Albert Einstein College of Medicine

Projects

Projects per year 1975 1989 1990 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2025

• 61 Not started
• 419 Active
• 3359 Finished

Projects per year

Search results

• Genetic variant-based drug discovery targeting conserved pathways of aging

  Vijg, J. & Suh, Y.

  9/15/17 → 4/30/22

  Project: Research project

  • Longevity 100%
  • Aged, 80 and over 54%
  • Drug Discovery 45%
  • MicroRNAs 37%
  • Healthy Aging 27%

• Genetic variant-based drug discovery targeting conserved pathways of aging

  Vijg, J., Ladiges, W., Suh, Y., Niedernhofer, L. J. & Robbins, P.

  National Institute on Aging

  9/15/17 → 4/30/22

  Project: Research project

  • Longevity 100%
  • Drug Discovery 85%
  • Drug Delivery Systems 79%
  • Aged, 80 and over 63%
  • MicroRNAs 37%

• Genetic Susceptibility to Manganese Neurotoxicity

  Aschner, M.

  1/1/16 → 12/31/17

  Project: Research project

  • Manganese 100%
  • Oxidative Stress 28%
  • Dopaminergic Neurons 13%
  • Parkinson Disease 10%
  • Winged-Helix Transcription Factors 10%

• Genetic Susceptibility to Manganese Neurotoxicity

  Aschner, M.

  National Institute of Environmental Health Sciences

  1/1/16 → 12/31/17

  Project: Research project

  • Manganese 100%
  • Genetic Predisposition to Disease 58%
  • Oxidative Stress 29%
  • Dopaminergic Neurons 14%
  • Parkinson Disease 11%

• GENETICS OF HEARING IMPAIRMENT

  Ruben, R. J.

  National Institute on Deafness and Other Communication Disorders

  7/16/90 → 6/30/91

  Project: Research project

  • hearing 100%
  • Hearing Loss 83%
  • Congresses 52%
  • Publications 36%
  • Human Genetics 21%

• GENETICS OF HEARING IMPAIRMENT

  Ruben, R. J., Iwasa, K., Braida, L., Fuchs, P., Montgomery, A. & Iwasa, K.

  7/16/90 → 6/30/91

  Project: Research project

  • Hearing Loss 100%
  • Congresses 62%
  • Publications 43%
  • Human Genetics 25%
  • Hearing Disorders 15%

• GENETICS AND BIOCHEMISTRY OF CELLULAR REGULATION

  Marmur, J. & Stanley, P.

  National Institute of General Medical Sciences

  12/31/89 → 6/30/97

  Project: Research project

• GENETICS AND BIOCHEMISTRY OF CELLULAR REGULATION

  Stanley, P.

  12/31/89 → 6/30/97

  Project: Research project

• Genetic Modulation of MeHg-Induced Oxidative Stress in the Developing Brain

  Aschner, M., Rose, S. A. & Rose, S. A.

  8/3/12 → 9/30/17

  Project: Research project

  • Astrocytes 100%
  • Oxidative Stress 79%
  • Neuroprotection 76%
  • Genetic Predisposition to Disease 73%
  • Neurons 66%

• Genetic Modulation of MeHg-Induced Oxidative Stress in the Developing Brain

  Aschner, M.

  National Institute of Environmental Health Sciences

  8/3/12 → 9/30/17

  Project: Research project

  • Astrocytes 100%
  • Oxidative Stress 79%
  • Neurons 66%
  • Transcriptional Activation 65%
  • Up-Regulation 52%

• Genetic Modifiers of Diabetes

  Chua, Jr., S. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  6/1/03 → 7/31/13

  Project: Research project

  • diabetes 100%
  • modifiers (genes) 93%
  • Leptin Receptors 91%
  • Insulin-Secreting Cells 75%
  • leptin receptors 65%

• Genetic Modifiers for 22q 11.2 Deletion Syndrome

  Morrow, B. E. & Rose, S. A.

  2/1/07 → 1/31/12

  Project: Research project

  • DiGeorge Syndrome 100%
  • Genes 48%
  • Single Nucleotide Polymorphism 40%
  • HapMap Project 34%
  • Haploinsufficiency 31%

• Genetic Modifiers for 22q 11.2 Deletion Syndrome

  Morrow, B. E.

