• 10572 Citations
  • 39 h-Index
19972020

Research output per year

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Publications

2020

Impact and diagnostic gaps of comprehensive genomic profiling in real-world clinical practice

Singh, A. P., Shum, E., Rajdev, L., Cheng, H., Goel, S., Perez-Soler, R. & Halmos, B., May 2020, In : Cancers. 12, 5, 1156.

Research output: Contribution to journalArticle

Open Access

Survival Disparities in Black Patients With EGFR-mutated Non–small-cell Lung Cancer

Cheng, H., Hosgood, H. D., Deng, L., Ye, K., Su, C., Sharma, J., Yang, Y., Halmos, B. & Perez-Soler, R., Mar 2020, In : Clinical lung cancer. 21, 2, p. 177-185 9 p.

Research output: Contribution to journalArticle

The evolving use of pembrolizumab in combination treatment approaches for non-small cell lung cancer

Alexander, M., Ko, B., Lambert, R., Gadgeel, S. & Halmos, B., Feb 1 2020, In : Expert Review of Respiratory Medicine. 14, 2, p. 137-147 11 p.

Research output: Contribution to journalArticle

2019

Changes in store for early-stage non-small cell lung cancer

Sandler, J. E., D'Aiello, A. & Halmos, B., Jan 1 2019, In : Journal of Thoracic Disease. 11, 5, p. 2117-2125 9 p.

Research output: Contribution to journalReview article

1 Scopus citations
1 Scopus citations

Immune Checkpoint Blockade Is Associated With Durable Responses in Pulmonary Sarcomatoid Carcinoma

Sukrithan, V., Sandler, J., Gucalp, R., Gralla, R. & Halmos, B., May 2019, In : Clinical lung cancer. 20, 3, p. e242-e246

Research output: Contribution to journalArticle

2 Scopus citations

Impact of afatinib dose modification on safety and effectiveness in patients with EGFR mutation-positive advanced NSCLC: Results from a global real-world study (RealGiDo)

Halmos, B., Tan, E. H., Soo, R. A., Cadranel, J., Lee, M. K., Foucher, P., Hsia, T. C., Hochmair, M., Griesinger, F., Hida, T., Kim, E., Melosky, B., Märten, A. & Carcereny, E., Jan 2019, In : Lung Cancer. 127, p. 103-111 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
1 Scopus citations

Local consolidative therapy in metastatic non-small cell lung cancer

Patel, G., Halmos, B., Cheng, H. & Ohri, N., Jan 1 2019, In : Journal of Thoracic Disease. 11, p. S1909-S1912

Research output: Contribution to journalComment/debate

Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study

Burtness, B., Harrington, K. J., Greil, R., Soulières, D., Tahara, M., de Castro, G., Psyrri, A., Basté, N., Neupane, P., Bratland, Å., Fuereder, T., Hughes, B. G. M., Mesía, R., Ngamphaiboon, N., Rordorf, T., Wan Ishak, W. Z., Hong, R. L., González Mendoza, R., Roy, A., Zhang, Y. & 188 others, Gumuscu, B., Cheng, J. D., Jin, F., Rischin, D., Lerzo, G., Tatangelo, M., Varela, M., Zarba, J. J., Boyer, M., Gan, H., Gao, B., Hughes, B., Mallesara, G., Taylor, A., Burian, M., Barrios, C. H., de Castro Junior, D. O., Castro, G., Franke, F. A., Girotto, G., Lima, I. P. F., Nicolau, U. R., Pinto, G. D. J., Santos, L., Victorino, A. P., Chua, N., Couture, F., Gregg, R., Hansen, A., Hilton, J., McCarthy, J., Soulieres, D., Ascui, R., Gonzalez, P., Villanueva, L., Torregroza, M., Zambrano, A., Holeckova, P., Kral, Z., Melichar, B., Prausova, J., Vosmik, M., Andersen, M., Gyldenkerne, N., Jurgens, H., Putnik, K., Reinikainen, P., Gruenwald, V., Laban, S., Aravantinos, G., Boukovinas, I., Georgoulias, V., Kwong, D., Al-Farhat, Y., Csoszi, T., Erfan, J., Horvai, G., Landherr, L., Remenar, E., Ruzsa, A., Szota, J., Billan, S., Gluck, I., Gutfeld, O., Popovtzer, A., Benasso, M., Bui, S., Ferrari, V., Licitra, L., Nole, F., Fujii, T., Fujimoto, Y., Hanai, N., Hara, H., Matsumoto, K., Mitsugi, K., Monden, N., Nakayama, M., Okami, K., Oridate, N., Shiga, K., Shimizu, Y., Sugasawa, M., Takahashi, M., Takahashi, S., Tanaka, K., Ueda, T., Yamaguchi, H., Yamazaki, T., Yasumatsu, R., Yokota, T., Yoshizaki, T., Kudaba, I., Stara, Z., Cheah, S. K., Aguilar Ponce, J., Gonzalez Mendoza, R., Hernandez Hernandez, C., Medina Soto, F., Buter, J., Hoeben, A., Oosting, S., Suijkerbuijk, K., Bratland, A., Brydoey, M., Alvarez, R., Mas, L., Caguioa, P., Querol, J., Regala, E. E., Tamayo, M. B., Villegas, E. M., Kawecki, A., Karpenko, A., Klochikhin, A., Smolin, A., Zarubenkov, O., Goh, B. C., Cohen, G., du Toit, J., Jordaan, C., Landers, G., Ruff, P., Szpak, W., Tabane, N., Brana, I., Iglesias Docampo, L., Lavernia, J., Mesia, R., Abel, E., Muratidu, V., Nielsen, N., Cristina, V., Rothschild, S., Wang, H. M., Yang, M. H., Yeh, S. P., Yen, C. J., Soparattanapaisarn, N., Sriuranpong, V., Aksoy, S., Cicin, I., Ekenel, M., Harputluoglu, H., Ozyilkan, O., Harrington, K., Agarwala, S., Ali, H., Alter, R., Anderson, D., Bruce, J., Campbell, N., Conde, M., Deeken, J., Edenfield, W., Feldman, L., Gaughan, E., Goueli, B., Halmos, B., Hegde, U., Hunis, B., Jotte, R., Karnad, A., Khan, S., Laudi, N., Laux, D., Martincic, D., McCune, S., McGaughey, D., Misiukiewicz, K., Mulford, D., Nadler, E., Nunnink, J., Ohr, J., O'Malley, M., Patson, B., Paul, D., Popa, E., Powell, S., Redman, R., Rella, V., Rocha Lima, C., Sivapiragasam, A., Su, Y., Sukari, A., Wong, S., Yilmaz, E. & Yorio, J., Nov 23 2019, In : The Lancet. 394, 10212, p. 1915-1928 14 p.

