Research Output

1997

The relevance of axonal swellings and atrophy to γ-diketone neurotoxicity: A forum position paper

LoPachin, R. M. & Lehning, E. J., Jul 16 1997, In : NeuroToxicology. 18, 1, p. 7-22 16 p.

Research output: Contribution to journalReview article

42 Scopus citations
1998

Anesthetic considerations in neonatal neurosurgical patients

Conran, A. M. & Kahana, M., 1998, In : Neurosurgery clinics of North America. 9, 1, p. 181-185 5 p.

Research output: Contribution to journalReview article

9 Scopus citations

Biochemical and Morphologic Characterization of Acrylamide Peripheral Neuropathy

Lehning, E. J., Persaud, A., Dyer, K. R., Jortner, B. S. & LoPachin, R. M., Aug 1998, In : Toxicology and Applied Pharmacology. 151, 2, p. 211-221 11 p.

Research output: Contribution to journalArticle

67 Scopus citations

Physiological changes associated with pregnancy

Ciliberto, C. F. & Marx, G. F., Jan 1 1998, In : Update in Anaesthesia. 9, p. 1-6 6 p.

Research output: Contribution to journalReview article

20 Scopus citations

The parturient with cardiac disease

Ridley, D. M. & Smiley, R. M., Jan 1 1998, In : Anesthesiology Clinics of North America. 16, 2, p. 419-440 22 p.

Research output: Contribution to journalArticle

4 Scopus citations

The relationship between extracorporeal circuit prime, albumin, and postoperative weight gain in children

Aukerman, J., Voepel-Lewis, T., Riegger, L. Q., Siewert, M., Shayevitz, J. R. & Mosca, R., Aug 1998, In : Journal of Cardiothoracic and Vascular Anesthesia. 12, 4, p. 408-414 7 p.

Research output: Contribution to journalArticle

19 Scopus citations
1999

Adenosine-induced transient asystole for management of a basilar artery aneurysm: Case report

Groff, M. W., Adams, D. C., Kahn, R. A., Kumbar, U. M., Yang, B. Y. & Bederson, J. B., Oct 1999, In : Journal of neurosurgery. 91, 4, p. 687-690 4 p.

Research output: Contribution to journalArticle

43 Scopus citations

Electron probe x-ray microanalysis: A tool for elucidating the role of ions in neuronal physiology and pathophysiology

LoPachin, R. M., Nov 1999, In : Neuroscientist. 5, 6, p. 371-382 12 p.

Research output: Contribution to journalReview article

2 Scopus citations

Experimental spinal cord injury: Spatiotemporal characterization of elemental concentrations and water contents in axons and neuroglia

Lopachin, R. M., Gaughan, C. L., Lehning, E. J., Kaneko, Y., Kelly, T. M. & Blight, A., Dec 14 1999, In : Journal of neurophysiology. 82, 5, p. 2143-2153 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

Glial cells in neurotoxicity development

Aschner, M., Allen, J. W., Kimelberg, H. K., LoPachin, R. M. & Streit, W. J., May 22 1999, In : Annual Review of Pharmacology and Toxicology. 39, p. 151-173 23 p.

Research output: Contribution to journalReview article

157 Scopus citations
11 Scopus citations

Oxygen/glucose deprivation in hippocampal slices: Altered intraneuronal elemental composition predicts structural and functional damage

Taylor, C. P., Weber, M. L., Gaughan, C. L., Lehning, E. J. & LoPachin, R. M., Jan 15 1999, In : Journal of Neuroscience. 19, 2, p. 619-629 11 p.

Research output: Contribution to journalArticle

71 Scopus citations

Parent presence does not increase the length of PICU teaching rounds

Koogler, T. K., Drum, M., Heitschmidt, M., Fuller, L., Kuntz, L., Kelleher, M. & Kahana, M., Jan 1 1999, In : Critical care medicine. 27, 12 SUPPL., p. A120

Research output: Contribution to journalArticle

Understanding the NIH review process: A brief guide to writing grant proposals in neurotoxicology

Audesirk, G., Burbacher, T., Guilarte, T. R., Laughlin, N. K., Lopachin, R., Suszkiw, J. & Tilson, H., 1999, In : Neurotoxicology. 20, 1, p. 91-98 8 p.

