• 4683 Citations
  • 33 h-Index
1987 …2020

Research output per year

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Publications

2020

Macrophages use a bet-hedging strategy for antimicrobial activity in phagolysosomal acidification

Dragotakes, Q., Stouffer, K. M., Fu, M. S., Sella, Y., Youn, C., Yoon, O. I., de Leon-Rodriguez, C. M., Freij, J. B., Bergman, A. & Casadevall, A., Jul 1 2020, In : Journal of Clinical Investigation. 130, 7, p. 3805-3819 15 p.

Research output: Contribution to journalArticle

Open Access

Oscillations in U.S. COVID-19 incidence and mortality data reflect diagnostic and reporting factors

Bergman, A., Sella, Y., Agre, P. & Casadevall, A., Aug 2020, In : mSystems. 5, 4, e00544-20.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

Mutation of the ATPase domain of mutS homolog-5 (MSH5) reveals a requirement for a functional MutSG complex for all crossovers in mammalian meiosis

Milano, C. R., Kim Holloway, J., Zhang, Y., Jin, B., Smith, C., Bergman, A., Edelmann, W. & Cohen, P. E., 2019, In : G3: Genes, Genomes, Genetics. 9, 6, p. 1839-1850 12 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2018

ECM Cross-Linking Regulates Invadopodia Dynamics

Pourfarhangi, K. E., Bergman, A. & Gligorijevic, B., Mar 27 2018, In : Biophysical journal. 114, 6, p. 1455-1466 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Real-time imaging of invadopodia in tumor microenvironment context

Bergman, A. & Gligorijevic, B., Jan 1 2018, Microscopy Histopathology and Analytics, MICROSCOPY 2018. OSA - The Optical Society, Vol. Part F89-MICROSCOPY 2018.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Self-organization by simulated evolution

Bergman, A., Jan 1 2018, Pattern Formation in the Physical and Biological Sciences. CRC Press, p. 13-21 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

The evolutionary dynamics of metabolic protocells

Pechuan, X., Puzio, R. & Bergman, A., Jul 2018, In : PLoS Computational Biology. 14, 7, e1006265.

Research output: Contribution to journalArticle

2017

Integrating live-cell fluorescent microscopy and signal processing to discover the relationship of invadopodia digging cycles with extracellular matrix crosslinking ratio

Pourfarhangi, K. E., Bergman, A. & Gligorijevic, B., Feb 7 2017, 2016 IEEE Signal Processing in Medicine and Biology Symposium, SPMB 2016 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 7846865

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations
2016

Fetal liver hematopoietic stem cell niches associate with portal vessels

Khan, J. A., Mendelson, A., Kunisaki, Y., Birbrair, A., Kou, Y., Arnal-Estapé, A., Pinho, S., Ciero, P., Nakahara, F., Ma'ayan, A., Bergman, A., Merad, M. & Frenette, P. S., 2016, In : Science. 351, 6269, p. 176-180 5 p.

