• 10405 Citations
  • 38 h-Index
19972020

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3β and a tumor suppressor in lung cancer

Huang, G., Eisenberg, R., Yan, M., Monti, S., Lawrence, E., Fu, P., Walbroehl, J., Löwenberg, E., Golub, T., Merchan, J., Tenen, D. G., Markowitz, S. D. & Halmos, B., Jul 1 2008, In : Cancer Research. 68, 13, p. 5040-5048 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Activating mutations of the Noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

Bentires-Alj, M., Paez, J. G., David, F. S., Keilhack, H., Halmos, B., Naoki, K., Maris, J. M., Richardson, A., Bardelli, A., Sagarbaker, D. J., Richards, W. G., Du, J., Girard, L., Minna, J. D., Loh, M. L., Fisher, D. E., Velculescu, V. E., Vogelstein, B., Meyerson, M., Sellers, W. R. & 1 others, Neel, B. G., Dec 15 2004, In : Cancer Research. 64, 24, p. 8816-8820 5 p.

Research output: Contribution to journalArticle

344 Scopus citations

Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

Zhang, Z., Lee, J. C., Lin, L., Olivas, V., Au, V., Laframboise, T., Abdel-Rahman, M., Wang, X., Levine, A. D., Rho, J. K., Choi, Y. J., Choi, C. M., Kim, S. W., Jang, S. J., Park, Y. S., Kim, W. S., Lee, D. H., Lee, J. S., Miller, V. A., Arcila, M. & 10 others, Ladanyi, M., Moonsamy, P., Sawyers, C., Boggon, T. J., Ma, P. C., Costa, C., Taron, M., Rosell, R., Halmos, B. & Bivona, T. G., Aug 1 2012, In : Nature Genetics. 44, 8, p. 852-860 9 p.

Research output: Contribution to journalArticle

685 Scopus citations

An alternative inhibitor overcomes resistance caused by a mutation of the epidermal growth factor receptor

Kobayashi, S., Ji, H., Yuza, Y., Meyerson, M., Wong, K. K., Tenen, D. G. & Halmos, B., Aug 15 2005, In : Cancer Research. 65, 16, p. 7096-7101 6 p.

Research output: Contribution to journalArticle

218 Scopus citations

An analysis of the relationship between metastases and cachexia in lung cancer patients

Shiono, M., Huang, K., Downey, R. J., Consul, N., Villanueva, N., Beck, K., Fenn, K., Dietz, D., Yamaguchi, T., Kato, S., Divgi, C., Kalinsky, K., Wei, Y., Zhang, Y., Borczuk, A. C., Inoue, A., Halmos, B. & Acharyya, S., Sep 1 2016, In : Cancer Medicine. 5, 9, p. 2641-2648 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

A Phase i Study of the combination of oxaliplatin/docetaxel and vandetanib for the treatment of advanced gastroesophageal cancer

Halmos, B., Jia, Y., Bokar, J. A., Fu, P., Adelstein, D. J., Juergens, R., Rodal, M. B. & Dowlati, A., Oct 1 2013, In : Investigational New Drugs. 31, 5, p. 1244-1250 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

A randomized, phase 2 trial of docetaxel with or without PX-866, an irreversible oral phosphatidylinositol 3-kinase inhibitor, in patients with relapsed or metastatic non-small-cell lung cancer

Levy, B., Spira, A., Becker, D., Evans, T., Schnadig, I., Camidge, D. R., Bauman, J. E., Hausman, D., Walker, L., Nemunaitis, J., Rudin, C. M., Halmos, B. & Bowles, D. W., Jul 2014, In : Journal of Thoracic Oncology. 9, 7, p. 1031-1035 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

A randomized phase 2 study of erlotinib alone and in combination with bortezomib in previously treated advanced non-small cell lung cancer

Lynch, T. J., Fenton, D., Hirsh, V., Bodkin, D., Middleman, E. L., Chiappori, A., Halmos, B., Favis, R., Liu, H., Trepicchio, W. L., Eton, O. & Shepherd, F. A., Aug 2009, In : Journal of Thoracic Oncology. 4, 8, p. 1002-1009 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening

Jänne, P. A., Borras, A. M., Kuang, Y., Rogers, A. M., Joshi, V. A., Liyanage, H., Lindeman, N., Lee, J. C., Halmos, B., Maher, E. A., Distel, R. J., Meyerson, M. & Johnson, B. E., Feb 1 2006, In : Clinical Cancer Research. 12, 3 I, p. 751-758 8 p.