Research output: Contribution to journalArticle

50 Scopus citations

Sequencing therapies in oncogene-driven non-small-cell lung cancer: How to get the best mileage?

Sukrithan, V., Snyder, R., Cheng, H. & Halmos, B., Jan 1 2019, In : Future Oncology. 15, 25, p. 2899-2904 6 p.

Research output: Contribution to journalReview article

1 Scopus citations

Sequential afatinib and osimertinib in patients with EGFR mutation-positive non-small-cell lung cancer: Updated analysis of the observational GioTag study

Hochmair, M. J., Morabito, A., Hao, D., Yang, C. T., Soo, R. A., Yang, J. C. H., Gucalp, R., Halmos, B., Wang, L., Märten, A. & Cufer, T., Jan 1 2019, In : Future Oncology. 15, 25, p. 2905-2914 10 p.

Research output: Contribution to journalReview article

Open Access
12 Scopus citations
2018

Biomarker use in lung cancer management: Expanding horizons

Sandler, J. E., Kaumaya, M. & Halmos, B., Apr 2018, In : Biomarkers in Medicine. 12, 4, p. 315-320 6 p.

Research output: Contribution to journalComment/debate

Expanding the gamut of circulating tumor DNA applications

Kaumaya, M. & Halmos, B., Nov 1 2018, In : Journal of Thoracic Disease. 10, p. S4151-S4155

Research output: Contribution to journalReview article

1 Scopus citations

Molecular testing in lung cancer: Where to draw the line?

Halmos, B., Jul 2018, In : Archives of Pathology and Laboratory Medicine. 142, 7, p. 787-789 3 p.

Research output: Contribution to journalComment/debate

Pembrolizumab plus Chemotherapy for Squamous Non-Small-Cell Lung Cancer

KEYNOTE-407 Investigators, Nov 22 2018, In : The New England journal of medicine. 379, 21, p. 2040-2051 12 p.

Research output: Contribution to journalArticle

507 Scopus citations

Phase II Study of Maintenance Pembrolizumab in Patients with Extensive-Stage Small Cell Lung Cancer (SCLC)

Gadgeel, S. M., Pennell, N. A., Fidler, M. J., Halmos, B., Bonomi, P., Stevenson, J., Schneider, B., Sukari, A., Ventimiglia, J., Chen, W., Galasso, C., Wozniak, A., Boerner, J. & Kalemkerian, G. P., Jan 1 2018, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

42 Scopus citations

PHLDA2 is a key oncogene-induced negative feedback inhibitor of EGFR/ErbB2 signaling via interference with AKT signaling

Wang, X., Li, G., Koul, S., Ohki, R., Maurer, M., Borczuk, A. & Halmos, B., May 18 2018, In : Oncotarget. 9, 38, p. 24914-24926 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
1 Scopus citations

Sequential treatment with afatinib and osimertinib in patients with EGFR mutation-positive non-small-cell lung cancer: An observational study

Hochmair, M. J., Morabito, A., Hao, D., Yang, C. T., Soo, R. A., Yang, J. C. H., Gucalp, R., Halmos, B., Wang, L., Golembesky, A., Märten, A. & Cufer, T., Nov 2018, In : Future Oncology. 14, 27, p. 2861-2874 14 p.

