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John S. Blanchard, Ph.D.

  • 9349 Citations
  • 53 h-Index
1980 …2019
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  • 2 Similar Profiles
Mycobacterium tuberculosis Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Kinetics Chemical Compounds
Isotopes Chemical Compounds
NAD Medicine & Life Sciences
Substrates Chemical Compounds
Acetyltransferases Chemical Compounds
NADP Chemical Compounds

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Grants 1984 2019

MECHANISMS OF AMINOGLYCOSIDE RESISTANCE

Blanchard, J. S.

National Institutes of Health

3/16/01 → …

Project: Research project

Aminoglycosides
Anti-Bacterial Agents
Biological Products
Gram-Negative Bacterial Infections
Genes

Bacterial N-Acetyltransferases: Resistance to Regulation

Blanchard, J. S.

National Institutes of Health

5/1/04 → 4/30/19

Project: Research project

Acetyltransferases
Proteins
Acetylation
Mycobacterium tuberculosis
Aminoglycosides

ENZYMES,COENZYMES &METABOLIC PATHWAYS GORDON CONFERENCE

Blanchard, J. S.

National Institutes of Health

7/1/98 → 6/30/99

Project: Research project

coenzymes
biochemical pathways
enzymology
enzymes
canes

MECHANISM BASED INHIBITION OF M TUBERCULOSIS ENZYMES

Blanchard, J. S.

National Institutes of Health

9/30/92 → 2/28/14

Project: Research project

Tuberculosis
Enzymes
Biosynthetic Pathways
Mycobacterium tuberculosis
Anti-Bacterial Agents

MECHANISM OF FLAVOPROTEIN REDUCTASES

Blanchard, J. S.

National Institutes of Health

4/1/84 → 1/31/06

Project: Research project

Flavoproteins
Oxidoreductases
NAD+ peroxidase
Glutathione Reductase
Enzymes

Publications 1980 2018

  • 9349 Citations
  • 53 h-Index
  • 215 Article
  • 2 Chapter
  • 1 Review article

Biochemical Characterization of the Mycobacterium smegmatis Threonine Deaminase

Favrot, L., Amorim Franco, T. M. & Blanchard, J. S., Oct 16 2018, In : Biochemistry. 57, 41, p. 6003-6012 10 p.

Research output: Contribution to journal › Article

Threonine Dehydratase
Mycobacterium smegmatis
Isoleucine
Biosynthesis
Valine
10 Citations (Scopus)

Bacterial Branched-Chain Amino Acid Biosynthesis: Structures, Mechanisms, and Drugability

Amorim Franco, T. M. & Blanchard, J. S., Nov 7 2017, In : Biochemistry. 56, 44, p. 5849-5865 17 p.

Research output: Contribution to journal › Review article

Branched Chain Amino Acids
Biosynthesis
Bacterial Drug Resistance
Isoleucine
Valine
7 Citations (Scopus)

Identification of mycobacterial RplJ/L10 and RpsA/S1 proteins as novel targets for CD4+ T cells

Johnson, A. J., Kennedy, S. C., Arlehamn, C. S. L., Goldberg, M. F., Saini, N. K., Xu, J., Paul, S., Hegde, S., Blanchard, J. S., Chan, J., Jacobs, W. R., Sette, A. & Porcelli, S. A., Apr 1 2017, In : Infection and Immunity. 85, 4, e01023-16.

Research output: Contribution to journal › Article

T-Lymphocytes
Ribosomes
Mycobacterium tuberculosis
Tuberculosis Vaccines
Proteins
8 Citations (Scopus)

Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d - And l -Cycloserine

Amorim Franco, T. M., Favrot, L., Vergnolle, O. M. & Blanchard, J. S., May 19 2017, In : ACS Chemical Biology. 12, 5, p. 1235-1244 10 p.

Research output: Contribution to journal › Article

Cycloserine
Mycobacterium tuberculosis
Multidrug-Resistant Tuberculosis
branched-chain-amino-acid transaminase
Pyridoxal Phosphate
1 Citation (Scopus)

Mechanistic Characterization of Escherichia coli l -Aspartate Oxidase from Kinetic Isotope Effects

Chow, C., Hegde, S. & Blanchard, J. S., Aug 8 2017, In : Biochemistry. 56, 31, p. 4044-4052 9 p.

Research output: Contribution to journal › Article

Aspartic Acid
Isotopes
Escherichia coli
Oxidoreductases
Succinate Dehydrogenase