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Germline deletion of Igh 3′ regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus

Volpi, S. A., Verma-Gaur, J., Hassan, R., Ju, Z., Roa, S., Chatterjee, S., Werling, U., Hou, H., Will, B., Steidl, U., Scharff, M., Edelman, W., Feeney, A. J. & Birshtein, B. K., Mar 15 2012, In : Journal of Immunology. 188, 6, p. 2556-2566 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Germline NPM1 mutations lead to altered rRNA 2′-O-methylation and cause dyskeratosis congenita

Nachmani, D., Bothmer, A. H., Grisendi, S., Mele, A., Bothmer, D., Lee, J. D., Monteleone, E., Cheng, K., Zhang, Y., Bester, A. C., Guzzetti, A., Mitchell, C. A., Mendez, L. M., Pozdnyakova, O., Sportoletti, P., Martelli, M. P., Vulliamy, T. J., Safra, M., Schwartz, S., Luzzatto, L. & 8 others, Bluteau, O., Soulier, J., Darnell, R. B., Falini, B., Dokal, I., Ito, K., Clohessy, J. G. & Pandolfi, P. P., Oct 1 2019, In : Nature Genetics. 51, 10, p. 1518-1529 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination

Liedtke, W., Edelmann, W., Bieri, P. L., Chiu, F. C., Cowan, N. J., Kucherlapati, R. & Raine, C. S., Oct 1996, In : Neuron. 17, 4, p. 607-615 9 p.

Research output: Contribution to journalArticle

367 Scopus citations

Global chromatin compaction limits the strength of the DNA damage response

Murga, M., Jaco, I., Fan, Y., Soria, R., Martinez-Pastor, B., Cuadrado, M., Yang, S. M., Blasco, M. A., Skoultchi, A. I. & Fernandez-Capetillo, O., Sep 24 2007, In : Journal of Cell Biology. 178, 7, p. 1101-1108 8 p.

Research output: Contribution to journalArticle

171 Scopus citations

Globin switches in yolk sac-like primitive and fetal-like definitive red blood cells produced from human embryonic stem cells

Qiu, C., Olivier, E. N., Velho, M. & Bouhassira, E. E., Feb 15 2008, In : Blood. 111, 4, p. 2400-2408 9 p.

Research output: Contribution to journalArticle

117 Scopus citations

Glycobiology: a new dimension in diversity

Stanley, P., Mar 1989, In : Trends in Biotechnology. 7, 3, p. 47-49 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity

North, S. J., Huang, H. H., Sundaram, S., Jang-Lee, J., Etienne, A. T., Trollope, A., Chalabi, S., Dell, A., Stanley, P. & Haslam, S. M., Feb 19 2010, In : Journal of Biological Chemistry. 285, 8, p. 5759-5775 17 p.

Research output: Contribution to journalArticle

133 Scopus citations

Glycoprotein D actively induces rapid internalization of two nectin-1 isoforms during herpes simplex virus entry

Stiles, K. M. & Krummenacher, C., Mar 30 2010, In : Virology. 399, 1, p. 109-119 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Glycosylation mutants and the functions of mammalian carbohydrates

Stanley, P., 1987, In : Trends in Genetics. 3, C, p. 77-81 5 p.

Research output: Contribution to journalArticle

52 Scopus citations

GnT1IP-L specifically inhibits MGAT1 in the Golgi via its luminal domain

Huang, H. H., Hassinen, A., Sundaram, S., Spiess, A. N., Kellokumpu, S. & Stanley, P., Sep 15 2015, In : eLife. 4, September2015, e08916.

Research output: Contribution to journalArticle

9 Scopus citations

Golgi glycosylation

Stanley, P., Apr 1 2011, In : Cold Spring Harbor Perspectives in Biology. 3, 4, p. 1-13 13 p.