  National Heart, Lung, and Blood Institute

  2/1/07 → 1/31/12

  Project: Research project

  • DiGeorge Syndrome 100%
  • Genes 48%
  • Single Nucleotide Polymorphism 40%
  • HapMap Project 34%
  • Haploinsufficiency 31%

• Genetic Modifers of Diabetes

  Chua, Jr., S. C. & Rose, S. A.

  6/1/03 → 7/31/13

  Project: Research project

  • Hyperglycemia 100%
  • Insulin-Secreting Cells 88%
  • Carbohydrate Metabolism 62%
  • Genes 44%
  • Perilipin-1 43%

• GENETIC ENGINEERING OF BETA CELLS FOR TRANSPLANTATION

  Brownlee, M. A.

  9/30/98 → 9/29/01

  Project: Research project

  • Genetic Engineering 100%
  • Internal Ribosome Entry Sites 57%
  • Down-Regulation 55%
  • Cre recombinase 54%
  • bcl-2 Genes 52%

• Genetic Dissection of Serotonergic Phenotypes in C. elegans

  Sze, J. Y.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  8/1/02 → 11/30/12

  Project: Research project

  • Dissection 100%
  • Neurons 86%
  • Phenotype 81%
  • Genes 44%
  • Nervous System Physiological Phenomena 42%

• Genetic Dissecting Serotonergic Phenotypes in C elegans

  Sze, J. Y.

  12/1/01 → 11/30/12

  Project: Research project

  • Serotonergic Neurons 100%
  • Serotonin 71%
  • Neurons 34%
  • Phenotype 22%
  • Neurotransmitter Agents 16%

• GENETIC CONTROL OF PROTEIN STRUCTURE AND SYNTHESIS

  Reyes Gil, M.

  12/31/89 → 4/2/03

  Project: Research project

  • Mesenchymal Stem Cells 100%
  • Iduronidase 90%
  • Mesenchymal Stem Cell Transplantation 76%
  • Hematopoietic Stem Cell Transplantation 59%
  • Animals 41%

• Genetic Basis of Syndromic and Non-Syndromic Congential Heart Defects

  Morrow, B. E., Emanuel, B. & Goldmuntz, E.

  9/24/11 → 6/30/21

  Project: Research project

  • Genome-Wide Association Study 100%
  • Research Personnel 88%
  • Technology 83%
  • Congenital Heart Defects 74%
  • Critical Pathways 74%

• Genetic Basis of Birth Defects in 22q11 Deletion Syndrome

  Morrow, B. E. & Rose, S. A.

  5/1/09 → 4/30/12

  Project: Research project

  • DiGeorge Syndrome 100%
  • Base Pairing 95%
  • Genes 54%
  • Haploinsufficiency 39%
  • Phenotype 18%

• Genetic Basis of Birth Defects in 22q11 Deletion Syndrome

  Morrow, B. E.

  National Institute of Neurological Disorders and Stroke

  5/1/09 → 4/30/12

  Project: Research project

  • 22q11 Deletion Syndrome 100%
  • DiGeorge Syndrome 62%
  • Base Pairing 59%
  • Genes 33%
  • Haploinsufficiency 24%

• Genetic and Epigenetic Determinants of Pediatric Obesity-Associated Asthma

  Rastogi, D.

  National Heart, Lung, and Blood Institute

  5/1/14 → 1/31/20

  Project: Research project

  • Pediatric Obesity 100%
  • Epigenomics 85%
  • Asthma 80%
  • Obesity 44%
  • Genetic Polymorphisms 30%

• Genetic and Epigenetic Determinants of Pediatric Obesity-Associated Asthma

  Rastogi, D.

  5/1/14 → 4/30/15

  Project: Research project

  • Asthma 100%
  • Epigenomics 59%
  • Obesity 51%
  • Genetic Polymorphisms 35%
  • Gene Expression 32%

• Genetic analysis of the P13K/Akt pathway in thyroid benign and malignant disease

  Di Cristofano, A., Rose, S. A. & Rose, S. A.

  2/1/09 → 11/30/21

  Project: Research project

  • Thyroid Gland 100%
  • Phosphatidylinositol 3-Kinases 66%
  • Thyroid Neoplasms 54%
  • Thyroid Diseases 45%
  • Thyroid Epithelial Cells 35%

• Genetic Analysis of Tbx1 in Ear Disorders

  Morrow, B. E. & Rose, S. A.

