• 16965 Citations
  • 71 h-Index
19952020

Research output per year

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Publications

2020

Chemokines in Myocardial Infarction

Chen, B. & Frangogiannis, N. G., 2020, (Accepted/In press) In : Journal of Cardiovascular Translational Research.

Research output: Contribution to journalReview article

Extracellular matrix-derived peptides in tissue remodeling and fibrosis

de Castro Brás, L. E. & Frangogiannis, N. G., Sep 2020, In : Matrix Biology. 91-92, p. 176-187 12 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Extracellular Matrix in Ischemic Heart Disease, Part 4/4: JACC Focus Seminar

Frangogiannis, N. G. & Kovacic, J. C., May 5 2020, In : Journal of the American College of Cardiology. 75, 17, p. 2219-2235 17 p.

Research output: Contribution to journalReview article

The role of Smad2 and Smad3 in regulating homeostatic functions of fibroblasts in vitro and in adult mice

Huang, S., Chen, B., Humeres, C., Alex, L., Hanna, A. & Frangogiannis, N. G., Jul 2020, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1867, 7, 118703.

Research output: Contribution to journalArticle

2019

Can Myocardial Fibrosis Be Reversed?

Frangogiannis, N. G., May 14 2019, In : Journal of the American College of Cardiology. 73, 18, p. 2283-2285 3 p.

Research output: Contribution to journalEditorial

4 Scopus citations
80 Scopus citations

Distinct roles of myofibroblast-specific Smad2 and Smad3 signaling in repair and remodeling of the infarcted heart

Huang, S., Chen, B., Su, Y., Alex, L., Humeres, C., Shinde, A. V., Conway, S. J. & Frangogiannis, N. G., Jul 2019, In : Journal of Molecular and Cellular Cardiology. 132, p. 84-97 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Fibroblasts in the Infarcted, Remodeling, and Failing Heart

Humeres, C. & Frangogiannis, N. G., Jun 1 2019, In : JACC: Basic to Translational Science. 4, 3, p. 449-467 19 p.

Research output: Contribution to journalReview article

Open Access
17 Scopus citations

How do endosomal toll-like receptors sense and extend ischaemic myocardial injury?

Frangogiannis, N. G., Oct 1 2019, In : Cardiovascular research. 115, 12, p. 1687-1689 3 p.

Research output: Contribution to journalEditorial

Immune cells as targets for cardioprotection: New players and novel therapeutic opportunities

Andreadou, I., Cabrera-Fuentes, H. A., Devaux, Y., Frangogiannis, N. G., Frantz, S., Guzik, T., Liehn, E. A., Gomes, C. P. C., Schulz, R. & Hausenloy, D. J., Jun 1 2019, In : Cardiovascular research. 115, 7, p. 1117-1130 14 p.

Research output: Contribution to journalReview article

Open Access
24 Scopus citations

Macrophage Smad3 protects the infarcted heart, stimulating phagocytosis and regulating inflammation

Chen, B., Huang, S., Su, Y., Wu, Y. J., Hanna, A., Brickshawana, A., Graff, J. & Frangogiannis, N. G., 2019, In : Circulation research. 125, 1, p. 55-70 16 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Monocyte subsets as predictors of adverse events in patients with atherosclerosis

Frangogiannis, N. G., Sep 1 2019, In : Hellenic Journal of Cardiology. 60, 5, p. 322-323 2 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations

Protean Functions and Phenotypic Plasticity of Regulatory T Cells in Chronic Ischemic Heart Failure

Frangogiannis, N. G., Jan 8 2019, In : Circulation. 139, 2, p. 222-225 4 p.

Research output: Contribution to journalReview article

1 Scopus citations

Protective Effects of Activated Myofibroblasts in the Pressure-Overloaded Myocardium Are Mediated Through Smad-Dependent Activation of a Matrix-Preserving Program

Russo, I., Cavalera, M., Huang, S., Su, Y., Hanna, A., Chen, B., Shinde, A. V., Conway, S. J., Graff, J. & Frangogiannis, N. G., Apr 12 2019, In : Circulation research. 124, 8, p. 1214-1227 14 p.