Research output: Contribution to journalArticle

151 Scopus citations

Goosecoid-like (Gscl), a candidate gene for velocardiofacial syndrome, is not essential for normal mouse development

Saint-Jore, B., Puech, A., Heyer, J., Lin, Q., Raine, C., Kucherlapati, R. & Skoultchi, A. I., Nov 1 1998, In : Human molecular genetics. 7, 12, p. 1841-1849 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

G-quadruplex-interacting compounds alter latent DNA replication and episomal persistence of KSHV

Madireddy, A., Purushothaman, P., Loosbroock, C. P., Robertson, E. S., Schildkraut, C. L. & Verma, S. C., May 5 2016, In : Nucleic acids research. 44, 8, p. 3675-3694 20 p.

Research output: Contribution to journalArticle

31 Scopus citations

Growth and muscle defects in mice lacking adult myosin heavy chain genes

Acakpo-Satchivi, L. J. R., Edelmann, W., Sartorius, C., Lu, B. D., Wahr, P. A., Watkins, S. C., Metzger, J. M., Leinwand, L. & Kucherlapati, R., Dec 1 1997, In : Journal of Cell Biology. 139, 5, p. 1219-1229 11 p.

Research output: Contribution to journalArticle

64 Scopus citations

Growth and stability of a cholesterol-independent Semliki Forest virus mutant in mosquitoes

Ahn, A., Schoepp, R. J., Sternberg, D. & Kielian, M., Sep 30 1999, In : Virology. 262, 2, p. 452-456 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Growth-dependent expression of a cell surface glycoprotein

Theilmann, L., Teicher, L., Schildkraut, C. S. & Stockert, R. J., Jun 2 1983, In : BBA - Molecular Cell Research. 762, 3, p. 475-477 3 p.

Research output: Contribution to journalArticle

16 Scopus citations

Gut microbial metabolism drives transformation of msh2-deficient colon epithelial cells

Belcheva, A., Irrazabal, T., Robertson, S. J., Streutker, C., Maughan, H., Rubino, S., Moriyama, E. H., Copeland, J. K., Kumar, S., Green, B., Geddes, K., Pezo, R. C., Navarre, W. W., Milosevic, M., Wilson, B. C., Girardin, S. E., Wolever, T. M. S., Edelmann, W., Guttman, D. S., Philpott, D. J. & 1 others, Martin, A., Jul 17 2014, In : Cell. 158, 2, p. 288-299 12 p.

Research output: Contribution to journalArticle

199 Scopus citations

H1° histone and differentiation of dendritic cells. A molecular target for tumor-derived factors

Gabrilovich, D. I., Cheng, P., Fan, Y., Yu, B., Nikitina, E., Sirotkin, A., Shurin, M., Oyama, T., Adachi, Y., Nadaf, S., Carbone, D. P. & Skoultchi, A. I., Aug 1 2002, In : Journal of Leukocyte Biology. 72, 2, p. 285-296 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

H1 linker histone promotes epigenetic silencing by regulating both DNA methylation and histone H3 methylation

Yang, S. M., Kim, B. J., Toro, L. N. & Skoultchi, A. I., Jan 29 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 5, p. 1708-1713 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

H1 linker histones are essential for mouse development and affect nucleosome spacing in vivo

Fan, Y., Nikitina, T., Morin-Kensicki, E. M., Zhao, J., Magnuson, T. R., Woodcock, C. L. & Skoultchi, A. I., Jul 1 2003, In : Molecular and cellular biology. 23, 13, p. 4559-4572 14 p.

Research output: Contribution to journalArticle

203 Scopus citations

H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction

Healton, S. E., Pinto, H. D., Mishra, L. N., Hamilton, G. A., Hamilton, G. A., Wheat, J. C., Swist-Rosowska, K., Shukeir, N., Dou, Y., Steidl, U., Jenuwein, T., Gamble, M. J., Gamble, M. J. & Skoultchi, A. I., Jun 23 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 25, p. 14251-14258 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

H2.0-like Homeobox Regulates Early Hematopoiesis and Promotes Acute Myeloid Leukemia

Kawahara, M., Pandolfi, A., Bartholdy, B., Barreyro, L., Will, B., Roth, M., Okoye-Okafor, U. C., Todorova, T. I., Figueroa, M. E., Melnick, A., Mitsiades, C. S. & Steidl, U., Aug 14 2012, In : Cancer Cell. 22, 2, p. 194-208 15 p.

