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2009

CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis

Nishiyama, M., Oshikawa, K., Tsukada, Y. I., Nakagawa, T., Iemura, S. I., Natsume, T., Fan, Y., Kikuchi, A., Skoultchi, A. I. & Nakayama, K. I., Jan 19 2009, In : Nature Cell Biology. 11, 2, p. 172-182 11 p.

Research output: Contribution to journalArticle

101 Scopus citations

Complex developmental patterns of histone modifications associated with the human β-globin switch in primary cells

Hsu, M., Richardson, C. A., Olivier, E., Qiu, C., Bouhassira, E. E., Lowrey, C. H. & Fiering, S., Jul 2009, In : Experimental Hematology. 37, 7, p. 799-806.e4

Research output: Contribution to journalArticle

10 Scopus citations
6 Scopus citations

Decreased replication origin activity in temporal transition regions

Guan, Z., Hughes, C. M., Kosiyatrakul, S., Norio, P., Sen, R., Fiering, S., Allis, C. D., Bouhassira, E. E. & Schildkraut, C. L., Nov 30 2009, In : Journal of Cell Biology. 187, 5, p. 623-635 13 p.

Research output: Contribution to journalArticle

40 Scopus citations

Developmentally regulated extended domains of DNA hypomethylation encompass highly transcribed genes of the human β-globin locus

Lathrop, M. J., Hsu, M., Richardson, C. A., Olivier, E. N., Qiu, C., Bouhassira, E. E., Fiering, S. & Lowrey, C. H., Jul 2009, In : Experimental Hematology. 37, 7, p. 807-813.e2

Research output: Contribution to journalArticle

14 Scopus citations

Differential gene expression of bone marrow-derived CD34+ cells is associated with survival of patients suffering from myelodysplastic syndrome

Prall, W. C., Czibere, A., Grall, F., Spentzos, D., Steidl, U., Giagounidis, A. A. N., Kuendgen, A., Otu, H., Rong, A., Libermann, T. A., Germing, U., Gattermann, N., Haas, R. & Aivado, M., Mar 1 2009, In : International journal of hematology. 89, 2, p. 173-187 15 p.

Research output: Contribution to journalArticle

20 Scopus citations

E1 mutants identify a critical region in the trimer interface of the Semliki Forest virus fusion protein

Liu, C. Y. & Kielian, M., Nov 1 2009, In : Journal of virology. 83, 21, p. 11298-11306 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Effect of the nonpeptide thrombopoietin receptor agonist Eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome

Will, B., Kawahara, M., Luciano, J. P., Bruns, I., Parekh, S., Erickson-Miller, C. L., Aivado, M. A., Verma, A. & Steidl, U., Oct 29 2009, In : Blood. 114, 18, p. 3899-3908 10 p.

Research output: Contribution to journalArticle

89 Scopus citations

Exogenous iron increases hemoglobin in β-thalassemic mice

Ginzburg, Y. Z., Rybicki, A. C., Suzuka, S. M., Hall, C. B., Breuer, W., Cabantchik, Z. I., Bouhassira, E. E., Fabry, M. E. & Nagel, R. L., Feb 1 2009, In : Experimental Hematology. 37, 2, p. 172-183 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Gene specificity of suppression of transgene-mediated insertional transcriptional activation by the chicken HS4 insulator

Desprat, R. & Bouhassira, E. E., Jun 18 2009, In : PloS one. 4, 6, e5956.

Research output: Contribution to journalArticle

16 Scopus citations

Genetic assessment of the importance of galectin-3 in cancer initiation, progression, and dissemination in mice

Eude-le Parco, I., Gendronneau, G., Dang, T., Delacour, D., Thijssen, V. I., Edelmann, W., Peuchmaur, M. & Poirier, F., Jan 1 2009, In : Glycobiology. 19, 1, p. 68-75 8 p.

Research output: Contribution to journalArticle

27 Scopus citations
45 Scopus citations

High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers

Oda, M., Glass, J. L., Thompson, R. F., Mo, Y., Olivier, E. N., Figueroa, M. E., Selzer, R. R., Richmond, T. A., Zhang, X., Dannenberg, L., Green, R. D., Melnick, A., Hatchwell, E., Bouhassira, E. E., Verma, A., Suzuki, M. & Greally, J. M., 2009, In : Nucleic acids research. 37, 12, p. 3829-3839 11 p.

