Research Output 1988 2020

2013
14 Citations (Scopus)

Protective properties of 2-acetylcyclopentanone in a mouse model of acetaminophen hepatotoxicity

Zhang, L., Gavin, T., Geohagen, B. C., Liu, Q., Downey, K. J. & LoPachin, R. M., Aug 2013, In : Journal of Pharmacology and Experimental Therapeutics. 346, 2, p. 259-269 11 p.

Research output: Contribution to journalArticle

Acetaminophen
Acetylcysteine
Oxidative Stress
2-acetylcyclopentanone
Imines
17 Citations (Scopus)

Protein targets of acrylamide adduct formation in cultured rat dopaminergic cells

Martyniuk, C. J., Feswick, A., Fang, B., Koomen, J. M., Barber, D. S., Gavin, T. & LoPachin, R. M., 2013, In : Toxicology Letters. 219, 3, p. 279-287 9 p.

Research output: Contribution to journalArticle

Acrylamide
Rats
Proteins
Proteome
Peptides
146 Citations (Scopus)

Regional anaesthesia to prevent chronic pain after surgery: A Cochrane systematic review and meta-analysis

Andreae, M. H. & Andreae, D. A., Nov 2013, In : British Journal of Anaesthesia. 111, 5, p. 711-720 10 p.

Research output: Contribution to journalArticle

Conduction Anesthesia
Postoperative Pain
Chronic Pain
Meta-Analysis
Randomized Controlled Trials

Reply

Straker, T. & Lebowitz, P. W., Dec 2013, In : Journal of Clinical Anesthesia. 25, 8, p. 676 1 p.

Research output: Contribution to journalArticle

Laryngoscopy
Intratracheal Intubation
Posture
Obesity
1 Citation (Scopus)

Two thousand is too many: What must be done to prevent resident attrition

Ramachandran, S., May 2013, In : Academic Medicine. 88, 5, p. 556 1 p.

Research output: Contribution to journalArticle

resident
2012
11 Citations (Scopus)

Air embolism during operative hysteroscopy: TEE-guided resuscitation

Sabsovich, I., Abel, M., Lee, C. J., Spinelli, A. D. & Abramowicz, A. E., Sep 2012, In : Journal of Clinical Anesthesia. 24, 6, p. 480-486 7 p.

Research output: Contribution to journalArticle

Air Embolism
Hysteroscopy
Resuscitation
Embolism
General Anesthesia

Anesthetic management of a surgical patient with cardiac implantable electrical device

Ramachandran, S., Janelle, G., Aleong, R., Berger, J. S., Krumerman, A. K., McKillop, M. & Weitzel, N., Sep 2012, In : Seminars in Cardiothoracic and Vascular Anesthesia. 16, 3, p. 166-175 10 p.

Research output: Contribution to journalArticle

Artificial Pacemaker
Perioperative Care
Implantable Defibrillators
Dilated Cardiomyopathy
Anesthetics
127 Citations (Scopus)

Application of the Hard and Soft, Acids and Bases (HSAB) theory to toxicant - Target interactions

LoPachin, R. M., Gavin, T., DeCaprio, A. & Barber, D. S., Feb 20 2012, In : Chemical Research in Toxicology. 25, 2, p. 239-251 13 p.

Research output: Contribution to journalArticle

Nucleophiles
Acids
Covalent bonds
Poisons
Hardness
1 Citation (Scopus)

Asystole on anesthesia induction in adults: Don't blame the Succinylcholine alone

Setty, S. & Kumar, A. B., Feb 2012, In : Minerva Anestesiologica. 78, 2, p. 258-259 2 p.

