• 4632 Citations
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1993 …2024

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2020

Circulating microRNAs as Biomarkers of Radiation Exposure: A Systematic Review and Meta-Analysis

Małachowska, B., Tomasik, B., Stawiski, K., Kulkarni, S., Guha, C., Chowdhury, D. & Fendler, W., Feb 1 2020, In : International Journal of Radiation Oncology Biology Physics. 106, 2, p. 390-402 13 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Evaluating dosimetric constraints for carbon ion radiotherapy in the treatment of locally advanced pancreatic cancer

Lin, L. C., Jiang, G. L., Ohri, N., Wang, Z., Lu, J. J., Garg, M., Guha, C. & Wu, X., May 7 2020, In : Radiation Oncology. 15, 1, 101.

Research output: Contribution to journalArticle

Open Access

Lymphocyte-Sparing Radiotherapy: The Rationale for Protecting Lymphocyte-rich Organs When Combining Radiotherapy With Immunotherapy

Lambin, P., Lieverse, R. I. Y., Eckert, F., Marcus, D., Oberije, C., van der Wiel, A. M. A., Guha, C., Dubois, L. J. & Deasy, J. O., Apr 2020, In : Seminars in Radiation Oncology. 30, 2, p. 187-193 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Novel calreticulin-nanoparticle in combination with focused ultrasound induces immunogenic cell death in melanoma to enhance antitumor immunity

Sethuraman, S. N., Singh, M. P., Patil, G., Li, S., Fiering, S., Hoopes, P. J., Guha, C., Malayer, J. & Ranjan, A., Jan 1 2020, In : Theranostics. 10, 8, p. 3397-3412 16 p.

Research output: Contribution to journalArticle

Open Access

Postablation modulation after single high-dose radiation therapy improves tumor control via enhanced immunomodulation

Savage, T., Pandey, S. & Guha, C., Feb 15 2020, In : Clinical Cancer Research. 26, 4, p. 910-921 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Trials and Tribulations of Radio-Immuno-Oncology

Guha, C., Apr 2020, In : Seminars in Radiation Oncology. 30, 2, p. 108-112 5 p.

Research output: Contribution to journalArticle

2019
4 Scopus citations
1 Scopus citations

BHLHA15-Positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice

Hayakawa, Y., Tsuboi, M., Asfaha, S., Kinoshita, H., Niikura, R., Konishi, M., Hata, M., Oya, Y., Kim, W., Middelhoff, M., Hikiba, Y., Higashijima, N., Ihara, S., Ushiku, T., Fukayama, M., Tailor, Y., Hirata, Y., Guha, C., Yan, K. S., Koike, K. & 1 others, Wang, T. C., Mar 2019, In : Gastroenterology. 156, 4, p. 1066-1081.e16

Research output: Contribution to journalArticle

5 Scopus citations
1 Scopus citations
Open Access
1 Scopus citations
1 Scopus citations
1 Scopus citations

Immunomodulatory Effects of Stereotactic Body Radiation Therapy: Preclinical Insights and Clinical Opportunities

Marciscano, A. E., Haimovitz-Friedman, A., Lee, P., Tran, P. T., Tomé, W. A., Guha, C., (Spring) Kong, F. M., Sahgal, A., El Naqa, I., Rimner, A., Marks, L. B., Formenti, S. C. & DeWeese, T. L., Jan 1 2019, In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

6 Scopus citations

In-situ vaccination using focused ultrasound heating and anti-CD-40 agonistic antibody enhances T-cell mediated local and abscopal effects in murine melanoma

Singh, M. P., Sethuraman, S. N., Ritchey, J., Fiering, S., Guha, C., Malayer, J. & Ranjan, A., Nov 29 2019, In : International Journal of Hyperthermia. 36, sup1, p. 64-73 10 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Low Intensity Focused Ultrasound (LOFU)-mediated Acoustic Immune Priming and Ablative Radiation Therapy for in situ Tumor Vaccines

Skalina, K. A., Singh, S., Chavez, C. G., Macian, F. & Guha, C., Dec 1 2019, In : Scientific reports. 9, 1, 15516.

