Medicine

Projects

Projects per year 1975 1989 2002 2003 2005 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2025

• 25 Not started
• 81 Active
• 974 Finished

Projects per year

Search results

• Finished

  Emergence of bedaquiline and clofazimine resistance after interruption of drug-resistant TB therapy in a high HIV prevalence setting

  Brust, J. C. M. & Brust, J. C. M.

  National Institute of Allergy and Infectious Diseases

  12/26/19 → 11/30/22

  Project: Research project

  • bedaquiline 100%
  • Clofazimine 74%
  • Multidrug-Resistant Tuberculosis 36%
  • HIV 34%
  • Extensively Drug-Resistant Tuberculosis 32%

• Molecular regulation of gut lipid metabolism by mTOR and autophagy proteins

  Singh, R.

  9/17/19 → 8/31/21

  Project: Research project

  • Triglycerides 100%
  • Autophagy 83%
  • Endoplasmic Reticulum 53%
  • Metabolic Syndrome 34%
  • Enterocytes 29%

• Circadian Mechanisms of Diabetes Prevention in Aged mice

  Singh, R.

  9/15/19 → 5/31/22

  Project: Research project

  • Autophagy 100%
  • Gluconeogenesis 68%
  • Caloric Restriction 47%
  • Type 2 Diabetes Mellitus 28%
  • lysosomal proteins 27%

• Treat All and beyond: addressing methods, data and capacity building challenges in the African regions of IeDEA

  Anastos, K. & Davies, M. A.

  National Institute of Allergy and Infectious Diseases

  8/1/19 → 7/31/20

  Project: Research project

  • Capacity Building 100%
  • Africa South of the Sahara 30%
  • Research Personnel 28%
  • National Institute of Allergy and Infectious Diseases (U.S.) 21%
  • Rwanda 19%

• Treat All and beyond: addressing methods, data and capacity building challenges in the African regions of IeDEA

  Anastos, K.

  8/1/19 → 7/31/20

  Project: Research project

  • Capacity Building 100%
  • Africa South of the Sahara 82%
  • Research Personnel 78%
  • National Institute of Allergy and Infectious Diseases (U.S.) 57%
  • Rwanda 54%

• Antibodies, B cells and resistance to human cryptococcosis

  Pirofski, L.

  7/25/19 → 6/30/22

  Project: Research project

  • Cryptococcal Meningitis 100%
  • Immune Reconstitution Inflammatory Syndrome 41%
  • Glucans 31%
  • HIV 26%
  • B-Lymphocytes 14%

• Impact of multiple stigmas on HIV care continuum outcomes for key populations

  Patel, V. V.

  7/17/19 → 6/30/21

  Project: Research project

  • HIV 100%
  • India 39%
  • Retention in Care 33%
  • Continuity of Patient Care 25%
  • Mental Health 17%

• Impact of multiple stigmas on HIV care continuum outcomes for key populations

  Patel, V. V.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  7/17/19 → 6/30/21

  Project: Research project

  • Continuity of Patient Care 100%
  • HIV 82%
  • Population 34%
  • India 34%
  • Retention in Care 28%

• Functional role of IP3 receptors in the regulation of cardiac myofibroblasts

  Santulli, G.

  7/1/19 → 6/30/21

  Project: Research project

  • Fibroblasts 100%
  • Fibrosis 77%
  • Myocardial Infarction 43%
  • Inositol 1,4,5-Trisphosphate Receptors 39%
  • Autophagy 28%

• Characteristics and protective efficacy of human antibodies against M. tuberculosis

  Achkar, J. M.

  7/1/19 → 6/30/22

  Project: Research project

  • Tuberculosis 100%
  • Mycobacterium tuberculosis 71%
  • Polysaccharides 45%
  • Tuberculosis Vaccines 34%
  • Epitopes 20%

• Cancer Center Administration

  Seither, R.

  National Cancer Institute

  7/1/19 → 6/30/22

  Project: Research project

  • cancer 100%
  • management 26%
  • leadership 21%
  • monitoring 16%
  • administrative services 15%

• Cancer Biospecimen Acquisition & Biorepository

  Stein, D. D. T. & Stein, D. T.

  National Cancer Institute

  7/1/19 → 6/30/22

  Project: Research project

  • neoplasms 100%
  • tissues 45%
  • sampling 16%
  • health information 14%
  • medical records 13%

• Clinical Protocol & Data Management (CPDM)

  Sparano, J. J. A. & Sparano, J. A.

