware, C. F. & Herold, B. C., Aug 2020, In : Science immunology. 5, 50, eaax2454.

Research output: Contribution to journalArticle

Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine

Wec, A. Z., Haslwanter, D., Abdiche, Y. N., Shehata, L., Pedreño-Lopez, N., Moyer, C. L., Bornholdt, Z. A., Lilov, A., Nett, J. H., Jangra, R. K., Brown, M., Watkins, D. I., Ahlm, C., Forsell, M. N., Rey, F. A., Barba-Spaeth, G., Chandran, K. & Walker, L. M., Mar 24 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 12, p. 6675-6685 11 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Oral Vaccination With Recombinant Vesicular Stomatitis Virus Expressing Sin Nombre Virus Glycoprotein Prevents Sin Nombre Virus Transmission in Deer Mice

Warner, B. M., Jangra, R., Griffin, B. D., Stein, D. R., Kobasa, D., Chandran, K., Kobinger, G. P. & Safronetz, D., Jul 8 2020, In : Frontiers in Cellular and Infection Microbiology. 10, 333.

Research output: Contribution to journalArticle

Open Access
2019

Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection

Wec, A. Z., Bornholdt, Z. A., He, S., Herbert, A. S., Goodwin, E., Wirchnianski, A. S., Gunn, B. M., Zhang, Z., Zhu, W., Liu, G., Abelson, D. M., Moyer, C. L., Jangra, R. K., James, R. M., Bakken, R. R., Bohorova, N., Bohorov, O., Kim, D. H., Pauly, M. H., Velasco, J. & 10 others, Bortz, R. H., Whaley, K. J., Goldstein, T., Anthony, S. J., Alter, G., Walker, L. M., Dye, J. M., Zeitlin, L., Qiu, X. & Chandran, K., Jan 9 2019, In : Cell Host and Microbe. 25, 1, p. 39-48.e5

Research output: Contribution to journalArticle

18 Scopus citations

Human, nonhuman primate, and bat cells are broadly susceptible to tibrovirus particle cell entry

Caì, Y., Yú, S., Jangra, R. K., Postnikova, E. N., Wada, J., Tesh, R. B., Whelan, S. P. J., Lauck, M., Wiley, M. R., Finch, C. L., Radoshitzky, S. R., O'Connor, D. H., Palacios, G., Chandran, K., Chiu, C. Y. & Kuhn, J. H., 2019, In : Frontiers in Microbiology. 10, APR, 856.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins

Quiroz, J. A., Malonis, R. J., Thackray, L. B., Cohen, C. A., Pallesen, J., Jangra, R. K., Brown, R. S., Hofmann, D., Holtsberg, F. W., Shulenin, S., Nyakatura, E. K., Durnell, L. A., Rayannavar, V., Daily, J. P., Ward, A. B., Javad Aman, M., Dye, J. M., Chandran, K., Diamond, M. S., Kielian, M. & 1 others, Lai, J. R., 2019, In : PLoS pathogens. 15, 11, e1008061.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Single dose of a rVSV-based vaccine elicits complete protection against severe fever with thrombocytopenia syndrome virus

Dong, F., Li, D., Wen, D., Li, S., Zhao, C., Qi, Y., Jangra, R. K., Wu, C., Xia, D., Zhang, X., Deng, F., Chandran, K., Zou, Z., Yuan, F. & Zheng, A., Dec 1 2019, In : npj Vaccines. 4, 1, 5.

Research output: Contribution to journalArticle

13 Scopus citations
3 Scopus citations

Vesicular stomatitis virus-based vaccines provide cross-protection against andes and sin nombre viruses

Warner, B. M., Stein, D. R., Jangra, R. K., Slough, M. M., Sroga, P., Sloan, A., Frost, K. L., Booth, S., Chandran, K. & Safronetz, D., Jul 2019, In : Viruses. 11, 7, 645.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

A naturally occurring antiviral ribonucleotide encoded by the human genome

Gizzi, A. S., Grove, T. L., Arnold, J. J., Jose, J., Jangra, R. K., Garforth, S. J., Du, Q., Cahill, S. M., Dulyaninova, N. G., Love, J. D., Chandran, K., Bresnick, A. R., Cameron, C. E. & Almo, S. C., Jun 28 2018, In : Nature. 558, 7711, p. 610-614 5 p.

