• 852 Citations
  • 16 h-Index
20102020

Research output per year

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Publications

2020

Comparing the Neuroprotective Effects of Caffeic Acid in Rat Cortical Slices and Caenorhabditis elegans: Involvement of Nrf2 and SKN-1 Signaling Pathways

Colonnello, A., Aguilera-Portillo, G., Rubio-López, L. C., Robles-Bañuelos, B., Rangel-López, E., Cortez-Núñez, S., Evaristo-Priego, Y., Silva-Palacios, A., Galván-Arzate, S., García-Contreras, R., Túnez, I., Chen, P., Aschner, M. & Santamaría, A., Feb 1 2020, In : Neurotoxicity Research. 37, 2, p. 326-337 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Correction to: Comparing the Neuroprotective Effects of Caffeic Acid in Rat Cortical Slices and Caenorhabditis elegans: Involvement of Nrf2 and SKN-1 Signaling Pathways (Neurotoxicity Research, (2020), 37, 2, (326-337), 10.1007/s12640-019-00133-8)

Colonnello, A., Aguilera-Portillo, G., Rubio-López, L. C., Robles-Bañuelos, B., Rangel-López, E., Cortez-Núñez, S., Evaristo-Priego, Y., Silva-Palacios, A., Galván-Arzate, S., García-Contreras, R., Túnez, I., Chen, P., Aschner, M. & Santamaría, A., Mar 1 2020, In : Neurotoxicity Research. 37, 3, 1 p.

Research output: Contribution to journalComment/debate

Open Access
2019

A C. elegans Model for the Study of RAGE-Related Neurodegeneration

Pinkas, A., Lee, K. H., Chen, P. & Aschner, M., Jan 1 2019, In : Neurotoxicity Research. 35, 1, p. 19-28 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Caenorhabditis elegans and its applicability to studies on restless legs syndrome

Chen, P., Ijomone, O. M., Lee, K. H. & Aschner, M., 2019, Advances in Pharmacology. Clemens, S. & Ghorayeb, I. (eds.). Academic Press Inc., p. 147-174 28 p. (Advances in Pharmacology; vol. 84).

Research output: Chapter in Book/Report/Conference proceedingChapter

Iron and manganese-related CNS toxicity: mechanisms, diagnosis and treatment

Chen, P., Totten, M., Zhang, Z., Bucinca, H., Erikson, K., Santamaría, A., Bowman, A. B. & Aschner, M., Mar 4 2019, In : Expert review of neurotherapeutics. 19, 3, p. 243-260 18 p.

Research output: Contribution to journalReview article

6 Scopus citations

Triclosan induces PC12 cells injury is accompanied by inhibition of AKT/mTOR and activation of p38 pathway

Li, S. J., Chen, P., Peres, T. V., Villahoz, B. F., Zhang, Z., Miah, M. R. & Aschner, M., Sep 2019, In : Neurotoxicology. 74, p. 221-229 9 p.

Research output: Contribution to journalArticle

2018

Manganese metabolism in humans

Chen, P., Bornhorst, J. & Aschner, M., Mar 1 2018, In : Frontiers in Bioscience - Landmark. 23, 9, p. 1655-1679 25 p.

Research output: Contribution to journalArticle

45 Scopus citations

Mechanisms and Disease Pathogenesis Underlying Metal-Induced Oxidative Stress

Chen, P., Bornhorst, J., Diana Neely, M. & Avila, D. S., Jan 1 2018, In : Oxidative Medicine and Cellular Longevity. 2018, 1 p.