Research output: Contribution to journalArticle

33 Scopus citations
45 Scopus citations

Haploid genetic screen reveals a profound and direct dependence on cholesterol for hantavirus membrane fusion

Kleinfelter, L. M., Jangra, R. K., Jae, L. T., Herbert, A. S., Mittler, E., Stiles, K. M., Wirchnianski, A. S., Kielian, M., Brummelkamp, T. R., Dye, J. M. & Chandran, K., Jun 30 2015, In : mBio. 6, 4, e00801-15.

Research output: Contribution to journalArticle

48 Scopus citations

Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression

Kucherlapati, M., Yang, K., Kuraguchi, M., Zhao, J., Lia, M., Heyer, J., Kane, M. F., Fan, K., Russell, R., Brown, A. M. C., Kneitz, B., Edelmann, W., Kolodner, R. D., Lipkin, M. & Kucherlapati, R., Jul 23 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 15, p. 9924-9929 6 p.

Research output: Contribution to journalArticle

198 Scopus citations

Heavy chain producing variants of a mouse myeloma cell line

Morrison, S. L. & Scharff, M. D., Dec 1 1975, In : Journal of Immunology. 114, 2 I, p. 655-659 5 p.

Research output: Contribution to journalArticle

61 Scopus citations

Hematopoietic stem cell fate through metabolic control

Ito, K. & Ito, K., Aug 2018, In : Experimental Hematology. 64, p. 1-11 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Hemoglobin C in transgenic mice: Effect of HbC expression from founders to full mouse globin knockouts

Fabry, M. E., Romero, J. R., Suzuka, S. M., Gilman, J. G., Feeling-Taylor, A., Odunusi, E., Factor, S. M., Bouhassira, E. E., Lawrence, C. & Nagel, R. L., 2000, In : Blood Cells, Molecules, and Diseases. 26, 4, p. 331-347 17 p.

Research output: Contribution to journalArticle

14 Scopus citations

Herpes simplex virus glycoprotein D interferes with binding of herpesvirus entry mediator to its ligands through downregulation and direct competition

Stiles, K. M., Whitbeck, J. C., Lou, H., Cohen, G. H., Eisenberg, R. J. & Krummenacher, C., Nov 2010, In : Journal of virology. 84, 22, p. 11646-11660 15 p.

Research output: Contribution to journalArticle

42 Scopus citations

HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function

Zhao, R., Chinai, J. M., Buhl, S., Scandiuzzi, L., Ray, A., Jeon, H., Ohaegbulam, K. C., Ghosh, K., Zhao, A., Scharff, M. D. & Zang, X., Jun 11 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 24, p. 9879-9884 6 p.

Research output: Contribution to journalArticle

68 Scopus citations

Hierarchical Modularity and the Evolution of Genetic Interactomes across Species

Ryan, C. J., Roguev, A., Patrick, K., Xu, J., Jahari, H., Tong, Z., Beltrao, P., Shales, M., Qu, H., Collins, S. R., Kliegman, J. I., Jiang, L., Kuo, D., Tosti, E., Kim, H. S., Edelmann, W., Keogh, M. C., Greene, D., Tang, C., Cunningham, P. & 7 others, Shokat, K. M., Cagney, G., Svensson, J. P., Guthrie, C., Espenshade, P. J., Ideker, T. & Krogan, N. J., Jun 8 2012, In : Molecular Cell. 46, 5, p. 691-704 14 p.

Research output: Contribution to journalArticle

126 Scopus citations

High affinity mimotope of the polysaccharide capsule of Cryptococcus neoformans identified from an evolutionary phage peptide library

Beenhouwer, D. O., May, R. J., Valadon, P. & Scharff, M. D., Dec 15 2002, In : Journal of Immunology. 169, 12, p. 6992-6999 8 p.

