• 3812 Citations
  • 22 h-Index
20082019

Research output per year

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Publications

  • 3812 Citations
  • 22 h-Index
  • 35 Article
  • 4 Review article
  • 1 Comment/debate
  • 1 Editorial
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Article
2019

A major role of TWEAK/Fn14 axis as a therapeutic target for post-angioplasty restenosis

Méndez-Barbero, N., Gutierrez-Muñoz, C., Madrigal-Matute, J., Mínguez, P., Egido, J., Michel, J. B., Martín-Ventura, J. L., Esteban, V. & Blanco-Colio, L. M., Aug 2019, In : EBioMedicine. 46, p. 274-289 16 p.

Research output: Contribution to journalArticle

Open Access

Proteome-wide analysis of chaperone-mediated autophagy targeting motifs

Kirchner, P., Bourdenx, M., Madrigal-Matute, J., Tiano, S., Diaz, A., Bartholdy, B. A., Will, B. & Cuervo, A. M., May 1 2019, In : PLoS biology. 17, 5, p. e3000301

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2018

Autophagy is required for sortilin-mediated degradation of apolipoprotein B100

Amengual, J., Guo, L., Strong, A., Madrigal-Matute, J., Wang, H., Kaushik, S., Brodsky, J. L., Rader, D. J., Cuervo, A. M. & Fisher, E. A., Feb 2018, In : Circulation research. 122, 4, p. 568-582 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

Interferon-α triggers autoimmune thyroid diseases via lysosomal-dependent degradation of thyroglobulin

Faustino, L. C., Lombardi, A., Madrigal-Matute, J., Owen, R. P., Libutti, S. K. & Tomer, Y., Oct 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 10, p. 3678-3687 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

LeDUCQ network modulating autophagy to treat cardiovascular disease

Madrigal-Matute, J., Scorrano, L. & Sadoshima, J., Jan 1 2018, In : Circulation research. 123, 3, p. 323-325 3 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Nrf2 activation provides atheroprotection in diabetic mice through concerted upregulation of antioxidant, anti-inflammatory, and autophagy mechanisms

Lazaro, I., Lopez-Sanz, L., Bernal, S., Oguiza, A., Recio, C., Melgar, A., Jimenez-Castilla, L., Egido, J., Madrigal-Matute, J. & Gomez-Guerrero, C., Jan 1 2018, In : Frontiers in Pharmacology. 9, 819.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2017

Lanosterol Modulates TLR4-Mediated Innate Immune Responses in Macrophages

Araldi, E., Fernández-Fuertes, M., Canfrán-Duque, A., Tang, W., Cline, G. W., Madrigal-Matute, J., Pober, J. S., Lasunción, M. A., Wu, D., Fernández-Hernando, C. & Suárez, Y., Jun 27 2017, In : Cell Reports. 19, 13, p. 2743-2755 13 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
2016

ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression

Aryal, B., Rotllan, N., Araldi, E., Ramírez, C. M., He, S., Chousterman, B. G., Fenn, A. M., Wanschel, A., Madrigal-Matute, J., Warrier, N., Martín-Ventura, J. L., Swirski, F. K., Suárez, Y. & Fernández-Hernando, C., Jul 27 2016, In : Nature communications. 7, 12313.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

Mitchell, S. J., Madrigal-Matute, J., Scheibye-Knudsen, M., Fang, E., Aon, M., González-Reyes, J. A., Cortassa, S., Kaushik, S., Gonzalez-Freire, M., Patel, B., Wahl, D., Ali, A., Calvo-Rubio, M., Burón, M. I., Guiterrez, V., Ward, T. M., Palacios, H. H., Cai, H., Frederick, D. W., Hine, C. & 27 others, Broeskamp, F., Habering, L., Dawson, J., Beasley, T. M., Wan, J., Ikeno, Y., Hubbard, G., Becker, K. G., Zhang, Y., Bohr, V. A., Longo, D. L., Navas, P., Ferrucci, L., Sinclair, D. A., Cohen, P., Egan, J. M., Mitchell, J. R., Baur, J. A., Allison, D. B., Anson, R. M., Villalba, J. M., Madeo, F., Cuervo, A. M., Pearson, K. J., Ingram, D. K., Bernier, M. & De Cabo, R., Jun 14 2016, In : Cell metabolism. 23, 6, p. 1093-1112 20 p.