Research output: Contribution to journalArticle

37 Scopus citations

Wide expression and significance of alternative immune checkpoint molecules, B7x and HHLA2, in PD-L1–negative human lung cancers

Cheng, H., Borczuk, A., Janakiram, M., Ren, X., Lin, J., Assal, A., Halmos, B., Perez-Soler, R. & Zang, X., Apr 15 2018, In : Clinical Cancer Research. 24, 8, p. 1954-1964 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

AXL

Halmos, B. & Liu, X. W., Jan 1 2017, Cancer Therapeutic Targets. Springer New York, Vol. 2-2. p. 661-671 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Circulating tumor DNA in non-small-cell lung cancer: A primer for the clinician

Singh, A. P., Cheng, H., Guo, X., Levy, B. & Halmos, B., Jan 1 2017, In : JCO Precision Oncology. 2017, 1, p. 1-13 13 p.

Research output: Contribution to journalReview article

8 Scopus citations
8 Scopus citations

DNA polymerase ε deficiency leading to an ultramutator phenotype: A novel clinically relevant entity

Castellucci, E., He, T., Goldstein, D. Y., Halmos, B. & Chuy, J., May 2017, In : Oncologist. 22, 5, p. 497-502 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

EGFR T790M: Revealing the secrets of a gatekeeper

Ko, B., Paucar, D. & Halmos, B., Oct 9 2017, In : Lung Cancer: Targets and Therapy. 8, p. 147-159 13 p.

Research output: Contribution to journalReview article

9 Scopus citations

Emerging uses of biomarkers in lung cancer management

Halmos, B. & Levy, B., Sep 1 2017, In : Annals of Translational Medicine. 5, 18, 370.

Research output: Contribution to journalArticle

2 Scopus citations

Emerging uses of biomarkers in lung cancer management: Molecular mechanisms of resistance

Attarian, S., Rahman, N. & Halmos, B., Sep 1 2017, In : Annals of Translational Medicine. 5, 18, 377.

Research output: Contribution to journalArticle

8 Scopus citations

HHLA2, a new immune checkpoint member of the B7 family, is widely expressed in human lung cancer and associated with EGFR mutational status

Cheng, H., Janakiram, M., Borczuk, A., Lin, J., Qiu, W., Liu, H., Chinai, J. M., Halmos, B., Perez-Soler, R. & Zang, X., Feb 1 2017, In : Clinical Cancer Research. 23, 3, p. 825-832 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Interaction of treatment and biomarker in advanced non-small cell lung cancer

Fu, P., Pennell, N. A., Sharma, N., Yi, Q., Dowlati, A. & Halmos, B., Mar 1 2017, In : Reviews on Recent Clinical Trials. 12, 1, p. 51-58 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

MET

Asmar, R. & Halmos, B., Jan 1 2017, Cancer Therapeutic Targets. Springer New York, Vol. 2-2. p. 773-786 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

MET/HGF pathway activation as a paradigm of resistance to targeted therapies

Ko, B., He, T., Gadgeel, S. & Halmos, B., Jan 1 2017, In : Annals of Translational Medicine. 5, 1, 4.

Research output: Contribution to journalReview article

19 Scopus citations

MET–GRB2 signaling-associated complexes correlate with oncogenic MET signaling and sensitivity to MET kinase inhibitors

Smith, M. A., Licata, T., Lakhani, A., Garcia, M. V., Schildhaus, H. U., Vuaroqueaux, V., Halmos, B., Borczuk, A. C., Chen, Y. A., Creelan, B. C., Boyle, T. A. & Haura, E. B., Nov 15 2017, In : Clinical Cancer Research. 23, 22, p. 7084-7096 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Mutant allele specific imbalance in oncogenes with copy number alterations: Occurrence, mechanisms, and potential clinical implications

Yu, C. C., Qiu, W., Juang, C. S., Mansukhani, M. M., Halmos, B. & Su, G. H., Jan 1 2017, In : Cancer Letters. 384, p. 86-93 8 p.