Research output: Contribution to journalArticle

Open Access

Nestin+NG2+ Cells Form a Reserve Stem Cell Population in the Mouse Prostate

Hanoun, M., Arnal-Estapé, A., Maryanovich, M., Zahalka, A. H., Bergren, S. K., Chua, C. W., Leftin, A., Brodin, P. N., Shen, M. M., Guha, C. & Frenette, P. S., Jun 11 2019, In : Stem Cell Reports. 12, 6, p. 1201-1211 11 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Optimal targeting of BCL-family proteins in head and neck squamous cell carcinoma requires inhibition of both BCL-xL and MCL-1

Ow, T. J., Fulcher, C. D., Thomas, C., Broin, P., López, A., Reyna, D. E., Smith, R. V., Sarta, C., Prystowsky, M. B., Schlecht, N. F., Schiff, B. A., Rosenblatt, G., Belbin, T. J., Harris, T. M., Childs, G. J., Kawachi, N., Guha, C. & Gavathiotis, E., Jan 1 2019, In : Oncotarget. 10, 4, p. 494-510 17 p.

Research output: Contribution to journalArticle

6 Scopus citations

Radiation-primed hepatocyte transplantation in murine monogeneic dyslipidemia normalizes cholesterol and prevents atherosclerosis

Barahman, M., Zhang, W., Harris, H. Y., Aiyer, A., Kabarriti, R., Kinkhabwala, M., Roy-Chowdhury, N., Beck, A. P., Scanlan, T. S., Roy-Chowdhury, J., Asp, P. & Guha, C., Jun 2019, In : Journal of Hepatology. 70, 6, p. 1170-1179 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Radiation therapy for patients with newly diagnosed metastatic head and neck squamous cell carcinoma

Kabarriti, R., Baliga, S., Ohri, N., Guha, C., Kalnicki, S. & Garg, M. K., Jan 2019, In : Head and Neck. 41, 1, p. 130-138 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Therapeutic potential of adenovirus-mediated TFF2-CTP-Flag peptide for treatment of colorectal cancer

Dubeykovskaya, Z. A., Duddempudi, P. K., Deng, H., Valenti, G., Cuti, K. L., Nagar, K., Tailor, Y., Guha, C., Kitajewski, J. & Wang, T. C., Feb 1 2019, In : Cancer gene therapy. 26, 1-2, p. 48-57 10 p.

Research output: Contribution to journalArticle

2018

Expression of the DNA repair gene MLH1 correlates with survival in patients who have resected pancreatic cancer and have received adjuvant chemoradiation: NRG Oncology RTOG Study 9704

Lawrence, Y. R., Moughan, J., Magliocco, A. M., Klimowicz, A. C., Regine, W. F., Mowat, R. B., DiPetrillo, T. A., Small, W., Simko, J. P., Golan, T., Winter, K. A., Guha, C., Crane, C. H. & Dicker, A. P., Feb 1 2018, In : Cancer. 124, 3, p. 491-498 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2 Scopus citations
2017
5 Scopus citations
8 Scopus citations

Evolutionarily conserved serum microRNAs predict radiation-induced fatality in nonhuman primates

Fendler, W., Malachowska, B., Meghani, K., Konstantinopoulos, P. A., Guha, C., Singh, V. K. & Chowdhury, D., Mar 1 2017, In : Science Translational Medicine. 9, 379, eaal2408.

Research output: Contribution to journalArticle

18 Scopus citations

Host conditioning and rejection monitoring in hepatocyte transplantation in humans

Soltys, K. A., Setoyama, K., Tafaleng, E. N., Soto Gutiérrez, A., Fong, J., Fukumitsu, K., Nishikawa, T., Nagaya, M., Sada, R., Haberman, K., Gramignoli, R., Dorko, K., Tahan, V., Dreyzin, A., Baskin, K., Crowley, J. J., Quader, M. A., Deutsch, M., Ashokkumar, C., Shneider, B. L. & 15 others, Squires, R. H., Ranganathan, S., Reyes-Mugica, M., Dobrowolski, S. F., Mazariegos, G., Elango, R., Stolz, D. B., Strom, S. C., Vockley, G., Roy-Chowdhury, J., Cascalho, M., Guha, C., Sindhi, R., Platt, J. L. & Fox, I. J., May 2017, In : Journal of Hepatology. 66, 5, p. 987-1000 14 p.

