• 5883 Citations
  • 34 h-Index
1986 …2020

Research output per year

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Publications

2019

CCL2 mobilizes ALIX to facilitate Gag-p6 mediated HIV-1 virion release

Ajasin, D. O., Rao, V. R., Wu, X., Ramasamy, S., Pujato, M., Ruiz, A. P., Fiser, A., Bresnick, A. R., Kalpana, G. V. & Prasad, V. R., Jun 2019, In : eLife. 8, e35546.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2017

FISHing out the hidden enemy: Advances in detecting and measuring latent HIV-infected cells

Prasad, V. R. & Kalpana, G. V., Sep 1 2017, In : mBio. 8, 5, e01433-17.

Research output: Contribution to journalComment/debate

4 Scopus citations
2016

An essential role of INI1/hSNF5 chromatin remodeling protein in HIV-1 posttranscriptional events and Gag/Gag-Pol stability

Porte, A. L., Cano, J., Wu, X., Mitra, D. & Kalpana, G. V., 2016, In : Journal of virology. 90, 21, p. 9889-9904 16 p.

Research output: Contribution to journalArticle

Computational modeling of Repeat1 region of INI1/hSNF5: An evolutionary link with ubiquitin

Bhutoria, S., Kalpana, G. V. & Acharya, S. A., Sep 1 2016, In : Protein Science. p. 1593-1604 12 p.

Research output: Contribution to journalArticle

Quantification of HIV-1 gag localization within virus producer cells

Porte, A. L. & Kalpana, G. V., 2016, Methods in Molecular Biology. Humana Press Inc., Vol. 1354. p. 165-174 10 p. (Methods in Molecular Biology; vol. 1354).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2014

Dopamine receptor activation increases HIV entry into primary human macrophages

Gaskill, P. J., Yano, H. H., Kalpana, G. V., Javitch, J. A. & Berman, J. W., Sep 30 2014, In : PloS one. 9, 9, e108232.

Research output: Contribution to journalArticle

32 Scopus citations
2013

INI1/hSNF5-interaction defective HIV-1 IN mutants exhibit impaired particle morphology, reverse transcription and integration in vivo

Mathew, S., Nguyen, M., Wu, X., Pal, A., Shah, V. B., Prasad, V. R., Aiken, C. & Kalpana, G. V., Jun 24 2013, In : Retrovirology. 10, 1, 66.

Research output: Contribution to journalArticle

8 Scopus citations

Novel yeast-based strategy unveils antagonist binding regions on the nuclear xenobiotic receptor PXR

Li, H., Redinbo, M. R., Venkatesh, M., Ekins, S., Chaudhry, A., Bloch, N., Negassa, A., Mukherjee, P., Kalpana, G. & Mani, S., May 10 2013, In : Journal of Biological Chemistry. 288, 19, p. 13655-13668 14 p.

Research output: Contribution to journalArticle

25 Scopus citations

Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria

Plotkin, S. R., Blakeley, J. O., Evans, D. G., Hanemann, C. O., Hulsebos, T. J. M., Hunter-Schaedle, K., Kalpana, G. V., Korf, B., Messiaen, L., Papi, L., Ratner, N., Sherman, L. S., Smith, M. J., Stemmer-Rachamimov, A. O., Vitte, J. & Giovannini, M., Mar 2013, In : American Journal of Medical Genetics, Part A. 161, 3, p. 405-416 12 p.

Research output: Contribution to journalArticle

95 Scopus citations
2011

Aurora A is a repressed effector target of the chromatin remodeling protein INI1/hSNF5 required for rhabdoid tumor cell survival

Lee, S. J., Cimica, V., Ramachandra, N., Zagzag, D. & Kalpana, G. V., May 1 2011, In : Cancer Research. 71, 9, p. 3225-3235 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Inhibition of early stages of HIV-1 assembly by INI1/hSNF5 transdominant negative mutant S6

Cano, J. & Kalpana, G. V., Mar 2011, In : Journal of virology. 85, 5, p. 2254-2265 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

In vitro activities of novel 4-HPR derivatives on a panel of rhabdoid and other tumor cell lines

Smith, M. E., Das, B. C. & Kalpana, G. V., Sep 27 2011, In : Cancer Cell International. 11, 34.

