Albert Einstein College of Medicine

Projects

Projects per year 1975 1989 1990 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2021 2025

• 61 Not started
• 558 Active
• 3190 Finished

Projects per year

Search results

• Research project

  MECHANISMS OF RENAL PROSTAGLANDIN TRANSPORT

  Schuster, V. L., Schuster, V. L. & Rose, S. A.

  5/1/95 → 6/30/12

  Project: Research project

  • prostaglandins 100%
  • kidneys 89%
  • anions 47%
  • transporters 27%
  • thromboxanes 19%

• LIGAND REACTIVITY IN HEME PROTEINS

  Friedman, J. M.

  National Institute of General Medical Sciences

  9/30/92 → 8/31/97

  Project: Research project

  • ligands 100%
  • reactivity 99%
  • cryogenics 74%
  • dynamic structural analysis 50%
  • ambient temperature 38%

• COMMUNICATION PATHWAYS IN CENTRAL CAVITY MODIFIED HBS

  Friedman, J. M.

  National Heart, Lung, and Blood Institute

  9/30/96 → 8/31/02

  Project: Research project

  • Blood Substitutes 100%
  • Tryptophan 99%
  • Fluorescence 76%
  • Heme 51%
  • Fluorescent Dyes 49%

• Dynamic Calmodulin Regulation of Na Channels

  Tomaselli, G. F., Rose, S. A. & Rose, S. A.

  2/1/11 → 1/31/17

  Project: Research project

  • Calmodulin 100%
  • Myotonia 20%
  • Neuralgia 14%
  • Cardiac Arrhythmias 11%
  • Epilepsy 11%

• The Role of Omega-3 Fatty Acids in Adolescent Depression

  Gabbay, V. & Rose, S. A.

  2/1/09 → 1/31/12

  Project: Research project

  • Major Depressive Disorder 100%
  • Gyrus Cinguli 63%
  • Complementary Therapies 53%
  • Creatine 41%
  • Omega-3 Fatty Acids 38%

• Creation of the Einstein Aging Study Data Warehouse

  Katz, M. J. & Rose, S. A.

  9/15/13 → 8/31/15

  Project: Research project

  • study program 100%
  • dementia 94%
  • data quality 53%
  • pilot project 49%
  • applicant 43%

• RICIN--MECHANISM, TRANSITION STATE AND INHIBITOR DESIGN

  Schramm, V. L. & Rose, S. A.

  9/15/97 → 7/31/12

  Project: Research project

  • Ricin 100%
  • Transition State Structure 39%
  • Solvolysis 34%
  • Transition State 25%
  • Kinetic Isotope Effect 22%

• Multitargeted Microbicide Combinations to Block HIV

  Herold, B.

  Eunice Kennedy Shriver National Institute of Child Health and Human Development

  9/26/02 → 6/30/07

  Project: Research project

  • PRO 2000 100%
  • Anti-Infective Agents 49%
  • HIV 35%
  • UC 781 21%
  • Simplexvirus 11%

• MOLECULAR GENETIC STUDIES OF HUMAN COLOR VISION

  Ostrer, H.

  6/1/90 → 5/31/96

  Project: Research project

  • color vision 100%
  • pigments 59%
  • gene dosage 23%
  • X chromosome 20%
  • genes 20%

• Attenuated HSV Vaccines That Induce Protective Mucosal Antibodies

  Herold, B.

  3/1/16 → 2/28/21

  Project: Research project

  • Human Herpesvirus 2 100%
  • Human Herpesvirus 1 91%
  • Vaccines 51%
  • Viruses 36%
  • Herpes Simplex 31%

• SCID-HU ANIMAL MODEL FOR EVALUATING HIV THERAPIES

  Herold, B., McCune, J., McCune, J., Rose, S. A. & Rose, S. A.

  7/1/96 → 6/30/16

  Project: Research project

• Robust Predictor of Breast Cancer Risk

  Ostrer, H.

  9/20/17 → 6/30/21

  Project: Research project

  • Breast Neoplasms 100%
  • Germ-Line Mutation 50%
  • Mutation 50%
  • Genetic Testing 46%
  • BRCA2 Protein 37%

• Membrane protein structure modeling with experimental restraints

  Fiser, A., Rose, S. A. & Rose, S. A.