Research output: Contribution to journalArticle

Intravenous Anesthetics
Etomidate
Succinylcholine
Fentanyl
Heart Arrest
27 Citations (Scopus)

Early tracheostomy is associated with improved outcomes in patients who require prolonged mechanical ventilation after cardiac surgery

Devarajan, J., Vydyanathan, A., Xu, M., Murthy, S. M., McCurry, K. R., Sessler, D. I., Sabik, J. & Bashour, C. A., Jun 2012, In : Journal of the American College of Surgeons. 214, 6

Research output: Contribution to journalArticle

Tracheostomy
Artificial Respiration
Thoracic Surgery
Hospital Mortality
Morbidity
1 Citation (Scopus)

Hematologic Diseases

Leff, J. D., Shore-Lesserson, L. & Fischer, G. W., May 2012, Anesthesia and Uncommon Diseases: Sixth Edition. Elsevier Inc., p. 350-368 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hematologic Diseases

Hemophilia and coagulation disorders

Leff, J. D., Shore-Lesserson, L. & Kelly, R. E., Jan 18 2012, Yao & Artusio's Anesthesiology: Problem-Oriented Patient Management: Seventh Edition. Wolters Kluwer Health Adis (ESP), p. 794-811 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hemophilia A
5 Citations (Scopus)

Interventional pain management in the palliative care patient

McHugh, M. E., Miller-Saultz, D., Wuhrman, E. & Kosharskyy, B., Sep 2012, In : International Journal of Palliative Nursing. 18, 9, p. 426-433 8 p.

Research output: Contribution to journalArticle

Pain Management
Palliative Care
Opioid Analgesics
Analgesics
Therapeutics
70 Citations (Scopus)

Local anaesthetics and regional anaesthesia for preventing chronic pain after surgery.

Andreae, M. H. & Andreae, D. A., 2012, In : Cochrane database of systematic reviews (Online). 10

Research output: Contribution to journalArticle

Conduction Anesthesia
Local Anesthesia
Local Anesthetics
Chronic Pain
Thoracotomy

Mechanical circulatory assist devices (MCAD)

Leff, J. D. & Lazar, D. A., Oct 31 2012, 5-Minute Anesthesia Consult. Wolters Kluwer Health Adis (ESP)

Research output: Chapter in Book/Report/Conference proceedingChapter

Equipment and Supplies
77 Citations (Scopus)

Molecular mechanism of acrylamide neurotoxicity: Lessons learned from organic chemistry

LoPachin, R. M. & Gavin, T., 2012, In : Environmental Health Perspectives. 120, 12, p. 1650-1657 8 p.

Research output: Contribution to journalArticle

Organic Chemistry
Acrylamide
Alkenes
Oxidative Stress
Acrolein

Nerve blocks of the lower extremity

Ngeow, J. Y. F., Wang, D. & Gritsenko, K., Jan 18 2012, Yao & Artusio's Anesthesiology: Problem-Oriented Patient Management: Seventh Edition. Wolters Kluwer Health Adis (ESP), p. 1040-1057 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nerve Block
Lower Extremity
10 Citations (Scopus)

Pharmacologic management of coagulopathy in cardiac surgery: An update

Rozental, T. & Shore-Lesserson, L., Aug 2012, In : Journal of Cardiothoracic and Vascular Anesthesia. 26, 4, p. 669-679 11 p.

Research output: Contribution to journalArticle

Blood Coagulation Disorders
Cardiac Surgical Procedures
Deamino Arginine Vasopressin
Factor VIIa
Antifibrinolytic Agents
8 Citations (Scopus)

Robotic-assisted cardiac surgery

Leff, J. D. & Enriquez, L. J., 2012, In : International Anesthesiology Clinics. 50, 2, p. 78-89 12 p.

Research output: Contribution to journalArticle

Cardiac Surgical Procedures
Robotics
Cardiac Catheterization
Mitral Valve
Coronary Artery Bypass
23 Citations (Scopus)

Shoulder and head elevation improves laryngoscopic view for tracheal intubation in nonobese as well as obese individuals

Lebowitz, P. W., Shay, H., Straker, T., Rubin, D. & Bodner, S., Mar 2012, In : Journal of Clinical Anesthesia. 24, 2, p. 104-108 5 p.

