• 4662 Citations
  • 18 h-Index
19952016

Research output per year

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Publications

  • 4662 Citations
  • 18 h-Index
  • 19 Article
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Article
2016

Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation

He, S., Limi, S., Estrada, R. S., Xie, Q., Brennan, L. A., Kantorow, W. L., Kokavec, J., Majumdar, R., Hou, H., Edelmann, W., Liu, W., Ashery-Padan, R., Zavadil, J., Kantorow, M., Skoultchi, A. I., Stopka, T. & Cvekl, A., Jun 1 2016, In : Development (Cambridge). 143, 11, p. 1937-1947 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
2015

Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting

Chen, H. J., Sun, J., Huang, Z., Hou, H., Arcilla, M., Rakhilin, N., Joe, D. J., Choi, J., Gadamsetty, P., Milsom, J., Nandakumar, G., Longman, R., Zhou, X. K., Edwards, R., Chen, J., Chen, K. Y., Bu, P., Wang, L., Xu, Y., Munroe, R. & 8 others, Abratte, C., Miller, A. D., Gümüş, Z. H., Shuler, M., Nishimura, N., Edelmann, W., Shen, X. & Lipkin, S. M., Jun 11 2015, In : Nature biotechnology. 33, 6, p. 656-660 5 p.

Research output: Contribution to journalArticle

20 Scopus citations
2012

Germline deletion of Igh 3′ regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus

Volpi, S. A., Verma-Gaur, J., Hassan, R., Ju, Z., Roa, S., Chatterjee, S., Werling, U., Hou, H., Will, B., Steidl, U., Scharff, M., Edelman, W., Feeney, A. J. & Birshtein, B. K., Mar 15 2012, In : Journal of Immunology. 188, 6, p. 2556-2566 11 p.

Research output: Contribution to journalArticle

28 Scopus citations
2010

An Msh2 Conditional Knockout Mouse for Studying Intestinal Cancer and Testing Anticancer Agents

Kucherlapati, M. H., Lee, K., Nguyen, A. A., Clark, A. B., Hou, H., Rosulek, A., Li, H., Yang, K., Fan, K., Lipkin, M., Bronson, R. T., Jelicks, L., Kunkel, T. A., Kucherlapati, R. & Edelmann, W., Mar 2010, In : Gastroenterology. 138, 3, p. 993-1002.e1

Research output: Contribution to journalArticle

44 Scopus citations

PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance

Van Oers, J. M. M., Roa, S., Werling, U., Liu, Y., Genschel, J., Hou, H., Sellers, R. S., Modrich, P., Scharff, M. D. & Edelmann, W., Jul 27 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 30, p. 13384-13389 6 p.

Research output: Contribution to journalArticle

40 Scopus citations
2008

Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis

Avdievich, E., Reiss, C., Scherer, S. J., Zhang, Y., Maier, S. M., Jin, B., Hou, H., Rosenwald, A., Riedmiller, H., Kucherlapati, R., Cohen, P. E., Edelmann, W. & Kneitz, B., Mar 18 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 11, p. 4247-4252 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
2003

Inactivation of exonuclease I in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility

Wei, K., Clark, A. B., Wong, E., Kane, M. F., Mazur, D. J., Parris, T., Kolas, N. K., Russell, R., Hou, H., Kneitz, B., Yang, G., Kunkel, T. A., Kolodner, R. D., Cohen, P. E. & Edelmann, W., Mar 1 2003, In : Genes and Development. 17, 5, p. 603-614 12 p.

Research output: Contribution to journalArticle

233 Scopus citations
2002

Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae

Razani, B., Wang, X. B., Engelman, J. A., Battista, M., Lagaud, G., Zhang, X. L., Kneitz, B., Hou, H., Christ, G. J., Edelmann, W. & Lisanti, M. P., Mar 25 2002, In : Molecular and cellular biology. 22, 7, p. 2329-2344 16 p.

Research output: Contribution to journalArticle

237 Scopus citations

Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex

Alland, L., David, G., Shen-Li, H., Potes, J., Muhle, R., Lee, H. C., Hou, H., Chen, K. & DePinho, R. A., Apr 10 2002, In : Molecular and cellular biology. 22, 8, p. 2743-2750 8 p.