Research output: Contribution to journalArticle

133 Scopus citations

Regulation of Liver Metabolism by Autophagy

Madrigal-Matute, J. & Cuervo, A. M., Feb 1 2016, In : Gastroenterology. 150, 2, p. 328-339 12 p.

Research output: Contribution to journalArticle

117 Scopus citations
2015

Targeting HSP90 ameliorates nephropathy and atherosclerosis through suppression of NF-κB and STAT signaling pathways in diabetic mice

Lazaro, I., Oguiza, A., Recio, C., Mallavia, B., Madrigal-Matute, J., Blanco, J., Egido, J., Martin-Ventura, J. L. & Gomez-Guerrero, C., Oct 2015, In : Diabetes. 64, 10, p. 3600-3613 14 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Thioredoxin-1/peroxiredoxin-1 as sensors of oxidative stress mediated by NADPH oxidase activity in atherosclerosis

Madrigal-Matute, J., Fernandez-Garcia, C. E., Blanco-Colio, L. M., Burillo, E., Fortuño, A., Martinez-Pinna, R., Llamas-Granda, P., Beloqui, O., Egido, J., Zalba, G. & Martin-Ventura, J. L., Jul 25 2015, In : Free Radical Biology and Medicine. 86, p. 352-361 10 p., 12461.

Research output: Contribution to journalArticle

15 Scopus citations

TWEAK/Fn14 interaction promotes oxidative stress through NADPH oxidase activation in macrophages

Madrigal-Matute, J., Fernandez-Laso, V., Sastre, C., Llamas-Granda, P., Egido, J., Martin-Ventura, J. L., Zalba, G. & Blanco-Colio, L. M., May 21 2015, In : Cardiovascular research. 108, 1, p. 139-147 9 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations
2014

From tissue iron retention to low systemic haemoglobin levels, new pathophysiological biomarkers of human abdominal aortic aneurysm

Martinez-Pinna, R., Lindholt, J. S., Madrigal-Matute, J., Blanco-Colio, L. M., Esteban-Salan, M., Torres-Fonseca, M. M., Lefebvre, T., Delbosc, S., Laustsen, J., Driss, F., de Ceniga, M. V., Gouya, L., Weiss, G., Egido, J., Meilhac, O., Michel, J. B. & Martin-Ventura, J. L., 2014, In : Thrombosis and Haemostasis. 112, 1, p. 87-95 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Galectin-3, a biomarker linking oxidative stress and inflammation with the clinical outcomes of patients with atherothrombosis

Madrigal-Matute, J., Lindholt, J. S., Fernandez-Garcia, C. E., Benito-Martin, A., Burillo, E., Zalba, G., Beloqui, O., Llamas-Granda, P., Ortiz, A., Egido, J., Blanco-Colio, L. M. & Martin-Ventura, J. L., Jan 1 2014, In : Journal of the American Heart Association. 3, 4, e000785.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations

Genetic deletion or TWEAK blocking antibody administration reduce atherosclerosis and enhance plaque stability in mice

Sastre, C., Fernández-Laso, V., Madrigal-Matute, J., Muñoz-García, B., Moreno, J. A., Pastor-Vargas, C., Llamas-Granda, P., Burkly, L. C., Egido, J., Martín-Ventura, J. L. & Blanco-Colio, L. M., Apr 2014, In : Journal of Cellular and Molecular Medicine. 18, 4, p. 721-734 14 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Label-free proteomic analysis of red blood cell membrane fractions from abdominal aortic aneurysm patients

Martinez-Pinna, R., Burillo, E., Madrigal-Matute, J., Lopez, J. A., Camafeita, E., Torres-Fonseca, M. M., Llamas-Granda, P., Egido, J., Michel, J. B., Blanco-Colio, L. M. & Martin-Ventura, J. L., Aug 2014, In : Proteomics - Clinical Applications. 8, 7-8, p. 626-630 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

RNA binding protein HuR regulates the expression of ABCA1

Ramírez, C. M., Lin, C. S., Abdelmohsen, K., Goedeke, L., Yoon, J. H., Madrigal-Matute, J., Martin-Ventura, J. L., Vo, D. T., Uren, P. J., Penalva, L. O., Gorospe, M. & Fernández-Hernando, C., Jun 2014, In : Journal of Lipid Research. 55, 6, p. 1066-1076 11 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Tumor necrosis factor-like weak inducer of apoptosis or Fn14 deficiency reduce elastase perfusion-induced aortic abdominal aneurysm in mice