Research output: Contribution to journalArticle

7 Scopus citations

Therapeutically targeting cyclin D1 in primary tumors arising from loss of Ini1

Smith, M. E., Cimica, V., Chinni, S., Jana, S., Koba, W., Yang, Z., Fine, E., Zagzag, D., Montagna, C. & Kalpana, G. V., Jan 4 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 1, p. 319-324 6 p.

Research output: Contribution to journalArticle

28 Scopus citations
2010

Development of targeted therapies for rhabdoid tumors based on the functions of INI1/hSNF5 tumor suppressor

Kalpana, G. V. & Smith, M. E., Dec 1 2010, Molecularly Targeted Therapy for Childhood Cancer. Springer New York, p. 305-330 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Potent inhibition of rhabdoid tumor cells by combination of flavopiridol and 4OH-tamoxifen

Cimica, V., Smith, M. E., Zhang, Z., Mathur, D., Mani, S. & Kalpana, G. V., Nov 19 2010, In : BMC Cancer. 10, 634.

Research output: Contribution to journalArticle

13 Scopus citations
2009

Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2

Evans, D. G., Kalamarides, M., Hunter-Schaedle, K., Blakeley, J., Allen, J., Babovic-Vuskanovic, D., Belzberg, A., Bollag, G., Chen, R., DiTomaso, E., Golfinos, J., Harris, G., Jacob, A., Kalpana, G., Karajannis, M., Korf, B., Kurzrock, R., Law, M., McClatchey, A., Packer, R. & 8 others, Roehm, P., Rubenstein, A., Slattery, W., Tonsgard, J. H., Welling, D. B., Widemann, B., Yohay, K. & Giovannini, M., Aug 15 2009, In : Clinical Cancer Research. 15, 16, p. 5032-5039 8 p.

Research output: Contribution to journalReview article

53 Scopus citations

HIV Protocols: Preface

Prasad, V. R. & Kalpana, G. V., Feb 23 2009, HIV Protocols. Prasad, V. R. & Kalpana, G. V. (eds.). p. v-vi (Methods in Molecular Biology; vol. 485).

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Multimerization and DNA binding properties of INI1/hSNF5 and its functional significance

Das, S., Cano, J. & Kalpana, G. V., Jul 24 2009, In : Journal of Biological Chemistry. 284, 30, p. 19903-19914 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Recruitment of a SAP18-HDAC1 complex into HIV-1 virions and its requirement for viral replication

Sorin, M., Cano, J., Das, S., Mathew, S., Wu, X., Davies, K. P., Shi, X., Cheng, S. W. G., Ott, D. & Kalpana, G. V., Jun 2009, In : PLoS pathogens. 5, 6, e1000463.

Research output: Contribution to journalArticle

41 Scopus citations

Reverse two-hybrid screening to analyze protein-protein interaction of HIV-1 viral and cellular proteins

Das, S. & Kalpana, G. V., 2009, HIV Protocols. Prasad, V. R. & Kalpana, G. V. (eds.). p. 271-293 23 p. (Methods in Molecular Biology; vol. 485).

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Scopus citations
2008

Contribution of the C-terminal region within the catalytic core domain of HIV-1 integrase to yeast lethality, chromatin binding and viral replication

Xu, Z., Zheng, Y., Ao, Z., Clement, M., Mouland, A. J., Kalpana, G. V., Belhumeur, P., Cohen, É. A. & Yao, X. J., 2008, In : Retrovirology. 5, 102.

Research output: Contribution to journalArticle

6 Scopus citations

Design, synthesis of novel peptidomimetic derivatives of 4-HPR for rhabdoid tumors

Das, B. C., Smith, M. E. & Kalpana, G. V., Jul 15 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 14, p. 4177-4180 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Design and synthesis of 4-HPR derivatives for rhabdoid tumors

Das, B. C., Smith, M. E. & Kalpana, G. V., Jul 1 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 13, p. 3805-3808 4 p.

Research output: Contribution to journalArticle

16 Scopus citations

Rhabdoid tumor growth is inhibited by flavopiridol

Smith, M. E., Cimica, V., Chinni, S., Challagulla, K., Mani, S. & Kalpana, G. V., Jan 15 2008, In : Clinical Cancer Research. 14, 2, p. 523-532 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor

Wang, H., Li, H., Moore, L. B., Johnson, M. D. L., Maglich, J. M., Goodwin, B., Ittoop, O. R. R., Wisely, B., Creech, K., Parks, D. J., Collins, J. L., Willson, T. M., Kalpana, G. V., Venkatesh, M., Xie, W., Cho, S. Y., Roboz, J., Redinbo, M., Moore, J. T. & Mani, S., Apr 2008, In : Molecular Endocrinology. 22, 4, p. 838-857 20 p.