Research output: Contribution to journalReview article

2000

Rate of neurotoxicant exposure determines morphologic manifestations of distal axonopathy

LoPachin, R. M., Lehning, E. J., Opanashuk, L. A. & Jortner, B. S., Sep 1 2000, In : Toxicology and Applied Pharmacology. 167, 2, p. 75-86 12 p.

Research output: Contribution to journalReview article

34 Scopus citations

Redefining toxic distal axonopathies

Lopachin, R. M., Mar 15 2000, In : Toxicology Letters. 112-113, p. 23-33 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

γ-Diketone peripheral neuropathy. I. Quantitative morphometric analyses of axonal atrophy and swelling

Lehning, E. J., Jortner, B. S., Fox, J. H., Arezzo, J. C., Kitano, T. A. & Lopachin, R. M., Jun 1 2000, In : Toxicology and Applied Pharmacology. 165, 2, p. 127-140 14 p.

Research output: Contribution to journalArticle

65 Scopus citations

γ-Diketone peripheral neuropathy. II. Neurofilament subunit content

Chiu, F. C., Opanashuk, L. A., He, D. K., Lehning, E. J. & Lopachin, R. M., Jun 1 2000, In : Toxicology and Applied Pharmacology. 165, 2, p. 141-147 7 p.

Research output: Contribution to journalArticle

25 Scopus citations
2001

An investigation of a new activated clotting time "MAX-ACT" in patients undergoing extracorporeal circulation

Leyvi, G., Shore-Lesserson, L., Harrington, D., Vela-Cantos, F. & Hossain, S., 2001, In : Anesthesia and analgesia. 92, 3, p. 578-583 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Complications with 25-gauge and 27-gauge whitacre needles during combined spinal-epidural analgesia in labor

Landau, R., Ciliberto, C. F., Goodman, S. R., Kim-Lo, S. H. & Smiley, R. M., Jan 1 2001, In : International Journal of Obstetric Anesthesia. 10, 3, p. 168-171 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Determination of acrylamide and glycidamide in rat plasma by reversed-phase high performance liquid chromatography

Barber, D. S., Hunt, J., LoPachin, R. M. & Ehrich, M., Jul 15 2001, In : Journal of Chromatography B: Biomedical Sciences and Applications. 758, 2, p. 289-293 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Effects of ion channel blockade on the distribution of Na, K, Ca and other elements in oxygen-glucose deprived CA1 hippocampal neurons

LoPachin, R. M., Gaughan, C. L., Lehning, E. J., Weber, M. L. & Taylor, C. P., Apr 4 2001, In : Neuroscience. 103, 4, p. 971-983 13 p.

Research output: Contribution to journalArticle

60 Scopus citations

Embolic coronary occlusion after the arterial switch procedure

Bacha, E. A., Quinones, J., Kahana, M. D., Baron, J. M. & Hijazi, Z. M., Nov 1 2001, In : Journal of Thoracic and Cardiovascular Surgery. 122, 5, p. 1028-1030 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Glutamine administration reduces Gram-negative bacteremia in severely burned patients: A prospective, randomized, double-blind trial versus isonitrogenous control

Wischmeyer, P. E., Lynch, J., Liedel, J., Wolfson, R., Riehm, J., Gottlieb, L. & Kahana, M., Jan 1 2001, In : Critical care medicine. 29, 11, p. 2075-2080 6 p.

Research output: Contribution to journalArticle

274 Scopus citations

Glutamine induces heat shock protein and protects against endotoxin shock in the rat

Wischmeyer, P. E., Kahana, M., Wolfson, R., Ren, H., Musch, M. M. & Chang, E. B., Jun 1 2001, In : Journal of applied physiology. 90, 6, p. 2403-2410 8 p.