Research output: Contribution to journalArticle

Intubation
Architectural Accessibility
Sternum
Laryngoscopy
Body Mass Index
2011
12 Citations (Scopus)
Aminocaproic Acid
Aprotinin
Thoracic Surgery
Kidney
Acute Kidney Injury
18 Citations (Scopus)

A randomized, open-label study of the safety and tolerability of fospropofol for patients requiring intubation and mechanical ventilation in the intensive care unit

Candiotti, K. A., Gan, T. J., Young, C., Bekker, A., Sum-Ping, S. T. J., Kahn, R., Lebowitz, P. W. & Littman, J. J., Sep 2011, In : Anesthesia and Analgesia. 113, 3, p. 550-556 7 p.

Research output: Contribution to journalArticle

Artificial Respiration
Intubation
Intensive Care Units
Safety
Propofol
19 Citations (Scopus)

A survey of airway training among U.S. and Canadian anesthesiology residency programs

Pott, L. M., Randel, G. I., Straker, T., Becker, K. D. & Cooper, R. M., Feb 2011, In : Journal of Clinical Anesthesia. 23, 1, p. 15-26 12 p.

Research output: Contribution to journalArticle

Anesthesiology
Internship and Residency
Intubation
Mental Competency
Manikins
2 Citations (Scopus)

Case 4-2011 malignant hyperthermia in cardiac surgery

Leff, J. D., Duran, H., Enriquez, L., DeRose, J., Shore-Lesserson, L., Kim, J. H., Schwinn, D. A., Podgoreanu, M. V. & Rosenberg, H., Aug 2011, In : Journal of Cardiothoracic and Vascular Anesthesia. 25, 4, p. 731-735 5 p.

Research output: Contribution to journalArticle

Malignant Hyperthermia
Cardiopulmonary Bypass
Coronary Artery Bypass
Thoracic Surgery
33 Citations (Scopus)

Early postoperative cognitive dysfunction and postoperative delirium after anaesthesia with various hypnotics: Study protocol for a randomised controlled trial - The PINOCCHIO trial

Bilotta, F., Doronzio, A., Stazi, E., Titi, L., Zeppa, I. O., Cianchi, A., Rosa, G., Paoloni, F. P., Bergese, S., Asouhidou, I., Ioannou, P., Abramowicz, A. E., Spinelli, A. D., Delphin, E. S., Ayrian, E., Zelman, V. & Lumb, P., Jul 6 2011, In : Trials. 12, 170.

Research output: Contribution to journalArticle

Delirium
Hypnotics and Sedatives
Anesthesia
Randomized Controlled Trials
Fentanyl
1 Citation (Scopus)

Linear object in the ascending aorta discovered on routine transesophageal echocardiography for coronary artery bypass graft surgery

Mueting-Nelsen, P. F., Tannous, H. & Apinis, A., Oct 2011, In : Journal of Cardiothoracic and Vascular Anesthesia. 25, 5, p. 894-896 3 p.

Research output: Contribution to journalArticle

Coronary Balloon Angioplasty
Transesophageal Echocardiography
Foreign Bodies
Coronary Artery Bypass
Artifacts
50 Citations (Scopus)

Molecular mechanism of glyceraldehyde-3-phosphate dehydrogenase inactivation by α,β-unsaturated carbonyl derivatives

Martyniuk, C. J., Fang, B., Koomen, J. M., Gavin, T., Zhang, L., Barber, D. S. & LoPachin, R. M., Dec 19 2011, In : Chemical Research in Toxicology. 24, 12, p. 2302-2311 10 p.

Research output: Contribution to journalArticle

Glyceraldehyde-3-Phosphate Dehydrogenases
Acrylamide
Cysteine
Derivatives
Acrolein

Pelvic pain

Bal, R., Diwan, S. & Gritsenko, K., 2011, Essentials of Pain Medicine. Elsevier Inc., p. 378-385 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pelvic Pain
25 Citations (Scopus)

Role of the Nrf2-ARE pathway in acrylamide neurotoxicity

Zhang, L., Gavin, T., Barber, D. S. & LoPachin, R. M., Aug 10 2011, In : Toxicology Letters. 205, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Acrylamide
Antioxidants
Proteins
Hepatocytes
Brain
29 Citations (Scopus)

β-Dicarbonyl enolates: A new class of neuroprotectants

LoPachin, R. M., Gavin, T., Geohagen, B. C., Zhang, L., Casper, D., Lekhraj, R. & Barber, D. S., Jan 2011, In : Journal of Neurochemistry. 116, 1, p. 132-143 12 p.