  National Cancer Institute

  7/1/19 → 6/30/22

  Project: Research project

  • Data Management 100%
  • Clinical Protocols 74%
  • Early Detection of Cancer 20%
  • Neoplasms 17%
  • Clinical Trials Data Monitoring Committees 16%

• Protocol Review & Monitoring System (PRMS)

  Goel, S. S. & Goel, S.

  National Cancer Institute

  7/1/19 → 6/30/22

  Project: Research project

  • protocols 100%
  • monitoring 88%
  • committees 57%
  • peers 17%
  • neoplasms 15%

• Plasmodium phospholipase A2s as potential novel drug targets

  Daily, J. P.

  6/21/19 → 5/31/21

  Project: Research project

  • Cerebral Malaria 100%
  • Brain Edema 80%
  • Endothelial Cells 53%
  • Permeability 52%
  • Plasmodium falciparum 51%

• Plasmodium phospholipase A2s as potential novel drug targets

  Daily, J. P.

  National Institute of Allergy and Infectious Diseases

  6/21/19 → 5/31/20

  Project: Research project

  • Cerebral Malaria 100%
  • Brain Edema 80%
  • Endothelial Cells 53%
  • Permeability 52%
  • Phospholipases 51%

• Somatotropic Signaling and Resilience to Aging and Alzheimer's Disease

  Milman, S.

  4/15/19 → 1/31/22

  Project: Research project

  • Alzheimer Disease 100%
  • Aged, 80 and over 58%
  • Exome 38%
  • Autophagy 30%
  • Dementia 26%

• Somatotropic Signaling and Resilience to Aging and Alzheimer's Disease

  Milman, S. & Milman, S.

  National Institute on Aging

  4/15/19 → 1/31/23

  Project: Research project

  • Alzheimer Disease 100%
  • Aged, 80 and over 36%
  • Dementia 24%
  • Pandemics 22%
  • Exome 22%

• Vulnerability of SCLC based on bi-allelic genetic inactivation of RB1 and TP53

  Zhao, H. & Schwartz, E. L.

  4/12/19 → 3/31/22

  Project: Research project

  • Small Cell Lung Carcinoma 100%
  • Drug Therapy 17%
  • Heterografts 16%
  • Ubiquitination 13%
  • Neoplasms 11%

• Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS)

  Sharma, A. & Anastos, K.

  4/1/19 → 3/31/21

  Project: Research project

  • HIV 100%
  • Cardiovascular Diseases 29%
  • Cohort Studies 27%
  • Comorbidity 18%
  • Microbiota 15%

• IgM in the regulation of TB immunity

  Chan, J.

  2/15/19 → 1/31/22

  Project: Research project

  • Mycobacterium tuberculosis 100%
  • Immunoglobulin M 98%
  • Germinal Center 74%
  • Humoral Immunity 24%
  • B-Lymphocytes 24%

• IgM in the regulation of TB immunity

  Chan, J. & Chan, J. J. R.

  National Institute of Allergy and Infectious Diseases

  2/15/19 → 1/31/23

  Project: Research project

  • Immunoglobulin M 100%
  • Mycobacterium tuberculosis 96%
  • Immunity 80%
  • Germinal Center 61%
  • Humoral Immunity 20%

• Hemolysis and Platelet Activation during Continuous Flow Mechanical Circulatory Support

  Saeed, O.

  1/15/19 → 12/31/21

  Project: Research project

  • Hemolysis 100%
  • Platelet Activation 64%
  • Platelet Aggregation 52%
  • Thrombosis 34%
  • Sildenafil Citrate 27%

• Cooperative Research Agreements Related to the World Trade Center Health Program (U01)

  Verma, A. K.

  1/1/19 → 6/30/20

  Project: Research project

• Integrative, age-related changes in genome and epigenome in human lung in relation to smoking

  Vijg, J. & Spivack, S. D.

  1/1/19 → 12/31/21

  Project: Research project

  • DNA Damage 100%
  • Genomic Instability 75%
  • Lung Diseases 61%
  • Lung 61%
  • Epigenomics 60%

• Developmental PBDE exposure, gut microbiome, and diabetes

  Mani, S.

  1/1/19 → 12/31/21

  Project: Research project

  • Halogenated Diphenyl Ethers 100%
  • Gastrointestinal Microbiome 55%
  • Dysbiosis 35%
  • Indoles 30%
  • Tryptophan 30%

• Mechanisms of cardiovascular disease

  Kitsis, R. N. & Sibinga, N. E. S.