Research output: Contribution to journalArticle

90 Scopus citations
2007

Activated pregnenolone X-receptor is a target for ketoconazole and its analogs

Wang, H., Huang, H., Li, H., Teotico, D. G., Sinz, M., Baker, S. D., Staudinger, J., Kalpana, G., Redinbo, M. R. & Mani, S., Apr 15 2007, In : Clinical Cancer Research. 13, 8, p. 2488-2495 8 p.

Research output: Contribution to journalArticle

83 Scopus citations

Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole

Huang, H., Wang, H., Sinz, M., Zoeckler, M., Staudinger, J., Redinbo, M. R., Teotico, D. G., Locker, J., Kalpana, G. V. & Mani, S., Jan 11 2007, In : Oncogene. 26, 2, p. 258-268 11 p.

Research output: Contribution to journalArticle

157 Scopus citations

INI1 induces interferon signaling and spindle checkpoint in rhabdoid tumors

Morozov, A., Seung, J. L., Zhang, Z. K., Cimica, V., Zagzag, D. & Kalpana, G. V., Aug 15 2007, In : Clinical Cancer Research. 13, 16, p. 4721-4730 10 p.

Research output: Contribution to journalArticle

29 Scopus citations
2006

Dynamics of virus-host interplay in HIV-1 replication

Sorin, M. & Kalpana, G. V., Apr 2006, In : Current HIV Research. 4, 2, p. 117-130 14 p.

Research output: Contribution to journalReview article

27 Scopus citations

HIV-1 replication in cell lines harboring INI1/hSNF5 mutations

Sorin, M., Yung, E., Wu, X. & Kalpana, G. V., Aug 31 2006, In : Retrovirology. 3, 56.

Research output: Contribution to journalArticle

26 Scopus citations

Targeting cyclin D1, a downstream effector of INI1/hSNF5, in rhabdoid tumors

Alarcon-Vargas, D., Zhang, Z., Agarwal, B., Challagulla, K., Mani, S. & Kalpana, G. V., Feb 2 2006, In : Oncogene. 25, 5, p. 722-734 13 p.

Research output: Contribution to journalArticle

56 Scopus citations
2005

Activation of the steroid and xenobiotic receptor (human pregnane X receptor) by nontaxane microtubule-stabilizing agents

Mani, S., Huang, H., Sundarababu, S., Liu, W., Kalpana, G., Smith, A. B. & Horwitz, S. B., Sep 1 2005, In : Clinical Cancer Research. 11, 17, p. 6359-6369 11 p.

Research output: Contribution to journalArticle

61 Scopus citations

Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss

Tsikitis, M., Zhang, Z., Edelman, W., Zagzag, D. & Kalpana, G. V., Aug 23 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 34, p. 12129-12134 6 p.

Research output: Contribution to journalArticle

89 Scopus citations
2004

Interaction between Human Immunodeficiency Virus Type 1 Reverse Transcriptase and Integrase Proteins

Hehl, E. A., Joshi, P., Kalpana, G. V. & Prasad, V. R., May 2004, In : Journal of virology. 78, 10, p. 5056-5067 12 p.

Research output: Contribution to journalArticle

88 Scopus citations

Specificity of Interaction of INI1/hSNF5 with Retroviral Integrases and Its Functional Significance

Yung, E., Sorin, M., Wang, E. J., Perumal, S., Ott, D. & Kalpana, G. V., Mar 1 2004, In : Journal of virology. 78, 5, p. 2222-2231 10 p.

Research output: Contribution to journalArticle

57 Scopus citations
2002

A masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export: Implications for tumorigenesis

Craig, E., Zhang, Z. K., Davies, K. P. & Kalpana, G. V., Jan 15 2002, In : EMBO Journal. 21, 1-2, p. 31-42 12 p.

Research output: Contribution to journalArticle

76 Scopus citations

Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5

Zhang, Z. K., Davies, K. P., Allen, J., Zhu, L., Pestell, R. G., Zagzag, D. & Kalpana, G. V., 2002, In : Molecular and cellular biology. 22, 16, p. 5975-5988 14 p.

