• 5391 Citations
  • 44 h-Index
1977 …2019

Research output per year

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Publications

  • 5391 Citations
  • 44 h-Index
  • 96 Article
  • 10 Review article
  • 4 Short survey
  • 1 Foreword/postscript
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Article

[11] Assay of phagosome-lysosome fusion

Kielian, M., Jan 1 1986, In : Methods in enzymology. 132, C, p. 257-267 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Acidification of endosome subpopulations in wild-type Chinese hamster ovary cells and temperature-sensitive acidification-defective mutants

Schmid, S., Fuchs, R., Kielian, M., Helenius, A. & Mellman, I., Jan 1 1989, In : Journal of Cell Biology. 108, 4, p. 1291-1300 10 p.

Research output: Contribution to journalArticle

Open Access
109 Scopus citations

A conserved histidine in the ij loop of the Semliki Forest virus E1 protein plays an important role in membrane fusion

Chanel-Vos, C. & Kielian, M., Dec 1 2004, In : Journal of virology. 78, 24, p. 13543-13552 10 p.

Research output: Contribution to journalArticle

53 Scopus citations

A key interaction between the alphavirus envelope proteins responsible for initial dimer dissociation during fusion

Fields, W. & Kielian, M., Apr 1 2013, In : Journal of virology. 87, 7, p. 3774-3781 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

A Mechanistic Paradigm for Broad-Spectrum Antivirals that Target Virus-Cell Fusion

Vigant, F., Lee, J., Hollmann, A., Tanner, L. B., Akyol Ataman, Z., Yun, T., Shui, G., Aguilar, H. C., Zhang, D., Meriwether, D., Roman-Sosa, G., Robinson, L. R., Juelich, T. L., Buczkowski, H., Chou, S., Castanho, M. A. R. B., Wolf, M. C., Smith, J. K., Banyard, A., Kielian, M. & 7 others, Reddy, S., Wenk, M. R., Selke, M., Santos, N. C., Freiberg, A. N., Jung, M. E. & Lee, B., Apr 1 2013, In : PLoS pathogens. 9, 4, e1003297.

Research output: Contribution to journalArticle

44 Scopus citations

An alphavirus E2 membrane-proximal domain promotes envelope protein lateral interactions and virus budding

Byrd, E. A. & Kielian, M., Nov 1 2017, In : mBio. 8, 6, e01564-17.

Research output: Contribution to journalArticle

10 Scopus citations

An alphavirus temperature-sensitive capsid mutant reveals stages of nucleocapsid assembly

Zheng, Y. & Kielian, M., Oct 1 2015, In : Virology. 484, p. 412-420 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Analysis of a Chinese hamster ovary cell mutant with defective mobilization of cholesterol from the plasma membrane to the endoplasmic reticulum

Jacobs, N. L., Andemariam, B., Underwood, K. W., Panchalingam, K., Sternberg, D., Kielian, M. & Liscum, L., Oct 1 1997, In : Journal of Lipid Research. 38, 10, p. 1973-1987 15 p.

Research output: Contribution to journalArticle

27 Scopus citations

An epitope of the Semliki Forest virus fusion protein exposed during virus-membrane fusion

Ahn, A., Klimjack, M. R., Chatterjee, P. K. & Kielian, M., Dec 1 1999, In : Journal of virology. 73, 12, p. 10029-10039 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

An interaction site of the envelope proteins of Semliki Forest virus that is preserved after proteolytic activation

Zhang, X. & Kielian, M., Jul 5 2005, In : Virology. 337, 2, p. 344-352 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

A single point mutation controls the cholesterol dependence of Semliki Forest virus entry and exit

Vashishtha, M., Phalen, T., Marquardt, M. T., Ryu, J. S., Ng, A. C. & Kielian, M., Jan 12 1998, In : Journal of Cell Biology. 140, 1, p. 91-99 9 p.

Research output: Contribution to journalArticle

114 Scopus citations

A Stable Prefusion Intermediate of the Alphavirus Fusion Protein Reveals Critical Features of Class II Membrane Fusion

Sánchez-San Martín, C., Sosa, H. & Kielian, M., Dec 11 2008, In : Cell Host and Microbe. 4, 6, p. 600-608 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

A toggle switch controls the low pH-triggered rearrangement and maturation of the dengue virus envelope proteins

Zheng, A., Yuan, F., Kleinfelter, L. M. & Kielian, M., May 20 2014, In : Nature communications. 5, 3877.

Research output: Contribution to journalArticle

25 Scopus citations

Biochemical consequences of a mutation that controls the cholesterol dependence of Semliki Forest virus fusion

Chatterjee, P. K., Vashishtha, M. & Kielian, M., Jul 17 2000, In : Journal of virology. 74, 4, p. 1623-1631 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Biosynthesis, maturation, and acid activation of the Semliki Forest virus fusion protein

Kielian, M., Jungerwirth, S., Ullrich Sayad, K. & DeCandido, S., Jan 1 1990, In : Journal of virology. 64, 10, p. 4614-4624 11 p.

