• 84 Citations
  • 3 h-Index
20162019
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Fingerprint Dive into the research topics where Jennifer S. Spence is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Ebolavirus Medicine & Life Sciences
Glycoproteins Medicine & Life Sciences
Immunization Chemical Compounds
Virion Medicine & Life Sciences
Virus Internalization Medicine & Life Sciences
Lysosomes Medicine & Life Sciences
Fusion reactions Chemical Compounds
Vaccines Chemical Compounds

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Publications 2016 2019

  • 84 Citations
  • 3 h-Index
  • 4 Article

A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry

Fels, J. M., Spence, J. S., Bortz, R. H., Bornholdt, Z. A. & Chandran, K., Jul 9 2019, In : mBio. 10, 4

Research output: Contribution to journalArticle

Open Access
Ebolavirus
Glycoproteins
Mutation
Virus Internalization
Ebola Vaccines
8 Citations (Scopus)

IFITM3 directly engages and shuttles incoming virus particles to lysosomes

Spence, J. S., He, R., Hoffmann, H. H., Das, T., Thinon, E., Rice, C. M., Peng, T., Chandran, K. & Hang, H. C., Jan 1 2019, (Accepted/In press) In : Nature Chemical Biology.

Research output: Contribution to journalArticle

Lysosomes
Virion
Lipoylation
Transport Vesicles
Virus Diseases
42 Citations (Scopus)

Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability

Zhao, X., Howell, K. A., He, S., Brannan, J. M., Wec, A. Z., Davidson, E., Turner, H. L., Chiang, C. I., Lei, L., Fels, J. M., Vu, H., Shulenin, S., Turonis, A. N., Kuehne, A. I., Liu, G., Ta, M., Wang, Y., Sundling, C., Xiao, Y., Spence, J. S. & 8 others, Doranz, B. J., Holtsberg, F. W., Ward, A. B., Chandran, K., Dye, J. M., Qiu, X., Li, Y. & Aman, M. J., May 18 2017, In : Cell. 169, 5, p. 891-904.e15

Research output: Contribution to journalArticle

Ebolavirus
Immunization
Glycoproteins
Fusion reactions
Vaccines
34 Citations (Scopus)

Direct visualization of Ebola virus fusion triggering in the endocytic pathway

Spence, J. S., Krause, T. B., Mittler, E., Jangra, R. K. & Chandran, K., Feb 9 2016, In : mBio. 7, 1, e01857-15.

Research output: Contribution to journalArticle

Ebolavirus
Glycoproteins
Virus Internalization
Cysteine Proteases
Endosomes