Research output: Contribution to journalArticle

Open Access
53 Scopus citations

High-efficiency serum-free feeder-free erythroid differentiation of human pluripotent stem cells using small molecules

Olivier, E. N., Marenah, L., McCahill, A., Condie, A., Cowan, S. & Mountford, J. C., Oct 1 2016, In : Stem Cells Translational Medicine. 5, 10, p. 1394-1405 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

High-frequency transfection of CHO cells using polybrene

Chaney, W. G., Howard, D. R., Pollard, J. W., Sallustio, S. & Stanley, P., May 1986, In : Somatic Cell and Molecular Genetics. 12, 3, p. 237-244 8 p.

Research output: Contribution to journalArticle

97 Scopus citations

High prevalence and allele burden-independent prognostic importance of p53 mutations in an inner-city MDS/AML cohort

Goel, S., Hall, J., Pradhan, K., Hirsch, C., Przychodzen, B., Shastri, A., Mantzaris, I., Janakiram, M., Battini, R., Kornblum, N., Derman, O., Gritsman, K., Al-Hafidh, J., Wang, Y., Halmos, B., Steidl, U. G., Maciejewski, J. P., Braunschweig, I. & Verma, A. K., Apr 29 2016, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

15 Scopus citations

High prevalence of pulmonary findings in computed tomographies of HTLV-1-infected patients with and without adult-T cell leukemia/lymphoma–implications for staging

Acuna-Villaorduna, A., Gonzalez-Lugo, J., Ye, B. H., Adrianzen Herrera, D. A., Sica, R. A., Shah, U., Shah, N., Kornblum, N., Braunschweig, I., Derman, O., Mantzaris, I., Shastri, A., Wang, Y., Verma, A., Zalta, B. & Janakiram, M., Nov 10 2019, In : Leukemia and Lymphoma. 60, 13, p. 3272-3276 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

High-resolution analysis of Drosophila heterochromatin organization using SuUR Su(var)3-9 double mutants

Andreyeva, E. N., Kolesnikova, T. D., Demakova, O. V., Mendez-Lago, M., Pokholkova, G. V., Belyaeva, E. S., Rossi, F., Dimitri, P., Villasante, A. & Zhimulev, I. F., Jul 31 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 31, p. 12819-12824 6 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

High-resolution chromatin immunoprecipitation (ChIP) sequencing reveals novel binding targets and prognostic role for SOX11 in mantle cell lymphoma

Kuo, P. Y., Leshchenko, W., Fazzari, M. J., Perumal, D., Gellen, T., He, T., Iqbal, J., Baumgartner-Wennerholm, S., Nygren, L., Zhang, F., Zhang, W., Suh, K. S., Goy, A., Yang, D. T., Chan, W. C., Kahl, B. S., Verma, A. K., Gascoyne, R. D., Kimby, E., Sander, B. & 3 others, Ye, B. H., Melnick, A. M. & Parekh, S., Mar 5 2015, In : Oncogene. 34, 10, p. 1231-1240 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers

Oda, M., Glass, J. L., Thompson, R. F., Mo, Y., Olivier, E. N., Figueroa, M. E., Selzer, R. R., Richmond, T. A., Zhang, X., Dannenberg, L., Green, R. D., Melnick, A., Hatchwell, E., Bouhassira, E. E., Verma, A., Suzuki, M. & Greally, J. M., 2009, In : Nucleic acids research. 37, 12, p. 3829-3839 11 p.