Research output: Contribution to journalArticle

52 Scopus citations

Protocadherin-1 is essential for cell entry by New World hantaviruses

Jangra, R. K., Herbert, A. S., Li, R., Jae, L. T., Kleinfelter, L. M., Slough, M. M., Barker, S. L., Guardado-Calvo, P., Román-Sosa, G., Dieterle, M. E., Kuehne, A. I., Muena, N. A., Wirchnianski, A. S., Nyakatura, E. K., Fels, J. M., Ng, M., Mittler, E., Pan, J., Bharrhan, S., Wec, A. Z. & 9 others, Lai, J. R., Sidhu, S. S., Tischler, N. D., Rey, F. A., Moffat, J., Brummelkamp, T. R., Wang, Z., Dye, J. M. & Chandran, K., Nov 22 2018, In : Nature. 563, 7732, p. 559-563 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses

Goldstein, T., Anthony, S. J., Gbakima, A., Bird, B. H., Bangura, J., Tremeau-Bravard, A., Belaganahalli, M. N., Wells, H. L., Dhanota, J. K., Liang, E., Grodus, M., Jangra, R. K., DeJesus, V. A., Lasso, G., Smith, B. R., Jambai, A., Kamara, B. O., Kamara, S., Bangura, W., Monagin, C. & 7 others, Shapira, S., Johnson, C. K., Saylors, K., Rubin, E. M., Chandran, K., Lipkin, W. I. & Mazet, J. A. K., Oct 1 2018, In : Nature Microbiology. 3, 10, p. 1084-1089 6 p.

Research output: Contribution to journalArticle

90 Scopus citations
2017

Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses

Wec, A. Z., Herbert, A. S., Murin, C. D., Nyakatura, E. K., Abelson, D. M., Fels, J. M., He, S., James, R. M., de La Vega, M. A., Zhu, W., Bakken, R. R., Goodwin, E., Turner, H. L., Jangra, R. K., Zeitlin, L., Qiu, X., Lai, J. R., Walker, L. M., Ward, A. B., Dye, J. M. & 2 others, Chandran, K. & Bornholdt, Z. A., May 18 2017, In : Cell. 169, 5, p. 878-890.e15

Research output: Contribution to journalArticle

65 Scopus citations
2016

A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry

Maier, K. E., Jangra, R. K., Shieh, K. R., Cureton, D. K., Xiao, H., Snapp, E. L., Whelan, S. P., Chandran, K. & Levy, M., 2016, In : Molecular Therapy - Nucleic Acids. 5, p. e321

Research output: Contribution to journalArticle

24 Scopus citations

A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses

Wec, A. Z., Nyakatura, E. K., Herbert, A. S., Howell, K. A., Holtsberg, F. W., Bakken, R. R., Mittler, E., Christin, J. R., Shulenin, S., Jangra, R. K., Bharrhan, S., Kuehne, A. I., Bornholdt, Z. A., Flyak, A. I., Saphire, E. O., Crowe, J. E., Aman, M. J., Dye, J. M., Lai, J. R. & Chandran, K., Oct 21 2016, In : Science. 354, 6310, p. 350-354 5 p.

Research output: Contribution to journalArticle

57 Scopus citations

Direct visualization of Ebola virus fusion triggering in the endocytic pathway

Spence, J. S., Krause, T. B., Mittler, E., Jangra, R. K. & Chandran, K., Feb 9 2016, In : mBio. 7, 1, e01857-15.

Research output: Contribution to journalArticle

42 Scopus citations
2015

Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats

Ng, M., Ndungo, E., Kaczmarek, M. E., Herbert, A. S., Binger, T., Kuehne, A. I., Jangra, R. K., Hawkins, J. A., Gifford, R. J., Biswas, R., Demogines, A., James, R. M., Yu, M., Brummelkamp, T. R., Drosten, C., Wang, L. F., Kuhn, J. H., Müller, M. A., Dye, J. M., Sawyer, S. L. & 1 others, Chandran, K., Dec 23 2015, In : eLife. 4, DECEMBER2015, e11785.