  12/1/02 → 11/30/14

  Project: Research project

  • Ear 100%
  • Inner Ear 46%
  • Genes 40%
  • DiGeorge Syndrome 39%
  • Ear Diseases 38%

• Genetic Analysis of Tbx1 in Ear Disorders

  Morrow, B. E.

  National Institute on Deafness and Other Communication Disorders

  12/1/02 → 11/30/14

  Project: Research project

  • DiGeorge Syndrome 100%
  • Inner Ear 94%
  • Ear 91%
  • Mesoderm 42%
  • Catenins 40%

• Genetic Analysis of Nematode Behavior

  Emmons, S. W. & Rose, S. A.

  8/1/03 → 11/30/14

  Project: Research project

  • sexual behavior 100%
  • searching behavior 95%
  • Caenorhabditis elegans 72%
  • mutants 54%
  • Nematoda 53%

• Genetic Analysis of Nematode Behavior

  Emmons, S. W.

  National Institute of General Medical Sciences

  8/1/03 → 11/30/14

  Project: Research project

  • genetic analysis 100%
  • sexual behavior 96%
  • searching behavior 92%
  • Nematoda 86%
  • Neurons 79%

• GENETIC ANALYSIS OF MORPHOGENESIS IN A NEMATODE

  Emmons, S. W., Emmons, S. W. & Rose, S. A.

  12/31/89 → 7/31/06

  Project: Research project

  • tail 100%
  • fans (equipment) 71%
  • mutants 70%
  • mutation 61%
  • microscopes 58%

• Genetic Analysis of Morphogenesis in a Nematode

  Emmons, S. W.

  National Institute of General Medical Sciences

  2/1/90 → 7/31/06

  Project: Research project

  • morphogenesis 100%
  • genetic analysis 95%
  • Nematoda 82%
  • homeotic genes 50%
  • genes 33%

• Genetic analysis of forebrain patterning and neurogenesis

  Hebert, J. M.

  National Institute of Mental Health

  4/1/06 → 2/28/19

  Project: Research project

  • Prosencephalon 100%
  • Neurogenesis 99%
  • Fibroblast Growth Factors 71%
  • Fibroblast Growth Factor Receptors 54%
  • Cerebrum 46%

• Genetic Analysis of Forebrain Patterning &Neurogenesis

  Hebert, J. M., Rose, S. A. & Rose, S. A.

  4/1/06 → 2/28/19

  Project: Research project

  • Cerebrum 100%
  • Holoprosencephaly 98%
  • Forebrain Defects 43%
  • Embryonic Structures 37%
  • Bone Morphogenetic Protein Receptors 33%

• GENETICALLY MODIFIED HEPATOCYTES TO ACHIEVE SUCCESS IN LIVER CELL TRANSPLANTATION

  Zhu, L., Shafritz, D. & Zhu, L.

  9/15/14 → 7/31/20

  Project: Research project

  • Yap 100%
  • hepatocytes 60%
  • liver 34%
  • stem cells 27%
  • tamoxifen 18%

• GENETICALLY MODIFIED HEPATOCYTES TO ACHIEVE SUCCESS IN LIVER CELL TRANSPLANTATION

  Shafritz, D. & Zhu, L.

  National Institute of Diabetes and Digestive and Kidney Diseases

  9/15/14 → 7/31/20

  Project: Research project

  • Yap 100%
  • cell transplantation 74%
  • hepatocytes 53%
  • liver 34%
  • stem cells 27%

• GENETICALLY ENGINEERED VIRUSES TO TREAT MALIGNANT NERVOUS SYSTEM TUMORS

  Minniti, C. P.

  1/1/01 → 2/29/96

  Project: Research project

  • Simplexvirus 100%
  • Nervous System Neoplasms 97%
  • Viruses 61%
  • Neoplasms 59%
  • Thymidine Kinase 55%

• GENETICALLY ALTERED RTS PREPARE BETTER CDNA LIBRARIES

  Prasad, V. R.

  9/30/97 → 9/29/99

  Project: Research project

  • RNA-Directed DNA Polymerase 100%
  • Gene Library 68%
  • HIV-1 37%
  • Moloney murine leukemia virus 29%
  • Nucleocapsid Proteins 29%

• GENETICALLY ALTERED RTS PREPARE BETTER CDNA LIBRARIES

  Prasad, V. R.

  National Cancer Institute

  9/30/97 → 9/29/99

  Project: Research project

  • RNA-Directed DNA Polymerase 100%
  • Gene Library 68%
  • Libraries 61%
  • HIV-1 37%
  • Moloney murine leukemia virus 29%

• Gene therapy of alcoholic liver disease

  Wang, D. Q. H.