Research output: Contribution to journalArticle

Acrolein
Oxidative stress
Neuroprotective Agents
Aldehydes
Metal ions
2010

A case of difficulty predicting neurological deficit during thoracoabdominal aortic surgery

Leff, J. D., Sudheera, K. S. & Shore-Lesserson, L., Mar 2010, In : Seminars in Cardiothoracic and Vascular Anesthesia. 14, 1, p. 24-27 4 p.

Research output: Contribution to journalArticle

Aorta
Evoked Potentials
Intraoperative Neurophysiological Monitoring
Neurophysiological Monitoring
Spinal Cord Ischemia
1 Citation (Scopus)

Anesthesia and management of anesthetic complications of laparoscopic urological surgery

Lebowitz, P. W., Richards, M. & Bryan-Brown, C., 2010, Complications of Laparoscopic and Robotic Urologic Surgery. Springer New York, p. 7-17 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Laparoscopy
Anesthetics
Anesthesia
Ventilation
Maintenance
2 Citations (Scopus)

Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery in a Pregnant Woman With Preeclampsia

Lazar, D., Enriquez, L. J. & Rozental, T., Feb 2010, In : Journal of Cardiothoracic and Vascular Anesthesia. 24, 1, p. 112-115 4 p.

Research output: Contribution to journalArticle

Coronary Vessel Anomalies
Bland White Garland Syndrome
Cardiac Catheterization
Pre-Eclampsia
Cesarean Section
3 Citations (Scopus)

Congenitally corrected transposition of the great arteries and concomitant coronary artery and valvular disease in the adult patient

Stern, D. R., Steiner, C., Bello, R. A., Sutton, N. J., Spevack, D. M., Leyvi, G., Michler, R. E., D'Alessandro, D. A. & Weinstein, S., Nov 2010, In : Congenital Heart Disease. 5, 6, p. 629-634 6 p.

Research output: Contribution to journalArticle

Ventricular Heart Septal Defects
Coronary Artery Disease
Heart Ventricles
Situs Inversus
Tricuspid Valve
4 Citations (Scopus)

Left ventricular assist devices: An evolving state of the art

Leff, J. D. & Shore-Lesserson, L., Mar 2010, In : Seminars in Cardiothoracic and Vascular Anesthesia. 14, 1, p. 21-23 3 p.

Research output: Contribution to journalArticle

Heart-Assist Devices
Heart Failure
Heart Transplantation
Survival
Therapeutics
15 Citations (Scopus)

Single-Ventricle Patient: Pathophysiology and Anesthetic Management

Leyvi, G. & Wasnick, J. D., Feb 2010, In : Journal of Cardiothoracic and Vascular Anesthesia. 24, 1, p. 121-130 10 p.

Research output: Contribution to journalArticle

Blalock-Taussig Procedure
Fontan Procedure
Regional Blood Flow
Treatment Failure
Palliative Care
1 Citation (Scopus)

Unidentified swallowed object? When an erosion is not an erosion

Gibbs, K. E., Reddy, G. & Straker, T., May 2010, In : Surgery for Obesity and Related Diseases. 6, 3, p. 319-321 3 p.

Research output: Contribution to journalArticle

Anesthetics
Equipment and Supplies
17 Citations (Scopus)

γ-diketone axonopathy: Analyses of cytoskeletal motors and highways in CNS myelinated axons

Zhang, L., Gavin, T., DeCaprio, A. P. & LoPachin, R. M., Jun 16 2010, In : Toxicological Sciences. 117, 1, p. 180-189 10 p.