Tarín, C., Ferńandez-Laso, V., Sastre, C., Madrigal-Matute, J., Gómez, M., Zaragoza, C., Egido, J., Burkly, L. C., Martín-Ventura, J. L. & Blanco-Colio, L. M., Jan 1 2014, In : Journal of the American Heart Association. 3, 4, e000723.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
2013

HMGB1 expression and secretion are increased via TWEAK-Fn14 interaction in atherosclerotic plaques and cultured monocytes

Moreno, J. A., Sastre, C., Madrigal-Matute, J., Muñoz-García, B., Ortega, L., Burkly, L. C., Egido, J., Martín-Ventura, J. L. & Blanco-Colio, L. M., Mar 1 2013, In : Arteriosclerosis, thrombosis, and vascular biology. 33, 3, p. 612-620 9 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Proteomic analysis of intraluminal thrombus highlights complement activation in human abdominal aortic aneurysms

Martinez-Pinna, R., Madrigal-Matute, J., Tarin, C., Burillo, E., Esteban-Salan, M., Pastor-Vargas, C., Lindholt, J. S., Lopez, J. A., Calvo, E., De Ceniga, M. V., Meilhac, O., Egido, J., Blanco-Colio, L. M., Michel, J. B. & Martin-Ventura, J. L., Aug 1 2013, In : Arteriosclerosis, thrombosis, and vascular biology. 33, 8, p. 2013-2020 8 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations
2012

Erythrocytes, leukocytes and platelets as a source of oxidative stress in chronic vascular diseases: Detoxifying mechanisms and potential therapeutic options

Martin-Ventura, J. L., Madrigal-Matute, J., Martinez-Pinna, R., Ramos-Mozo, P., Blanco-Colio, L. M., Moreno, J. A., Tarin, C., Burillo, E., Fernandez-Garcia, C. E., Egido, J., Meilhac, O. & Michel, J. B., Sep 1 2012, In : Thrombosis and Haemostasis. 108, 3, p. 435-442 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

HSP90 inhibition by 17-DMAG attenuates oxidative stress in experimental atherosclerosis

Madrigal-Matute, J., Fernandez-Garcia, C. E., Gomez-Guerrero, C., Lopez-Franco, O., Muñoz-Garcia, B., Egido, J., Blanco-Colio, L. M. & Martin-Ventura, J. L., Jul 1 2012, In : Cardiovascular research. 95, 1, p. 116-123 8 p.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations

Increased plasma levels of NGAL, a marker of neutrophil activation, in patients with abdominal aortic aneurysm

Ramos-Mozo, P., Madrigal-Matute, J., Vega de Ceniga, M., Blanco-Colio, L. M., Meilhac, O., Feldman, L., Michel, J. B., Clancy, P., Golledge, J., Norman, P. E., Egido, J. & Martin-Ventura, J. L., Feb 1 2012, In : Atherosclerosis. 220, 2, p. 552-556 5 p.

Research output: Contribution to journalArticle

35 Scopus citations
2011

Heat-shock proteins in cardiovascular disease

Madrigal-Matute, J., Martin-Ventura, J. L., Blanco-Colio, L. M., Egido, J., Michel, J. B. & Meilhac, O., Apr 18 2011, In : Advances in Clinical Chemistry. 54, p. 1-43 43 p.

Research output: Contribution to journalArticle

24 Scopus citations

Identification of peroxiredoxin-1 as a novel biomarker of abdominal aortic aneurysm

Martinez-Pinna, R., Ramos-Mozo, P., Madrigal-Matute, J., Blanco-Colio, L. M., Lopez, J. A., Calvo, E., Camafeita, E., Lindholt, J. S., Meilhac, O., Delbosc, S., Michel, J. B., De Ceniga, M. V., Egido, J. & Martin-Ventura, J. L., Apr 1 2011, In : Arteriosclerosis, thrombosis, and vascular biology. 31, 4, p. 935-943 9 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations

Proteomic analysis of polymorphonuclear neutrophils identifies catalase as a novel biomarker of abdominal aortic aneurysm: Potential implication of oxidative stress in abdominal aortic aneurysm progression

Ramos-Mozo, P., Madrigal-Matute, J., Martinez-Pinna, R., Blanco-Colio, L. M., Lopez, J. A., Camafeita, E., Meilhac, O., Michel, J. B., Aparicio, C., De Ceniga, M. V., Egido, J. & Martín-Ventura, J. L., Dec 1 2011, In : Arteriosclerosis, thrombosis, and vascular biology. 31, 12, p. 3011-3019 9 p.

