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2008

ErbB2 induces Notch1 activity and function in breast cancer cells

Lindsay, J., Jiao, X., Sakamaki, T., Casimiro, M. C., Shirley, L. A., Tran, T. H., Ju, X., Liu, M., Li, Z., Wang, C., Katiyar, S., Rao, M., Allen, K. G., Glazer, R. I., Ge, C., Stanley, P., Lisanti, M. P., Rui, H. & Pestell, R. G., Dec 1 2008, In : Clinical and Translational Science. 1, 2, p. 107-115 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Expression of Pkd2l2 in testis is implicated in spermatogenesis

Chen, Y., Zhang, Z., Lv, X. Y., Wang, Y. D., Hu, Z. G., Sun, H., Tan, R. Z., Liu, Y. H., Bian, G. H., Xiao, Y., Li, Q. W., Yang, Q. T., Ai, J. Z., Feng, L., Yang, Y., Wei, Y. Q. & Zhou, Q., Aug 1 2008, In : Biological and Pharmaceutical Bulletin. 31, 8, p. 1496-1500 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Genes contributing to prion pathogenesis

Tamgüney, G., Giles, K., Glidden, D. V., Lessard, P., Wille, H., Tremblay, P., Groth, D. F., Yehiely, F., Korth, C., Moore, R. C., Tatzelt, J., Rubinstein, E., Boucheix, C., Yang, X., Stanley, P., Lisanti, M. P., Dwek, R. A., Rudd, P. M., Moskovitz, J., Epstein, C. J. & 13 others, Cruz, T. D., Kuziel, W. A., Maeda, N., Sap, J., Ashe, K. H., Carlson, G. A., Tesseur, I., Wyss-Coray, T., Mucke, L., Weisgraber, K. H., Mahley, R. W., Cohen, F. E. & Prusiner, S. B., Jul 2008, In : Journal of General Virology. 89, 7, p. 1777-1778 2 p.

Research output: Contribution to journalArticle

85 Scopus citations

Globin switches in yolk sac-like primitive and fetal-like definitive red blood cells produced from human embryonic stem cells

Qiu, C., Olivier, E. N., Velho, M. & Bouhassira, E. E., Feb 15 2008, In : Blood. 111, 4, p. 2400-2408 9 p.

Research output: Contribution to journalArticle

117 Scopus citations

Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery

Kiprilov, E. N., Awan, A., Desprat, R., Velho, M., Clement, C. A., Byskov, A. G., Andersen, C. Y., Satir, P., Bouhassira, E. E., Christensen, S. T. & Hirsch, R. E., Mar 10 2008, In : Journal of Cell Biology. 180, 5, p. 897-904 8 p.

Research output: Contribution to journalArticle

101 Scopus citations

Inactivation of p27Kip1 promotes chemical mouse liver tumorigenesis in the resistant strain C57BL/6J

Sun, D., Ren, H., Oertel, M., Sellers, R. S., Shafritz, D. A. & Zhu, L., Jan 1 2008, In : Molecular Carcinogenesis. 47, 1, p. 47-55 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: Potential role of chronic inflammation

Yang, K., Popova, N. V., Wan, C. Y., Lozonschi, I., Tadesse, S., Kent, S., Bancroft, L., Matise, I., Cormier, R. T., Scherer, S. J., Edelmann, W., Lipkin, M., Augenlicht, L. & Velcich, A., Sep 15 2008, In : Cancer Research. 68, 18, p. 7313-7322 10 p.

Research output: Contribution to journalArticle

74 Scopus citations

Intestinal Deletion of Pofut1 in the Mouse Inactivates Notch Signaling and Causes Enterocolitis

Guilmeau, S., Flandez, M., Bancroft, L., Sellers, R. S., Tear, B., Stanley, P. & Augenlicht, L. H., Sep 2008, In : Gastroenterology. 135, 3, p. 849-860.e6

Research output: Contribution to journalArticle

54 Scopus citations

In vivo consequences of deleting EGF repeats 8-12 including the ligand binding domain of mouse Notch1

Ge, C., Liu, T., Hou, X. & Stanley, P., May 27 2008, In : BMC Developmental Biology. 8, 48.

