Projects per year
Fingerprint Dive into the research topics where I. David Goldman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 8 Similar Profiles
Folic Acid
Medicine & Life Sciences
Methotrexate
Medicine & Life Sciences
Reduced Folate Carrier Protein
Medicine & Life Sciences
Proton-Coupled Folate Transporter
Medicine & Life Sciences
Folic Acid Antagonists
Medicine & Life Sciences
Ehrlich Tumor Carcinoma
Medicine & Life Sciences
Pemetrexed
Medicine & Life Sciences
Leukemia L1210
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 1976 2019
- 8 Finished
Folic Acid Antagonists
Folic Acid
Proton-Coupled Folate Transporter
Mutation
Pemetrexed
POSTDOCTORAL TRAINING IN CANCER BIOLOGY
Goldman, I. D., Westin, E. & Grant, S.
7/1/87 → 6/30/99
Project: Research project
Membranes
Pharmaceutical Preparations
Neoplasms
Drug Resistance
Neoplastic Processes
Folic Acid Antagonists
Pharmacology
Folic Acid
Membranes
Antineoplastic Agents
MEMBRANE PHENOMENA RELEVANT TO CARDIOVASCULAR DISEASE
Goldman, I. D., Westin, E. & Dessypris, E.
7/1/80 → 6/30/98
Project: Research project
Publications 1968 2019
Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation
Aluri, S., Zhao, R., Lin, K., Shin, D. S., Fiser, A. & Goldman, I. D., Jan 1 2019, In : Journal of Biological Chemistry. 294, 18, p. 7245-7258 14 p.Research output: Contribution to journal › Article
Proton-Coupled Folate Transporter
Conformations
Substitution reactions
Cysteine
Scaffolds
Upregulation of reduced folate carrier by Vitamin D enhances brain folate uptake in mice lacking folate receptor alpha
Alam, C., Aufreiter, S., Georgiou, C. J., Hoque, M. T., Finnell, R. H., O'Connor, D. L., Goldman, I. D. & Bendayan, R., Aug 27 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17531-17540 10 p.Research output: Contribution to journal › Article
Open Access
Reduced Folate Carrier Protein
Folic Acid
Vitamin D
Up-Regulation
Brain
Concentrative transport of antifolates mediated by the proton-coupled folate transporter (slc46a1); Augmentation by a hepes buffer
Zhao, R., Najmi, M., Aluri, S., Spray, D. C. & Goldman, I. D., Mar 1 2018, In : Molecular Pharmacology. 93, 3, p. 208-215 8 p.Research output: Contribution to journal › Article
Proton-Coupled Folate Transporter
Folic Acid Antagonists
Buffers
HEPES
Tumor Microenvironment
5
Citations
(Scopus)
Hereditary folate malabsorption due to a mutation in the external gate of the proton-coupled folate transporter SLC46A1
Aluri, S., Zhao, R., Lubout, C., Goorden, S. M. I., Fiser, A. & Goldman, I. D., Jan 9 2018, In : Blood advances. 2, 1, p. 61-68 8 p.Research output: Contribution to journal › Article
Proton-Coupled Folate Transporter
Folic Acid
Mutation
Folic Acid Antagonists
Choroid Plexus
1
Citation
(Scopus)
Substituted-cysteine accessibility and cross-linking identify an exofacial cleft in the 7th and 8th helices of the proton-coupled folate transporter (SLC46A1)
Aluri, S., Zhao, R., Fiser, A. & Goldman, I. D., Mar 1 2018, In : American Journal of Physiology - Cell Physiology. 314, 3, p. C289-C296Research output: Contribution to journal › Article
Proton-Coupled Folate Transporter
Folic Acid
Disulfides
Pemetrexed
Cysteine