  5/1/11 → 4/30/16

  Project: Research project

  • Proteins 100%
  • Chemical shift 65%
  • Membranes 52%
  • Nuclear magnetic resonance 28%
  • Conformations 9%

• Substrate Reduction Therapies for Niemann-Pick C Disease

  Dobrenis, K., Walkley, S. U., Walkley, S. U., Rose, S. A., Rose, S. A., Rose, S. A., Rose, S. A. & Walkley, S. U.

  7/1/06 → 1/31/18

  Project: Research project

  • Type C Niemann-Pick Disease 100%
  • Glycosphingolipids 43%
  • Niemann-Pick C1 Protein 38%
  • Cholesterol 32%
  • Pregnanolone 31%

• PATHOBIOLOGY OF NEURONAL STORAGE DISEASE

  Walkley, S. U.

  12/31/89 → 8/31/96

  Project: Research project

  • Gangliosides 100%
  • Dendrites 83%
  • Synapses 74%
  • Nervous System 66%
  • alpha-Mannosidosis 48%

• PATHOGENESIS OF BRAIN DYSFUNCTION IN BATTEN'S DISEASE

  Walkley, S. U.

  9/7/92 → 8/31/96

  Project: Research project

  • Neuronal Ceroid-Lipofuscinoses 100%
  • GABAergic Neurons 42%
  • Brain 33%
  • Pyramidal Cells 24%
  • Mitochondrial Proton-Translocating ATPases 18%

• Histone Deacetylase Inhibitors for Treatment of Niemann-Pick C1 Disease

  Walkley, S. U., Ory, D., Maxfield, F. R., Maxfield, F. R., Walkley, S. U. & Walkley, S. U.

  9/15/15 → 7/31/21

  Project: Research project

  • Histone Deacetylase Inhibitors 100%
  • Niemann-Pick Diseases 33%
  • Mutation 23%
  • Mutant Proteins 22%
  • National Center for Advancing Translational Sciences (U.S.) 20%

• Support for the Rose F. Kennedy IDD Research Center

  Walkley, S. U.

  9/26/11 → 8/31/16

  Project: Research project

  • Developmental Disabilities 100%
  • Intellectual Disability 75%
  • Disabled Children 21%
  • Neurosciences 18%
  • Patient Care 13%

• Brain injury due to soccer heading and opportunities for its mitigation

  Lipton, M. L., Lipton, M. L., Rose, S. A. & Rose, S. A.

  2/1/13 → 1/31/19

  Project: Research project

  • Post-Concussion Syndrome 100%
  • Cognition 51%
  • Soccer 44%
  • Wounds and Injuries 35%
  • Brain 13%

• Modulation of Intestinal Tumorigenesis

  Augenlicht, L. H. & Rose, S. A.

  7/19/02 → 6/30/08

  Project: Research project

  • Intestinal Mucosa 100%
  • Neoplasms 81%
  • Catenins 79%
  • Mucins 68%
  • Carcinogenesis 48%

• Molecular mechanisms of T cell anergy

  Macian-Juan, F., Rose, S. A. & Rose, S. A.

  4/1/04 → 1/31/18

  Project: Research project

  • T-Lymphocytes 100%
  • Genes 56%
  • Peripheral Tolerance 55%
  • Transcriptional Activation 36%
  • Antigens 25%

• Age and Diet: Major interacting factors that drive sporadic intestinal cancer

  Augenlicht, L. H. & Rose, S. A.

  4/1/14 → 3/31/20

  Project: Research project

  • neoplasms 100%
  • stem cells 72%
  • mice 58%
  • colon 57%
  • carcinogenesis 46%

• GENE CHANGES AND CHEMOTHERAPY FOR COLON CANCER

  Augenlicht, L. H.

  9/10/92 → 7/31/98

  Project: Research project

  • cooperatives 100%
  • protocols 55%
  • adjuvants 34%
  • colorectal neoplasms 26%
  • neoplasms 25%

• Coordination of Proliferation and Apoptosis

  Augenlicht, L. H.