Research output: Contribution to journalArticle

207 Scopus citations

Glutamine reduces cytokine release, organ damage, and mortality in a rat model of endotoxemia

Wischmeyer, P. E., Kahana, M., Wolfson, R., Ren, H., Musch, M. M. & Chang, E. B., Nov 2001, In : Shock. 16, 5, p. 398-402 5 p.

Research output: Contribution to journalArticle

148 Scopus citations

Metabolism, toxicokinetics and hemoglobin adduct formation in rats following subacute and subchronic acrylamide dosing

Barber, D. S., Hunt, J. R., Ehrich, M. F., Lehning, E. J. & LoPachin, R. M., Jul 16 2001, In : Neurotoxicology. 22, 3, p. 341-353 13 p.

Research output: Contribution to journalArticle

88 Scopus citations
3 Scopus citations

Scheduling a delay between different surgeons' cases in the same operating room on the same day using upper prediction bounds for case durations

Dexter, F., Traub, R. D. & Lebowitz, P., Jan 1 2001, In : Anesthesia and analgesia. 92, 4, p. 943-946 4 p.

Research output: Contribution to journalArticle

31 Scopus citations

γ-diketone peripheral neuropathy III. Neurofilament gene expression

Opanashuk, L. A., He, D. K., Lehning, E. J. & LoPachin, R. M., Jan 1 2001, In : Neurotoxicology. 22, 2, p. 215-220 6 p.

Research output: Contribution to journalArticle

21 Scopus citations
2002

Acrylamide neuropathy I. Spatiotemporal characteristics of nerve cell damage in rat cerebellum

Lehning, E. J., Balaban, C. D., Ross, J. F., Reid, M. A. & LoPachin, R. M., Sep 2002, In : NeuroToxicology. 23, 3, p. 397-414 18 p.

Research output: Contribution to journalArticle

54 Scopus citations

Acrylamide neuropathy II. Spatiotemporal characteristics of nerve cell damage in brainstem and spinal cord

Lehning, E. J., Balaban, C. D., Ross, J. F. & LoPachin, R. M., Sep 2002, In : Neurotoxicology. 23, 3, p. 415-429 15 p.

Research output: Contribution to journalArticle

25 Scopus citations

Catheter therapy of Swiss cheese ventricular septal defects using the amplatzer muscular VSD occluder

Waight, D. J., Bacha, E. A., Kahana, M., Cao, Q. L., Heitschmidt, M. & Hijazi, Z. M., Mar 19 2002, In : Catheterization and Cardiovascular Interventions. 55, 3, p. 355-361 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Dexmedetomidine may impair cognitive testing during endovascular embolization of cerebral arteriovenous malformations: A retrospective case report series

Bustillo, M. A., Lazar, R. M., Finck, A. D., Fitzsimmons, B., Berman, M. F., Pile-Spellman, J. & Heyer, E. J., Jan 1 2002, In : Journal of Neurosurgical Anesthesiology. 14, 3, p. 209-212 4 p.

Research output: Contribution to journalArticle

46 Scopus citations

Epinephrine is not a useful addition to intrathecal fentanyl or fentanyl-bupivacaine for labor analgesia

Goodman, S. R., Kim-Lo, S. H., Ciliberto, C. F., Ridley, D. M. & Smiley, R. M., Jan 1 2002, In : Regional anesthesia and pain medicine. 27, 4, p. 374-379 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Nerve terminals as the primary site of acrylamide action: A hypothesis

LoPachin, R. M., Ross, J. F. & Lehning, E. J., May 2002, In : NeuroToxicology. 23, 1, p. 43-59 17 p.

Research output: Contribution to journalArticle

83 Scopus citations

Neurological evaluation of toxic axonopathies in rats: Acrylamide and 2,5-hexanedione

LoPachin, R. M., Ross, J. F., Reid, M. L., Das, S., Mansukhani, S. & Lehning, E. J., May 1 2002, In : Neurotoxicology. 23, 1, p. 95-110 16 p.

Research output: Contribution to journalArticle

103 Scopus citations

Reemergence of stroke deficits with midazolam challenge

Lazar, R. M., Fitzsimmons, B. F., Marshall, R. S., Berman, M. F., Bustillo, M. A., Young, W. L., Mohr, J. P., Shah, J. & Robinson, J. V., Jan 21 2002, In : Stroke. 33, 1, p. 283-285 3 p.