Research output: Contribution to journalArticle

111 Scopus citations

Identification by hydrogen/deuterium exchange of structural changes in tyrosine hydroxylase associated with regulation

Wang, S., Sura, G. R., Dangott, L. J. & Fitzpatrick, P. F., Jun 9 2009, In : Biochemistry. 48, 22, p. 4972-4979 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo

Goswami, S., Philippar, U., Sun, D., Patsialou, A., Avraham, J., Wang, W., Di Modugno, F., Nistico, P., Gertler, F. B. & Condeelis, J. S., Feb 1 2009, In : Clinical and Experimental Metastasis. 26, 2, p. 153-159 7 p.

Research output: Contribution to journalArticle

80 Scopus citations

Insights into Branch Nucleophile Positioning and Activation from an Orthogonal Pre-mRNA Splicing System in Yeast

Smith, D. J., Konarska, M. M. & Query, C. C., May 15 2009, In : Molecular Cell. 34, 3, p. 333-343 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes

Dragileva, E., Hendricks, A., Teed, A., Gillis, T., Lopez, E. T., Friedberg, E. C., Kucherlapati, R., Edelmann, W., Lunetta, K. L., MacDonald, M. E. & Wheeler, V. C., Jan 1 2009, In : Neurobiology of Disease. 33, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

108 Scopus citations

Involvement of cellular proteins in Junin arenavirus entry

Martinez, M. G., Forlenza, M. B. & Candurra, N. A., Aug 6 2009, In : Biotechnology Journal. 4, 6, p. 866-870 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Involvement of Exo1b in DNA damage-induced apoptosis

Bolderson, E., Richard, D. J., Edelmann, W. & Khanna, K. K., 2009, In : Nucleic acids research. 37, 10, p. 3452-3463 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Linker histone H1 is essential for Drosophila development, the establishment of pericentric heterochromatin, and a normal polytene chromosome structure

Lu, X., Wontakal, S. N., Emelyanov, A. V., Morcillo, P., Konev, A. Y., Fyodorov, D. V. & Skoultchi, A. I., Feb 15 2009, In : Genes and Development. 23, 4, p. 452-465 14 p.

Research output: Contribution to journalArticle

61 Scopus citations

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

Sfeir, A., Kosiyatrakul, S. T., Hockemeyer, D., MacRae, S. L., Karlseder, J., Schildkraut, C. L. & de Lange, T., Jul 10 2009, In : Cell. 138, 1, p. 90-103 14 p.

Research output: Contribution to journalArticle

574 Scopus citations

Molecular characterization of hybridoma subclones spontaneously switching at high frequencies in vitro

Iglesias-Ussel, M. D., Zavadil, J. & Scharff, M. D., Oct 31 2009, In : Journal of Immunological Methods. 350, 1-2, p. 71-78 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

MSH2 ATPase domain mutation affects CTG•CAG repeat instability in transgenic mice

Tomé, S., Holt, I., Edelmann, W., Morris, G. E., Munnich, A., Pearson, C. E. & Gourdon, G., May 1 2009, In : PLoS genetics. 5, 5, e1000482.

Research output: Contribution to journalArticle

58 Scopus citations

Msh2-dependent DNA repair mitigates a unique susceptibility of B cell progenitors to c-Myc-induced lymphomas

Nepal, R. M., Tong, L., Kolaj, B., Edelmann, W. & Martin, A., Nov 3 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 44, p. 18698-18703 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Mutational and functional analysis of Large in a novel CHO glycosylation mutant

Aguilan, J. T., Sundaram, S., Nieves, E. & Stanley, P., Aug 20 2009, In : Glycobiology. 19, 9, p. 971-986 16 p.