  7/1/01 → 6/30/03

  Project: Research project

  • apoptosis 100%
  • butyrates 90%
  • colon 64%
  • short chain fatty acids 48%
  • cells 34%

• CURCUMIN--MECHANISMS OF CHEMOPREVENTION

  Augenlicht, L. H.

  5/1/98 → 2/28/02

  Project: Research project

  • Sulindac 100%
  • Curcumin 99%
  • Non-Steroidal Anti-Inflammatory Agents 31%
  • Clinical Studies 13%
  • Volatile Fatty Acids 12%

• GENE EXPRESSION IN HUMAN COLON CANCER

  Augenlicht, L. H. & Augenlicht, L. H.

  12/31/89 → 6/30/92

  Project: Research project

  • Colonic Neoplasms 100%
  • Biopsy 67%
  • Adenoma 51%
  • Gene Expression 49%
  • Mucous Membrane 44%

• QUANTIFICATION OF GENETIC INSTABILITY IN COLON TUMORS

  Augenlicht, L. H.

  5/1/95 → 4/30/97

  Project: Research project

  • genetic instability 100%
  • neoplasms 55%
  • microsatellite repeats 53%
  • penetrance 39%
  • adjuvants 30%

• Vitamin D3 and Intestinal Tumorigenesis

  Augenlicht, L. H. & Rose, S. A.

  12/1/09 → 11/30/12

  Project: Research project

  • Cholecalciferol 100%
  • Macrophages 44%
  • Epithelial Cells 41%
  • Neoplasms 20%
  • Colonic Neoplasms 15%

• INDUCTION OF DIFFERENTIATION OF COLON CANCER CELLS

  Augenlicht, L. H.

  12/31/89 → 12/31/90

  Project: Research project

  • sodium butyrate 100%
  • butyrates 98%
  • colon 93%
  • cell lines 70%
  • carcinoma 49%

• Regulation of T Cell Responses by Chaperone-Mediated Autophagy

  Macian-Juan, F.

  6/1/16 → 5/31/21

  Project: Research project

  • Chaperone-Mediated Autophagy 100%
  • T-Cell Antigen Receptor 43%
  • T-Lymphocytes 31%
  • Autophagy 24%
  • Adaptive Immunity 8%

• SMALL INSTRUMENTATION PROGRAM

  Augenlicht, L. H.

  National Cancer Institute

  1/1/90 → 1/1/90

  Project: Research project

• Dietary Risk for Colon Cancer in the Mouse

  Augenlicht, L. H., Rose, S. A. & Rose, S. A.

  2/11/11 → 6/30/16

  Project: Research project

  • colorectal neoplasms 100%
  • neoplasms 62%
  • cholecalciferol 51%
  • mucosa 39%
  • diet 36%

• Effects of aging and HIV infection on the response to pneumococcal vaccine

  Pirofski, L. & Rose, S. A.

  5/1/14 → 4/30/20

  Project: Research project

  • HIV 100%
  • HIV Infections 71%
  • Polysaccharides 60%
  • Pneumococcal Vaccines 60%
  • B-Lymphocytes 49%

• Integrase Binding Proteins as Drug Targets to Inhibit HIV-1 Assembly

  Kalpana, G. V.

  9/1/14 → 8/31/19

  Project: Research project

  • Integrases 100%
  • HIV-1 14%
  • RNA 6%
  • Morphogenesis 6%
  • Drug Delivery Systems 6%

• Gene therapy of alcoholic liver disease

  Wang, D. Q. H.

  8/20/17 → 7/31/20

  Project: Research project

  • Alcoholic Liver Diseases 100%
  • Adeno-associated virus-2 75%
  • Ethanol 67%
  • Liver 41%
  • Triglycerides 39%

• CHOLESTEROL HOMEOSTASIS IN THE INBRED MOUSE

  Wang, D. Q. H. & Rose, S. A.

  9/1/99 → 8/31/10

  Project: Research project

  • cholelithiasis 100%
  • cholesterol 80%
  • cholesterol homeostasis 22%
  • mice 16%
  • chylomicrons 12%

• NIH Support for Conferences and Scientific Meetings

  Larsen, M. H.