Research output: Contribution to journalArticle

100 Scopus citations

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

Barban, N., Jansen, R., De Vlaming, R., Vaez, A., Mandemakers, J. J., Tropf, F. C., Shen, X., Wilson, J. F., Chasman, D. I., Nolte, I. M., Tragante, V., Van Der Laan, S. W., Perry, J. R. B., Kong, A., Ahluwalia, T. S., Albrecht, E., Yerges-Armstrong, L., Atzmon, G., Auro, K., Ayers, K. & 233 others, Bakshi, A., Ben-Avraham, D., Berger, K., Bergman, A., Bertram, L., Bielak, L. F., Bjornsdottir, G., Bonder, M. J., Broer, L., Bui, M., Barbieri, C., Cavadino, A., Chavarro, J. E., Turman, C., Concas, M. P., Cordell, H. J., Davies, G., Eibich, P., Eriksson, N., Esko, T., Eriksson, J., Falahi, F., Felix, J. F., Fontana, M. A., Franke, L., Gandin, I., Gaskins, A. J., Gieger, C., Gunderson, E. P., Guo, X., Hayward, C., He, C., Hofer, E., Huang, H., Joshi, P. K., Kanoni, S., Karlsson, R., Kiechl, S., Kifley, A., Kluttig, A., Kraft, P., Lagou, V., Lecoeur, C., Lahti, J., Li-Gao, R., Lind, P. A., Liu, T., Makalic, E., Mamasoula, C., Matteson, L., Mbarek, H., McArdle, P. F., McMahon, G., Meddens, S. F. W., Mihailov, E., Miller, M., Missmer, S. A., Monnereau, C., Van Der Most, P. J., Myhre, R., Nalls, M. A., Nutile, T., Kalafati, I. P., Porcu, E., Prokopenko, I., Rajan, K. B., Rich-Edwards, J., Rietveld, C. A., Robino, A., Rose, L. M., Rueedi, R., Ryan, K. A., Saba, Y., Schmidt, D., Smith, J. A., Stolk, L., Streeten, E., Tönjes, A., Thorleifsson, G., Ulivi, S., Wedenoja, J., Wellmann, J., Willeit, P., Yao, J., Yengo, L., Zhao, J. H., Zhao, W., Zhernakova, D. V., Amin, N., Andrews, H., Balkau, B., Barzilai, N., Bergmann, S., Biino, G., Bisgaard, H., Bønnelykke, K., Boomsma, D. I., Buring, J. E., Campbell, H., Cappellani, S., Ciullo, M., Cox, S. R., Cucca, F., Toniolo, D., Davey-Smith, G., Deary, I. J., Dedoussis, G., Deloukas, P., Van Duijn, C. M., De Geus, E. J. C., Eriksson, J. G., Evans, D. A., Faul, J. D., Sala, C. F., Froguel, P., Gasparini, P., Girotto, G., Grabe, H. J., Greiser, K. H., Groenen, P. J. F., De Haan, H. G., Haerting, J., Harris, T. B., Heath, A. C., Heikkilä, K., Hofman, A., Homuth, G., Holliday, E. G., Hopper, J., Hyppönen, E., Jacobsson, B., Jaddoe, V. W. V., Johannesson, M., Jugessur, A., Kähönen, M., Kajantie, E., Kardia, S. L. R., Keavney, B., Kolcic, I., Koponen, P., Kovacs, P., Kronenberg, F., Kutalik, Z., La Bianca, M., Lachance, G., Iacono, W. G., Lai, S., Lehtimäki, T., Liewald, D. C., Lindgren, C. M., Liu, Y., Luben, R., Lucht, M., Luoto, R., Magnus, P., Magnusson, P., Martin, N. G., McGue, M., McQuillan, R., Medland, S. E., Meisinger, C., Mellström, D., Metspalu, A., Traglia, M., Milani, L., Mitchell, P., Montgomery, G. W., Mook-Kanamori, D., De Mutsert, R., Nohr, E. A., Ohlsson, C., Olsen, J., Ong, K. K., Paternoster, L., Pattie, A., Penninx, B. W. J. H., Perola, M., Peyser, P. A., Pirastu, M., Polasek, O., Power, C., Kaprio, J., Raffel, L. J., Räikkönen, K., Raitakari, O., Ridker, P. M., Ring, S. M., Roll, K., Rudan, I., Ruggiero, D., Rujescu, D., Salomaa, V., Schlessinger, D., Schmidt, H., Schmidt, R., Schupf, N., Smit, J., Sorice, R., Spector, T. D., Starr, J. M., Stöckl, D., Strauch, K., Stumvoll, M., Swertz, M. A., Thorsteinsdottir, U., Roy Thurik, A., Timpson, N. J., Tung, J. Y., Uitterlinden, A. G., Vaccargiu, S., Viikari, J., Vitart, V., Völzke, H., Vollenweider, P., Vuckovic, D., Waage, J., Wagner, G. G., Wang, J. J., Wareham, N. J., Weir, D. R., Willemsen, G., Willeit, J., Wright, A. F., Zondervan, K. T., Stefansson, K., Krueger, R. F., Lee, J. J., Benjamin, D. J., Cesarini, D., Koellinger, P. D., Den Hoed, M., Snieder, H. & Mills, M. C., Oct 31 2016, In : Nature Genetics. 48, 12, p. 1-7 7 p.

Research output: Contribution to journalArticle

78 Scopus citations

The origin and evolution of cell types

Arendt, D., Musser, J. M., Baker, C. V. H., Bergman, A., Cepko, C., Erwin, D. H., Pavlicev, M., Schlosser, G., Widder, S., Laubichler, M. D. & Wagner, G. P., Dec 1 2016, In : Nature Reviews Genetics. 17, 12, p. 744-757 14 p.