Research output: Contribution to journalArticle

186 Scopus citations

Association of primary biliary cirrhosis with vitamin D receptor BsmI genotype polymorphism in a Hungarian population

Halmos, B., Szalay, F., Cserniczky, T., Nemesanszky, E., Lakatos, P., Barlage, S., Schmitz, G., Romics, L. & Csaszar, A., Jul 6 2000, In : Digestive Diseases and Sciences. 45, 6, p. 1091-1095 5 p.

Research output: Contribution to journalArticle

47 Scopus citations

A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3β as a novel tumor suppressor in lung cancer

Halmos, B., Bassères, D. S., Monti, S., D'Aló, F., Dayaram, T., Ferenczi, K., Wouters, B. J., Huettner, C. S., Golub, T. R. & Tenen, D. G., Jun 15 2004, In : Cancer Research. 64, 12, p. 4137-4147 11 p.

Research output: Contribution to journalArticle

55 Scopus citations

AXL

Halmos, B. & Liu, X. W., Jan 1 2017, Cancer Therapeutic Targets. Springer New York, Vol. 2-2. p. 661-671 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

AXL kinase as a novel target for cancer therapy

Wu, X., Liu, X., Koul, S., Lee, C. Y., Zhang, Z. & Halmos, B., Jan 1 2014, In : Oncotarget. 5, 20, p. 9546-9563 18 p.

Research output: Contribution to journalArticle

Open Access
103 Scopus citations

BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations

Costa, D. B., Halmos, B., Kumar, A., Schumer, S. T., Huberman, M. S., Boggon, T. J., Tenen, D. G. & Kobayashi, S., Oct 1 2007, In : PLoS Medicine. 4, 10, p. 1669-1680 12 p.

Research output: Contribution to journalArticle

373 Scopus citations

Biomarker use in lung cancer management: Expanding horizons

Sandler, J. E., Kaumaya, M. & Halmos, B., Apr 2018, In : Biomarkers in Medicine. 12, 4, p. 315-320 6 p.

Research output: Contribution to journalComment/debate

C/EBPα mutations in lung cancer

Costa, D. B., Dayaram, T., D'Alo, F., Wouters, B. J., Tenen, D. G., Meyerson, M., Tsao, M. S. & Halmos, B., Aug 1 2006, In : Lung Cancer. 53, 2, p. 253-254 2 p.

Research output: Contribution to journalLetter

14 Scopus citations

Cancer: Mechanisms of acquired crizotinib resistance in ALK-rearranged lung cancers

Katayama, R., Shaw, A. T., Khan, T. M., Mino-Kenudson, M., Solomon, B. J., Halmos, B., Jessop, N. A., Wain, J. C., Yeo, A. T., Benes, C., Drew, L., Saeh, J. C., Crosby, K., Sequist, L. V., Iafrate, A. J. & Engelman, J. A., Feb 8 2012, In : Science translational medicine. 4, 120

Research output: Contribution to journalArticle

840 Scopus citations

CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells

O'Brien, K. B., Alberich-Jordà, M., Yadav, N., Kocher, O., DiRuscio, A., Ebralidze, A., Levantini, E., Sng, N. J. L., Bhasin, M., Caron, T., Kim, D., Steidl, U., Huang, G., Halmos, B., Rodig, S. J., Bedford, M. T., Tenen, D. G. & Kobayashi, S., Jul 1 2010, In : Development. 137, 13, p. 2147-2156 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Case 4. Mutation of the epidermal growth factor receptor in an elderly man with advanced, gefitinib-responsive, non-small-cell lung cancer

Cho, D., Kocher, O., Tenen, D. G., Halmos, B., Lee, J. C., Meyerson, M. L. & Janne, P. A., Jan 1 2005, In : Journal of Clinical Oncology. 23, 1, p. 235-237 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Changes in store for early-stage non-small cell lung cancer

Sandler, J. E., D'Aiello, A. & Halmos, B., Jan 1 2019, In : Journal of Thoracic Disease. 11, 5, p. 2117-2125 9 p.

Research output: Contribution to journalReview article

1 Scopus citations

Characterization of 298 patients with lung cancer harboring MET Exon 14 skipping alterations

Schrock, A. B., Frampton, G. M., Suh, J., Chalmers, Z. R., Rosenzweig, M., Erlich, R. L., Halmos, B., Goldman, J., Forde, P., Leuenberger, K., Peled, N., Kalemkerian, G. P., Ross, J. S., Stephens, P. J., Miller, V. A., Ali, S. M. & Ou, S. H. I., Jan 1 2016, In : Journal of Thoracic Oncology. 11, 9, p. 1493-1502 10 p.

Research output: Contribution to journalArticle

92 Scopus citations

Circulating tumor DNA in non-small-cell lung cancer: A primer for the clinician

Singh, A. P., Cheng, H., Guo, X., Levy, B. & Halmos, B., Jan 1 2017, In : JCO Precision Oncology. 2017, 1, p. 1-13 13 p.