Research output: Contribution to journalArticle

84 Scopus citations
2001

Caveolin-1 Null Mice Are Viable but Show Evidence of Hyperproliferative and Vascular Abnormalities

Razani, B., Engelman, J. A., Wang, X. B., Schubert, W., Zhang, X. L., Marks, C. B., Macalusol, F., Russell, R. G., Li, M., Pestell, R. G., Di Vizio, D., Hou, H., Kneitz, B., Lagaud, G., Christ, G. J., Edelmann, W. & Lisanti, M. P., Oct 12 2001, In : Journal of Biological Chemistry. 276, 41, p. 38121-38138 18 p.

Research output: Contribution to journalArticle

938 Scopus citations

Caveolin-3 Null Mice Show a Loss of Caveolae, Changes in the Microdomain Distribution of the Dystrophin-Glycoprotein Complex, and T-tubule Abnormalities

Galbiati, F., Engelman, J. A., Volonte, D., Zhang, X. L., Minetti, C., Li, M., Hou, H., Kneitz, B., Edelmann, W. & Lisanti, M. P., Jun 15 2001, In : Journal of Biological Chemistry. 276, 24, p. 21425-21433 9 p.

Research output: Contribution to journalArticle

332 Scopus citations
2000

Cardiac defects and renal failure in mice with targeted mutations in Pkd2

Wu, G., Markowitz, G. S., Li, L., D'Agati, V. D., Factor, S. M., Geng, L., Tibara, S., Tuchman, J., Cai, Y., Park, J. H., Van Adelsberg, J., Hou, H., Kucherlapati, R., Edelmann, W. & Somlo, S., Jan 21 2000, In : Nature Genetics. 24, 1, p. 75-78 4 p.

Research output: Contribution to journalArticle

263 Scopus citations

Essential role for Max in early embryonic growth and development

Shen-Li, H., O'Hagan, R. C., Hou, H., Horner, J. W., Lee, H. W. & DePinho, R. A., Jan 1 2000, In : Genes and Development. 14, 1, p. 17-22 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice

Kneitz, B., Cohen, P. E., Avdievich, E., Zhu, L., Kane, M. F., Hou, H., Kolodner, R. D., Kucherlapati, R., Pollard, J. W. & Edelmann, W., May 1 2000, In : Genes and Development. 14, 9, p. 1085-1097 13 p.

Research output: Contribution to journalArticle

320 Scopus citations
1998

Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth

Schreiber-Agus, N., Meng, Y., Hoang, T., Hou, H., Ghen, K., Greenberg, R., Cordon-Cardo, C., Leet, H. W. & Depinho, R. A., Jun 4 1998, In : Nature. 393, 6684, p. 483-487 5 p.

Research output: Contribution to journalArticle

162 Scopus citations

Somatic inactivation of Pkd2 results in polycystic kidney disease

Wu, G., D'Agati, V., Cai, Y., Markowitz, G., Park, J. H., Reynolds, D. M., Maeda, Y., Le, T. C., Hou, H., Kucherlapati, R., Edelmann, W. & Somlo, S., Apr 17 1998, In : Cell. 93, 2, p. 177-188 12 p.

Research output: Contribution to journalArticle

416 Scopus citations
1997

Altered cell differentiation and proliferation in mice lacking p57(KIP2) indicates a role in Beckwith-Wiedemann syndrome

Zhang, P., Liégeois, N. J., Wong, C., Finegold, M., Hou, H., Thompson, J. C., Silverman, A., Harper, J. W., DePinho, R. A. & Elledge, S. J., May 8 1997, In : Nature. 387, 6629, p. 151-158 8 p.

Research output: Contribution to journalArticle

608 Scopus citations

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

Alland, L., Muhle, R., Hou, H., Potes, J., Chin, L., Schreiber-Agus, N. & DePinho, R. A., May 1 1997, In : Nature. 387, 6628, p. 49-55 7 p.

Research output: Contribution to journalArticle

711 Scopus citations
1995

Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene

Bali, D., Svetlanov, A., Lee, H. W., Fusco-DeMane, D., Leiser, M., Li, B., Barzilai, N., Surana, M., Hou, H., Fleischer, N., DePinho, R., Rossetti, L. & Efrat, S., Jan 1 1995, In : Journal of Biological Chemistry. 270, 37, p. 21464-21467 4 p.

Research output: Contribution to journalArticle

121 Scopus citations