• 6547 Citations
  • 45 h-Index
1988 …2024

Research output per year

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Publications

2020

The damage response framework and infection prevention: From concept to bedside

Godbout, E. J., Madaline, T., Casadevall, A., Bearman, G. & Pirofski, L. A., Mar 1 2020, In : Infection Control and Hospital Epidemiology. 41, 3, p. 337-341 5 p.

Research output: Contribution to journalReview article

2019

Antibody Immunity and Natural Resistance to Cryptococcosis

Trevijano-Contador, N. & Pirofski, L., Jan 1 2019, In : Current Tropical Medicine Reports.

Research output: Contribution to journalReview article

1 Scopus citations

Antibody responses in HIV-infected patients with advanced immunosuppression and asymptomatic cryptococcal antigenemia

Hlupeni, A., Nakouzi, A., Wang, T., Boyd, K. F., Makadzange, T. A., Ndhlovu, C. E. & Pirofski, L., Jan 1 2019, In : Open Forum Infectious Diseases. 6, 1

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Association Between Plasma Antibody Responses and Risk for Cryptococcus-Associated Immune Reconstitution Inflammatory Syndrome

Yoon, H. A., Nakouzi, A., Chang, C. C., Kuniholm, M. H., Carreño, L. J., Wang, T., Ndung'u, T., Lewin, S. R., French, M. A. & Pirofski, L. A., Jan 9 2019, In : Journal of Infectious Diseases. 219, 3, p. 420-428 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Benefits and costs of animal virulence for microbes

Casadevall, A. & Pirofski, L., May 1 2019, In : mBio. 10, 3, e00863-19.

Research output: Contribution to journalShort survey

Open Access
3 Scopus citations

Double-edged role of interleukin 17a in streptococcus pneumoniae pathogenesis during influenza virus coinfection

Ambigapathy, G., Schmit, T., Mathur, R. K., Nookala, S., Bahri, S., Pirofski, L. A. & Khan, M. N., Jul 31 2019, In : Journal of Infectious Diseases. 220, 5, p. 902-912 11 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Risk factors of laryngeal cryptococcosis: A case report

Quintero, O., Trachuk, P., Lerner, M. Z., Sarungbam, J., Pirofski, L. A. & Park, S. O., Jun 2019, In : Medical Mycology Case Reports. 24, p. 82-85 4 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018
4 Scopus citations

Antibody and B cell subset perturbations in human immunodeficiency virus-uninfected patients with cryptococcosis

Rohatgi, S., Nakouzi, A., Carreño, L. J., Slosar-Cheah, M., Kuniholm, M. H., Wang, T., Pappas, P. G. & Pirofski, L. A., Jan 1 2018, In : Open Forum Infectious Diseases. 5, 1, ofx255.

Research output: Contribution to journalArticle

9 Scopus citations

A Therapeutic Vaccine for Recurrent Vulvovaginal Candidiasis

Casadevall, A. & Pirofski, L., Jun 1 2018, In : Clinical Infectious Diseases. 66, 12, p. 1937-1939 3 p.

Research output: Contribution to journalReview article

2 Scopus citations

Naïve B cells reduce fungal dissemination in cryptococcus neoformans infected Rag1-/- mice

Dufaud, C., Rivera, J., Rohatgi, S. & Pirofski, L. A., Oct 3 2018, In : Virulence. 9, 1, p. 173-184 12 p.

Research output: Contribution to journalArticle

8 Scopus citations
9 Scopus citations

Virulence profile: Liise-anne Pirofski

Pirofski, L., Jan 1 2018, In : Virulence. 9, 1, p. 275-277 3 p.

Research output: Contribution to journalComment/debate

What is a host? Attributes of individual susceptibility

Casadevall, A. & Pirofski, L. A., Feb 1 2018, In : Infection and Immunity. 86, 2, e00636-17.

Research output: Contribution to journalShort survey

14 Scopus citations
2017

A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine

Schumann, B., Hahm, H. S., Parameswarappa, S. G., Reppe, K., Wahlbrink, A., Govindan, S., Kaplonek, P., Pirofski, L., Witzenrath, M., Anish, C., Pereira, C. L. & Seeberger, P. H., Mar 8 2017, In : Science Translational Medicine. 9, 380, eaaf5347.

Research output: Contribution to journalArticle

27 Scopus citations

Bundle in the bronx: Impact of a transition-of-care outpatient parenteral antibiotic therapy bundle on all- cause 30-day hospital readmissions

Madaline, T., Nori, P., Mowrey, W., Zukowski, E., Gohil, S., Sarwar, U., Weston, G., Urrely, R., Palombelli, M., Pierino, V. F., Parsons, V., Ehrlich, A., Ostrowsky, B., Corpuz, M. & Pirofski, L. A., Mar 1 2017, In : Open Forum Infectious Diseases. 4, 2, ofx097.

