Anatomy & Structural Biology

Research Output

2020

A human cadaveric model for effective instruction of lateral canthotomy and cantholysis

Patel, S. R., Mishall, P. & Barmettler, A., Mar 3 2020, In : Orbit (London). 39, 2, p. 87-92 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Analysis of adult neural retina extracellular vesicle release, RNA transport and proteomic cargo

Mighty, J., Zhou, J., Benito-Martin, A., Sauma, S., Hanna, S., Onwumere, O., Shi, C., Muntzel, M., Sauane, M., Young, M., Molina, H., Cox, D. & Redenti, S., Feb 2020, In : Investigative Ophthalmology and Visual Science. 61, 2, 2761934.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

An Ultrastructural Study of the Extruded Polar Tube of Anncaliia algerae (Microsporidia)

Takvorian, P. M., Han, B., Cali, A., Rice, W. J., Gunther, L., Macaluso, F. & Weiss, L. M., Jan 1 2020, In : Journal of Eukaryotic Microbiology. 67, 1, p. 28-44 17 p.

Research output: Contribution to journalArticle

4 Scopus citations

A set of monomeric near-infrared fluorescent proteins for multicolor imaging across scales

Matlashov, M. E., Shcherbakova, D. M., Alvelid, J., Baloban, M., Pennacchietti, F., Shemetov, A. A., Testa, I. & Verkhusha, V. V., Dec 1 2020, In : Nature communications. 11, 1, 239.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Author Correction: Optogenetic control of cofilin and αTAT in living cells using Z-lock (Nature Chemical Biology, (2019), 15, 12, (1183-1190), 10.1038/s41589-019-0405-4)

Stone, O. J., Pankow, N., Liu, B., Sharma, V. P., Eddy, R. J., Wang, H., Putz, A. T., Teets, F. D., Kuhlman, B., Condeelis, J. S. & Hahn, K. M., Sep 1 2020, In : Nature Chemical Biology. 16, 9, p. 1034 1 p.

Research output: Contribution to journalComment/debate

Open Access

Bacterial Phytochrome as a Scaffold for Engineering of Receptor Tyrosine Kinases Controlled with Near-Infrared Light

Leopold, A. V., Pletnev, S. & Verkhusha, V. V., Jun 12 2020, In : Journal of Molecular Biology. 432, 13, p. 3749-3760 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Correction: Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions (Oncogene, (2019), 38, 30, (5839-5859), 10.1038/s41388-019-0844-0)

Marcus, J., Bejerano-Sagie, M., Patterson, N., Bagchi, S., Verkhusha, V. V., Connolly, D., Goldberg, G. L., Golden, A. A. J., Sharma, V. P., Condeelis, J. & Montagna, C., Feb 20 2020, In : Oncogene. 39, 8, 1 p.

Research output: Contribution to journalComment/debate

Direct measurement of vertical forces shows correlation between mechanical activity and proteolytic ability of invadopodia

Dalaka, E., Kronenberg, N. M., Liehm, P., Segall, J. E., Prystowsky, M. B. & Gather, M. C., 2020, In : Science Advances. 6, 11, eaax6912.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Dynamic Assembly and Disassembly of the Human DNA Polymerase δ Holoenzyme on the Genome In Vivo

Drosopoulos, W. C., Vierra, D. A., Kenworthy, C. A., Coleman, R. A. & Schildkraut, C. L., Feb 4 2020, In : Cell Reports. 30, 5, p. 1329-1341.e5

Research output: Contribution to journalArticle

Open Access

Force production of human cytoplasmic dynein is limited by its processivity

Brenner, S., Berger, F., Rao, L., Nicholas, M. P. & Gennerich, A., Jan 1 2020, In : Science Advances. 6, 15, eaaz4295.

Research output: Contribution to journalArticle

Open Access
Open Access
1 Scopus citations

Life Through a Lens: Technological Development and Applications in Intravital Microscopy

Niesner, R. A., Hauser, A. E. & Entenberg, D., May 1 2020, In : Cytometry Part A. 97, 5, p. 445-447 3 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations

Metal-induced neurotoxicity in a RAGE-expressing C. elegans model

Lawes, M., Pinkas, A., Frohlich, B. A., Iroegbu, J. D., Ijomone, O. M. & Aschner, M., Sep 2020, In : Neurotoxicology. 80, p. 71-75 5 p.

