Systems & Computational Biology

Fingerprint Dive into the research topics where Systems & Computational Biology is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Proteins Medicine & Life Sciences
Proton-Coupled Folate Transporter Medicine & Life Sciences
Genes Chemical Compounds
Mutation Medicine & Life Sciences
Folic Acid Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
Gene Regulatory Networks Medicine & Life Sciences
Gene expression Chemical Compounds

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Profiles

No photo of Aviv Bergman

Aviv Bergman, Ph.D.

Person: Academic

19872019
No photo of Ruben Coen Cagli

Ruben Coen Cagli, Ph.D.

Person: Academic

20052017
No photo of Jorge E. Fajardo

Jorge E. Fajardo, Ph.D.

Person: Academic

19902019

Projects 2007 2023

Interdisciplinary protein engineering approach to design high affinity antibodies for flaviviruses

Fiser, A.

National Institutes of Health

11/15/18 → 10/31/23

Project: Research project

Protein Engineering
Flavivirus
Antibody Affinity
Bacteriophages
Libraries

Computational models for the signaling of tumor necrosis factor receptor on cell surfaces

Wu, Y.

National Institutes of Health

9/20/17 → 7/31/21

Project: Research project

Tumor Necrosis Factor Receptors
Ligands
Tumor Necrosis Factor-alpha
Cell Surface Receptors
Cytokines

A multiscale model for binding kinetics of membrane receptors on cell surfaces

Wu, Y.

National Institutes of Health

9/1/16 → 7/31/21

Project: Research project

Cell Surface Receptors
Ligands
Membranes
Costimulatory and Inhibitory T-Cell Receptors
Pharmaceutical Preparations

Research Output 2003 2019

Bringing microbiome-drug interaction research into the clinic

Guthrie, L. & Kelly, L., Jan 1 2019, In : EBioMedicine.

Research output: Contribution to journal › Review article

Open Access
Drug interactions
Microbiota
Drug Interactions
Research
Pharmaceutical Preparations

CCL2 mobilizes ALIX to facilitate Gag-p6 mediated HIV-1 virion release

Ajasin, D. O., Rao, V. R., Wu, X., Ramasamy, S., Pujato, M., Ruiz, A. P., Fiser, A., Bresnick, A. R., Kalpana, G. V. & Prasad, V. R., Jun 7 2019, In : eLife. 8

Research output: Contribution to journal › Article

Open Access
Viruses
Virion
HIV-1
Endosomal Sorting Complexes Required for Transport
Actins

Computational Redesign of PD-1 Interface for PD-L1 Ligand Selectivity

Shrestha, R., Garrett, S. C., Almo, S. C. & Fiser, A., May 7 2019, In : Structure. 27, 5, p. 829-836.e3

Research output: Contribution to journal › Article

Cell Death
Ligands
Programmed Cell Death 1 Receptor
T-Lymphocytes
Human Engineering