  8/20/17 → 7/31/20

  Project: Research project

  • Alcoholic Liver Diseases 100%
  • Adeno-associated virus-2 75%
  • Ethanol 67%
  • Liver 41%
  • Triglycerides 39%

• Gene therapy of alcoholic liver disease

  Wang, D. Q. H.

  National Institute on Alcohol Abuse and Alcoholism

  8/20/17 → 7/31/20

  Project: Research project

  • Alcoholic Liver Diseases 100%
  • Adeno-associated virus-2 75%
  • Ethanol 67%
  • Genetic Therapy 62%
  • Liver 41%

• GENE THERAPY FOR INHERITED JAUNDICE

  Roy-Chowdhury, J.

  National Institute of Diabetes and Digestive and Kidney Diseases

  8/1/93 → 7/31/09

  Project: Research project

  • Crigler-Najjar Syndrome 100%
  • Gunn Rats 63%
  • Genetic Therapy 57%
  • Jaundice 54%
  • Transgenes 39%

• Gene-SNP haplotype analysis of an aging population

  Suh, Y.

  5/1/04 → 4/30/06

  Project: Research project

  • single nucleotide polymorphism 100%
  • longitudinal studies 43%
  • genes 37%
  • phenotype 35%
  • disease susceptibility 20%

• GENES MEDIATING CELL COMPETITION AND SURVIVAL

  Baker, N. E.

  National Institute of General Medical Sciences

  5/1/98 → 4/30/01

  Project: Research project

  • cells 100%
  • neurodegenerative diseases 93%
  • genes 87%
  • programmed cell death 82%
  • cell division 65%

• GENES MEDIATING CELL COMPETITION AND SURVIVAL

  Baker, N. E.

  5/1/98 → 4/30/01

  Project: Research project

  • cells 100%
  • neurodegenerative diseases 80%
  • programmed cell death 70%
  • cell division 55%
  • homeostasis 54%

• Gene regulation of retinal cell differentiation

  Liu, W. & Rose, S. A.

  5/1/13 → 8/31/21

  Project: Research project

  • Stem Cells 100%
  • Photoreceptor Cells 85%
  • Cell Differentiation 77%
  • Otx Transcription Factors 26%
  • Retina 23%

• Gene regulation in metastasis and new methods to analyze its microarray profiles

  Zhang, Z.

  U.S. National Library of Medicine

  9/30/07 → 9/29/10

  Project: Research project

  • Microarrays 100%
  • Gene expression 96%
  • metastasis 90%
  • neoplasms 47%
  • Tumors 44%

• Gene regulation in metastasis and new methods to analyze its microarray profiles

  Zhang, Z.

  9/30/07 → 9/29/14

  Project: Research project

  • Tumors 100%
  • Gene expression 53%
  • Genomics 50%
  • DNA 50%
  • Microarrays 37%

• Gene regulation in metastasis and new methods to analyze its microarray profiles

  Zhang, Z.

  U.S. National Library of Medicine

  10/1/10 → 9/29/14

  Project: Research project

  • metastasis 100%
  • neoplasms 46%
  • genes 24%
  • copy number variation 23%
  • methodology 18%

• Generation of transgenic zebrafish to study electrical synaptic transmission

  Pereda, A. E. & Rose, S. A.

  9/16/13 → 8/31/16

  Project: Research project

  • Gap Junctions 100%
  • Electrical Synapses 90%
  • Zebrafish 88%
  • Synapses 66%
  • connexin 36 48%

• Generation of transgenic zebrafish to study electrical synaptic transmission

  Pereda, A. E.

  National Institute of Neurological Disorders and Stroke

  9/16/13 → 8/31/16

  Project: Research project

  • Gap Junctions 100%
  • Electrical Synapses 90%
  • Zebrafish 88%
  • Synaptic Transmission 68%
  • Synapses 66%

• Generation of floxed-AKT3 mice to study the role in neuroinflammatory diseases

  Shafit-Zagardo, B.

  National Institute of Neurological Disorders and Stroke

  4/1/14 → 3/31/16

  Project: Research project

  • Oligodendroglia 100%
  • Multiple Sclerosis 80%
  • Autoimmune Experimental Encephalomyelitis 70%
  • Demyelinating Diseases 63%
  • Mouse Mog protein 56%