Research output: Contribution to journalArticle

19 Scopus citations

Involvement of cytoskeleton in Junín virus entry

Martinez, M. G., Cordo, S. M. & Candurra, N. A., Dec 1 2008, In : Virus Research. 138, 1-2, p. 17-25 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Lentiviral vectors encoding human immunodeficiency virus type 1 (HIV-1)-specific T-cell receptor genes efficiently convert peripheral blood CD8 T lymphocytes into cytotoxic T lymphocytes with potent in vitro and in vivo HIV-1-specific inhibitory activity

Joseph, A., Jian, H. Z., Follenzi, A., DiLorenzo, T., Sango, K., Hyman, J., Chen, K., Piechocka-Trocha, A., Brander, C., Hooijberg, E., Vignali, D. A., Walker, B. D. & Goldstein, H., Mar 1 2008, In : Journal of virology. 82, 6, p. 3078-3089 12 p.

Research output: Contribution to journalArticle

69 Scopus citations

Mouse fertility is enhanced by oocyte-specific loss of core 1-derived O-glycans

Williams, S. A. & Stanley, P., Jul 1 2008, In : FASEB Journal. 22, 7, p. 2273-2284 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis

Holloway, J. K., Booth, J., Edelmann, W., McGowan, C. H. & Cohen, P. E., Sep 1 2008, In : PLoS genetics. 4, 9, e1000186.

Research output: Contribution to journalArticle

112 Scopus citations

Novel roles for MLH3 deficiency and TLE6-Like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression

Chen, P. C., Kuraguchi, M., Velasquez, J., Wang, Y., Yang, K., Edwards, R., Gillen, D., Edelmann, W., Kucherlapati, R. & Lipkin, S. M., Jun 1 2008, In : PLoS genetics. 4, 6, e1000092.

Research output: Contribution to journalArticle

16 Scopus citations

Obesity enhances gastrointestinal tumorigenesis in Apc-mutant mice

Gravaghi, C., Bo, J., LaPerle, K. M. D., Quimby, F., Kucherlapati, R., Edelmann, W. & Lamprecht, S. A., Nov 1 2008, In : International Journal of Obesity. 32, 11, p. 1716-1719 4 p.

Research output: Contribution to journalArticle

28 Scopus citations

O-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors

Kim, M. L., Chandrasekharan, K., Glass, M., Shi, S., Stahl, M. C., Kaspar, B., Stanley, P. & Martin, P. T., Oct 29 2008, In : Molecular and Cellular Neuroscience. 39, 3, p. 452-464 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3′ regulatory region of the immunoglobulin heavy chain locus

Giambra, V., Volpi, S., Emelyanov, A. V., Pflugh, D., Bothwell, A. L. M., Norio, P., Fan, Y., Ju, Z., Skoultchi, A. I., Hardy, R. R., Frezza, D. & Birshtein, B. K., Oct 1 2008, In : Molecular and cellular biology. 28, 19, p. 6123-6133 11 p.

Research output: Contribution to journalArticle

40 Scopus citations

Pegylated granulocyte colony-stimulating factor mobilizes CD34+ cells with different stem and progenitor subsets and distinct functional properties in comparison with unconjugated granulocyte colony-stimulating factor

Bruns, I., Steidl, U., Fischer, J. C., Czibere, A., Kobbe, G., Raschke, S., Singh, R., Fenk, R., Rosskopf, M., Pechtel, S., Von Haeseler, A., Wernet, P., Tenen, D. G., Haas, R. & Kronenwett, R., Mar 1 2008, In : Haematologica. 93, 3, p. 347-355 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Polycystin-1 induced apoptosis and cell cycle arrest in G0/G1 phase in cancer cells