Research output: Contribution to journalArticle

66 Scopus citations

BST2/Tetherin inhibition of alphavirus exit

Ooi, Y. S., Dubé, M. & Kielian, M., Apr 22 2015, In : Viruses. 7, 4, p. 2147-2167 21 p.

Research output: Contribution to journalArticle

17 Scopus citations

Calcium-Dependent Rubella Virus Fusion Occurs in Early Endosomes

Dubé, M., Etienne, L., Fels, M. & Kielian, M., 2016, In : Journal of Virology. 90, 14, p. 6303-6313 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Cell-cell interactions in blast transformation of rat lymphocytes by neuraminidase and galactose oxidase

Kielian, M. C., Beyer, C. F. & Bowers, W. E., Oct 1 1977, In : Experimental Cell Research. 109, 1, p. 211-221 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Characterization of phagosome-lysosome fusion in mouse macrophages

Kielian, M. C. & Cohn, Z. A., Jan 1 1979, In : Journal of Cell Biology. 83, 2 II, p. No. LP1306

Research output: Contribution to journalArticle

Cholesterol-depleted cells that are relatively permissive for Semliki Forest virus infection

Marquardt, M. T. & Kielian, M., Oct 1 1996, In : Virology. 224, 1, p. 198-205 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Cholesterol-independent targeting of Golgi membrane proteins in insect cells

Rolls, M. M., Marquardt, M. T., Kielian, M. & Machamer, C. E., Jan 1 1997, In : Molecular biology of the cell. 8, 11, p. 2111-2118 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Cholesterol is required for infection by Semliki Forest virus

Phalen, T. & Kielian, M., Feb 1991, In : Journal of Cell Biology. 112, 4, p. 615-623 9 p.

Research output: Contribution to journalArticle

Open Access
137 Scopus citations

Cholesterol is required in the exit pathway of Semliki Forest virus

Marquardt, M. T., Phalen, T. & Kielian, M., Oct 1993, In : Journal of Cell Biology. 123, 1, p. 57-65 9 p.

Research output: Contribution to journalArticle

Open Access
57 Scopus citations
11 Scopus citations

Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus

Gibbons, D. L., Vaney, M. C., Roussel, A., Vigouroux, A., Reilly, B., Lepault, J., Kielian, M. & Rey, F. A., Jan 22 2004, In : Nature. 427, 6972, p. 320-325 6 p.

Research output: Contribution to journalArticle

276 Scopus citations

Cross-inhibition of chikungunya virus fusion and infection by alphavirus E1 domain III proteins

Martín, C. S. S., Nanda, S., Zheng, Y., Fields, W. & Kielian, M., Jul 2013, In : Journal of virology. 87, 13, p. 7680-7687 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Differential cholesterol binding by class II fusion proteins determines membrane fusion properties

Umashankar, M., Sánchez-San Martín, C., Liao, M., Reilly, B., Guo, A., Taylor, G. & Kielian, M., Sep 1 2008, In : Journal of virology. 82, 18, p. 9245-9253 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Differential roles of two conserved glycine residues in the fusion peptide of Semliki Forest Virus

Shome, S. G. & Kielian, M., Jan 1 2001, In : Virology. 279, 1, p. 146-160 15 p.

Research output: Contribution to journalArticle

11 Scopus citations

Domain III from class II fusion proteins functions as a dominant-negative inhibitor of virus membrane fusion

Liao, M. & Kielian, M., Oct 1 2005, In : Journal of Cell Biology. 171, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

102 Scopus citations

E1 mutants identify a critical region in the trimer interface of the Semliki Forest virus fusion protein

Liu, C. Y. & Kielian, M., Nov 1 2009, In : Journal of virology. 83, 21, p. 11298-11306 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Effects of membrane potential and sphingolipid structures on fusion of Semliki Forest virus

Samsonov, A. V., Chatterjee, P. K., Razinkov, V. I., Eng, C. H., Kielian, M. & Cohen, F. S., Dec 1 2002, In : Journal of virology. 76, 24, p. 12691-12702 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

Effects of monovalent cations on Semliki Forest virus entry into BHK-21 cells

Helenius, A., Kielian, M., Wellsteed, J., Mellman, I. & Rudnick, G., Oct 23 1985, In : Journal of Biological Chemistry. 260, 9, p. 5691-5697 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

Engineered dengue virus domain III proteins elicit cross-neutralizing antibody responses in mice

Frei, J. C., Wirchnianski, A. S., Govero, J., Vergnolle, O., Dowd, K. A., Pierson, T. C., Kielian, M., Girvin, M. E., Diamond, M. S. & Lai, J. R., Sep 1 2018, In : Journal of virology. 92, 18, e01023.