Research output: Contribution to journalArticle

18 Scopus citations
2 Scopus citations

The cell biological basis for primary unloading in acute myocardial infarction

Hanna, A. & Frangogiannis, N. G., Oct 15 2019, In : International Journal of Cardiology. 293, p. 45-47 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations

The extracellular matrix in ischemic and nonischemic heart failure

Frangogiannis, N. G., Jan 1 2019, In : Circulation research. 125, 1, p. 117-146 30 p.

Research output: Contribution to journalReview article

Open Access
23 Scopus citations

The Functional Heterogeneity of Resident Cardiac Macrophages in Myocardial Injury: CCR2+ Cells Promote Inflammation, whereas CCR2- Cells Protect

Chen, B., Brickshawana, A. & Frangogiannis, N. G., Jan 18 2019, In : Circulation research. 124, 2, p. 183-185 3 p.

Research output: Contribution to journalReview article

3 Scopus citations

The Role of the TGF-β Superfamily in Myocardial Infarction

Hanna, A. & Frangogiannis, N. G., Sep 18 2019, In : Frontiers in Cardiovascular Medicine. 6, 140.

Research output: Contribution to journalReview article

Open Access
7 Scopus citations
2018

Aging, cardiac repair and Smad3

Chen, B., Huang, S. & Frangogiannis, N. G., Sep 1 2018, In : Aging. 10, 9, p. 2230-2232 3 p.

Research output: Contribution to journalComment/debate

Anti-inflammatory therapies in myocardial infarction: failures, hopes and challenges

Huang, S. & Frangogiannis, N. G., May 2018, In : British Journal of Pharmacology. 175, 9, p. 1377-1400 24 p.

Research output: Contribution to journalReview article

37 Scopus citations

Cell biological mechanisms in regulation of the post-infarction inflammatory response

Frangogiannis, N. G., Feb 2018, In : Current Opinion in Physiology. 1, p. 7-13 7 p.

Research output: Contribution to journalReview article

15 Scopus citations

Cell therapy for peripheral artery disease

Frangogiannis, N. G., Apr 2018, In : Current Opinion in Pharmacology. 39, p. 27-34 8 p.

Research output: Contribution to journalReview article

11 Scopus citations
18 Scopus citations

Galectin-3 in the fibrotic response: Cellular targets and molecular mechanisms

Frangogiannis, N. G., May 1 2018, In : International Journal of Cardiology. 258, p. 226-227 2 p.

Research output: Contribution to journalEditorial

5 Scopus citations
2 Scopus citations

Guidelines for experimental models of myocardial ischemia and infarction

Lindsey, M. L., Bolli, R., Canty, J. M., Du, X. J., Frangogiannis, N. G., Frantz, S., Gourdie, R. G., Holmes, J. W., Jones, S. P., Kloner, R. A., Lefer, D. J., Liao, R., Murphy, E., Ping, P., Przyklenk, K., Recchia, F. A., Longacre, L. S., Ripplinger, C. M., Van Eyk, J. E. & Heusch, G., Apr 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 314, 4, p. H812-H838

Research output: Contribution to journalReview article

124 Scopus citations

Opposing actions of fibroblast and cardiomyocyte smad3 signaling in the infarcted myocardium

Kong, P., Shinde, A. V., Su, Y., Russo, I., Chen, B., Saxena, A., Conway, S. J., Graff, J. M. & Frangogiannis, N. G., Feb 13 2018, In : Circulation. 137, 7, p. 707-724 18 p.

Research output: Contribution to journalArticle

38 Scopus citations
10 Scopus citations

Targeting mitochondrial calcium transport in myocardial infarction

Frangogiannis, N. G., Jul 1 2018, In : Hellenic Journal of Cardiology. 59, 4, p. 223-225 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations

The cellular origin of activated fibroblasts in the infarcted and remodeling myocardium

Alex, L. & Frangogiannis, N. G., Feb 2018, In : Circulation research. 122, 4, p. 540-542 3 p.

Research output: Contribution to journalReview article

11 Scopus citations

The Role of Macrophages in Nonischemic Heart Failure

Chen, B. & Frangogiannis, N. G., Apr 1 2018, In : JACC: Basic to Translational Science. 3, 2, p. 245-248 4 p.

Research output: Contribution to journalEditorial

5 Scopus citations

Tissue transglutaminase in the pathogenesis of heart failure

Shinde, A. V. & Frangogiannis, N. G., Mar 1 2018, In : Cell Death and Differentiation. 25, 3, p. 453-456 4 p.