Zheng, R., Zhang, Z., Lv, X., Fan, J. M., Chen, Y., Wang, Y., Tan, R., Liu, Y. & Zhou, Q., Apr 1 2008, In : Cell Biology International. 32, 4, p. 427-435 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element

Ebralidze, A. K., Guibal, F. C., Steidl, U., Zhang, P., Lee, S., Bartholdy, B., Jorda, M. A., Petkova, V., Rosenbauer, F., Huang, G., Dayaram, T., Klupp, J., O'Brien, K. B., Will, B., Hoogenkamp, M., Borden, K. L. B., Bonifer, C. & Tenen, D. G., Aug 1 2008, In : Genes and Development. 22, 15, p. 2085-2092 8 p.

Research output: Contribution to journalArticle

121 Scopus citations

Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching

Guikema, J. E. J., Schrader, C. E., Leus, N. G. J., Ucher, A., Linehan, E. K., Werling, U., Edelmann, W. & Stavnezer, J., Dec 15 2008, In : Journal of Immunology. 181, 12, p. 8450-8459 10 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Roles of Pofut1 and O-fucose in mammalian Notch signaling

Stahl, M., Uemura, K., Ge, C., Shi, S., Tashima, Y. & Stanley, P., May 16 2008, In : Journal of Biological Chemistry. 283, 20, p. 13638-13651 14 p.

Research output: Contribution to journalArticle

128 Scopus citations

TC1 (C8orf4) is involved in ERK1/2 pathway-regulated G1- to S-phase transition

Wang, Y. D., Bian, G. H., Lv, X. Y., Zheng, R., Sun, H., Zhang, Z., Chen, Y., Li, Q. W., Xiao, Y., Yang, Q. T., Ai, J. Z., Wei, Y. Q. & Zhou, Q., Oct 1 2008, In : Journal of Biochemistry and Molecular Biology. 41, 10, p. 733-738 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

The DNA-mismatch repair enzyme hMSH2 modulates UV-B-induced cell cycle arrest and apoptosis in melanoma cells

Seifert, M., Scherer, S. J., Edelmann, W., Böhm, M., Meineke, V., Löbrich, M., Tilgen, W. & Reichrath, J., Jan 2008, In : Journal of Investigative Dermatology. 128, 1, p. 203-213 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

The herpes simplex virus receptor nectin-1 is down-regulated after trans-interaction with glycoprotein D

Stiles, K. M., Milne, R. S. B., Cohen, G. H., Eisenberg, R. J. & Krummenacher, C., Mar 30 2008, In : Virology. 373, 1, p. 98-111 14 p.

Research output: Contribution to journalArticle

40 Scopus citations
56 Scopus citations

Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression

Roa, S., Avdievich, E., Peled, J. U., MacCarthy, T., Werling, U., Fei, L. K., Kan, R., Zhao, C., Bergman, A., Cohen, P. E., Edelmann, W. & Scharff, M. D., Oct 21 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 42, p. 16248-16253 6 p.

Research output: Contribution to journalArticle

73 Scopus citations
2007

An IAP retrotransposon in the mouse ADAMTS13 gene creates ADAMTS13 variant proteins that are less effective in cleaving von Willebrand factor multimers

Zhou, W., Bouhassira, E. E. & Tsai, H. M., Aug 1 2007, In : Blood. 110, 3, p. 886-893 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

An origin of DNA replication in the promoter region of the human fragile X mental retardation (FMR1) gene

Gray, S. J., Gerhardt, J., Doerfler, W., Small, L. E. & Fanning, E., Jan 2007, In : Molecular and cellular biology. 27, 2, p. 426-437 12 p.

Research output: Contribution to journalArticle

41 Scopus citations

CG dinucleotide clustering is a species-specific property of the genome

Glass, J. L., Thompson, R. F., Khulan, B., Figueroa, M. E., Olivier, E. N., Oakley, E. J., Van Zant, G., Bouhassira, E. E., Melnick, A., Golden, A., Fazzari, M. J. & Greally, J. M., Nov 2007, In : Nucleic acids research. 35, 20, p. 6798-6807 10 p.