Research output: Contribution to journalArticle

29 Scopus citations

Nuclear localization of ISWI ATPase Smarca5 (Sni2h) in mouse

Vargova, J., Vargova, K., Skoultchi, A. I. & Stopka, T., Jun 1 2009, In : Frontiers in Bioscience - Elite. 1 E, 2, p. 553-559 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo

Klapacz, J., Meira, L. B., Luchetti, D. G., Calvo, J. A., Bronson, R. T., Edelmann, W. & Samson, L. D., Jan 13 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 2, p. 576-581 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

Oocyte-specific deletion of complex and hybrid N-glycans leads to defects in preovulatory follicle and cumulus mass development

Williams, S. A. & Stanley, P., Jan 1 2009, In : Reproduction. 137, 2, p. 321-331 11 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

Perforin-mediated suppression of B-cell lymphoma

Bolitho, P., Street, S. E. A., Westwood, J. A., Edelmann, W., MacGregor, D., Waring, P., Murray, W. K., Godfrey, D. I., Trapani, J. A., Johnstone, R. W. & Smyth, M. J., Feb 24 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 8, p. 2723-2728 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Predictable dynamic program of timing of DNA replication in human cells

Desprat, R., Thierry-Mieg, D., Lailler, N., Lajugie, J., Schildkraut, C., Thierry-Mieg, J. & Bouhassira, E. E., Dec 1 2009, In : Genome research. 19, 12, p. 2288-2299 12 p.

Research output: Contribution to journalArticle

92 Scopus citations

PU.1 activation relieves GATA-1-mediated repression of Cebpa and Cbfb during leukemia differentiation

Burda, P., Curik, N., Kokavec, J., Basova, P., Mikulenkova, D., Skoultchi, A. I., Zavadil, J. & Stopka, T., Oct 1 2009, In : Molecular Cancer Research. 7, 10, p. 1693-1703 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Role of conserved histidine residues in the low-pH dependence of the Semliki Forest virus fusion protein

Qin, Z. L., Zheng, Y. & Kielian, M., May 1 2009, In : Journal of virology. 83, 9, p. 4670-4677 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

SHMTool: A webserver for comparative analysis of somatic hypermutation datasets

MacCarthy, T., Roa, S., Scharff, M. D. & Bergman, A., Jan 1 2009, In : DNA Repair. 8, 1, p. 137-141 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Success of Murine embryo transfer increased by a modified transfer pipette

Zhang, Z., Xiaoyan, L. V., Wang, Y., Chen, Y., Zheng, R., Sun, H., Bian, G., Xiao, Y., Li, Q., Yang, Q., Ai, J., Duan, J., Tan, R., Liu, Y., Yang, Y., Wei, Y. & Zhou, Q., Feb 1 2009, In : Journal of Reproduction and Development. 55, 1, p. 94-97 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations

Itano, O., Yang, K., Fan, K., Kurihara, N., Shinozaki, H., Abe, S., Jin, B., Gravaghi, C., Edelmann, W., Augenlicht, L., Kopelovich, L., Kucherlapati, R., Lamprecht, S. & Lipkin, M., Dec 4 2009, In : Carcinogenesis. 30, 11, p. 1923-1926 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

V-region mutation in vitro, in vivo, and in silico reveal the importance of the enzymatic properties of AID and the sequence environment

MacCarthy, T., Kalis, S. L., Roa, S., Pham, P., Goodman, M. F., Scharff, M. D. & Bergman, A., May 26 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 21, p. 8629-8634 6 p.

Research output: Contribution to journalArticle

29 Scopus citations
2008

Analysis of meiotic prophase I in live mouse spermatocytes

Morelli, M. A., Werling, U., Edelmann, W., Roberson, M. S. & Cohen, P. E., Aug 1 2008, In : Chromosome Research. 16, 5, p. 743-760 18 p.

Research output: Contribution to journalArticle

14 Scopus citations

An AR-Skp2 pathway for proliferation of androgen-dependent prostate-cancer cells

Wang, H., Sun, D., Ji, P., Mohler, J. & Zhu, L., Aug 1 2008, In : Journal of cell science. 121, 15, p. 2578-2587 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q

Marinovic-Terzic, I., Yoshioka-Yamashita, A., Shimodaira, H., Avdievich, E., Hunton, I. C., Kolodner, R. D., Edelmann, W. & Wang, J. Y. J., Sep 16 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 37, p. 13993-13998 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

A Stable Prefusion Intermediate of the Alphavirus Fusion Protein Reveals Critical Features of Class II Membrane Fusion

Sánchez-San Martín, C., Sosa, H. & Kielian, M., Dec 11 2008, In : Cell Host and Microbe. 4, 6, p. 600-608 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Ataxia telangiectasia-mutated damage-signaling kinase- and proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in simian virus 40-infected primate cells

Zhao, X., Madden-Fuentes, R. J., Lou, B. X., Pipas, J. M., Gerhardt, J., Rigell, C. J. & Fanning, E., Jun 1 2008, In : Journal of virology. 82, 11, p. 5316-5328 13 p.