Research output: Contribution to journalEditorial

4 Scopus citations

PI3K/Akt signaling pathway and Hsp70 activate in hippocampus of rats with chronic manganese sulfate exposure

Cheng, H., Xia, B., Su, C., Chen, K., Chen, X., Chen, P., Zou, Y. & Yang, X., Dec 2018, In : Journal of Trace Elements in Medicine and Biology. 50, p. 332-338 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
2016

Exposure, epidemiology, and mechanism of the environmental toxicant manganese

Chen, P., Culbreth, M. & Aschner, M., Apr 22 2016, (Accepted/In press) In : Environmental Science and Pollution Research. p. 1-9 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Extracellular dopamine and alterations on dopamine transporter are related to reserpine toxicity in Caenorhabditis elegans

Reckziegel, P., Chen, P., Caito, S., Gubert, P., Soares, F. A. A., Fachinetto, R. & Aschner, M., Mar 1 2016, In : Archives of Toxicology. 90, 3, p. 633-645 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Guarana (Paullinia cupana Mart.) attenuates methylmercury-induced toxicity in Caenorhabditis elegans

Arantes, L. P., Peres, T. V., Chen, P., Caito, S. W., Aschner, M. & Soares, F. A. A., 2016, In : Toxicology Research. 5, 6, p. 1629-1638 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

"Manganese-induced neurotoxicity: A review of its behavioral consequences and neuroprotective strategies"

Peres, T. V., Schettinger, M. R. C., Chen, P., Carvalho, F., Avila, D. S., Bowman, A. B. & Aschner, M., Nov 4 2016, In : BMC Pharmacology and Toxicology. 17, 1, 57.

Research output: Contribution to journalReview article

86 Scopus citations

Metals and Neurodegeneration

Chen, P., Miah, M. R. & Aschner, M., Jan 1 2016, In : F1000Research. 5, 7431.1.

Research output: Contribution to journalReview article

52 Scopus citations

The use of the nematode Caenorhabditis elegans to evaluate the adverse effects of epoxiconazole exposure on spermatogenesis

Li, Y., Zhang, M., Li, S., Lv, R., Chen, P., Liu, R., Liang, G. & Yin, L., Oct 1 2016, In : International Journal of Environmental Research and Public Health. 13, 10, 993.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Age- And manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease

Chen, P., DeWitt, M. R., Bornhorst, J., Soares, F. A., Mukhopadhyay, S., Bowman, A. B. & Aschner, M., Mar 1 2015, In : Metallomics. 7, 2, p. 289-298 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Effects of microcystin-LR exposure on spermiogenesis in nematode caenorhabditis elegans

Li, Y., Zhang, M., Chen, P., Liu, R., Liang, G., Yin, L. & Pu, Y., Sep 22 2015, In : International Journal of Molecular Sciences. 16, 9, p. 22927-22937 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans

Chakraborty, S., Chen, P., Bornhorst, J., Schwerdtle, T., Schumacher, F., Kleuser, B., Bowman, A. B. & Aschner, M., May 1 2015, In : Metallomics. 7, 5, p. 847-856 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Manganese homeostasis in the nervous system

Chen, P., Chakraborty, S., Mukhopadhyay, S., Lee, E., Paoliello, M. M. B., Bowman, A. B. & Aschner, M., Aug 1 2015, In : Journal of Neurochemistry. 134, 4, p. 601-610 10 p.

Research output: Contribution to journalReview article

106 Scopus citations

Manganese-induced neurotoxicity: From C. elegans to humans

Chen, P., Chakraborty, S., Peres, T. V., Bowman, A. B. & Aschner, M., Mar 1 2015, In : Toxicology Research. 4, 2, p. 191-202 12 p.

Research output: Contribution to journalReview article

34 Scopus citations

Metal Toxicology

Martinez-Finley, E. J., Caito, S., Fretham, S., Chen, P. & Aschner, M., Mar 27 2015, Mammalian Toxicology. Wiley Blackwell, p. 171-185 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2014

Genetic factors and manganese-induced neurotoxicity

Chen, P., Parmalee, N. & Aschner, M., Jan 1 2014, In : Frontiers in Genetics. 5, AUG, Article 265.