Research output: Contribution to journalArticle

8 Scopus citations

Formation and characterization of the trimeric form of the fusion protein of Semliki Forest virus

Gibbons, D. L., Ahn, A., Chatterjee, P. K. & Kielian, M., Sep 2 2000, In : Journal of virology. 74, 17, p. 7772-7780 9 p.

Research output: Contribution to journalArticle

54 Scopus citations

Functions of the stem region of the Semliki Forest virus fusion protein during virus fusion and assembly

Liao, M. & Kielian, M., Nov 1 2006, In : Journal of virology. 80, 22, p. 11362-11369 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Furin processing and proteolytic activation of Semliki Forest virus

Zhang, X., Fugère, M., Day, R. & Kielian, M., Mar 1 2003, In : Journal of virology. 77, 5, p. 2981-2989 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

fus-1, a pH shift mutant of Semliki Forest virus, acts by altering spike subunit interactions via a mutation in the E2 subunit

Glomb-Reinmund, S. & Kielian, M., May 1 1998, In : Journal of virology. 72, 5, p. 4281-4287 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Fusion induced by a class II viral fusion protein, Semliki Forest virus E1, is dependent on the voltage of the target cell

Markosyan, R. M., Kielian, M. & Cohen, F. S., Oct 1 2007, In : Journal of virology. 81, 20, p. 11218-11225 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Genome-Wide RNAi Screen Identifies Novel Host Proteins Required for Alphavirus Entry

Ooi, Y. S., Stiles, K. M., Liu, C. Y., Taylor, G. M. & Kielian, M., Jan 1 2013, In : PLoS pathogens. 9, 12, p. 1-10 10 p., e1003835.

Research output: Contribution to journalArticle

47 Scopus citations

Growth and stability of a cholesterol-independent Semliki Forest virus mutant in mosquitoes

Ahn, A., Schoepp, R. J., Sternberg, D. & Kielian, M., Sep 30 1999, In : Virology. 262, 2, p. 452-456 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Haploid genetic screen reveals a profound and direct dependence on cholesterol for hantavirus membrane fusion

Kleinfelter, L. M., Jangra, R. K., Jae, L. T., Herbert, A. S., Mittler, E., Stiles, K. M., Wirchnianski, A. S., Kielian, M., Brummelkamp, T. R., Dye, J. M. & Chandran, K., Jun 30 2015, In : mBio. 6, 4, e00801-15.

Research output: Contribution to journalArticle

44 Scopus citations

Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins

Quiroz, J. A., Malonis, R. J., Thackray, L. B., Cohen, C. A., Pallesen, J., Jangra, R. K., Brown, R. S., Hofmann, D., Holtsberg, F. W., Shulenin, S., Nyakatura, E. K., Durnell, L. A., Rayannavar, V., Daily, J. P., Ward, A. B., Javad Aman, M., Dye, J. M., Chandran, K., Diamond, M. S., Kielian, M. & 1 others, Lai, J. R., Jan 1 2019, In : PLoS pathogens. 15, 11, e1008061.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Identification of a specific region in the E1 fusion protein involved in zinc inhibition of semliki forest virus fusion

Liu, C. Y. & Kielian, M., Apr 1 2012, In : Journal of virology. 86, 7, p. 3588-3594 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Imaging of the alphavirus capsid protein during virus replication

Zheng, Y. & Kielian, M., Sep 5 2013, In : Journal of virology. 87, 17, p. 9579-9589 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Imaging the alphavirus exit pathway

Martinez, M. G., Snapp, E. L., Perumal, G. S., Macaluso, F. P. & Kielian, M., Jun 2014, In : Journal of virology. 88, 12, p. 6922-6933 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Insertion of Dengue E into lipid bilayers studied by neutron reflectivity and molecular dynamics simulations

Vanegas, J. M., Heinrich, F., Rogers, D. M., Carson, B. D., La Bauve, S., Vernon, B. C., Akgun, B., Satija, S., Zheng, A., Kielian, M., Rempe, S. B. & Kent, M. S., May 2018, In : Biochimica et Biophysica Acta - Biomembranes. 1860, 5, p. 1216-1230 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Interactions involved in pH protection of the alphavirus fusion protein

Fields, W. & Kielian, M., Dec 1 2015, In : Virology. 486, p. 173-179 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Intercellular Extensions Are Induced by the Alphavirus Structural Proteins and Mediate Virus Transmission

Martinez, M. G. & Kielian, M., Dec 15 2016, In : PLoS Pathogens. 12, 12, e1006061.

Research output: Contribution to journalArticle

10 Scopus citations

Intralysosomal accumulation of polyanions. I. Fusion of pinocytic and phagocytic vacuoles with secondary lysosomes

Kielian, M. C., Steinman, R. M. & Cohn, Z. A., Jun 1 1982, In : Journal of Cell Biology. 93, 3, p. 866-874 9 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations
Open Access
40 Scopus citations