  3/1/19 → 2/29/20

  Project: Research project

  • Mycobacterium 100%
  • mycobacterial diseases 86%
  • leprosy 41%
  • tuberculosis 34%
  • researchers 24%

• MODULATION OF ACUTE TOXIC LIVER INJURY

  Czaja, M. J.

  National Institutes of Health

  4/1/92 → 6/30/17

  Project: Research project

  • Liver 100%
  • Hepatocytes 96%
  • Wounds and Injuries 94%
  • hepatocytes 82%
  • Cell Death 80%

• Many Hosts of Mycobacteria Meeting VI

  Larsen, M. H., Waters, W. & Waters, W.

  2/1/15 → 8/31/15

  Project: Research project

  • Mycobacterium 100%
  • mycobacterial diseases 86%
  • leprosy 41%
  • paratuberculosis 37%
  • animal diseases 36%

• MECHANISM BASED INHIBITION OF M TUBERCULOSIS ENZYMES

  Blanchard, J. S. & Rose, S. A.

  9/30/92 → 2/28/14

  Project: Research project

  • Aspartate 100%
  • Lysine 85%
  • Chemistry 52%
  • Drug 47%

• HIV, AIDS AND OPPORTUNISTIC INFECTIONS

  Prasad, V. R., Rose, S. A. & Rose, S. A.

  6/1/95 → 7/31/21

  Project: Research project

• GASTROENTEROLOGY-HEPATOLOGY RESEARCH

  Wolkoff, A. W., Rose, S. A. & Rose, S. A.

  12/31/89 → 5/31/13

  Project: Research project

• Role of innate immunity in HIV related vascular disease: biomarkers & mechanisms

  Kaplan, R. C.

  9/15/14 → 5/31/19

  Project: Research project

  • HIV 100%
  • Cardiovascular Diseases 70%
  • HIV Infections 42%
  • Monocytes 40%
  • Innate Immunity 29%

• Enzyme-Substrate Structures and Binding Pathways

  Callender, R., Deng, H., Rose, S. A. & Rose, S. A.

  8/1/03 → 5/31/12

  Project: Research project

  • Catalysis 100%
  • Purine Nucleoside 50%
  • Spectroscopy 49%
  • Protein 48%
  • Xanthine 43%

• Enhancing Pediatric Asthma Management

  Cabana, M. D. & Rose, S. A.

  9/30/02 → 8/31/09

  Project: Research project

  • Asthma 100%
  • Adrenal Cortex Hormones 92%
  • Prescriptions 60%
  • Pediatricians 59%
  • National Heart, Lung, and Blood Institute (U.S.) 58%

• IMPLEmenting MEasures NeTwork for Child Health (IMPLEMENT for Child Health)

  Cabana, M. D.

  9/30/16 → 9/29/20

  Project: Research project

  • Pediatrics 100%
  • Sickle Cell Anemia 48%
  • Child Health 44%
  • Quality Improvement 43%
  • Medicaid 36%

• Enhancing Pediatric Asthma Management

  Cabana, M. D.

  9/30/02 → 8/31/09

  Project: Research project

  • Asthma 100%
  • Adrenal Cortex Hormones 92%
  • Prescriptions 60%
  • Pediatricians 59%
  • National Heart, Lung, and Blood Institute (U.S.) 58%

• Probiotic Outcomes in Enteric Microflora (POEM) Study

  Cabana, M. D.

  9/30/09 → 9/29/12

  Project: Research project

  • bacterial communities 100%
  • probiotics 93%
  • asthma 55%
  • Lactobacillus 39%
  • microorganisms 21%

• COMT and Developmental Memory Capacity

  Hiroi, N.

  1/18/13 → 4/30/21

  Project: Research project

  • Guaiacol 100%
  • Short-Term Memory 78%
  • Transferases 68%
  • Dopamine 28%
  • Neuronal Plasticity 23%

• THE MECHANISM OF BILE PIGMENT EXCRETION

  Roy-Chowdhury, J.

  2/1/82 → 1/31/87

  Project: Research project