• 900 Citations
  • 19 h-Index
20012019
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Fingerprint Dive into the research topics where Boris A. Bartholdy is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 27 Similar Profiles
Acute Myeloid Leukemia Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
B-Lymphocytes Medicine & Life Sciences
Stem cells Chemical Compounds
Leukemia Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Cells Chemical Compounds
Myelodysplastic Syndromes Medicine & Life Sciences

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Publications 2001 2019

  • 900 Citations
  • 19 h-Index
  • 31 Article
1 Citation (Scopus)

PAK kinase inhibition has therapeutic activity in novel preclinical models of adult T-Cell leukemia/lymphoma

Chung, E. Y. L., Mai, Y., Shah, U. A., Wei, Y., Ishida, E., Kataoka, K., Ren, X., Pradhan, K., Bartholdy, B. A., Wei, X., Zou, Y., Zhang, J., Ogawa, S., Steidl, U. G., Zang, X., Verma, A. K., Janakiram, M. & Ye, B. H., Jun 15 2019, In : Clinical Cancer Research. 25, 12, p. 3589-3601 13 p.

Research output: Contribution to journalArticle

p21-Activated Kinases
Adult T Cell Leukemia Lymphoma
Therapeutics
Cell Survival
Protein Isoforms

PI3K alpha and delta promote hematopoietic stem cell activation

Hemmati, S., Sinclair, T., Tong, M., Bartholdy, B. A., Okabe, R. O., Ames, K., Ostrodka, L., Haque, T., Kaur, I., Mills, T. S., Agarwal, A., Pietras, E. M., Zhao, J. J., Roberts, T. M. & Gritsman, K., Jul 11 2019, In : JCI Insight. 4, 13, e125832.

Research output: Contribution to journalArticle

Open Access
Hematopoietic Stem Cells
Phosphatidylinositol 3-Kinases
Combination Drug Therapy
Interleukin-1
Fluorouracil

Proteome-wide analysis of chaperone-mediated autophagy targeting motifs

Kirchner, P., Bourdenx, M., Madrigal-Matute, J., Tiano, S., Diaz, A., Bartholdy, B. A., Will, B. & Cuervo, A. M., May 1 2019, In : PLoS biology. 17, 5, p. e3000301

Research output: Contribution to journalArticle

Open Access
autophagy
Autophagy
Proteome
proteome
Amino Acid Motifs
1 Citation (Scopus)

Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells

Wang, K., Guzman, A. K., Yan, Z., Zhang, S., Hu, M. Y., Hamaneh, M. B., Yu, Y. K., Tolu, S., Zhang, J., Kanavy, H. E., Ye, K., Bartholdy, B. A. & Bouhassira, E. E., Mar 5 2019, In : Cell Reports. 26, 10, p. 2580-2592.e7

Research output: Contribution to journalArticle

Open Access
Induced Pluripotent Stem Cells
Hematopoietic Stem Cells
Stem cells
Fibroblasts
Mutation
19 Citations (Scopus)

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

Carvajal, L. A., Ben Neriah, D., Senecal, A., Benard, L., Thiruthuvanathan, V., Yatsenko, T., Narayanagari, S-R., Wheat, J. C., Todorova, T. I., Mitchell, K., Kenworthy, C., Guerlavais, V., Annis, D. A., Bartholdy, B. A., Will, B., Anampa Mesias, J. D., Mantzaris, I., Aivado, M., Singer, R. H., Coleman, R. A. & 2 others, Verma, A. K. & Steidl, U. G., Apr 11 2018, In : Science Translational Medicine. 10, 436, aao3003.

Research output: Contribution to journalArticle

Leukemia
Acute Myeloid Leukemia
Neoplasms
Therapeutics
Cell Cycle Checkpoints