John Chan, M.D.

Kennedy, S. C., Johnson, A. J., Bharrhan, S., Arlehamn, C. S. L., Xu, J., Garforth, S. J., Chan, J., Jacobs, W. R., Sette, A., Almo, S. C. & Porcelli, S. A., Sep 1 2018, In : Infection and Immunity. 86, 9, e00009-18.

Research output: Contribution to journal › Article

Ribosomal Proteins

Mycobacterium tuberculosis

Mycobacterium bovis

Immunity

Tuberculosis

Suppression of Th1 priming by TLR2 agonists during cutaneous immunization is mediated by recruited CCR2⁺ monocytes

Johndrow, C. T., Goldberg, M. F., Johnson, A. J., Ng, T. W., Kunnath-Velayudhan, S., Lauvau, G., Kaplan, D. H., Gossel, G. H., Kadolsky, U. D., Yates, A. J., Chan, J., Jacobs, W. R. & Porcelli, S. A., Dec 15 2018, In : Journal of Immunology. 201, 12, p. 3604-3616 13 p.

Research output: Contribution to journal › Article

Subunit Vaccines

Mycobacterium bovis

Pattern Recognition Receptors

Monocytes

Immunization

20 Citations

Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine

Prados-Rosales, R., Carreño, L., Cheng, T., Blanc, C., Weinrick, B., Malek, A., Lowary, T. L., Baena, A., Joe, M., Bai, Y., Kalscheuer, R., Batista-Gonzalez, A., Saavedra, N. A., Sampedro, L., Tomás, J., Anguita, J., Hung, S. C., Tripathi, A., Xu, J., Glatman-Freedman, A. & 5 othersJacobs, W. R., Chan, J., Porcelli, S. A., Achkar, J. M. & Casadevall, A., Mar 1 2017, In : PLoS Pathogens. 13, 3, e1006250.

Research output: Contribution to journal › Article

Conjugate Vaccines

Mycobacterium tuberculosis

Antibody Formation

Polysaccharides

Tuberculosis

7 Citations

Identification of mycobacterial RplJ/L10 and RpsA/S1 proteins as novel targets for CD4⁺ T cells

Johnson, A. J., Kennedy, S. C., Arlehamn, C. S. L., Goldberg, M. F., Saini, N. K., Xu, J., Paul, S., Hegde, S., Blanchard, J. S., Chan, J., Jacobs, W. R., Sette, A. & Porcelli, S. A., Apr 1 2017, In : Infection and Immunity. 85, 4, e01023-16.

Research output: Contribution to journal › Article

T-Lymphocytes

Ribosomes

Mycobacterium tuberculosis

Tuberculosis Vaccines

Proteins

2 Citations

Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (APC) transporter Rv1747 to regulate mycobacterial growth

Glass, L. N., Swapna, G., Chavadi, S. S., Tufariello, J. A. M., Mi, K., Drumm, J. E., Lam, T. K. T., Zhu, G., Zhan, C., Vilchéze, C., Arcos, J., Chen, Y., Bi, L., Mehta, S., Porcelli, S. A., Almo, S. C., Yeh, S-R., Jacobs, W. R., Torrelles, J. B. & Chan, J., Jul 1 2017, In : PLoS Pathogens. 13, 7, e1006515.

Research output: Contribution to journal › Article

ATP-Binding Cassette Transporters

Heat-Shock Proteins

Mycobacterium tuberculosis

Growth

Threonine