Research output: Contribution to journalArticle

66 Scopus citations

Characterization of Junin arenavirus cell entry

Martinez, M. G., Cordo, S. M. & Candurra, N. A., Jun 1 2007, In : Journal of General Virology. 88, 6, p. 1776-1784 9 p.

Research output: Contribution to journalArticle

62 Scopus citations

CHD1 motor protein is required for deposition of histone variant H3.3 into chromatin in vivo

Konev, A. Y., Tribus, M., Sung, Y. P., Podhraski, V., Chin, Y. L., Emelyanov, A. V., Vershilova, E., Pirrotta, V., Kadonaga, J. T., Lusser, A. & Fyodorov, D. V., Aug 24 2007, In : Science. 317, 5841, p. 1087-1090 4 p.

Research output: Contribution to journalArticle

178 Scopus citations

Competition between the ATPase Prp5 and Branch Region-U2 snRNA Pairing Modulates the Fidelity of Spliceosome Assembly

Xu, Y. Z. & Query, C. C., Dec 14 2007, In : Molecular Cell. 28, 5, p. 838-849 12 p.

Research output: Contribution to journalArticle

78 Scopus citations

Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation

Ronai, D., Iglesias-Ussel, M. D., Fan, M., Li, Z., Martin, A. & Scharff, M. D., Jan 22 2007, In : Journal of Experimental Medicine. 204, 1, p. 181-190 10 p.

Research output: Contribution to journalArticle

61 Scopus citations

Differential expression in lupus-associated IL-10 promoter single-nucleotide polymorphisms is mediated by poly(ADP-ribose) polymerase-1

Chung, E. Y., Liu, J., Zhang, Y. & Ma, X., Oct 1 2007, In : Genes and Immunity. 8, 7, p. 577-589 13 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Disrupting Skp2-cylin A interaction with a blocking peptide induces selective cancer cell killing

Ji, P., Sun, D., Wang, H., Bauzon, F. & Zhu, L., Feb 2007, In : Molecular cancer therapeutics. 6, 2, p. 684-691 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Evidence for physical interaction between the immunoglobulin heavy chain variable region and the 3′ regulatory region

Ju, Z., Volpi, S. A., Hassan, R., Martinez, N., Giannini, S. L., Gold, T. & Birshtein, B. K., Nov 30 2007, In : Journal of Biological Chemistry. 282, 48, p. 35169-35178 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Exonuclease-1 Deletion Impairs DNA Damage Signaling and Prolongs Lifespan of Telomere-Dysfunctional Mice

Schaetzlein, S., Kodandaramireddy, N. R., Ju, Z., Lechel, A., Stepczynska, A., Lilli, D. R., Clark, A. B., Rudolph, C., Wei, K., Schlegelberger, B., Schirmacher, P., Kunkel, T. A., Greenberg, R. A., Edelmann, W. & Rudolph, K. L., Sep 7 2007, In : Cell. 130, 5, p. 863-877 15 p.

Research output: Contribution to journalArticle

113 Scopus citations

Fertilization in mouse does not require terminal galactose or N-acetylglucosamine on the zona pellucida glycans

Williams, S. A., Xia, L., Cummings, R. D., McEver, R. P. & Stanley, P., Apr 15 2007, In : Journal of cell science. 120, 8, p. 1341-1349 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

Foxo3a Is Essential for Maintenance of the Hematopoietic Stem Cell Pool

Miyamoto, K., Araki, K. Y., Naka, K., Arai, F., Takubo, K., Yamazaki, S., Matsuoka, S., Miyamoto, T., Ito, K., Ohmura, M., Chen, C., Hosokawa, K., Nakauchi, H., Nakayama, K., Nakayama, K. I., Harada, M., Motoyama, N., Suda, T. & Hirao, A., Jun 7 2007, In : Cell Stem Cell. 1, 1, p. 101-112 12 p.