Research output: Contribution to journalArticle

12 Scopus citations

Help is on the way: Monoclonal antibody therapy for multi-drug resistant bacteria

Babb, R. & Pirofski, L., Apr 13 2017, (Accepted/In press) In : Virulence. p. 1-4 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Immune-mediated damage completes the parabola: Cryptococcus neoformans pathogenesis can reflect the outcome of a weak or strong immune response

Pirofski, L. & Casadevall, A., Nov 1 2017, In : mBio. 8, 6, e02063-17.

Research output: Contribution to journalComment/debate

22 Scopus citations

Life as an Infectious Diseases Physician Scientist: Science is Humanity's Lifeline

Pirofski, L. A., Jan 1 2017, In : Journal of Infectious Diseases. 216, p. S611-S612

Research output: Contribution to journalArticle

2016

A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection

Parameswarappa, S. G., Reppe, K., Geissner, A., Ménová, P., Govindan, S., Calow, A. D. J., Wahlbrink, A., Weishaupt, M. W., Monnanda, B. P., Bell, R. L., Pirofski, L. A., Suttorp, N., Sander, L. E., Witzenrath, M., Pereira, C. L., Anish, C. & Seeberger, P. H., Nov 17 2016, In : Cell Chemical Biology. 23, 11, p. 1407-1416 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Protease inhibitors do not affect antibody responses to pneumococcal vaccination

De La Rosa, I., Munjal, I. M., Rodriguez-Barradas, M., Yu, X., Pirofski, L. & Mendoza, D., Jun 1 2016, In : Clinical and Vaccine Immunology. 23, 6, p. 524-529 6 p.

Research output: Contribution to journalArticle

Reduction of Streptococcus pneumoniae colonization and dissemination by a nonopsonic capsular polysaccharide antibody

Doyle, C. R. & Pirofski, L. A., Feb 2 2016, In : mBio. 7, 1, e02260-15.

Research output: Contribution to journalArticle

10 Scopus citations
2015

Host immunity to Cryptococcus neoformans

Rohatgi, S. & Pirofski, L. A., Apr 1 2015, In : Future Microbiology. 10, 4, p. 565-581 17 p.

Research output: Contribution to journalReview article

45 Scopus citations

Quantitative and qualitative antibody responses to immunization with the pneumococcal polysaccharide vaccine in HIV-infected patients after initiation of antiretroviral treatment: Results from a randomized clinical trial

Rodriguez-Barradas, M. C., Serpa, J. A., Munjal, I., Mendoza, D., Rueda, A. M., Mushtaq, M. & Pirofski, L. A., Jun 1 2015, In : Journal of Infectious Diseases. 211, 11, p. 1703-1711 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

The Ebola Epidemic Crystallizes the Potential of Passive Antibody Therapy for Infectious Diseases

Casadevall, A. & Pirofski, L. A., Apr 1 2015, In : PLoS pathogens. 11, 4, e1004717.

Research output: Contribution to journalReview article

18 Scopus citations

What is a host? Incorporating the microbiota into the damage-response framework

Casadevall, A. & Pirofski, L. A., Jan 1 2015, In : Infection and Immunity. 83, 1, p. 2-7 6 p.

Research output: Contribution to journalShort survey

54 Scopus citations

What is infectiveness and how is it involved in infection and immunity?

Pirofski, L. A. & Casadevall, A., Mar 26 2015, In : BMC Immunology. 16, 1, 13.

Research output: Contribution to journalReview article

12 Scopus citations
2014

An ahemolytic pneumolysin of streptococcus pneumoniae manipulates human innate and CD4+ T-cell responses and reduces resistance to colonization in mice in a serotype-independent manner

Nadeem Khan, M., Coleman, J. R., Vernatter, J., Varshney, A. K., Dufaud, C. & Pirofski, L. A., Nov 15 2014, In : Journal of Infectious Diseases. 210, 10, p. 1658-1669 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae

Olaya-Abril, A., Prados-Rosales, R., McConnell, M. J., Martín-Peña, R., González-Reyes, J. A., Jiménez-Munguía, I., Gómez-Gascón, L., Fernández, J., Luque-García, J. L., García-Lidón, C., Estévez, H., Pachón, J., Obando, I., Casadevall, A., Pirofski, L. A. & Rodríguez-Ortega, M. J., Jun 25 2014, In : Journal of Proteomics. 106, p. 46-60 15 p.

Research output: Contribution to journalArticle

74 Scopus citations

Ditch the term pathogen

Casadevall, A. & Pirofski, L. A., Dec 11 2014, In : Nature. 516, 7530, p. 165-166 2 p.