Research output: Contribution to journalReview article

151 Scopus citations
2015
3 Scopus citations

Niche construction game cancer cells play

Bergman, A. & Gligorijevic, B., Oct 1 2015, In : European Physical Journal Plus. 130, 10, 203.

Research output: Contribution to journalReview article

3 Scopus citations

Overlapping hotspots in CDRs are critical sites for V region diversification

Wei, L., Chahwan, R., Wang, S., Wang, X., Pham, P. T., Goodman, M. F., Bergman, A., Scharff, M. D. & MacCarthy, T., Feb 17 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 7, p. E728-E737

Research output: Contribution to journalArticle

26 Scopus citations

Potential unsatisfiability of cyclic constraints on stochastic biological networks biases selection towards hierarchical architectures

Smith, C., Pechuan, X., Puzio, R. S., Biro, D. & Bergman, A., Jul 6 2015, In : Journal of the Royal Society Interface. 12, 108, 0179.

Research output: Contribution to journalArticle

2 Scopus citations

Systems biology of aging

Bolt, K. & Bergman, A., Jan 1 2015, In : Advances in experimental medicine and biology. 847, p. 163-178 16 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

Disrupting mitochondrial-nuclear coevolution affects OXPHOS complex i integrity and impacts human health

Gershoni, M., Levin, L., Ovadia, O., Toiw, Y., Shani, N., Dadon, S., Barzilai, N., Bergman, A., Atzmon, G., Wainstein, J., Tsur, A., Nijtmans, L., Glaser, B. & Mishmar, D., 2014, In : Genome Biology and Evolution. 6, 10, p. 2665-2680 16 p.

Research output: Contribution to journalArticle

44 Scopus citations

Epigenetics Decouples Mutational from Environmental Robustness. Did It Also Facilitate Multicellularity?

Gombar, S., MacCarthy, T. & Bergman, A., Mar 2014, In : PLoS Computational Biology. 10, 3, e1003450.

Research output: Contribution to journalArticle

4 Scopus citations

Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes

Vacic, V., Ozelius, L. J., Clark, L. N., Bar-Shira, A., Gana-Weisz, M., Gurevich, T., Gusev, A., Kedmi, M., Kenny, E. E., Liu, X., Mejia-Santana, H., Mirelman, A., Raymond, D., Saunders-Pullman, R., Desnick, R. J., Atzmon, G., Burns, E. R., Ostrer, H., Hakonarson, H., Bergman, A. & 10 others, Barzilai, N., Darvasi, A., Peter, I., Guha, S., Lencz, T., Giladi, N., Marder, K., Pe'er, I., Bressman, S. B. & Orr-Urtreger, A., Sep 2014, In : Human molecular genetics. 23, 17, p. 4693-4702 10 p., ddu158.

Research output: Contribution to journalArticle

23 Scopus citations

Identification of genes promoting skin youthfulness by genome-wide association study

Chang, A. L. S., Atzmon, G., Bergman, A., Brugmann, S., Atwood, S. X., Chang, H. Y. & Barzilai, N., Mar 2014, In : Journal of Investigative Dermatology. 134, 3, p. 651-657 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Invadopodia in context

Bergman, A., Condeelis, J. S. & Gligorijevic, B., May 1 2014, In : Cell Adhesion and Migration. 8, 3, p. 273-279 7 p.

Research output: Contribution to journalComment/debate

22 Scopus citations

Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion

Bruns, I., Lucas, D., Pinho, S., Ahmed, J., Lambert, M. P., Kunisaki, Y., Scheiermann, C., Schiff, L., Poncz, M., Bergman, A. & Frenette, P. S., Nov 1 2014, In : Nature Medicine. 20, 11, p. 1315-1320 6 p.