Research output: Contribution to journalShort survey

53 Scopus citations

Manganese

Chakraborty, S., Martinez-Finley, E., Caito, S., Chen, P. & Aschner, M., Jan 1 2014, In : RSC Metallobiology. 2014-January, 2, p. 260-281 22 p.

Research output: Contribution to journalReview article

2 Scopus citations

SLC30A10 is a cell surface-localized manganese efflux transporter, And parkinsonism-causing mutations block its intracellular trafficking and efflux activity

Leyva-Illades, D., Chen, P., Zogzas, C. E., Hutchens, S., Mercado, J. M., Swaim, C. D., Morrisett, R. A., Bowman, A. B., Aschner, M. & Mukhopadhyay, S., Oct 15 2014, In : Journal of Neuroscience. 34, 42, p. 14079-14095 17 p.

Research output: Contribution to journalArticle

95 Scopus citations

TorsinA rescues ER-associated stress and locomotive defects in C. elegans models of ALS

Thompson, M. L., Chen, P., Yan, X., Kim, H., Borom, A. R., Roberts, N. B., Caldwell, K. A. & Caldwell, G. A., Feb 1 2014, In : DMM Disease Models and Mechanisms. 7, 2, p. 233-243 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
2013

Manganese efflux in Parkinsonism: Insights from newly characterized SLC30A10 mutations

DeWitt, M. R., Chen, P. & Aschner, M., Mar 1 2013, In : Biochemical and Biophysical Research Communications. 432, 1, p. 1-4 4 p.

Research output: Contribution to journalShort survey

29 Scopus citations

Metal-induced neurodegeneration in C. elegans

Chen, P., Martinez-Finley, E. J., Bornhorst, J., Chakraborty, S. & Aschner, M., Sep 11 2013, In : Frontiers in Aging Neuroscience. 5, MAY, Article 18.

Research output: Contribution to journalReview article

30 Scopus citations
2012

Genome-wide analyses of metal responsive genes in Caenorhabditis elegans

Caito, S., Fretham, S., Martinez-Finley, E., Chakraborty, S., Avila, D., Chen, P. & Aschner, M., Dec 1 2012, In : Frontiers in Genetics. 3, APR, Article 52.

Research output: Contribution to journalReview article

9 Scopus citations

The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response

Chen, P., Burdette, A. J., Porter, J. C., Ricketts, J. C., Fox, S. A., Nery, F. C., Hewett, J. W., Berkowitz, L. A., Breakefield, X. O., Caldwell, K. A. & Caldwell, G. A., Mar 1 2012, In : Human molecular genetics. 21, 5, 1 p., ddr571.

Research output: Contribution to journalComment/debate

2011

TorsinA participates in endoplasmic reticulum-associated degradation

Nery, F. C., Armata, I. A., Farley, J. E., Cho, J. A., Yaqub, U., Chen, P., Da Hora, C. C., Wang, Q., Tagaya, M., Klein, C., Tannous, B., Caldwell, K. A., Caldwell, G. A., Lencer, W. I., Ye, Y. & Breakefield, X. O., Jul 19 2011, In : Nature communications. 2, 1, 393.

Research output: Contribution to journalArticle

68 Scopus citations
2010

Chemical enhancement of torsinA function in cell and animal models of torsion dystonia

Cao, S., Hewett, J. W., Yokoi, F., Lu, J., Buckley, A. C., Burdette, A. J., Chen, P., Nery, F. C., Li, Y., Breakefield, X. O., Caldwell, G. A. & Caldwell, K. A., May 1 2010, In : DMM Disease Models and Mechanisms. 3, 5-6, p. 386-396 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response

Chen, P., Burdette, A. J., Porter, J. C., Ricketts, J. C., Fox, S. A., Nery, F. C., Hewett, J. W., Berkowitz, L. A., Breakefield, X. O., Caldwell, K. A. & Caldwell, G. A., Jun 28 2010, In : Human molecular genetics. 19, 18, p. 3502-3515 14 p., ddq266.

Research output: Contribution to journalArticle

65 Scopus citations