Research output: Contribution to journalArticle

Axons
Microtubules
Dyneins
Proteins
Microtubule-Associated Proteins
2009

Anesthesia for maxillary, salivary gland, mandibular and temporomandibular joint surgery

Randel, G. I. & Straker, T., Jan 1 2009, Anesthesia for Otolaryngologic Surgery. Cambridge University Press, p. 210-219 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Temporomandibular Joint
Maxilla
Salivary Glands
Anesthesia
Maxillary Sinus
9 Citations (Scopus)

Comparative covalent protein binding of 2,5-Hexanedione and 3-Acetyl-2,5-Hexanedione in the rat

DeCaprio, A. P., Kinney, E. A. & LoPachin, R. M., 2009, In : Journal of Toxicology and Environmental Health - Part A: Current Issues. 72, 14, p. 861-869 9 p.

Research output: Contribution to journalArticle

Protein Binding
Rats
Pyrroles
Proteins
Intermediate Filaments
26 Citations (Scopus)

Current perioperative management of the patient with a cardiac rhythm management device

Stone, M. E. & Apinis, A., Mar 2009, In : Seminars in Cardiothoracic and Vascular Anesthesia. 13, 1, p. 31-43 13 p.

Research output: Contribution to journalArticle

Equipment and Supplies
Perioperative Period
Implantable Defibrillators
Anesthesia
Technology
171 Citations (Scopus)

Molecular mechanisms of 4-hydroxy-2-nonenal and acrolein toxicity: Nucleophilic targets and adduct formation

LoPachin, R. M., Gavin, T., Petersen, D. R. & Barber, D. S., Sep 21 2009, In : Chemical Research in Toxicology. 22, 9, p. 1499-1508 10 p.

Research output: Contribution to journalArticle

Acrolein
Toxicity
Electrons
Nucleophiles
Oxidative stress
1 Citation (Scopus)

Pain Management for Head and Neck Surgery

Straker, T., 2009, Complications in Head and Neck Surgery with CD Image Bank. Elsevier Inc., p. 189-194 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pain Management
Neck
Head
5 Citations (Scopus)

Pulmonary Artery Flow Patterns After the Fontan Procedure Are Predictive of Postoperative Complications

Leyvi, G., Bennett, H. L. & Wasnick, J. D., Feb 2009, In : Journal of Cardiothoracic and Vascular Anesthesia. 23, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

Fontan Procedure
Pulmonary Artery
Chest Tubes
Drainage
Length of Stay
31 Citations (Scopus)

Synaptosomal toxicity and nucleophilic targets of 4-hydroxy-2-nonenal

LoPachin, R. M., Geohagen, B. C. & Gavin, T., 2009, In : Toxicological Sciences. 107, 1, p. 171-181 11 p.

Research output: Contribution to journalArticle

Toxicity
Corpus Striatum
Nucleophiles
Synaptosomes
Chemical potential
2008
58 Citations (Scopus)

Acrylamide-induced nerve terminal damage: Relevance to neurotoxic and neurodegenerative mechanisms

LoPachin, R. M. & Gavin, T., Aug 13 2008, In : Journal of Agricultural and Food Chemistry. 56, 15, p. 5994-6003 10 p.

Research output: Contribution to journalArticle

Acrylamide
acrylamides
nerve tissue
Synaptic Transmission
acrolein
100 Citations (Scopus)

Molecular mechanisms of the conjugated α,β-unsaturated carbonyl derivatives: Relevance to neurotoxicity and neurodegenerative diseases

LoPachin, R. M., Barber, D. S. & Gavin, T., Aug 2008, In : Toxicological Sciences. 104, 2, p. 235-249 15 p.

Research output: Contribution to journalArticle

Neurodegenerative diseases
Alkenes
Neurodegenerative Diseases
Derivatives
Toxicity

Physiological changes associated with pregnancy

Ciliberto, C. F., Marx, G. F. & Johnston, D., Dec 1 2008, In : Update in Anaesthesia. 24, 2, p. 72-76 5 p.

Research output: Contribution to journalArticle

Pregnancy
Uterus
Placenta
Anesthetics
Pregnant Women
11 Citations (Scopus)

Response to "Paraquat: The Red Herring of Parkinson's Disease Research"

LoPachin, R. M. & Gavin, T., May 2008, In : Toxicological Sciences. 103, 1, p. 219-221 3 p.

Research output: Contribution to journalArticle

Paraquat
Parkinsonian Disorders
Herbicides
Parkinson Disease
Research