Research output: Contribution to journalArticle

76 Scopus citations

Characterization of a novel Xenopus SH3 domain binding protein 5 like (xSH3BP5L) gene

Hu, Z. G., Chen, Y., Zhou, Q., Lv, X. Y., Zhang, Z., Wang, Y. D., Xiao, Y., Guo, H., liu, Y. H., Tan, R. Z., Li, Q. W., Bian, G. H. & Wei, Y. Q., Jan 11 2008, In : Biochemical and Biophysical Research Communications. 365, 2, p. 214-220 7 p.

Research output: Contribution to journalArticle

c-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster

Chung, E. Y., Dews, M., Cozma, D., Yu, D., Wentzel, E. A., Chang, T. C., Schelter, J. M., Cleary, M. A., Mendell, J. T. & Thomas-Tikhonenko, A., Nov 2008, In : Cancer Biology and Therapy. 7, 11, p. 1758-1764 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Comparative analysis of meiotic progression in female mice bearing mutations in genes of the DNA mismatch repair pathway

Kan, R., Sun, X., Kolas, N. K., Avdievich, E., Kneitz, B., Edelmann, W. & Cohen, P. E., Mar 2008, In : Biology of Reproduction. 78, 3, p. 462-471 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas

Ding, B. B., Yu, J. J., Yu, R. Y. L., Mendez, L. M., Shaknovich, R., Zhang, Y., Cattoretti, G. & Ye, B. H., Feb 12 2008, In : Blood. 111, 3, p. 1515-1523 9 p.

Research output: Contribution to journalArticle

211 Scopus citations

CtBP is an essential corepressor for BCL6 autoregulation

Mendez, L. M., Polo, J. M., Yu, J. J., Krupski, M., Ding, B. B., Melnick, A. & Ye, B. H., Apr 2008, In : Molecular and cellular biology. 28, 7, p. 2175-2186 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

Dietary calcium and cholecalciferol modulate cyclin D1 expression, apoptosis, and tumorigenesis in intestine of adenomatous polyposis coli 1638N/1 mice

Yang, K., Lamprecht, S. A., Shinozaki, H., Fan, K., Yang, W. C., Newmark, H. L., Kopelovich, L., Edelmann, W., Jin, B., Gravaghi, C., Augenlicht, L., Kucherlapati, R. & Lipkin, M., Sep 1 2008, In : Journal of Nutrition. 138, 9, p. 1658-1663 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Dietary induction of colonic tumors in a mouse model of sporadic colon cancer

Yang, K., Kurihara, N., Fan, K., Newmark, H., Rigas, B., Bancroft, L., Corner, G., Livote, E., Lesser, M., Edelmann, W., Velcich, A., Lipkin, M. & Augenlicht, L., Oct 1 2008, In : Cancer Research. 68, 19, p. 7803-7810 8 p.

Research output: Contribution to journalArticle

78 Scopus citations

Differential cholesterol binding by class II fusion proteins determines membrane fusion properties

Umashankar, M., Sánchez-San Martín, C., Liao, M., Reilly, B., Guo, A., Taylor, G. & Kielian, M., Sep 2008, In : Journal of virology. 82, 18, p. 9245-9253 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis

Avdievich, E., Reiss, C., Scherer, S. J., Zhang, Y., Maier, S. M., Jin, B., Hou, H., Rosenwald, A., Riedmiller, H., Kucherlapati, R., Cohen, P. E., Edelmann, W. & Kneitz, B., Mar 18 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 11, p. 4247-4252 6 p.

Research output: Contribution to journalArticle

28 Scopus citations