• 1052 Citations
  • 11 h-Index
20042019
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Publications 2004 2019

  • 1052 Citations
  • 11 h-Index
  • 16 Article
  • 2 Review article
2019
1 Citation (Scopus)
Autophagy
Sirolimus
Lysosomes
Lung Neoplasms
Cell Proliferation
2 Citations (Scopus)

Mechanisms of soft and hard electrophile toxicities

LoPachin, R. M., Geohagen, B. C. & Nordstroem, L. R., Apr 15 2019, In : Toxicology. 418, p. 62-69 8 p.

Research output: Contribution to journalReview article

Nucleophiles
Toxicology
Toxicity
Organic Chemistry
Electrons
2018
12 Citations (Scopus)

Inhibition of Delta-induced Notch signaling using fucose analogs

Schneider, M., Vivek, K., Nordstroem, L. R., Feng, L., Takeuchi, H., Hao, H., Luca, V. C., Garcia, K. C., Stanley, P., Wu, P. & Haltiwanger, R. S., Jan 1 2018, In : Nature Chemical Biology. 14, 1, p. 65-71 7 p.

Research output: Contribution to journalArticle

Fucose
Epidermal Growth Factor
Ligands
Cell Surface Receptors
Mutagenesis
1 Citation (Scopus)

Phloretin cytoprotection and toxicity

Geohagen, B. C., Korsharskyy, B., Vydyanatha, A., Nordstroem, L. R. & LoPachin, R. M., Dec 25 2018, In : Chemico-Biological Interactions. 296, p. 117-123 7 p.

Research output: Contribution to journalArticle

Phloretin
Cytoprotection
Toxicity
Acetaminophen
Poisons

Synthesis of stable azide and alkyne functionalized phosphoramidite nucleosides

Lingala, S., Nordstroem, L. R. & Mallikaratchy, P. R., Jan 1 2018, (Accepted/In press) In : Tetrahedron Letters.

Research output: Contribution to journalArticle

Alkynes
Azides
Nucleosides
Oligonucleotides
Thymidine
2016
3 Citations (Scopus)

Enolate-Forming Compounds as a Novel Approach to Cytoprotection

LoPachin, R. M., Geohagen, B. C., Nordstroem, L. R. & Gavin, T., Dec 19 2016, In : Chemical Research in Toxicology. 29, 12, p. 2096-2107 12 p.

Research output: Contribution to journalReview article

Cytoprotection
Poisons
Phloretin
Tacrine
Curcumin
2015
11 Citations (Scopus)

Discovery of autophagy inhibitors with antiproliferative activity in lung and pancreatic cancer cells

Nordstroem, L. R., Sironi, J., Aranda, E., Maisonet, J., Perez-Soler, R., Wu, P. & Schwartz, E. L., Feb 12 2015, In : ACS Medicinal Chemistry Letters. 6, 2, p. 134-139 6 p.

Research output: Contribution to journalArticle

Autophagy
Chloroquine
Pancreatic Neoplasms
Hydroxychloroquine
Lung Neoplasms
2013
6 Citations (Scopus)

A self-assembling short oligonucleotide duplex suitable for pretargeting

Mallikaratchy, P., Gardner, J., Nordstroem, L. R., Veomett, N. J., McDevitt, M. R., Heaney, M. L. & Scheinberg, D. A., Aug 1 2013, In : Nucleic Acid Therapeutics. 23, 4, p. 289-299 11 p.

Research output: Contribution to journalArticle

Oligonucleotides
RNA
Monoclonal Antibodies
Molecules
Pharmacokinetics
28 Citations (Scopus)

Chemical probing of glycans in cells and organisms

Rouhanifard, S. H., Nordstroem, L. R., Zheng, T. & Wu, P., May 21 2013, In : Chemical Society Reviews. 42, 10, p. 4284-4296 13 p.

Research output: Contribution to journalArticle

Polysaccharides
Molecular biology
Biosynthesis
Nucleic Acids
Proteins
46 Citations (Scopus)

Total synthesis, relay synthesis, and structural confirmation of the C18-norditerpenoid alkaloid neofinaconitine

Shi, Y., Wilmot, J. T., Nordstroem, L. R., Tan, D. S. & Gin, D. Y., Sep 25 2013, In : Journal of the American Chemical Society. 135, 38, p. 14313-14320 8 p.

Research output: Contribution to journalArticle

Alkaloids
Diterpenes
Aconitine
Cycloaddition Reaction
Cycloaddition
2012
22 Citations (Scopus)

Iridium-catalyzed condensation of amines and vicinal diols to substituted piperazines

Lorentz-Petersen, L. L. R., Nordstroem, L. R. & Madsen, R., Dec 2012, In : European Journal of Organic Chemistry. 34, p. 6752-6759 8 p.

Research output: Contribution to journalArticle

Piperazines
Iridium
Imines
iridium
imines
2010

Amide synthesis from alcohols and amines by the extrusion of dihydrogen

Nordstroem, L. R., Vogt, H. & Madsen, R., May 2010, In : Chemtracts. 23, 3, p. 90-93 4 p.

Research output: Contribution to journalArticle

Amides
Amines
Extrusion
Alcohols
phosphine
136 Citations (Scopus)

Amide synthesis from alcohols and amines catalyzed by ruthenium N-Heterocyclic carbene complexes

Dam, J. H., Osztrovszky, G., Nordstroem, L. R. & Madsen, R., Jun 18 2010, In : Chemistry - A European Journal. 16, 23, p. 6820-6827 8 p.

Research output: Contribution to journalArticle

Ruthenium
Amides
Amines
Alcohols
Catalysts
2008
385 Citations (Scopus)

Amide synthesis from alcohols and amines by the extrusion of dihydrogen

Nordstroem, L. R., Vogt, H. & Madsen, R., Dec 31 2008, In : Journal of the American Chemical Society. 130, 52, p. 17672-17673 2 p.

Research output: Contribution to journalArticle

Amides
Amines
Extrusion
phosphine
Alcohols
2007
73 Citations (Scopus)

Iridium catalysed synthesis of piperazines from diols

Nordstroem, L. R. & Madsen, R., 2007, In : Chemical Communications. 47, p. 5034-5036 3 p.

Research output: Contribution to journalArticle

Piperazines
Iridium
Amines
Atoms
115 Citations (Scopus)

"Super armed" glycosyl donors: Conformational arming of thioglycosides by silylation

Pedersen, C. M., Nordstroem, L. R. & Bols, M., Jul 25 2007, In : Journal of the American Chemical Society. 129, 29, p. 9222-9235 14 p.

Research output: Contribution to journalArticle

Thioglucosides
Thioglycosides
Disaccharides
2005
40 Citations (Scopus)

Artificial glycosyl phosphorylases

Rousseau, C., Ortega-Caballero, F., Nordstroem, L. R., Christensen, B., Petersen, T. E. & Bols, M., Aug 19 2005, In : Chemistry - A European Journal. 11, 17, p. 5094-5101 8 p.

Research output: Contribution to journalArticle

Phosphorylases
Cyclodextrins
Catalysis
Sulfates
Phosphates
2004
171 Citations (Scopus)

The disarming effect of the 4,6-acetal group on glycoside reactivity: Torsional or electronic?

Jensen, H. H., Nordstroem, L. R. & Bols, M., Aug 4 2004, In : Journal of the American Chemical Society. 126, 30, p. 9205-9213 9 p.

Research output: Contribution to journalArticle

Glycosides
Acetals
Hydrolysis
Conformations
Molecules