Projects per year
Fingerprint Dive into the research topics where John S. Blanchard is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Mycobacterium tuberculosis
Medicine & Life Sciences
Enzymes
Medicine & Life Sciences
Kinetics
Chemical Compounds
Isotopes
Chemical Compounds
NAD
Medicine & Life Sciences
Substrates
Chemical Compounds
Acetyltransferases
Chemical Compounds
NADP
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 1984 2019
Aminoglycosides
Anti-Bacterial Agents
Biological Products
Gram-Negative Bacterial Infections
Genes
Acetyltransferases
Proteins
Acetylation
Mycobacterium tuberculosis
Aminoglycosides
coenzymes
biochemical pathways
enzymology
enzymes
canes
Tuberculosis
Enzymes
Biosynthetic Pathways
Mycobacterium tuberculosis
Anti-Bacterial Agents
Flavoproteins
Oxidoreductases
NAD+ peroxidase
Glutathione Reductase
Enzymes
Publications 1980 2019
The active site of the Mycobacterium tuberculosis branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster
Bashiri, G., Grove, T. L., Hegde, S., Lagautriere, T., Gerfen, G. J., Almo, S. C., Squire, C. J., Blanchard, J. S. & Baker, E. N., Jan 1 2019, In : Journal of Biological Chemistry. 294, 35, p. 13158-13170 13 p.Research output: Contribution to journal › Article
dihydroxyacid dehydratase
Branched Chain Amino Acids
Biosynthesis
Mycobacterium tuberculosis
Catalytic Domain
Biochemical Characterization of the Mycobacterium smegmatis Threonine Deaminase
Favrot, L., Amorim Franco, T. M. & Blanchard, J. S., Oct 16 2018, In : Biochemistry. 57, 41, p. 6003-6012 10 p.Research output: Contribution to journal › Article
Threonine Dehydratase
Mycobacterium smegmatis
Isoleucine
Biosynthesis
Valine
16
Citations
(Scopus)
Bacterial Branched-Chain Amino Acid Biosynthesis: Structures, Mechanisms, and Drugability
Amorim Franco, T. M. & Blanchard, J. S., Nov 7 2017, In : Biochemistry. 56, 44, p. 5849-5865 17 p.Research output: Contribution to journal › Review article
Branched Chain Amino Acids
Biosynthesis
Bacterial Drug Resistance
Isoleucine
Valine
9
Citations
(Scopus)
Identification of mycobacterial RplJ/L10 and RpsA/S1 proteins as novel targets for CD4+ T cells
Johnson, A. J., Kennedy, S. C., Arlehamn, C. S. L., Goldberg, M. F., Saini, N. K., Xu, J., Paul, S., Hegde, S. S., Blanchard, J. S., Chan, J., Jacobs, W. R., Sette, A. & Porcelli, S. A., Apr 1 2017, In : Infection and Immunity. 85, 4, e01023-16.Research output: Contribution to journal › Article
T-Lymphocytes
Ribosomes
Mycobacterium tuberculosis
Tuberculosis Vaccines
Proteins
10
Citations
(Scopus)
Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d - And l -Cycloserine
Amorim Franco, T. M., Favrot, L., Vergnolle, O. M. & Blanchard, J. S., May 19 2017, In : ACS Chemical Biology. 12, 5, p. 1235-1244 10 p.Research output: Contribution to journal › Article
Cycloserine
Mycobacterium tuberculosis
Multidrug-Resistant Tuberculosis
branched-chain-amino-acid transaminase
Pyridoxal Phosphate