Research output: Contribution to journalArticle

Open Access
53 Scopus citations

TWEAKFn14 interaction enhances plasminogen activator inhibitor 1 and tissue factor expression in atherosclerotic plaques and in cultured vascular smooth muscle cells

Muñoz-Garca, B., Madrigal-Matute, J., Moreno, J. A., Martin-Ventura, J. L., López-Franco, O., Sastre, C., Ortega, L., Burkly, L. C., Egido, J. & Blanco-Colio, L. M., Jan 1 2011, In : Cardiovascular research. 89, 1, p. 225-233 9 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations
2010

Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis

Madrigal-Matute, J., López-Franco, O., Blanco-Colio, L. M., Muñoz-García, B., Ramos-Mozo, P., Ortega, L., Egido, J. & Martín-Ventura, J. L., May 1 2010, In : Cardiovascular research. 86, 2, p. 330-337 8 p.

Research output: Contribution to journalArticle

Open Access
83 Scopus citations

Increased levels of thioredoxin in patients with abdominal aortic aneurysms (AAAs). A potential link of oxidative stress with AAA evolution

Martinez-Pinna, R., Lindholt, J. S., Blanco-Colio, L. M., Dejouvencel, T., Madrigal-Matute, J., Ramos-Mozo, P., Vega de Ceniga, M., Michel, J. B., Egido, J., Meilhac, O. & Martin-Ventura, J. L., Sep 1 2010, In : Atherosclerosis. 212, 1, p. 333-338 6 p.

Research output: Contribution to journalArticle

30 Scopus citations
2009

Biomarcadores en la medicina cardiovascular

Translated title of the contribution: Biomarkers in Cardiovascular MedicineMartín-Ventura, J. L., Blanco-Colio, L. M., Tuñón, J., Muñoz-García, B., Madrigal-Matute, J., Moreno, J. A., Vega De Céniga, M. & Egido, J., Jun 2009, In : Revista Espanola de Cardiologia. 62, 6, p. 677-688 12 p.

Research output: Contribution to journalArticle

46 Scopus citations

Increased CD74 expression in human atherosclerotic plaques: Contribution to inflammatory responses in vascular cells

Martín-Ventura, J. L., Madrigal-Matute, J., Muñoz-Garcia, B., Blanco-Colio, L. M., Van Oostrom, M., Zalba, G., Fortuño, A., Gomez-Guerrero, C., Ortega, L., Ortiz, A., Diez, J. & Egido, J., Aug 1 2009, In : Cardiovascular research. 83, 3, p. 586-594 9 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Las proteínas de choque térmico (heat shock proteins) como potenciales dianas terapéuticas en aterosclerosis

Translated title of the contribution: Heat shock proteins as potential therapeutic targets in atherosclerosisMadrigal-Matute, J., López-Franco, Ó., Blanco-Colio, L. M., Muñoz-García, B., Ramos-Mozo, P., Oostrom, M. V., Meilhac, O., Michel, J. B., Egido, J. & Martín Ventura, J. L., Aug 1 2009, In : Clinica e Investigacion en Arteriosclerosis. 21, 4, p. 163-172 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

The CD163-expressing macrophages recognize and internalize TWEAK. Potential consequences in atherosclerosis

Moreno, J. A., Muñoz-García, B., Martín-Ventura, J. L., Madrigal-Matute, J., Orbe, J., Páramo, J. A., Ortega, L., Egido, J. & Blanco-Colio, L. M., Nov 1 2009, In : Atherosclerosis. 207, 1, p. 103-110 8 p.

Research output: Contribution to journalArticle

98 Scopus citations
2008

Treatment with amlodipine and atorvastatin has additive effect on blood and plaque inflammation in hypertensive patients with carotid atherosclerosis

Martín-Ventura, J. L., Mũoz-Garcia, B., Blanco-Colio, L. M., Martín-Conejero, A., Madrigal-Matute, J., Vega, M., Ortega, L., Serrano, J. & Egido, J., Dec 2008, In : Kidney international. 74, SUPPL. 111, p. S71-S74

Research output: Contribution to journalArticle

Open Access
19 Scopus citations