Research output: Contribution to journalArticle

262 Scopus citations

Multiparametric Classification Links Tumor Microenvironments with Tumor Cell Phenotype

Gligorijevic, B., Bergman, A. & Condeelis, J., 2014, In : PLoS biology. 12, 11

Research output: Contribution to journalArticle

79 Scopus citations

The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair

Van Oers, J. M. M., Edwards, Y., Chahwan, R., Zhang, W., Smith, C., Pechuan, X., Schaetzlein, S., Jin, B., Wang, Y., Bergman, A., Scharff, M. D. & Edelmann, W., Jul 24 2014, In : Oncogene. 33, 30, p. 3939-3946 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
2013

Arteriolar niches maintain haematopoietic stem cell quiescence

Kunisaki, Y., Bruns, I., Scheiermann, C., Ahmed, J., Pinho, S., Zhang, D., Mizoguchi, T., Wei, Q., Lucas, D., Ito, K., Mar, J. C., Bergman, A. & Frenette, P. S., Oct 10 2013, In : Nature. 502, 7473, p. 637-643 7 p.

Research output: Contribution to journalArticle

587 Scopus citations

CD169 + macrophages provide a niche promoting erythropoiesis under homeostasis and stress

Chow, A., Huggins, M., Ahmed, J., Hashimoto, D., Lucas, D., Kunisaki, Y., Pinho, S., Leboeuf, M., Noizat, C., Van Rooijen, N., Tanaka, M., Zhao, Z. J., Bergman, A., Merad, M. & Frenette, P. S., Apr 2013, In : Nature Medicine. 19, 4, p. 429-436 8 p.

Research output: Contribution to journalArticle

225 Scopus citations

Disease-enhancing antibodies improve the efficacy of bacterial toxin-neutralizing antibodies

Chow, S. K., Smith, C., Maccarthy, T., Pohl, M. A., Bergman, A. & Casadevall, A., Apr 17 2013, In : Cell Host and Microbe. 13, 4, p. 417-428 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Fungal virulence in a lepidopteran model is an emergent property with deterministic features

Garcia-Solache, M. A., Izquierdo-Garcia, D., Smith, C., Bergman, A. & Casadevall, A., 2013, In : mBio. 4, 3, e00100-13.

Research output: Contribution to journalArticle

22 Scopus citations

Old Cryptococcus neoformans cells contribute to virulence in chronic cryptococcosis

Bouklas, T., Pechuan, X., Goldman, D. L., Edelman, B., Bergman, A. & Friesa, B. C., Aug 13 2013, In : mBio. 4, 4, e00455-13.

Research output: Contribution to journalArticle

26 Scopus citations

Temporal behavior of capsule enlargement by Cryptococcus neoformans

Cordero, R. J. B., Bergman, A. & Casadevall, A., Oct 1 2013, In : Eukaryotic Cell. 12, 10, p. 1383-1388 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

The Underlying Molecular and Network Level Mechanisms in the Evolution of Robustness in Gene Regulatory Networks

Pujato, M., MacCarthy, T., Fiser, A. & Bergman, A., Jan 2013, In : PLoS Computational Biology. 9, 1, e1002865.

Research output: Contribution to journalArticle

13 Scopus citations
2012

A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation

Wontakal, S. N., Guo, X., Smith, C., MacCarthy, T., Bresnick, E. H., Bergman, A., Snyder, M. P., Weissman, S. M., Zheng, D. & Skoultchi, A. I., Mar 6 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 10, p. 3832-3837 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

A genome-wide scan of ashkenazi jewish crohn's disease suggests novel susceptibility loci

Kenny, E. E., Pe'er, I., Karban, A., Ozelius, L., Mitchell, A. A., Ng, S. M., Erazo, M., Ostrer, H., Abraham, C., Abreu, M. T., Atzmon, G., Barzilai, N., Brant, S. R., Bressman, S., Burns, E. R., Chowers, Y., Clark, L. N., Darvasi, A., Doheny, D., Duerr, R. H. & 23 others, Eliakim, R., Giladi, N., Gregersen, P. K., Hakonarson, H., Jones, M. R., Marder, K., McGovern, D. P. B., Mulle, J., Orr-Urtreger, A., Proctor, D. D., Pulver, A., Rotter, J. I., Silverberg, M. S., Ullman, T., Warren, S. T., Waterman, M., Zhang, W., Bergman, A., Mayer, L., Katz, S., Desnick, R. J., Cho, J. H. & Peter, I., Mar 2012, In : PLoS genetics. 8, 3, e1002559.

Research output: Contribution to journalArticle

95 Scopus citations
19 Scopus citations

Gene Size Matters

Mirina, A., Atzmon, G., Ye, K. & Bergman, A., Nov 9 2012, In : PloS one. 7, 11, e49093.

