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Richard M. LoPachin, Ph.D.

  • 4296 Citations
  • 39 h-Index
1977 …2019
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  • 4 Similar Profiles
Acrylamide Medicine & Life Sciences
Axons Medicine & Life Sciences
Rats Chemical Compounds
Peripheral Nerves Medicine & Life Sciences
Toxicity Chemical Compounds
Acrolein Medicine & Life Sciences
Neurons Chemical Compounds
Schwann Cells Medicine & Life Sciences

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Grants 1986 2018

MOLECULAR MECHANISMS OF HEXACARBON INDUCED AXON ATROPHY

LoPachin, R. M.

National Institutes of Health

1/1/97 → 5/31/11

Project: Research project

Atrophy
Axons
Intermediate Filaments
Methyl n-Butyl Ketone
Pyrroles

ROLE OF CALCIUM IN ACRYLAMIDE NEUROTOXICITY

LoPachin, R. M.

National Institutes of Health

8/1/86 → 7/31/18

Project: Research project

Acrylamide
Alkenes
Calcium
Axons
Research

Publications 1977 2019

  • 4296 Citations
  • 39 h-Index
  • 111 Article
  • 2 Review article
  • 1 Chapter
2 Citations (Scopus)

Mechanisms of soft and hard electrophile toxicities

LoPachin, R. M., Geohagen, B. C. & Nordstroem, L. R., Apr 15 2019, In : Toxicology. 418, p. 62-69 8 p.

Research output: Contribution to journal › Review article

Nucleophiles
Toxicology
Toxicity
Organic Chemistry
Electrons
2 Citations (Scopus)

Phloretin cytoprotection and toxicity

Geohagen, B. C., Korsharskyy, B., Vydyanatha, A., Nordstroem, L. R. & LoPachin, R. M., Dec 25 2018, In : Chemico-Biological Interactions. 296, p. 117-123 7 p.

Research output: Contribution to journal › Article

Phloretin
Cytoprotection
Toxicity
Acetaminophen
Poisons
3 Citations (Scopus)

Enolate-Forming Compounds as a Novel Approach to Cytoprotection

LoPachin, R. M., Geohagen, B. C., Nordstroem, L. R. & Gavin, T., Dec 19 2016, In : Chemical Research in Toxicology. 29, 12, p. 2096-2107 12 p.

Research output: Contribution to journal › Review article

Cytoprotection
Poisons
Phloretin
Tacrine
Curcumin
3 Citations (Scopus)

Enolate-forming phloretin pharmacophores: Hepatoprotection in an experimental model of drug-induced toxicity

Geohagen, B. C., Vydyanathan, A., Kosharskyy, B., Shaparin, N., Gavin, T. & LoPachin, R. M., Jun 1 2016, In : Journal of Pharmacology and Experimental Therapeutics. 357, 3, p. 476-486 11 p.

Research output: Contribution to journal › Article

Phloretin
Acetaminophen
Drug-Related Side Effects and Adverse Reactions
Phloroglucinol
Theoretical Models
5 Citations (Scopus)

Joint toxic effects of the type-2 alkene electrophiles

Zhang, L., Geohagen, B. C., Gavin, T. & LoPachin, R. M., Jul 25 2016, In : Chemico-Biological Interactions. 254, p. 198-206 9 p.

Research output: Contribution to journal › Article

Poisons
Alkenes
Proteome
Toxicity
Acrolein