Research output: Contribution to journalArticle

577 Scopus citations

Fusion induced by a class II viral fusion protein, Semliki Forest virus E1, is dependent on the voltage of the target cell

Markosyan, R. M., Kielian, M. & Cohen, F. S., Oct 2007, In : Journal of virology. 81, 20, p. 11218-11225 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Global chromatin compaction limits the strength of the DNA damage response

Murga, M., Jaco, I., Fan, Y., Soria, R., Martinez-Pastor, B., Cuadrado, M., Yang, S. M., Blasco, M. A., Skoultchi, A. I. & Fernandez-Capetillo, O., Sep 24 2007, In : Journal of Cell Biology. 178, 7, p. 1101-1108 8 p.

Research output: Contribution to journalArticle

171 Scopus citations

High-resolution analysis of Drosophila heterochromatin organization using SuUR Su(var)3-9 double mutants

Andreyeva, E. N., Kolesnikova, T. D., Demakova, O. V., Mendez-Lago, M., Pokholkova, G. V., Belyaeva, E. S., Rossi, F., Dimitri, P., Villasante, A. & Zhimulev, I. F., Jul 31 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 31, p. 12819-12824 6 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Inducible overexpression of wild-type prion protein in the muscles leads to a primary myopathy in transgenic mice

Huang, S., Liang, J., Zheng, M., Li, X., Wang, M., Wang, P., Vanegas, D., Wu, D., Chakraborty, B., Hays, A. P., Chen, K., Chen, S. G., Booth, S., Cohen, M., Gambetti, P. & Kong, Q., Apr 17 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 16, p. 6800-6805 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Interleukin-10 Expression in Macrophages during Phagocytosis of Apoptotic Cells Is Mediated by Homeodomain Proteins Pbx1 and Prep-1

Chung, E. Y., Liu, J., Homma, Y., Zhang, Y., Brendolan, A., Saggese, M., Han, J., Silverstein, R., Selleri, L. & Ma, X., Dec 21 2007, In : Immunity. 27, 6, p. 952-964 13 p.

Research output: Contribution to journalArticle

Open Access
141 Scopus citations

Loss of p27Kip1 enhances tumor progression in chronic hepatocyte injury-induced liver tumorigenesis with widely ranging effects on Cdk2 or Cdc2 activation

Sun, D., Ren, H., Oertel, M., Sellers, R. S. & Zhu, L., Sep 1 2007, In : Carcinogenesis. 28, 9, p. 1859-1866 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Modifiers of epigenetic reprogramming show paternal effects in the mouse

Chong, S., Vickaryous, N., Ashe, A., Zamudio, N., Youngson, N., Hemley, S., Stopka, T., Skoultchi, A., Matthews, J., Scott, H. S., De Kretser, D., O'Bryan, M., Blewitt, M. & Whitelaw, E., May 1 2007, In : Nature Genetics. 39, 5, p. 614-622 9 p.

Research output: Contribution to journalArticle

132 Scopus citations

New liver cell mutants defective in the endocytic pathway

Stockert, R. J., Potvin, B., Nath, S., Wolkoff, A. W. & Stanley, P., Jul 1 2007, In : Biochimica et Biophysica Acta - Biomembranes. 1768, 7, p. 1741-1749 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Opposing classes of prp8 alleles modulate the transition between the catalytic steps of pre-mRNA splicing

Liu, L., Query, C. C. & Konarska, M. M., Jun 1 2007, In : Nature Structural and Molecular Biology. 14, 6, p. 519-526 8 p.

Research output: Contribution to journalArticle

70 Scopus citations

Piroxicam increases colon tumorigenesis and promotes apoptosis in Mlh1 +/-/Apc1638N/+ mice

Palmerini, E., Fan, K., Yang, K., Risio, M., Edelmann, W., Lipkin, M. & Biasco, G., Nov 1 2007, In : Anticancer Research. 27, 6 B, p. 3807-3812 6 p.

Research output: Contribution to journalArticle

6 Scopus citations