Research output: Contribution to journalArticle

192 Scopus citations

The role of INI1 and the SWI/SNF complex in the development of rhabdoid tumors: Meeting summary from the workshop on childhood atypical teratoid/rhabdoid tumors

Biegel, J. A., Kalpana, G., Knudsen, E. S., Packer, R. J., Roberts, C. W. M., Thiele, C. J., Smith, M. & Weissman, B., Jan 1 2002, In : Cancer Research. 62, 1, p. 323-328 6 p.

Research output: Contribution to journalArticle

156 Scopus citations
2001

Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: Interference with early steps of viral replication

Turelli, P., Doucas, V., Craig, E., Mangeat, B., Klages, N., Evans, R., Kalpana, G. & Trono, D., Jan 1 2001, In : Molecular Cell. 7, 6, p. 1245-1254 10 p.

Research output: Contribution to journalArticle

192 Scopus citations

Homodimerization of Human Bilirubin-Uridine-diphosphoglucuronate Glucuronosyltransferase-1 (UGT1A1) and Its Functional Implications

Ghosh, S. S., Sappal, B. S., Kalpana, G. V., Leet, S. W., Roy Chowdhury, J. & Roy Chowdhury, N., Nov 9 2001, In : Journal of Biological Chemistry. 276, 45, p. 42108-42115 8 p.

Research output: Contribution to journalArticle

80 Scopus citations

Inhibition of HIV-1 virion production by a transdominant mutant of integrase interactor 1

Yung, E., Sorin, M., Pal, A., Craig, E., Morozov, A., Delattre, O., Kappes, J., Ott, D. & Kalpana, G. V., Aug 29 2001, In : Nature Medicine. 7, 8, p. 920-926 7 p.

Research output: Contribution to journalArticle

117 Scopus citations
1999

c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function

Cheng, S. W. G., Davies, K. P., Yung, E., Beltran, R. J., Yu, J. & Kalpana, G. V., May 1 1999, In : Nature Genetics. 22, 1, p. 102-105 4 p.

Research output: Contribution to journalArticle

292 Scopus citations

Human immunodeficiency virus type 1 integrase protein promotes reverse transcription through specific interactions with the nucleoprotein reverse transcription complex

Wu, X., Liu, H., Xiao, H., Conway, J. A., Hehl, E., Kalpana, G. V., Prasad, V. & Kappes, J. C., 1999, In : Journal of virology. 73, 3, p. 2126-2135 10 p.

Research output: Contribution to journalArticle

Open Access
166 Scopus citations

Interaction of E1 and hSNF5 proteins stimulates replication of human papillomavirus DNA

Lee, D., Sohn, H., Kalpana, G. V. & Choe, J., Jun 3 1999, In : Nature. 399, 6735, p. 487-491 5 p.

Research output: Contribution to journalArticle

96 Scopus citations

Isolation and characterization of an oligomerization-negative mutant of HIV-1 integrase

Kalpana, G. V., Reicin, A., Cheng, G. S. W., Sorin, M., Paik, S. & Goff, S. P., Jul 5 1999, In : Virology. 259, 2, p. 274-285 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Retroviral vectors for liver-directed gene therapy

Kalpana, G. V., 1999, In : Seminars in liver disease. 19, 1, p. 27-37 11 p.

Research output: Contribution to journalReview article

33 Scopus citations
1998
79 Scopus citations
1996

Auxotrophic vaccines for tuberculosis

Guleria, I., Teitelbaum, R., McAdam, R. A., Kalpana, G., Jacobs, W. R. & Bloom, B. R., 1996, In : Nature Medicine. 2, 3, p. 334-337 4 p.

Research output: Contribution to journalArticle

146 Scopus citations

Epstein-Barr virus nuclear protein 2 (EBNA2) binds to a component of the human SNF-SWI complex, hSNF5/Ini1

Wu, D. Y., Kalpana, G. V., Goff, S. P. & Schubach, W. H., Sep 1996, In : Journal of virology. 70, 9, p. 6020-6028 9 p.

Research output: Contribution to journalArticle

Open Access
113 Scopus citations

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex

Wang, W., Côté, J., Xue, Y., Zhou, S., Khavari, P. A., Biggar, S. R., Muchardt, C., Kalpana, G. V., Goff, S. P., Yaniv, M., Workman, J. L. & Crabtree, G. R., Oct 1 1996, In : EMBO Journal. 15, 19, p. 5370-5382 13 p.

Research output: Contribution to journalArticle

615 Scopus citations