Research output: Contribution to journalArticle

Microscopic methods for analysis of macrophage-induced tunneling nanotubes

Carter, K. P., Segall, J. E. & Cox, D., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 273-279 7 p. (Methods in Molecular Biology; vol. 2108).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

MS2-TRIBE Evaluates Both Protein-RNA Interactions and Nuclear Organization of Transcription by RNA Editing

Biswas, J., Rahman, R., Gupta, V., Rosbash, M. & Singer, R. H., Jul 24 2020, In : iScience. 23, 7, 101318.

Research output: Contribution to journalArticle

Open Access

New generations of MS2 variants and MCP fusions to detect single mRNAs in living eukaryotic cells

Pichon, X., Robert, M. C., Bertrand, E., Singer, R. H. & Tutucci, E., 2020, Methods in Molecular Biology. Humana Press Inc., p. 121-144 24 p. (Methods in Molecular Biology; vol. 2166).

Research output: Chapter in Book/Report/Conference proceedingChapter

Novel, bilateral, two-bellied muscles span the extensor forearm, thenar eminence to insert on the proximal phalanx of the thumb: Clinical and embryological significance

Mishall, P. L., Marsh, A. N., Perez, D., Quezada, X. H., Stahl, M. C., Weinstock, R. E. & Downie, S. A., Mar 3 2020, In : Folia Morphologica. 79, 1, p. 182-187 6 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Optogenetic regulation of endogenous proteins

Redchuk, T. A., Karasev, M. M., Verkhusha, P. V., Donnelly, S. K., Hülsemann, M., Virtanen, J., Moore, H. M., Vartiainen, M. K., Hodgson, L. & Verkhusha, V. V., Dec 1 2020, In : Nature communications. 11, 1, 605.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Optogenetics: Rho GTPases activated by light in living macrophages

Hülsemann, M., Verkhusha, P. V., Guo, P., Miskolci, V., Cox, D. & Hodgson, L., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 281-293 13 p. (Methods in Molecular Biology; vol. 2108).

Research output: Chapter in Book/Report/Conference proceedingChapter

Simultaneous detection of mRNA and protein in S. cerevisiae by single-molecule FISH and immunofluorescence

Tutucci, E. & Singer, R. H., 2020, Methods in Molecular Biology. Humana Press Inc., p. 51-69 19 p. (Methods in Molecular Biology; vol. 2166).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Single-molecule imaging of transcription dynamics in somatic stem cells

Wheat, J. C., Sella, Y., Willcockson, M., Skoultchi, A. I., Bergman, A., Singer, R. H. & Steidl, U., Jul 16 2020, In : Nature. 583, 7816, p. 431-436 6 p.

Research output: Contribution to journalArticle

Single molecule mRNA fluorescent in situ hybridization combined with immunofluorescence in S. cerevisiae: Dataset and quantification

Maekiniemi, A., Singer, R. H. & Tutucci, E., Jun 2020, In : Data in Brief. 30, 105511.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

The Contribution of Race to Breast Tumor Microenvironment Composition and Disease Progression

Kim, G., Pastoriza, J. M., Condeelis, J. S., Sparano, J. A., Filippou, P. S., Karagiannis, G. S. & Oktay, M. H., Jun 30 2020, In : Frontiers in Oncology. 10, 1022.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

The role of the tumor microenvironment in tumor cell intravasation and dissemination

Borriello, L., Karagiannis, G. S., Duran, C. L., Coste, A., Oktay, M. H., Entenberg, D. & Condeelis, J. S., Aug 2020, In : European Journal of Cell Biology. 99, 6, 151098.

Research output: Contribution to journalArticle

Tumor spheroids under perfusion within a 3D microfluidic platform reveal critical roles of cell-cell adhesion in tumor invasion

Huang, Y. L., Ma, Y., Wu, C., Shiau, C., Segall, J. E. & Wu, M., Jun 15 2020, In : Scientific reports. 10, 1, p. 9648 1 p.