Research output: Contribution to journalArticle

92 Scopus citations

The role of fast axonal transport in acrylamide pathophysiology: Mechanism or epiphenomenon?

LoPachin, R. M., Jul 2002, In : NeuroToxicology. 23, 2, p. 253-257+265-270

Research output: Contribution to journalArticle

22 Scopus citations

Transcranial Doppler blood flow measurement during cesarean section in two patients with cerebral vascular disease

Smiley, R. M., Ridley, D. M., Hartmann, A., Ciliberto, C. F. & Baxi, L., Jan 1 2002, In : International Journal of Obstetric Anesthesia. 11, 3, p. 211-215 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Underdosing the epidural invalidates a good clinical trial [4]

Andreae, M., Oct 1 2002, In : Anesthesiology. 97, 4, p. 1026-1027 2 p.

Research output: Contribution to journalLetter

2 Scopus citations
2003

Acrylamide axonopathy revisited

LoPachin, R. M., Balaban, C. D. & Ross, J. F., May 1 2003, In : Toxicology and Applied Pharmacology. 188, 3, p. 135-153 19 p.

Research output: Contribution to journalReview article

122 Scopus citations

Acrylamide neuropathy. II. Spatiotemporal characteristics of nerve cell damage in brainstem and spinal cord.

Lehning, E. J., Balaban, C. D., Ross, J. F. & LoPachin, R. M., Jan 2003, In : Neurotoxicology. 24, 1, p. 109-123 15 p.

Research output: Contribution to journalArticle

13 Scopus citations

Acrylamide neuropathy. III. Spatiotemporal characteristics of nerve cell damage in forebrain.

Lehning, E. J., Balaban, C. D., Ross, J. F. & LoPachin, R. M., Jan 2003, In : Neurotoxicology. 24, 1, p. 125-136 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

Application of Proteomics to the Study of Molecular Mechanisms in Neurotoxicology

LoPachin, R. M., Jones, R. C., Patterson, T. A., Slikker, W. & Barber, D. S., Dec 2003, In : Neurotoxicology. 24, 6, p. 761-775 15 p.

Research output: Contribution to journalReview article

25 Scopus citations

Challenges facing the anesthesiologist in the emergency department

Kramer, D. C. & Grass, G., Aug 1 2003, In : Current Opinion in Anaesthesiology. 16, 4, p. 409-416 8 p.

Research output: Contribution to journalReview article

4 Scopus citations

Decompressive hemicraniectomy in a 6-year-old male after unilateral hemispheric stroke: Case report and review

Lee, M. C., Frank, J. I., Kahana, M., Tonsgard, J. H. & Frim, D. M., Apr 2 2003, In : Pediatric neurosurgery. 38, 4, p. 181-185 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Deep sedation with propofol for children undergoing ambulatory magnetic resonance imaging of the brain: Experience from a pediatric intensive care unit

Hasan, R. A., Shayevitz, J. R. & Patel, V., Dec 1 2003, In : Pediatric Critical Care Medicine. 4, 4, p. 454-458 5 p.

Research output: Contribution to journalArticle

52 Scopus citations

Erratum: Acrylamide neuropathy. II. Spatiotemporal characteristics of nerve cell damage in brainstem and spinal cord (Neuro Toxicology (2002) 23 (415-429) PII: S0161813x02000803)

Lehning, E. J., Balaban, C. D., Ross, J. F. & LoPachin, R. M., Jan 1 2003, In : NeuroToxicology. 24, 1, p. 107-136 30 p.

Research output: Contribution to journalComment/debate

Glutamine attenuates tumor necrosis factor-α release and enhances heat shock protein 72 in human peripheral blood mononuclear cells

Wischmeyer, P. E., Riehm, J., Singleton, K. D., Ren, H., Musch, M. W., Kahana, M. & Chang, E. B., Jan 1 2003, In : Nutrition. 19, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

112 Scopus citations