Research output: Contribution to journalArticle

13 Scopus citations
2011

A General Life History Theory for Effects of Caloric Restriction on Health Maintenance

Hou, C., Bolt, K. & Bergman, A., May 19 2011, In : BMC Systems Biology. 5, 78.

Research output: Contribution to journalArticle

8 Scopus citations

A general model for ontogenetic growth under food restriction

Hou, C., Bolt, K. M. & Bergman, A., Jan 1 2011, In : Proceedings of the Royal Society B: Biological Sciences. 278, 1720, p. 2881-2890 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Energetic basis of correlation between catch-up growth, health maintenance, and aging

Hou, C., Bolt, K. M. & Bergman, A., Jun 1 2011, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 66 A, 6, p. 627-638 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Recombinase-mediated cassette exchange as a novel method to study somatic hypermutation in ramos cells

Baughn, L. B., Kalis, S. L., MacCarthy, T., Wei, L., Fan, M., Bergman, A. & Scharff, M. D., 2011, In : mBio. 2, 5, e00186-11.

Research output: Contribution to journalArticle

6 Scopus citations
2010
45 Scopus citations

Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians

Atzmon, G., Cho, M., Cawthon, R. M., Budagov, T., Katz, M., Yang, X., Siegel, G., Bergman, A., Huffman, D. M., Schechter, C. B., Wright, W. E., Shay, J. W., Barzilai, N., Govindaraju, D. R. & Suh, Y., Jan 26 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, SUPPL. 1, p. 1710-1717 8 p.

Research output: Contribution to journalArticle

163 Scopus citations

Mammalian endothermy optimally restricts fungi and metabolic costs

Bergman, A. & Casadevall, A., Nov 2010, In : mBio. 1, 5, e00212-10.

Research output: Contribution to journalArticle

46 Scopus citations
2009

Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation

Abrajano, J. J., Qureshi, I. A., Gokhan, S., Zheng, D., Bergman, A. & Mehler, M. F., Nov 3 2009, In : PloS one. 4, 11, e7665.

Research output: Contribution to journalArticle

61 Scopus citations

REST and CoREST modulate neuronal subtype specification, maturation and maintenance

Abrajano, J. J., Qureshi, I. A., Gokhan, S., Zheng, D., Bergman, A. & Mehler, M. F., 2009, In : PloS one. 4, 12, e7936.

Research output: Contribution to journalArticle

87 Scopus citations

RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans

Sebastiani, P., Montano, M., Puca, A., Solovieff, N., Kojima, T., Wang, M. C., Melista, E., Meltzer, M., Fischer, S. E. J., Andersen, S., Hartley, S. H., Sedgewick, A., Arai, Y., Bergman, A., Barzilai, N., Terry, D. F., Riva, A., Anselmi, C. V., Malovini, A., Kitamoto, A. & 9 others, Sawabe, M., Arai, T., Gondo, Y., Steinberg, M. H., Hirose, N., Atzmon, G., Ruvkun, G., Baldwin, C. T. & Perls, T. T., 2009, In : PloS one. 4, 12, e8210.

Research output: Contribution to journalArticle

60 Scopus citations

SHMTool: A webserver for comparative analysis of somatic hypermutation datasets

MacCarthy, T., Roa, S., Scharff, M. D. & Bergman, A., Jan 1 2009, In : DNA Repair. 8, 1, p. 137-141 5 p.

Research output: Contribution to journalArticle

26 Scopus citations
26 Scopus citations

V-region mutation in vitro, in vivo, and in silico reveal the importance of the enzymatic properties of AID and the sequence environment

MacCarthy, T., Kalis, S. L., Roa, S., Pham, P., Goodman, M. F., Scharff, M. D. & Bergman, A., May 26 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 21, p. 8629-8634 6 p.

Research output: Contribution to journalArticle

29 Scopus citations
2008

Site-specific molecular signatures predict aggressive disease in hnscc

Belbin, T. J., Schlecht, N. F., Smith, R. V., Adrien, L. R., Kawachi, N., Brandwein-Gensler, M., Bergman, A., Chen, Q., Childs, G. & Prystowsky, M. B., 2008, In : Head and Neck Pathology. 2, 4, p. 243-256 14 p.

Research output: Contribution to journalArticle

22 Scopus citations