Research output: Contribution to journalArticle

Open Access

Validation of an automated quantitative digital pathology approach for scoring tmem, a prognostic biomarker for metastasis

Entenberg, D., Oktay, M. H., D’alfonso, T., Ginter, P. S., Robinson, B. D., Xue, X., Rohan, T. E., Sparano, J. A., Jones, J. G. & Condeelis, J. S., Apr 2020, In : Cancers. 12, 4, 846.

Research output: Contribution to journalArticle

Open Access
2019

A C. elegans Model for the Study of RAGE-Related Neurodegeneration

Pinkas, A., Lee, K. H., Chen, P. & Aschner, M., Jan 1 2019, In : Neurotoxicity Research. 35, 1, p. 19-28 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Anatomic Considerations for a Posterior Endoscopic Approach to the Cricoarytenoid Joint

Lerner, M. Z., Downie, S. A. & Tan-Geller, M., Jan 1 2019, In : Annals of Otology, Rhinology and Laryngology.

Research output: Contribution to journalArticle

A Naturally Occurring Polymorphism in the HIV-1 Tat Basic Domain Inhibits Uptake by Bystander Cells and Leads to Reduced Neuroinflammation

Ruiz, A. P., Ajasin, D. O., Ramasamy, S., DesMarais, V., Eugenin, E. A. & Prasad, V. R., Dec 1 2019, In : Scientific reports. 9, 1, 3308.

Research output: Contribution to journalArticle

3 Scopus citations

Assessing tumor microenvironment of metastasis doorway-mediated vascular permeability associated with cancer cell dissemination using intravital imaging and fixed tissue analysis

Karagiannis, G. S., Pastoriza, J. M., Borriello, L., Jafari, R., Coste, A., Condeelis, J. S., Oktay, M. H. & Entenberg, D., Jun 2019, In : Journal of Visualized Experiments. 2019, 148, e59633.

Research output: Contribution to journalArticle

1 Scopus citations

Bidirectional analysis of cryba4-crybb1 nascent transcription and nuclear accumulation of crybb3 mrnas in lens fibers

Limi, S., Zhao, Y., Guo, P., Lopez-Jones, M., Zheng, D., Singer, R. H., Skoultchi, A. I. & Cvekl, A., Jan 1 2019, In : Investigative Ophthalmology and Visual Science. 60, 1, p. 234-244 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Chemotherapy-induced metastasis: Molecular mechanisms, clinical manifestations, therapeutic interventions

Karagiannis, G. S., Condeelis, J. S. & Oktay, M. H., Sep 15 2019, In : Cancer Research. 79, 18, p. 4567-4577 11 p.

Research output: Contribution to journalReview article

8 Scopus citations

Chromophore binding to two cysteines increases quantum yield of near-infrared fluorescent proteins

Buhrke, D., Tavraz, N. N., Shcherbakova, D. M., Sauthof, L., Moldenhauer, M., Vélazquez Escobar, F., Verkhusha, V. V., Hildebrandt, P. & Friedrich, T., Dec 1 2019, In : Scientific reports. 9, 1, 1866.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Fluorescence imaging methods to investigate translation in single cells

Biswas, J., Liu, Y., Singer, R. H. & Wu, B., 2019, In : Cold Spring Harbor Perspectives in Biology. 11, 4, a032722.

Research output: Contribution to journalArticle

8 Scopus citations
Open Access
1 Scopus citations

Focusing light inside live tissue using reversibly switchable bacterial phytochrome as a genetically encoded photochromic guide star

Yang, J., Li, L., Shemetov, A. A., Lee, S., Zhao, Y., Liu, Y., Shen, Y., Li, J., Oka, Y., Verkhusha, V. V. & Wang, L. V., Dec 11 2019, In : Science Advances. 5, 12, eaay1211.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Homophilic CD44 interactions mediate tumor cell aggregation and polyclonal metastasis in patient-derived breast cancer models

Liu, X., Taftaf, R., Kawaguchi, M., Chang, Y. F., Chen, W., Entenberg, D., Zhang, Y., Gerratana, L., Huang, S., Patel, D. B., Tsui, E., Adorno-Cruz, V., Chirieleison, S. M., Cao, Y., Harney, A. S., Patel, S., Patsialou, A., Shen, Y., Avril, S., Gilmore, H. L. & 5 others, Lathia, J. D., Abbott, D. W., Cristofanilli, M., Condeelis, J. S. & Liu, H., Jan 2019, In : Cancer discovery. 9, 1, p. 96-113 18 p.