Research output: Contribution to journalArticle

112 Scopus citations

High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis

Yu, Y., Mo, Y., Ebenezer, D., Bhattacharyya, S., Liu, H., Sundaravel, S., Giricz, O., Wontakal, S., Cartier, J., Caces, B., Artz, A., Nischal, S., Bhagat, T., Bathon, K., Maqbool, S., Gligich, O., Suzuki, M., Steidl, U., Godley, L., Skoultchi, A. & 3 others, Greally, J., Wickrema, A. & Verma, A., Mar 29 2013, In : Journal of Biological Chemistry. 288, 13, p. 8805-8814 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Hispanic ethnicity is associated with younger age at presentation but worse survival in acute myeloid leukemia

Darbinyan, K., Shastri, A., Budhathoki, A., Helbig, D., Snyder, R., Pradhan, K., Saleh-Esa, J., Kornblum, N. S., Binder, A. F., Goel, S., Janakiram, M., Derman, O., Gritsman, K., Steidl, U., Braunschweig, I., Verma, A. & Mantzaris, I., Nov 14 2017, In : Blood Advances. 1, 24, p. 2120-2123 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Histone 1 Mutations Drive Lymphomagenesis By Inducing Primitive Stem Cell Functions and Epigenetic Instructions through Profound 3D Re-Organization of the B-Cell Genome

Yusufova, N., Teater, M. R., Soshnev, A., Kloetgen, A., Osunsade, A., Conway, J., Doane, A., Skoultchi, A., Tsirigos, A., David, Y., Allis, C. D., Cesarman, E. & Melnick, A., Nov 13 2019, In : Blood. 134, 1, 1 p.

Research output: Contribution to journalArticle

Histone H1.3 suppresses H19 noncoding RNA expression and cell growth of ovarian cancer cells

Medrzycki, M., Zhang, Y., Zhang, W., Cao, K., Pan, C., Lailler, N., McDonald, J. F., Bouhassira, E. E. & Fan, Y., Nov 15 2014, In : Cancer Research. 74, 22, p. 6463-6473 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation

Fan, Y., Nikitina, T., Zhao, J., Fleury, T. J., Bhattacharyya, R., Bouhassira, E. E., Stein, A., Woodcock, C. L. & Skoultchi, A. I., Dec 29 2005, In : Cell. 123, 7, p. 1199-1212 14 p.

Research output: Contribution to journalArticle

366 Scopus citations

Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathway

Nishiyama, M., Skoultchi, A. I. & Nakayama, K. I., Jan 2012, In : Molecular and cellular biology. 32, 2, p. 501-512 12 p.

Research output: Contribution to journalArticle

66 Scopus citations

Histone modifications and lamin A regulate chromatin protein dynamics in early embryonic stem cell differentiation

Melcer, S., Hezroni, H., Rand, E., Nissim-Rafinia, M., Skoultchi, A., Stewart, C. L., Bustin, M. & Meshorer, E., Jul 6 2012, In : Nature communications. 3, 910.

Research output: Contribution to journalArticle

93 Scopus citations

Histone Variant MacroH2A1 Plays an Isoform-Specific Role in Suppressing Epithelial-Mesenchymal Transition

Hodge, D. Q., Cui, J., Gamble, M. J. & Guo, W., Dec 1 2018, In : Scientific reports. 8, 1, 841.

Research output: Contribution to journalArticle

2 Scopus citations

HIV portends a poor prognosis in myelodysplastic syndromes

Kaner, J. D., Thibaud, S., Jasra, S., Wang, Y., Janakiram, M., Sharma, A., Sridharan, A., Elias, H., Polineni, R., Assal, A., Weiss, L., Braunschweig, I., Steidl, U., Pradhan, K., Shastri, A., Chaitowitz, M., Zingman, B., Will, B., Mantzaris, I. & Verma, A., Dec 6 2019, In : Leukemia and Lymphoma. 60, 14, p. 3529-3535 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Homologous elements hs3a and hs3b in the 3′ regulatory region of the murine immunoglobulin heavy chain (Igh) locus are both dispensable for class-switch recombination

Yan, Y., Pieretti, J., Ju, Z., Wei, S., Christin, J. R., Bah, F., Birshtein, B. K. & Eckhardt, L. A., Aug 5 2011, In : Journal of Biological Chemistry. 286, 31, p. 27123-27131 9 p.

Research output: Contribution to journalArticle

9 Scopus citations