Research output: Contribution to journalReview article

8 Scopus citations

Colonic epithelial cell proliferation decreases with increasing levels of serum 25-hydroxy vitamin D

Holt, P. R., Arber, N., Halmos, B., Kissileff, H., Moss, S. F., Holt, P. R., Arber, N., Halmos, B., Kissileff, H., Moss, S. F., Forde, K., McGlynn, K. A., Fan, K., Yang, K. & Lipkin, M., Jan 1 2002, In : Cancer Epidemiology Biomarkers and Prevention. 11, 1, p. 113-119 7 p.

Research output: Contribution to journalArticle

132 Scopus citations

Combined histone deacetylase and cyclooxygenase inhibition achieves enhanced antiangiogenic effects in lung cancer cells

Wang, X., Li, G., Wang, A., Zhang, Z., Merchan, J. R. & Halmos, B., Mar 1 2013, In : Molecular Carcinogenesis. 52, 3, p. 218-228 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Combined vascular endothelial growth factor receptor and Epidermal Growth Factor Receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance

Naumov, G. N., Nilsson, M. B., Cascone, T., Briggs, A., Straume, O., Akslen, L. A., Lifshits, E., Byers, L. A., Xu, L., Wu, H. K., Jänne, P., Kobayashi, S., Halmos, B., Tenen, D., Tang, X. M., Engelman, J., Yeap, B., Folkman, J., Johnson, B. E. & Heymach, J. V., May 15 2009, In : Clinical Cancer Research. 15, 10, p. 3484-3494 11 p.

Research output: Contribution to journalArticle

203 Scopus citations

Complete pathological response in a patient with metastatic esophageal cancer treated with a regimen of capecitabine, oxaliplatin and docetaxel: a case report

Seetharamu, N., Melamed, J., Miller, G., Rotterdam, H., Gonda, T., Villanueva, G. & Halmos, B., Dec 1 2014, In : Journal of Gastrointestinal Cancer. 45, p. 108-111 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
8 Scopus citations

Cooperative interaction between protein inhibitor of activated signal transducer and activator of transcription-3 with epidermal growth factor receptor blockade in lung cancer

Kluge, A., Dabir, S., Kern, J., Nethery, D., Halmos, B., Ma, P. & Dowlati, A., Oct 1 2009, In : International Journal of Cancer. 125, 7, p. 1728-1734 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

CTCs - Ready to take center stage?

Halmos, B., Jul 1 2009, In : American Journal of Hematology/ Oncology. 8, 7

Research output: Contribution to journalComment/debate

1 Scopus citations

Differential effects of gefitinib and cetuximab on non-small-cell lung cancers bearing epidermal growth factor receptor mutations

Mukohara, T., Engelman, J. A., Hanna, N. H., Yeap, B. Y., Kobayashi, S., Lindeman, N., Halmos, B., Pearlberg, J., Tsuchihashi, Z., Cantley, L. C., Tenen, D. G., Johnson, B. E. & Jänne, P. A., Aug 1 2005, In : Journal of the National Cancer Institute. 97, 16, p. 1185-1194 10 p.

Research output: Contribution to journalArticle

271 Scopus citations

Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity

Tang, Z., Jiang, S., Du, R., Petri, E. T., El-Telbany, A., Chan, P. S. O., Kijima, T., Dietrich, S., Matsui, K., Kobayashi, M., Sasada, S., Okamoto, N., Suzuki, H., Kawahara, K., Iwasaki, T., Nakagawa, K., Kawase, I., Christensen, J. G., Hirashima, T., Halmos, B. & 4 others, Salgia, R., Boggon, T. J., Kern, J. A. & Ma, P. C., Jan 29 2009, In : Oncogene. 28, 4, p. 518-533 16 p.

Research output: Contribution to journalArticle

14 Scopus citations

DNA polymerase ε deficiency leading to an ultramutator phenotype: A novel clinically relevant entity

Castellucci, E., He, T., Goldstein, D. Y., Halmos, B. & Chuy, J., May 2017, In : Oncologist. 22, 5, p. 497-502 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Does lung cancer mutation status and targeted therapy predict for outcomes and local control in the setting of brain metastases treated with radiation?

Wang, T. J. C., Saad, S., Qureshi, Y. H., Jani, A., Nanda, T., Yaeh, A. M., Rozenblat, T., Sisti, M. B., Bruce, J. N., McKhann, G. M., Lesser, J., Halmos, B., Stoopler, M. B., Lassman, A. B., Cheng, S. K. & Isaacson, S. R., Jul 1 2015, In : Neuro-Oncology. 17, 7, p. 1022-1028 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Down-regulation and antiproliferative role of C/EBPα in lung cancer

Halmos, B., Karp, D. D., Kocher, O., Huettner, C. S., Tenen, D. G. & Ferenczi, K., Jan 15 2002, In : Cancer Research. 62, 2, p. 528-534 7 p.