Research output: Contribution to journalArticle

32 Scopus citations

Preclinical evaluation of radiation and systemic, RGD-Targeted, adeno-Associated virus phage-TNF gene therapy in a mouse model of spontaneously metastatic melanoma

Quinn, T. J., Healy, N., Sara, A., Maggi, E., Claros, C. S., Kabarriti, R., Scandiuzzi, L., Liu, L., Gorecka, J., Adem, A., Basu, I., Yuan, Z. & Guha, C., Jan 1 2017, In : Cancer Gene Therapy. 24, 1, p. 13-19 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

SBRT for recurrent head and neck cancer

Garg, M. K., Kabarriti, R., Baliga, S., Guha, C., Tome, W. A. & Kalnicki, S., Feb 3 2017, In : Journal of Physics: Conference Series. 777, 1, 012025.

Research output: Contribution to journalArticle

Significance of Co-expression of Epidermal Growth Factor Receptor and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiotherapy: An Analysis of NRG Oncology RTOG 9811

Doll, C. M., Moughan, J., Klimowicz, A., Ho, C. K., Kornaga, E. N., Lees-Miller, S. P., Ajani, J. A., Crane, C. H., Kachnic, L. A., Okawara, G. S., Berk, L. B., Roof, K. S., Becker, M. J., Grisell, D. L., Ellis, R. J., Sperduto, P. W., Marsa, G. W., Guha, C. & Magliocco, A. M., Mar 1 2017, In : International Journal of Radiation Oncology Biology Physics. 97, 3, p. 554-562 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Structure-guided development of a high-affinity human Programmed Cell Death-1: Implications for tumor immunotherapy

Lázár-Molnár, E., Scandiuzzi, L., Basu, I., Quinn, T., Sylvestre, E., Palmieri, E., Ramagopal, U. A., Nathenson, S. G., Guha, C. & Almo, S. C., Mar 1 2017, In : EBioMedicine. 17, p. 30-44 15 p.

Research output: Contribution to journalArticle

19 Scopus citations
2016
5 Scopus citations

A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling

Athuluri-Divakar, S. K., Vasquez-Del Carpio, R., Dutta, K., Baker, S. J., Cosenza, S. C., Basu, I., Gupta, Y. K., Reddy, M. V. R., Ueno, L., Hart, J. R., Vogt, P. K., Mulholland, D., Guha, C., Aggarwal, A. K. & Reddy, E. P., Apr 21 2016, In : Cell. 165, 3, p. 643-655 13 p.

Research output: Contribution to journalArticle

124 Scopus citations
2 Scopus citations
3 Scopus citations

Hepatocyte-like cells derived from induced pluripotent stem cells

Roy-Chowdhury, N., Wang, X., Guha, C. & Roy-Chowdhury, J., Aug 17 2016, (Accepted/In press) In : Hepatology International. p. 1-16 16 p.

Research output: Contribution to journalArticle

20 Scopus citations

Human urinary epithelial cells as a source of engraftable hepatocyte-like cells using stem cell technology

Sauer, V., Tchaikovskaya, T., Wang, X., Li, Y., Zhang, W., Tar, K., Polgar, Z., Ding, J., Guha, C., Fox, I. J., Roy-Chowdhury, N. & Roy-Chowdhury, J., Jan 1 2016, In : Cell Transplantation. 25, 12, p. 2221-2243 23 p.

Research output: Contribution to journalArticle

9 Scopus citations

Identifying Urinary and Serum Exosome Biomarkers for Radiation Exposure Using a Data Dependent Acquisition and SWATH-MS Combined Workflow

Kulkarni, S., Koller, A., Mani, K. M., Wen, R., Alfieri, A., Saha, S., Wang, J., Patel, P., Bandeira, N., Guha, C. & Chen, E. I., Nov 1 2016, In : International Journal of Radiation Oncology Biology Physics. 96, 3, p. 566-577 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

In Vitro Photoirradiation System for Simultaneous Irradiation with Different Light Doses at a Fixed Temperature

Quintanar, L. F. H., Silva, F. Y. L., Bustos, D. A. F., Navarro, J. S., De La Rosa Vázquez, J. M., Brodin, N. P., Guha, C., Tome, W. A. & Isakina, S. S., Mar 1 2016, In : Photomedicine and Laser Surgery. 34, 3, p. 108-115 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Low-intensity focused ultrasound induces reversal of tumor-induced T cell tolerance and prevents immune escape

Bandyopadhyay, S., Quinn, T. J., Scandiuzzi, L., Basu, I., Partanen, A., Tome, W. A., Macian-Juan, F. & Guha, C., Feb 15 2016, In : Journal of Immunology. 196, 4, p. 1964-1976 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury

Saha, S., Aranda, E., Hayakawa, Y., Bhanja, P., Atay, S., Brodin, N. P., Li, J., Asfaha, S., Liu, L., Tailor, Y., Zhang, J., Godwin, A. K., Tome, W. A., Wang, T. C., Guha, C. & Pollard, J. W., Oct 13 2016, In : Nature communications. 7, 13096.

