• 13633 Citations
  • 56 h-Index
1984 …2023
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  • 18 Similar Profiles
Mycobacterium tuberculosis Medicine & Life Sciences
Tuberculosis Medicine & Life Sciences
Mycobacterium Infections Medicine & Life Sciences
Infection Medicine & Life Sciences
Mycobacterium bovis Medicine & Life Sciences
Macrophages Medicine & Life Sciences
Mycobacterium Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences

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Grants 1996 2023

Humoral immunity against the M. tuberculosis kasB persistent mutant

Chan, J.

National Institutes of Health

5/15/184/30/20

Project: Research projectExploratory/Developmental Grants

Humoral Immunity
Mycobacterium tuberculosis
Tuberculosis
Bacillus
Mycolic Acids
Indoleamine-Pyrrole 2,3,-Dioxygenase
Tuberculosis
Protein Isoforms
Immunosuppressive Agents
Mycobacterium tuberculosis

B cells and humoral immunity in tuberculosis

Chan, J.

National Institutes of Health

12/15/1111/30/17

Project: Research projectResearch Project

Humoral Immunity
Tuberculosis
B-Lymphocytes
Mycobacterium tuberculosis
T-Lymphocytes

Genetic Approaches for Improving Tuberculosis Vaccines

Porcelli, S. A., Chan, J. & Jacobs, W. R.

National Institutes of Health

10/1/046/30/17

Project: Research projectResearch Program Projects

Tuberculosis Vaccines
Mycobacterium tuberculosis
Tuberculosis
Granuloma
Vaccines

M tuberculosis truncated hemoglobins in persistence

Chan, J.

National Institutes of Health

8/1/027/31/05

Project: Research projectExploratory/Developmental Grants

Truncated Hemoglobins
Mycobacterium tuberculosis
Tuberculosis
Nitric Oxide
Mycobacterium bovis

Publications 1984 2018

  • 13633 Citations
  • 56 h-Index
  • 106 Article
  • 1 Chapter

Identification of mycobacterial ribosomal proteins as targets for CD4+ T cells that enhance protective immunity in tuberculosis

Kennedy, S. C., Johnson, A. J., Bharrhan, S., Arlehamn, C. S. L., Xu, J., Garforth, S. J., Chan, J., Jacobs, W. R., Sette, A., Almo, S. C. & Porcelli, S. A., Sep 1 2018, In : Infection and Immunity. 86, 9, e00009-18.

Research output: Contribution to journalArticle

Ribosomal Proteins
Mycobacterium tuberculosis
Mycobacterium bovis
Immunity
Tuberculosis
18 Citations

Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine

Prados-Rosales, R., Carreño, L., Cheng, T., Blanc, C., Weinrick, B., Malek, A., Lowary, T. L., Baena, A., Joe, M., Bai, Y., Kalscheuer, R., Batista-Gonzalez, A., Saavedra, N. A., Sampedro, L., Tomás, J., Anguita, J., Hung, S. C., Tripathi, A., Xu, J., Glatman-Freedman, A. & 5 othersJacobs, W. R., Chan, J., Porcelli, S. A., Achkar, J. M. & Casadevall, A., Mar 1 2017, In : PLoS Pathogens. 13, 3, e1006250.

Research output: Contribution to journalArticle

Conjugate Vaccines
Mycobacterium tuberculosis
Antibody Formation
Polysaccharides
Tuberculosis
6 Citations

Identification of mycobacterial RplJ/L10 and RpsA/S1 proteins as novel targets for CD4+ T cells

Johnson, A. J., Kennedy, S. C., Arlehamn, C. S. L., Goldberg, M. F., Saini, N. K., Xu, J., Paul, S., Hegde, S. S., Blanchard, J. S., Chan, J., Jacobs, W. R., Sette, A. & Porcelli, S. A., Apr 1 2017, In : Infection and Immunity. 85, 4, e01023-16.

Research output: Contribution to journalArticle

T-Lymphocytes
Ribosomes
Mycobacterium tuberculosis
Tuberculosis Vaccines
Proteins
1 Citations

Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (APC) transporter Rv1747 to regulate mycobacterial growth

Glass, L. N., Swapna, G., Chavadi, S. S., Tufariello, J. A. M., Mi, K., Drumm, J. E., Lam, T. K. T., Zhu, G., Zhan, C., Vilchéze, C., Arcos, J., Chen, Y., Bi, L., Mehta, S., Porcelli, S. A., Almo, S. C., Yeh, S. R., Jacobs, W. R., Torrelles, J. B. & Chan, J., Jul 1 2017, In : PLoS Pathogens. 13, 7, e1006515.

Research output: Contribution to journalArticle

ATP-Binding Cassette Transporters
Heat-Shock Proteins
Mycobacterium tuberculosis
Growth
Threonine
1 Citations

Transcriptome analysis of mycobacteria-specific CD4+ T cells identified by activation-induced expression of CD154

Kunnath-Velayudhan, S., Goldberg, M. F., Saini, N. K., Johndrow, C. T., Ng, T. W., Johnson, A. J., Xu, J., Chan, J., Jacobs, W. R. & Porcelli, S. A., Oct 1 2017, In : Journal of Immunology. 199, 7, p. 2596-2606 11 p.

Research output: Contribution to journalArticle

Gene Expression Profiling
Mycobacterium
T-Lymphocytes
Mycobacterium bovis
Cytokines