  1/1/19 → 12/31/21

  Project: Research project

  • Cardiovascular Diseases 100%
  • Molecular Biology 74%
  • Cardiologists 51%
  • Vascular Diseases 44%
  • Myocardial Ischemia 40%

• Mechanisms of cardiovascular disease

  Kitsis, R. R. N., Kitsis, R. N., Sibinga, N. E. S. & Sibinga, N. E. S.

  National Heart, Lung, and Blood Institute

  1/1/19 → 12/31/22

  Project: Research project

  • Cardiovascular Diseases 100%
  • Molecular Biology 26%
  • Research Personnel 22%
  • Cardiologists 18%
  • Vascular Diseases 16%

• Integrative, age-related changes in genome and epigenome in human lung in relation to smoking

  Spivack, S. D., Vijg, J., Spivack, S. D. & Vijg, J.

  National Heart, Lung, and Blood Institute

  1/1/19 → 12/31/22

  Project: Research project

  • Epigenome 100%
  • Smoking 62%
  • Genome 54%
  • Lung Diseases 51%
  • Lung 49%

• Developmental PBDE exposure, gut microbiome, and diabetes

  Cui, Y. Y., CUI, Y., Gu, H., Gu, H. H., Mani, S. & Mani, S. S.

  National Institute of Environmental Health Sciences

  1/1/19 → 12/31/22

  Project: Research project

  • Halogenated Diphenyl Ethers 100%
  • Gastrointestinal Microbiome 58%
  • Dysbiosis 27%
  • Indoles 15%
  • Tryptophan 15%

• Modifies of PrEP Efficacy in US & African Women: Age, Hormones, Sex & Microbiota

  Keller, M. J.

  National Institute of Allergy and Infectious Diseases

  1/1/19 → 12/31/19

  Project: Research project

• Social Dancing Intervention for older adults at high risk of Alzheimer's disease and other dementias: A pilot study

  Verghese, J., Blumen, H. M. & Verghese, J.

  National Institute on Aging

  9/15/18 → 8/31/21

  Project: Research project

  • Dementia 100%
  • Executive Function 80%
  • Alzheimer Disease 71%
  • Neuronal Plasticity 37%
  • Cognitive Dysfunction 31%

• Social Dancing Intervention for older adults at high risk of Alzheimer's disease and other dementias: A pilot study

  Blumen, H. M., Verghese, J. & Verghese, J.

  9/15/18 → 8/31/21

  Project: Research project

  • Dementia 100%
  • Executive Function 74%
  • Neuronal Plasticity 34%
  • Cognitive Dysfunction 29%
  • Walking 20%

• Peer mentorship to improve outcomes in patients on maintenance hemodialysis

  Melamed, M. L., Golestaneh, L., Golestaneh, L. & Melamed, M. L.

  9/6/18 → 7/31/21

  Project: Research project

  • Mentors 100%
  • Dialysis 59%
  • Self-Management 43%
  • Renal Dialysis 34%
  • Hospitalization 29%

• Peer mentorship to improve outcomes in patients on maintenance hemodialysis

  Golestaneh, L., Cavanaugh, K., Melamed, M. L. & Golestaneh, L.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/6/18 → 7/31/21

  Project: Research project

  • Mentors 100%
  • Renal Dialysis 64%
  • Maintenance 49%
  • Dialysis 45%
  • Self-Management 33%

• Optimizing smoking cessation interventions for PLWH in Nairobi, Kenya

  Shuter, J. & Shuter, J.

  9/5/18 → 8/31/21

  Project: Research project

  • Acquired Immunodeficiency Syndrome 100%
  • HIV 82%
  • Methadone 76%
  • Smoke 63%
  • Smoking Cessation 53%

• TREAT ECARDS: Translating Evidence into Action: Electronic Clinical Decision Support in ARDS

  Gong, M. N.

  9/1/18 → 6/30/21

  Project: Research project

  • Adult Respiratory Distress Syndrome 100%
  • Clinical Decision Support Systems 28%
  • Practice Guidelines 12%
  • Professional Practice 10%
  • Workflow 9%

• Identification and targeting of pathways separating healthy stem cell aging from malignant transformation

  Will, B.