Research output: Contribution to journalArticle

64 Scopus citations

Management algorithm for HIV-associated parotid lymphoepithelial cysts

Mourad, W. F., Patel, S., Young, R., Khorsandi, A. S., Concert, C., Shourbaji, R. A., Ciarrocca, K., Bakst, R. L., Shasha, D., Guha, C., Garg, M. K., Hu, K. S., Kalnicki, S. & Harrison, L. B., Feb 16 2016, (Accepted/In press) In : European Archives of Oto-Rhino-Laryngology. p. 1-8 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Pexmetinib: A novel dual inhibitor of Tie2 and p38 MAPK with efficacy in preclinical models of myelodysplastic syndromes and acute myeloid leukemia

Bachegowda, L., Morrone, K., Winski, S. L., Mantzaris, I., Bartenstein, M., Ramachandra, N., Giricz, O., Sukrithan, V., Nwankwo, G., Shahnaz, S., Bhagat, T. D., Bhattacharyya, S., Assal, A., Shastri, A., Gordon-Mitchell, S., Pellagatti, A., Boultwood, J., Schinke, C., Yu, Y., Guha, C. & 16 others, Rizzi, J., Garrus, J., Brown, S., Wollenberg, L., Hogeland, G., Wright, D., Munson, M., Rodriguez, M., Gross, S., Chantry, D., Zou, Y., Platanias, L. C., Burgess, L. E., Pradhan, K., Steidl, U. & Verma, A., Aug 15 2016, In : Cancer Research. 76, 16, p. 4841-4849 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Precision Medicine and Pancreatic Cancer

Farrell, J. J., Moughan, J., Wong, J. L., Regine, W. F., Schaefer, P., Benson, A. B., Macdonald, J. S., Liu, X., Yen, Y., Lai, R., Zheng, Z., Bepler, G., Guha, C. & Elsaleh, H., Nov 1 2016, In : Pancreas. 45, 10, p. 1485-1493 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Tumor Cells Surviving Exposure to Proton or Photon Radiation Share a Common Immunogenic Modulation Signature, Rendering Them More Sensitive to T Cell-Mediated Killing

Gameiro, S. R., Malamas, A. S., Bernstein, M. B., Tsang, K. Y., Vassantachart, A., Sahoo, N., Tailor, R., Pidikiti, R., Guha, C., Hahn, S. M., Krishnan, S. & Hodge, J. W., May 1 2016, In : International Journal of Radiation Oncology Biology Physics. 95, 1, p. 120-130 11 p.

Research output: Contribution to journalArticle

43 Scopus citations
2015

Amelioration of Hyperbilirubinemia in Gunn Rats after Transplantation of Human Induced Pluripotent Stem Cell-Derived Hepatocytes

Chen, Y., Li, Y., Wang, X., Zhang, W., Sauer, V., Chang, C. J., Han, B., Tchaikovskaya, T., Avsar, Y., Tafaleng, E., Madhusudana Girija, S., Tar, K., Polgar, Z., Strom, S., Bouhassira, E. E., Guha, C., Fox, I. J., Roy-Chowdhury, J. & Roy-Chowdhury, N., Jul 14 2015, In : Stem Cell Reports. 5, 1, p. 22-30 9 p.

Research output: Contribution to journalArticle

39 Scopus citations
10 Scopus citations

Are we ready for a radiological terrorist attack yet? Report from the centers for medical countermeasures against radiation network

Brenner, D. J., Chao, N. J., Greenberger, J. S., Guha, C., McBride, W. H., Swartz, H. M. & Williams, J. P., Jul 1 2015, In : International Journal of Radiation Oncology Biology Physics. 92, 3, p. 504-505 2 p.

Research output: Contribution to journalArticle

14 Scopus citations