Research output: Contribution to journalShort survey

10 Scopus citations

Pulmonary Sarcomatoid Carcinomas Commonly Harbor Either Potentially Targetable Genomic Alterations or High Tumor Mutational Burden as Observed by Comprehensive Genomic Profiling

Schrock, A. B., Li, S. D., Frampton, G. M., Suh, J., Braun, E., Mehra, R., Buck, S. C., Bufill, J. A., Peled, N., Karim, N. A., Hsieh, K. C., Doria, M., Knost, J., Chen, R., Ou, S. H. I., Ross, J. S., Stephens, P. J., Fishkin, P., Miller, V. A., Ali, S. M. & 2 others, Halmos, B. & Liu, J. J., Jun 2017, In : Journal of Thoracic Oncology. 12, 6, p. 932-942 11 p.

Research output: Contribution to journalArticle

45 Scopus citations
2016

An analysis of the relationship between metastases and cachexia in lung cancer patients

Shiono, M., Huang, K., Downey, R. J., Consul, N., Villanueva, N., Beck, K., Fenn, K., Dietz, D., Yamaguchi, T., Kato, S., Divgi, C., Kalinsky, K., Wei, Y., Zhang, Y., Borczuk, A. C., Inoue, A., Halmos, B. & Acharyya, S., Sep 1 2016, In : Cancer Medicine. 5, 9, p. 2641-2648 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells

Cheng, H., Zhang, Z., Rodriguez-Barrueco, R. R., Borczuk, A., Liu, H., Yu, J., Silva, J. M., Cheng, S. K., Perez-Soler, R. & Halmos, B., May 17 2016, In : Oncotarget. 7, 20, p. 28976-28988 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

Has MET met its match?

Borczuk, A., Paucar, D. & Halmos, B., Mar 2016, In : Annals of Translational Medicine. 4, 5, 97.

Research output: Contribution to journalEditorial

5 Scopus citations

High prevalence and allele burden-independent prognostic importance of p53 mutations in an inner-city MDS/AML cohort

Goel, S., Hall, J., Pradhan, K., Hirsch, C., Przychodzen, B., Shastri, A., Mantzaris, I., Janakiram, M., Battini, R., Kornblum, N., Derman, O., Gritsman, K., Al-Hafidh, J., Wang, Y., Halmos, B., Steidl, U. G., Maciejewski, J. P., Braunschweig, I. & Verma, A. K., Apr 29 2016, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

12 Scopus citations

Marked differences in CNS activity among EGFR inhibitors: Case report and mini-review

Pareek, V., Welch, M., Ravera, E., Zampolin, R. L., Sequist, L. V. & Halmos, B., Nov 13 2016, In : Journal of Thoracic Oncology. 11, 11, p. e135-e139

Research output: Contribution to journalArticle

8 Scopus citations

New twists in the AXL(e) of tumor progression

Halmos, B. & Haura, E. B., Oct 4 2016, In : Science Signaling. 9, 448, fs14.

Research output: Contribution to journalArticle

6 Scopus citations

Next-generation sequencing of pulmonary sarcomatoid carcinoma reveals high frequency of actionable MET gene mutations

Liu, X., Jia, Y., Stoopler, M. B., Shen, Y., Cheng, H., Chen, J., Mansukhani, M., Koul, S., Halmos, B. & Borczuk, A. C., Mar 10 2016, In : Journal of Clinical Oncology. 34, 8, p. 794-802 9 p.

Research output: Contribution to journalArticle

143 Scopus citations

Recent advances in the management of pulmonary sarcomatoid carcinoma

Shum, E., Stuart, M., Borczuk, A., Wang, F., Cheng, H. & Halmos, B., Apr 2 2016, In : Expert Review of Respiratory Medicine. 10, 4, p. 407-416 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Sunitinib activates Axl signaling in renal cell cancer

Van Der Mijn, J. C., Broxterman, H. J., Knol, J. C., Piersma, S. R., De Haas, R. R., Dekker, H., Pham, T. V., Van Beusechem, V. W., Halmos, B., Mier, J. W., Jiménez, C. R. & Verheul, H. M. W., Jun 15 2016, In : International Journal of Cancer. 138, 12, p. 3002-3010 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Targeted BMI1 inhibition impairs tumor growth in lung adenocarcinomas with low CEBPα expression

Yong, K. J., Basseres, D. S., Welner, R. S., Zhang, W. C., Yang, H., Yan, B., Alberich-Jorda, M., Zhang, J., De Figueiredo-Pontes, L. L., Battelli, C., Hetherington, C. J., Ye, M., Zhang, H., Maroni, G., O'Brien, K., Magli, M. C., Borczuk, A. C., Varticovski, L., Kocher, O., Zhang, P. & 12 others, Moon, Y. C., Sydorenko, N., Cao, L., Davis, T. W., Thakkar, B. M., Soo, R. A., Iwama, A., Lim, B., Halmos, B., Neuberg, D., Tenen, D. G. & Levantini, E., Aug 3 2016, In : Science Translational Medicine. 8, 350, p. 350ra104

Research output: Contribution to journalArticle

26 Scopus citations