  9/1/18 → 8/31/21

  Project: Research project

  • Chaperone-Mediated Autophagy 100%
  • Stem Cells 33%
  • Hematopoietic Stem Cells 24%
  • Genetic Models 11%
  • Neoplastic Stem Cells 10%

• Identifying and Reducing Disparities in Outcomes Among Economically Vulnerable and Minority Young Adults with Type 1 Diabetes

  Agarwal, S.

  9/1/18 → 8/31/21

  Project: Research project

  • Type 1 Diabetes Mellitus 100%
  • Young Adult 90%

• Therapeutic targeting of MDS stem cells

  Steidl, U. G. & Verma, A. K.

  8/20/18 → 6/30/22

  Project: Research project

  • Interleukin-8 100%
  • Stem Cells 42%
  • Heterografts 17%
  • Disease Progression 15%
  • Interleukin-8 Receptors 14%

• Assessing genome sequence integrity in normal human cells

  Spivack, S. D., Vijg, J. & Vijg, J.

  8/15/18 → 5/31/22

  Project: Research project

  • Mutation 100%
  • Genome 74%
  • Smoke 52%
  • Tobacco 52%
  • DNA 45%

• Digital Implementation Intervention Trials in Acute Lung Care (DIGITAL-C) Network Planning

  Gong, M. N.

  8/15/18 → 10/31/20

  Project: Research project

  • Respiratory Insufficiency 100%
  • Evidence-Based Practice 79%
  • Practice Guidelines 66%
  • Adult Respiratory Distress Syndrome 64%
  • Artificial Respiration 44%

• Digital Implementation Intervention Trials in Acute Lung Care (DIGITAL-C) Network Planning

  SALES, A. E. & Gong, M. N.

  National Heart, Lung, and Blood Institute

  8/15/18 → 10/31/20

  Project: Research project

  • Respiratory Insufficiency 100%
  • Evidence-Based Practice 79%
  • Practice Guidelines 66%
  • Adult Respiratory Distress Syndrome 64%
  • Artificial Respiration 44%

• Microbial Metabolite Mimics, PXR and Colitis-Induced Colorectal Cancer

  Mani, S.

  8/14/18 → 7/31/21

  Project: Research project

  • Pregnane 100%
  • Indole 22%
  • Metabolite 8%
  • Non Toxic 8%

• Microbial Metabolite Mimics, PXR and Colitis-Induced Colorectal Cancer

  Mani, S.

  8/14/18 → 7/31/22

  Project: Research project

  • Pregnane 100%
  • Indole 22%
  • Metabolite 8%
  • Non Toxic 8%

• Mapping the Developing Beige Fat by Massively Parallel Single Cell Analysis

  Shinoda, K. & Shinoda, K.

  National Institute of Diabetes and Digestive and Kidney Diseases

  8/6/18 → 7/31/21

  Project: Research project

  • Beige Adipose Tissue 100%
  • Single-Cell Analysis 77%
  • White Adipose Tissue 74%
  • Beige Adipocytes 71%
  • Brown Adipose Tissue 53%

• Calcification Propensity, using Dynamic Light Scattering, to Study Vascular Calcification in Patients with Advanced Chronic Kidney Disease

  Chen, W.

  8/1/18 → 5/31/22

  Project: Research project

  • Vascular Calcification 100%
  • Chronic Renal Insufficiency 27%
  • Dynamic Light Scattering 15%
  • Osteocalcin 12%
  • Biomarkers 11%

• Surfactant-vesicle based gonorrhea vaccine

  Stein, D. T.

  8/1/18 → 7/31/20

  Project: Research project

  • Vaccines 100%
  • Neisseria gonorrhoeae 45%
  • Gonorrhea 45%
  • Smallpox 26%
  • Poliomyelitis 22%

• Adapting, Scaling, and Spreading an Algorithmic Asthma Mobile Intervention to Promote Patient-Reported Outcomes Within Primary Care Settings

  Jariwala, S. P.

  8/1/18 → 5/31/21

  Project: Research project

  • Primary Health Care 100%
  • Asthma 98%
  • Patient Reported Outcome Measures 64%
  • Patient Education 30%
  • Education 18%

• Apolipoprotein A5 and Gallstone Formation

  Wang, D. Q. H.

  7/20/18 → 4/30/22

  Project: Research project

  • apolipoproteins 100%
  • bile 58%
  • cholelithiasis 55%
  • cholesterol 30%
  • liver 26%