Research output: Contribution to journalArticle

57 Scopus citations

Haploid genetic screen reveals a profound and direct dependence on cholesterol for hantavirus membrane fusion

Kleinfelter, L. M., Jangra, R. K., Jae, L. T., Herbert, A. S., Mittler, E., Stiles, K. M., Wirchnianski, A. S., Kielian, M., Brummelkamp, T. R., Dye, J. M. & Chandran, K., Jun 30 2015, In : mBio. 6, 4, e00801-15.

Research output: Contribution to journalArticle

48 Scopus citations
2014

Cell entry by a novel European filovirus requires host endosomal cysteine proteases and Niemann-Pick C1

Ng, M., Ndungo, E., Jangra, R. K., Cai, Y., Postnikova, E., Radoshitzky, S. R., Dye, J. M., Ramírez de Arellano, E., Negredo, A., Palacios, G., Kuhn, J. H. & Chandran, K., Nov 1 2014, In : Virology. 468, p. 637-646 10 p.

Research output: Contribution to journalArticle

38 Scopus citations
2012

Base Pairing between Hepatitis C Virus RNA and microrna 122 3' of its seed sequence is essential for genome stabilization and production of infectious virus

Shimakami, T., Yamane, D., Welsch, C., Hensley, L., Jangra, R. K. & Lemon, S. M., Jul 2012, In : Journal of virology. 86, 13, p. 7372-7383 12 p.

Research output: Contribution to journalArticle

65 Scopus citations

Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex

Shimakami, T., Yamane, D., Jangra, R. K., Kempf, B. J., Spaniel, C., Barton, D. J. & Lemon, S. M., Jan 17 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 3, p. 941-946 6 p.

Research output: Contribution to journalArticle

246 Scopus citations
2011

The antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5A

Helbig, K. J., Eyre, N. S., Yip, E., Narayana, S., Li, K., Fiches, G., Mccartney, E. M., Jangra, R. K., Lemon, S. M. & Beard, M. R., Nov 2011, In : Hepatology. 54, 5, p. 1506-1517 12 p.

Research output: Contribution to journalArticle

127 Scopus citations
2010

DDX6 (Rck/p54) is required for efficient hepatitis C virus replication but not for internal ribosome entry site-directed translation

Jangra, R. K., Yi, M. K. & Lemon, S. M., Jul 2010, In : Journal of virology. 84, 13, p. 6810-6824 15 p.

Research output: Contribution to journalArticle

83 Scopus citations

Inhibition of protease-inhibitor-resistant hepatitis C virus replicons and infectious virus by intracellular intrabodies

Gal-Tanamy, M., Zemel, R., Bachmatov, L., Jangra, R. K., Shapira, A., Villanueva, R. A., Yi, M. K., Lemon, S. M., Benhar, I. & Tur-Kaspa, R., Oct 2010, In : Antiviral Research. 88, 1, p. 95-106 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

MiR-122 does not modulate the elongation phase of hepatitis C virus RNA synthesis in isolated replicase complexes

Villanueva, R. A., Jangra, R. K., Yi, M. K., Pyles, R., Bourne, N. & Lemon, S. M., Oct 2010, In : Antiviral Research. 88, 1, p. 119-123 5 p.

Research output: Contribution to journalArticle

39 Scopus citations

Regulation of hepatitis C virus translation and infectious virus production by the MicroRNA miR-122

Jangra, R. K., Yi, M. K. & Lemon, S. M., Jul 2010, In : Journal of virology. 84, 13, p. 6615-6625 11 p.

Research output: Contribution to journalArticle

242 Scopus citations

Viral induction of the zinc finger antiviral protein is IRF3-dependent but NF-κB-independent

Wang, N., Dong, Q., Li, J., Jangra, R. K., Fan, M., Brasier, A. R., Lemon, S. M., Pfeffer, L. M. & Li, K., Feb 26 2010, In : Journal of Biological Chemistry. 285, 9, p. 6080-6090 11 p.

Research output: Contribution to journalArticle

42 Scopus citations
2007

Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus

Chen, Z., Rijnbrand, R., Jangra, R. K., Devaraj, S. G., Qu, L., Ma, Y., Lemon, S. M. & Li, K., Sep 30 2007, In : Virology. 366, 2, p. 277-292 16 p.

Research output: Contribution to journalArticle

83 Scopus citations
2005
31 Scopus citations