Research output: Contribution to journalArticle

36 Scopus citations

Imaging cell-type-specific dynamics of mRNAs in living mouse brain

Nwokafor, C., Singer, R. H. & Lim, H., Mar 15 2019, In : Methods. 157, p. 100-105 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Imaging Single mRNA Molecules in Mammalian Cells Using an Optimized MS2-MCP System

Vera, M., Tutucci, E. & Singer, R. H., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 3-20 18 p. (Methods in Molecular Biology; vol. 2038).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

In vivo photoacoustic multi-contrast imaging and detection of protein interactions using a small near-infrared photochromic protein

Li, L., Shemetov, A. A., Hu, P., Shcherbakova, D. M., Shi, J., Yao, J., Verkhusha, V. V. & Wang, L. V., 2019, Photons Plus Ultrasound: Imaging and Sensing 2019. Oraevsky, A. A. & Wang, L. V. (eds.). SPIE, 1087818. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10878).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion

Dufurrena, Q., Bäck, N., Mains, R., Hodgson, L., Tanowitz, H., Mandela, P., Eipper, B. & Kuliawat, R., Jan 2019, In : Journal of Molecular Endocrinology. 62, 1, p. 47-65 19 p.

Research output: Contribution to journalArticle

2 Scopus citations

Macrophages enhance 3D invasion in a breast cancer cell line by induction of tumor cell tunneling nanotubes

Carter, K. P., Hanna, S., Genna, A., Lewis, D., Segall, J. E. & Cox, D., Dec 1 2019, In : Cancer Reports. 2, 6, e1213.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Mamo decodes hierarchical temporal gradients into terminal neuronal fate

Liu, L. Y., Long, X., Yang, C. P., Miyares, R. L., Sugino, K., Singer, R. H. & Lee, T., Sep 2019, In : eLife. 8, e48056.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Mapping neurotransmitter identity in the whole-mount drosophila brain using multiplex high-throughput fluorescence in situ hybridization

Meissner, G. W., Nern, A., Singer, R. H., Wong, A. M., Malkesman, O. & Long, X., Feb 1 2019, In : Genetics. 211, 2, p. 473-482 10 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Molecular mechanism of cytoplasmic dynein tension sensing

Rao, L., Berger, F., Nicholas, M. P. & Gennerich, A., Dec 1 2019, In : Nature communications. 10, 1, 3332.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Near-Infrared Fluorescent Proteins and Their Applications

Karasev, M. M., Stepanenko, O. V., Rumyantsev, K. A., Turoverov, K. K. & Verkhusha, V. V., Jan 1 2019, In : Biochemistry (Moscow). 84, p. 32-50 19 p.

Research output: Contribution to journalReview article

8 Scopus citations

Neurotransmitter identity is acquired in a lineage-restricted manner in the Drosophila CNS

Lacin, H., Chen, H. M., Long, X., Singer, R. H., Lee, T. & Truman, J. W., Mar 2019, In : eLife. 8, e43701.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Neurotrophin receptor tyrosine kinases regulated with near-infrared light

Leopold, A. V., Chernov, K. G., Shemetov, A. A. & Verkhusha, V. V., Dec 1 2019, In : Nature communications. 10, 1, 1129.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Nopp140-mediated concentration of telomerase in Cajal bodies regulates telomere length

Bizarro, J., Bhardwaj, A., Smith, S. & Thomas Meiera, U., 2019, In : Molecular biology of the cell. 30, 26, p. 3136-3150 15 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
Open Access
2 Scopus citations