Research output: Contribution to journalComment/debate

4 Scopus citations
2017

Fibroblasts and the extracellular matrix in right ventricular disease

Frangogiannis, N. G., Oct 1 2017, In : Cardiovascular research. 113, 12, p. 1453-1464 12 p.

Research output: Contribution to journalReview article

31 Scopus citations

Immune cells in repair of the infarcted myocardium

Chen, B. & Frangogiannis, N. G., Jan 1 2017, In : Microcirculation. 24, 1, e12305.

Research output: Contribution to journalReview article

37 Scopus citations

Left atrial remodeling, hypertrophy, and fibrosis in mouse models of heart failure

Hanif, W., Alex, L., Su, Y., Shinde, A. V., Russo, I., Li, N. & Frangogiannis, N. G., Sep 2017, In : Cardiovascular Pathology. 30, p. 27-37 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Mechanisms of Fibroblast Activation in the Remodeling Myocardium

Shinde, A. V. & Frangogiannis, N. G., Jun 1 2017, In : Current Pathobiology Reports. 5, 2, p. 145-152 8 p.

Research output: Contribution to journalReview article

13 Scopus citations

The extracellular matrix in myocardial injury, repair, and remodeling

Frangogiannis, N. G., May 1 2017, In : Journal of Clinical Investigation. 127, 5, p. 1600-1612 13 p.

Research output: Contribution to journalReview article

113 Scopus citations

The role of transforming growth factor (TGF)-β in the infarcted myocardium

Frangogiannis, N. G., Mar 1 2017, In : Journal of Thoracic Disease. 9, p. S52-S63

Research output: Contribution to journalReview article

47 Scopus citations
79 Scopus citations

Tissue transglutaminase induction in the pressure-overloaded myocardium regulates matrix remodelling

Shinde, A. V., Dobaczewski, M., De Haan, J. J., Saxena, A., Lee, K. K., Xia, Y., Chen, W., Su, Y., Hanif, W., Kaur Madahar, I., Paulino, V. M., Melino, G. & Frangogiannis, N. G., Jul 1 2017, In : Cardiovascular research. 113, 8, p. 892-905 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1

Wang, Y., Wu, B., Lu, P., Zhang, D., Wu, B., Varshney, S., Del Monte-Nieto, G., Zhuang, Z., Charafeddine, R., Kramer, A. H., Sibinga, N. E., Frangogiannis, N. G., Kitsis, R. N., Adams, R. H., Alitalo, K., Sharp, D. J., Harvey, R. P., Stanley, P. & Zhou, B., Dec 1 2017, In : Nature communications. 8, 1, 578.

Research output: Contribution to journalArticle

12 Scopus citations
2016

Authors' Reply

Frunza, O., Russo, I., Shinde, A. V., Su, Y. & Frangogiannis, N. G., Aug 1 2016, In : American Journal of Pathology. 186, 8, p. 2234-2235 2 p.

Research output: Contribution to journalLetter

Crossing into the Next Frontier of Cardiac Extracellular Matrix Research

Spinale, F. G., Frangogiannis, N. G., Hinz, B., Holmes, J. W., Kassiri, Z. & Lindsey, M. L., Oct 28 2016, In : Circulation research. 119, 10, p. 1040-1045 6 p.

Research output: Contribution to journalReview article

27 Scopus citations
137 Scopus citations

Fibroblast—Extracellular Matrix Interactions in Tissue Fibrosis

Frangogiannis, N. G., Mar 1 2016, In : Current Pathobiology Reports. 4, 1, p. 11-18 8 p.

Research output: Contribution to journalReview article

10 Scopus citations

Inflammation as a therapeutic target in myocardial infarction: Learning from past failures to meet future challenges

Saxena, A., Russo, I. & Frangogiannis, N. G., Jan 1 2016, In : Translational Research. 167, 1, p. 152-166 15 p.

Research output: Contribution to journalArticle

56 Scopus citations

Macrophages in the Remodeling Failing Heart

Chen, B. & Frangogiannis, N. G., Sep 16 2016, In : Circulation research. 119, 7, p. 776-778 3 p.

Research output: Contribution to journalReview article

20 Scopus citations