Research output: Contribution to journalArticle

108 Scopus citations

Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer

Tang, Z., Du, R., Jiang, S., Wu, C., Barkauskas, D. S., Richey, J., Molter, J., Lam, M., Flask, C., Gerson, S., Dowlati, A., Liu, L., Lee, Z., Halmos, B., Wang, Y., Kern, J. A. & Ma, P. C., Sep 16 2008, In : British Journal of Cancer. 99, 6, p. 911-922 12 p.

Research output: Contribution to journalArticle

140 Scopus citations

Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells

Zhang, Z., Kobayashi, S., Borczuk, A. C., Leidner, R. S., LaFramboise, T., Levine, A. D. & Halmos, B., Jan 22 2010, In : Carcinogenesis. 31, 4, p. 577-586 10 p.

Research output: Contribution to journalArticle

111 Scopus citations

Dysregulation of the C/EBPα differentiation pathway in human cancer

Koschmieder, S., Halmos, B., Levantini, E. & Tenen, D. G., Feb 1 2009, In : Journal of Clinical Oncology. 27, 4, p. 619-628 10 p.

Research output: Contribution to journalReview article

140 Scopus citations

Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib

Costa, D. B., Nguyen, K. S. H., Cho, B. C., Sequist, L. V., Jackman, D. M., Riely, G. J., Yeap, B. Y., Halmos, B., Kim, J. H., Jänne, P. A., Huberman, M. S., Pao, W., Tenen, D. G. & Kobayashi, S., Nov 1 2008, In : Clinical Cancer Research. 14, 21, p. 7060-7067 8 p.

Research output: Contribution to journalArticle

146 Scopus citations

EGFR molecular testing in African-American non-small cell lung cancer patients - A review of discrepant data

Clifford, B. T., Fu, P., Pennell, N. A., Halmos, B. & Leidner, R. S., 2013, In : Translational Lung Cancer Research. 2, 3, p. 251-255 5 p.

Research output: Contribution to journalReview article

8 Scopus citations

EGFR-mutated lung cancer: a paradigm of molecular oncology.

Zhang, Z., Stiegler, A. L., Boggon, T. J., Kobayashi, S. & Halmos, B., Nov 2010, In : Oncotarget. 1, 7, p. 497-514 18 p.

Research output: Contribution to journalReview article

Open Access
140 Scopus citations

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

Kobayashi, S., Boggon, T. J., Dayaram, T., Jänne, P. A., Kocher, O., Meyerson, M., Johnson, B. E., Eck, M. J., Tenen, D. G. & Halmos, B., Feb 24 2005, In : New England Journal of Medicine. 352, 8, p. 786-792 7 p.

Research output: Contribution to journalArticle

2978 Scopus citations

EGFR mutation and response of lung cancer to gefitinib [3] (multiple letters)

Toyooka, S., Kiura, K., Mitsudomi, T., Kobayashi, S., Tenen, D. G. & Halmos, B., May 19 2005, In : New England Journal of Medicine. 352, 20, 1 p.

Research output: Contribution to journalLetter

101 Scopus citations

EGFR T790M: Revealing the secrets of a gatekeeper

Ko, B., Paucar, D. & Halmos, B., Oct 9 2017, In : Lung Cancer: Targets and Therapy. 8, p. 147-159 13 p.

Research output: Contribution to journalReview article

9 Scopus citations

Emerging uses of biomarkers in lung cancer management

Halmos, B. & Levy, B., Sep 1 2017, In : Annals of Translational Medicine. 5, 18, 370.

Research output: Contribution to journalArticle

2 Scopus citations

Emerging uses of biomarkers in lung cancer management: Molecular mechanisms of resistance

Attarian, S., Rahman, N. & Halmos, B., Sep 1 2017, In : Annals of Translational Medicine. 5, 18, 377.

Research output: Contribution to journalArticle

8 Scopus citations

Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib

Jackman, D. M., Yeap, B. Y., Sequist, L. V., Lindeman, N., Holmes, A. J., Joshi, V. A., Bell, D. W., Huberman, M. S., Halmos, B., Rabin, M. S., Haber, D. A., Lynch, T. J., Meyerson, M., Johnson, B. E. & Jänne, P. A., Jul 1 2006, In : Clinical Cancer Research. 12, 13, p. 3908-3914 7 p.

Research output: Contribution to journalArticle

455 Scopus citations