• 9549 Citations
  • 54 h-Index
1968 …2019
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Fingerprint Dive into the research topics where I. David Goldman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Folic Acid Medicine & Life Sciences
Methotrexate Medicine & Life Sciences
Reduced Folate Carrier Protein Medicine & Life Sciences
Proton-Coupled Folate Transporter Medicine & Life Sciences
Folic Acid Antagonists Medicine & Life Sciences
Ehrlich Tumor Carcinoma Medicine & Life Sciences
Pemetrexed Medicine & Life Sciences
Leukemia L1210 Medicine & Life Sciences

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Grants 1976 2019

Folic Acid Antagonists
Folic Acid
Proton-Coupled Folate Transporter
Mutation
Pemetrexed

POSTDOCTORAL TRAINING IN CANCER BIOLOGY

Goldman, I. D., Westin, E. & Grant, S.

National Institutes of Health

7/1/876/30/99

Project: Research project

Membranes
Pharmaceutical Preparations
Neoplasms
Drug Resistance
Neoplastic Processes
Folic Acid Antagonists
Pharmacology
Folic Acid
Membranes
Antineoplastic Agents

MEMBRANE PHENOMENA RELEVANT TO CARDIOVASCULAR DISEASE

Goldman, I. D., Westin, E. & Dessypris, E.

National Institutes of Health

7/1/806/30/98

Project: Research project

Publications 1968 2019

  • 9549 Citations
  • 54 h-Index
  • 207 Article
  • 17 Chapter
  • 1 Conference contribution

Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation

Aluri, S., Zhao, R., Lin, K., Shin, D. S., Fiser, A. & Goldman, I. D., Jan 1 2019, In : Journal of Biological Chemistry. 294, 18, p. 7245-7258 14 p.

Research output: Contribution to journalArticle

Proton-Coupled Folate Transporter
Conformations
Substitution reactions
Cysteine
Scaffolds

Upregulation of reduced folate carrier by Vitamin D enhances brain folate uptake in mice lacking folate receptor alpha

Alam, C., Aufreiter, S., Georgiou, C. J., Hoque, M. T., Finnell, R. H., O'Connor, D. L., Goldman, I. D. & Bendayan, R., Aug 27 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17531-17540 10 p.

Research output: Contribution to journalArticle

Open Access
Reduced Folate Carrier Protein
Folic Acid
Vitamin D
Up-Regulation
Brain
Proton-Coupled Folate Transporter
Folic Acid Antagonists
Buffers
HEPES
Tumor Microenvironment
5 Citations (Scopus)

Hereditary folate malabsorption due to a mutation in the external gate of the proton-coupled folate transporter SLC46A1

Aluri, S., Zhao, R., Lubout, C., Goorden, S. M. I., Fiser, A. & Goldman, I. D., Jan 9 2018, In : Blood advances. 2, 1, p. 61-68 8 p.

Research output: Contribution to journalArticle

Proton-Coupled Folate Transporter
Folic Acid
Mutation
Folic Acid Antagonists
Choroid Plexus
1 Citation (Scopus)
Proton-Coupled Folate Transporter
Folic Acid
Disulfides
Pemetrexed
Cysteine