• 485 Citations
  • 13 h-Index
20082020

Research output per year

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Publications

  • 485 Citations
  • 13 h-Index
  • 17 Article
  • 1 Comment/debate
  • 1 Review article
2020

Hepatitis C Virus Infection of Human Thyrocytes: Metabolic, Hormonal, and Immunological Implications

Hammerstad, S. S., Blackard, J. T., Lombardi, A., Owen, R. P., Concepcion, E., Yi, Z., Zhang, W. & Tomer, Y., Apr 1 2020, In : The Journal of clinical endocrinology and metabolism. 105, 4

Research output: Contribution to journalArticle

2018

Interferon alpha: The key trigger of type 1 diabetes

Lombardi, A., Tsomos, E., Hammerstad, S. S. & Tomer, Y., Nov 2018, In : Journal of Autoimmunity. 94, p. 7-15 9 p.

Research output: Contribution to journalReview article

14 Scopus citations

Interferon-α triggers autoimmune thyroid diseases via lysosomal-dependent degradation of thyroglobulin

Faustino, L. C., Lombardi, A., Madrigal-Matute, J., Owen, R. P., Libutti, S. K. & Tomer, Y., Oct 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 10, p. 3678-3687 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

A preliminary analysis of hepatitis C virus in pancreatic islet cells

Blackard, J. T., Kong, L., Lombardi, A., Homann, D., Hammerstad, S. S. & Tomer, Y., Dec 20 2017, In : Virology Journal. 14, 1, 237.

Research output: Contribution to journalArticle

6 Scopus citations

CD40 signaling in graves disease is mediated through canonical and noncanonical thyroidal nuclear factor kB activation

Lee, H. J., Lombardi, A., Stefan, M., Li, C. W., Inabnet, W. B., Owen, R. P., Concepcion, E. & Tomer, Y., Feb 1 2017, In : Endocrinology. 158, 2, p. 410-418 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Impaired mitochondrial calcium uptake caused by tacrolimus underlies beta-cell failure

Lombardi, A., Trimarco, B., Iaccarino, G. & Santulli, G., Nov 13 2017, In : Cell Communication and Signaling. 15, 1, 47.

Research output: Contribution to journalArticle

20 Scopus citations

Sirolimus induces depletion of intracellular calcium stores and mitochondrial dysfunction in pancreatic beta cells

Lombardi, A., Gambardella, J., Du, X. L., Sorriento, D., Mauro, M., Iaccarino, G., Trimarco, B. & Santulli, G., Jan 1 2017, In : Scientific reports. 7, 15823.

Research output: Contribution to journalArticle

12 Scopus citations
2016

Dissecting the genetic susceptibility to graves' disease in a cohort of patients of Italian origin

Lombardi, A., Menconi, F., Greenberg, D., Concepcion, E., Leo, M., Rocchi, R., Marinó, M., Keddache, M. & Tomer, Y., Mar 8 2016, In : Frontiers in Endocrinology. 7, MAR, 21.

Research output: Contribution to journalArticle

21 Scopus citations

Interferon alpha impairs insulin production in human beta cells via endoplasmic reticulum stress

Lombardi, A. & Tomer, Y., Nov 12 2016, (Accepted/In press) In : Journal of Autoimmunity.

Research output: Contribution to journalArticle

21 Scopus citations
2015

Endoplasmic reticulum stress as a novel mechanism in amiodaroneinduced destructive thyroiditis

Lombardi, A., Inabnet, W. B., Owen, R., Farenholtz, K. E. & Tomer, Y., Jan 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 1, p. E1-E10

Research output: Contribution to journalArticle

Open Access
19 Scopus citations
2014

Genetic analysis in young-age-of-onset graves' disease reveals new susceptibility loci

Brown, R. S., Lombardi, A., Hasham, A., Greenberg, D. A., Gordon, J., Concepcion, E., Hammerstad, S. S., Lotay, V., Zhang, W. & Tomer, Y., Jul 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 7, p. E1387-E1391

Research output: Contribution to journalArticle

19 Scopus citations

Genetic-epigenetic dysregulation of thymic TSH receptor gene expression triggers thyroid autoimmunity

Stefan, M., Wei, C., Lombardi, A., Li, C. W., Concepcion, E. S., Inabnet, W. B., Owen, R., Zhang, W. & Tomer, Y., Aug 26 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 34, p. 12562-12567 6 p.

Research output: Contribution to journalArticle

53 Scopus citations
2012

Age-related impairment in insulin release: The essential role of β 2-adrenergic receptor

Santulli, G., Lombardi, A., Sorriento, D., Anastasio, A., Del Giudice, C., Formisano, P., Béguinot, F., Trimarco, B., Miele, C. & Iaccarino, G., Mar 1 2012, In : Diabetes. 61, 3, p. 692-701 10 p.

Research output: Contribution to journalArticle

67 Scopus citations

Erratum: Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E (Diabetologia DOI: 10.1007/s00125-011-2280-8)

Fiory, F., Lombardi, A., Miele, C., Giudicelli, J., Beguinot, F. & Van Obberghen, E., Jan 2012, In : Diabetologia. 55, 1, 1 p.

Research output: Contribution to journalComment/debate

Increased hexosamine biosynthetic pathway flux dedifferentiates INS-1E cells and murine islets by an extracellular signal-regulated kinase (ERK)1/2-mediated signal transmission pathway

Lombardi, A., Ulianich, L., Treglia, A. S., Nigro, C., Parrillo, L., Lofrumento, D. D., Nicolardi, G., Garbi, C., Beguinot, F., Miele, C. & Di Jeso, B., Jan 1 2012, In : Diabetologia. 55, 1, p. 141-153 13 p.

Research output: Contribution to journalArticle

23 Scopus citations
2011

Cardiac resynchronisation therapy response predicts occurrence of atrial fibrillation in non-ischaemic dilated cardiomyopathy

D'Ascia, S. L., D'Ascia, C., Marino, V., Lombardi, A., Santulli, R., Chiariello, M. & Santulli, G., Nov 1 2011, In : International Journal of Clinical Practice. 65, 11, p. 1149-1155 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E

Fiory, F., Lombardi, A., Miele, C., Giudicelli, J., Beguinot, F. & Van Obberghen, E., Nov 2011, In : Diabetologia. 54, 11, p. 2941-2952 12 p.

Research output: Contribution to journalArticle

65 Scopus citations

Tyr phosphatase-mediated P-ERK inhibition suppresses senescence in EIA + v-raf transformed cells, which, paradoxically, are apoptosis-protected in a MEK-dependent manner

de Vitis, S., Treglia, A. S., Ulianich, L., Turco, S., Terrazzano, G., Lombardi, A., Miele, C., Garbi, C., Beguinot, F. & di Jeso, B., Feb 2011, In : Neoplasia. 13, 2, p. 120-130 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2008

In skeletal muscle advanced glycation end products (AGEs) inhibit insulin action and induce the formation of multimolecular complexes including the receptor for AGEs

Cassese, A., Esposito, I., Fiory, F., Barbagallo, A. P. M., Paturzo, F., Mirra, P., Ulianich, L., Giacco, F., Iadicicco, C., Lombardi, A., Oriente, F., Van Obberghen, E., Beguinot, F., Formisano, P. & Miele, C., Dec 26 2008, In : Journal of Biological Chemistry. 283, 52, p. 36088-36099 12 p.

Research output: Contribution to journalArticle

79 Scopus citations