Research output: Contribution to journalComment/debate

54 Scopus citations
2013

Current concepts in host-microbe interaction leading to pneumococcal pneumonia

Vernatter, J. & Pirofski, L. A., Jun 1 2013, In : Current Opinion in Infectious Diseases. 26, 3, p. 277-283 7 p.

Research output: Contribution to journalReview article

38 Scopus citations

Exserohilum rostratum fungal meningitis associated with methylprednisolone injections

Casadevall, A. & Pirofski, L. A., Feb 1 2013, In : Future Microbiology. 8, 2, p. 135-137 3 p.

Research output: Contribution to journalReview article

18 Scopus citations

Fc gamma receptor 3A polymorphism and risk for HIV-associated cryptococcal disease

Rohatgi, S., Gohil, S., Kuniholm, M. H., Schultz, H., Dufaud, C., Armour, K. L., Badri, S., Mailliard, R. B. & Pirofski, L. A., Aug 27 2013, In : mBio. 4, 5, e00573-13.

Research output: Contribution to journalArticle

39 Scopus citations

X-linked immunodeficient mice exhibit enhanced susceptibility to Cryptococcus neoformans infection

Szymczak, W. A., Davis, M. J., Lundy, S. K., Dufaud, C., Olszewski, M. & Pirofski, L. A., Jul 2 2013, In : mBio. 4, 4

Research output: Contribution to journalArticle

50 Scopus citations
2012

A new synthesis for antibody-mediated immunity

Casadevall, A. & Pirofski, L. A., Jan 1 2012, In : Nature Immunology. 13, 1, p. 21-28 8 p.

Research output: Contribution to journalReview article

82 Scopus citations
20 Scopus citations

CD8 + T cells and risk for bacterial pneumonia and all-cause mortality among HIV-infected women

Gohil, S. K., Heo, M., Schoenbaum, E. E., Celentano, D. & Pirofski, L. A., Jun 1 2012, In : Journal of Acquired Immune Deficiency Syndromes. 60, 2, p. 191-198 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Cryptococcus gattii infection in healthy hosts: A sentinel for subclinical immunodeficiency?

Marr, K. A., Datta, K., Pirofski, L. A. & Barnes, R., Jan 1 2012, In : Clinical Infectious Diseases. 54, 1, p. 153-154 2 p.

Research output: Contribution to journalLetter

19 Scopus citations

IL-23 dampens the allergic response to Cryptococcus neoformans through IL-17-independent and - Dependent mechanisms

Szymczak, W. A., Sellers, R. S. & Pirofski, L. A., Apr 1 2012, In : American Journal of Pathology. 180, 4, p. 1547-1559 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Immunoglobulins in defense, pathogenesis, and therapy of fungal diseases

Casadevall, A. & Pirofski, L. A., May 17 2012, In : Cell Host and Microbe. 11, 5, p. 447-456 10 p.

Research output: Contribution to journalReview article

82 Scopus citations

Molecular characterization of the early B cell response to pulmonary Cryptococcus neoformans infection

Rohatgi, S. & Pirofski, L. A., Dec 15 2012, In : Journal of Immunology. 189, 12, p. 5820-5830 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Q and A What is a pathogen? A question that begs the point

Pirofski, L. A. & Casadevall, A., Jan 31 2012, In : BMC Biology. 10, 6.

Research output: Contribution to journalComment/debate

55 Scopus citations

Tissue-expressed B7x affects the immune response to and outcome of lethal pulmonary infection

Hofmeyer, K. A., Scandiuzzi, L., Ghosh, K., Pirofski, L. A. & Zang, X., Sep 15 2012, In : Journal of Immunology. 189, 6, p. 3054-3063 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
2011

Antibodies to streptococcus pneumoniae capsular polysaccharide enhance pneumococcal quorum sensing

Yano, M., Gohil, S., Coleman, J. R., Manix, C. & Pirofski, L. A., Sep 1 2011, In : mBio. 2, 5

Research output: Contribution to journalArticle

25 Scopus citations

CD8+ cells enhance resistance to pulmonary serotype 3 Streptococcus pneumoniae infection in mice

Weber, S. E., Tian, H. & Pirofski, L. A., Jan 1 2011, In : Journal of Immunology. 186, 1, p. 432-442 11 p.

Research output: Contribution to journalArticle

50 Scopus citations
8 Scopus citations

Designed reduction of Streptococcus pneumoniae pathogenicity via synthetic changes in virulence factor codon-pair bias

Coleman, J. R., Papamichail, D., Yano, M., Del Mar García-Suárez, M. & Pirofski, L. A., May 1 2011, In : Journal of Infectious Diseases. 203, 9, p. 1264-1273 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Microbial virulence as an emergent property: Consequences and opportunities

Casadevall, A., Fang, F. C. & Pirofski, L. A., Jul 1 2011, In : PLoS pathogens. 7, 7, e1002136.

Research output: Contribution to journalArticle

52 Scopus citations